Patents by Inventor Josef Prassler

Josef Prassler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210317190
    Abstract: The present invention provides synthetic canine antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries.
    Type: Application
    Filed: April 22, 2021
    Publication date: October 14, 2021
    Inventors: Thomas Tiller, Markus Waldhuber, Ralf Strohner, Kathrin Ladetzki-Baehs, Josef Prassler
  • Patent number: 11085038
    Abstract: The invention relates to novel polypeptide libraries that are conformationally constrained in an anti-parallel, helix-turn-helix arrangement. The invention further relates to methods of generating and screening such libraries for biological, pharmaceutical and other uses.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: August 10, 2021
    Assignee: MORPHOSYS AG
    Inventors: Roger Müller, Andreas Bültmann, Josef Prassler, Markus Moosmeier
  • Patent number: 11014978
    Abstract: The present invention provides synthetic canine antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: May 25, 2021
    Assignee: MORPHOSYS AG
    Inventors: Thomas Tiller, Markus Waldhuber, Ralf Strohner, Kathrin Ladetzki-Baehs, Josef Prassler
  • Patent number: 10919955
    Abstract: The present invention provides synthetic rodent antibody libraries, such as mouse or rat antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries and variants of such antibodies.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: February 16, 2021
    Assignee: MORPHOSYS AG
    Inventors: Josef Prassler, David Ott, Stefanie Thiel, Yvonne Stark, Ute Keck, Thomas Pietzonka, Hilmar Ebersbach
  • Publication number: 20200385705
    Abstract: The present invention relates to methods for displaying cyclic peptides on the surface of bacteriophage particles and collections thereof.
    Type: Application
    Filed: August 12, 2020
    Publication date: December 10, 2020
    Inventors: Johannes Herbert Urban, Markus Andreas Moosmeier, Tjibbe Bosma, Josef Prassler
  • Patent number: 10774323
    Abstract: The present invention relates to methods for displaying cyclic peptides on the surface of bacteriophage particles and collections thereof.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: September 15, 2020
    Assignee: LANTHIOPEP B.V.
    Inventors: Johannes Herbert Urban, Markus Andreas Moosmeier, Tjibbe Bosma, Josef Prassler
  • Publication number: 20200231963
    Abstract: The invention relates to novel polypeptide libraries that are conformationally constrained in an anti-parallel, helix-turn-helix arrangement. The invention further relates to methods of generating and screening such libraries for biological, pharmaceutical and other uses.
    Type: Application
    Filed: April 8, 2020
    Publication date: July 23, 2020
    Inventors: Roger Müller, Andreas Bültmann, Josef Prassler, Markus Moosmeier
  • Publication number: 20200223904
    Abstract: The present invention provides synthetic canine antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries.
    Type: Application
    Filed: June 21, 2018
    Publication date: July 16, 2020
    Inventors: Thomas Tiller, Markus Waldhuber, Ralf Strohner, Kathrin Ladetzki-Baehs, Josef Prassler
  • Patent number: 10655125
    Abstract: The invention relates to novel polypeptide libraries that are conformationally constrained in an anti-parallel, helix-turn-helix arrangement. The invention further relates to methods of generating and screening such libraries for biological, pharmaceutical and other uses.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: May 19, 2020
    Assignee: MOR0059US.NP
    Inventors: Roger Müller, Andreas Bültmann, Josef Prassler, Markus Moosmeier
  • Patent number: 10647757
    Abstract: The present disclosure enables methods of identifying the VH and VL class pairs in the human immune repertoire, determining the VH and VL class pairs that are most prevalent and those having favorable biophysical properties. More specifically, the collections of the present disclosure comprise the most prevalent and/or preferred VH and VL class pairings with highly diversified CDRs.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: May 12, 2020
    Assignee: MORPHOSYS AG
    Inventors: Markus Enzelberger, Stefanie Urlinger, Thomas Tiller, Josef Prassler, Tanja Herrmann
  • Publication number: 20190270981
    Abstract: The invention relates to novel polypeptide libraries that are conformationally constrained in an anti-parallel, helix-turn-helix arrangement. The invention further relates to methods of generating and screening such libraries for biological, pharmaceutical and other uses.
    Type: Application
    Filed: March 3, 2017
    Publication date: September 5, 2019
    Inventors: Roger Müller, Andreas Bültmann, Josef Prassler, Markus Moosmeier
  • Publication number: 20180051276
    Abstract: The present invention relates to methods for displaying cyclic peptides on the surface of bacteriophage particles and collections thereof.
    Type: Application
    Filed: December 21, 2015
    Publication date: February 22, 2018
    Inventors: Johannes Herbert Urban, Markus Andreas Moosmeier, Tjibbe Bosma, Josef Prassler
  • Publication number: 20170218048
    Abstract: The present disclosure enables methods of identifying the VH and VL class pairs in the human immune repertoire, determining the VH and VL class pairs that are most prevalent and those having favorable biophysical properties. More specifically, the collections of the present disclosure comprise the most prevalent and/or preferred VH and VL class pairings with highly diversified CDRs.
    Type: Application
    Filed: March 3, 2017
    Publication date: August 3, 2017
    Inventors: Markus Enzelberger, Stefanie Urlinger, Thomas Tiller, Josef Prassler, Tanja Herrmann
  • Publication number: 20170183395
    Abstract: The present invention provides synthetic rodent antibody libraries, such as mouse or rat antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries and variants of such antibodies.
    Type: Application
    Filed: March 10, 2017
    Publication date: June 29, 2017
    Inventors: Josef Prassler, David Ott, Stefanie Thiel, Yvonne Stark, Ute Keck, Thomas Pietzonka, Hilmar Ebersbach
  • Patent number: 9650432
    Abstract: The present invention provides synthetic rodent antibody libraries, such as mouse or rat antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries and variants of such antibodies.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: May 16, 2017
    Assignee: MORPHOSYS AG
    Inventors: Josef Prassler, David Ott, Stefanie Thiel, Yvonne Stark, Ute Keck, Thomas Pietzonka, Hilmar Ebersbach
  • Patent number: 9624293
    Abstract: The present disclosure enables methods of identifying the VH and VL class pairs in the human immune repertoire, determining the VH and VL class pairs that are most prevalent and those having favorable biophysical properties. More specifically, the collections of the present disclosure comprise the most prevalent and/or preferred VH and VL class pairings with highly diversified CDRs.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: April 18, 2017
    Assignee: MORPHOSYS AG
    Inventors: Markus Enzelberger, Stefanie Urlinger, Thomas Tiller, Josef Prassler, Tanja Herrmann
  • Patent number: 9062097
    Abstract: The present invention relates to methods for the formation of inter-molecular disulphide bonds, including (poly)peptides/proteins, nucleic acids, vectors, host cells and bacteriophages used in these methods. Furthermore the invention relates to the use of this method for the improved display of (poly)peptides/proteins on the surface of bacteriophage particles.
    Type: Grant
    Filed: August 21, 2008
    Date of Patent: June 23, 2015
    Assignee: Morpho Sys AG
    Inventors: Josef Prassler, Yvonne Stark
  • Publication number: 20140255415
    Abstract: The present invention provides a binding molecule which is capable of binding to the rat, cynomolgus monkey and human LINGO polypeptide, a polynucleotide encoding such binding molecule; an expression vector comprising said polynucleotide; an expression system comprising a polynucleotide capable of producing a binding molecule; an isolated host cell which comprises an expression system as defined above; the use of such binding molecule as a pharmaceutical, especially in the treatment to promote axonal regeneration/plasticity; a pharmaceutical composition comprising said binding molecule; and a method of treatment of diseases associated with axonal degeneration and demyelination.
    Type: Application
    Filed: May 19, 2014
    Publication date: September 11, 2014
    Applicant: NOVARTIS AG
    Inventors: Marta CORTES-CROS, Ingo Markus KLAGGE, Josef PRASSLER, Adrian Robert WALMSLEY, William Leonard WISHART
  • Publication number: 20140163208
    Abstract: The present disclosure enables methods of identifying the VH and VL class pairs in the human immune repertoire, determining the VH and VL class pairs that are most prevalent and those having favorable biophysical properties. More specifically, the collections of the present disclosure comprise the most prevalent and/or preferred VH and VL class pairings with highly diversified CDRs.
    Type: Application
    Filed: January 31, 2014
    Publication date: June 12, 2014
    Applicant: MorphoSys AG
    Inventors: Markus Enzelberger, Stefanie Urlinger, Thomas Tiller, Josef Prassler, Tanja Herrmann
  • Patent number: 8685896
    Abstract: The present disclosure enables methods of identifying the VH and VL class pairs in the human immune repertoire, determining the VH and VL class pairs that are most prevalent and those having favorable biophysical properties. More specifically, the collections of the present disclosure comprise the most prevalent and/or preferred VH and VL class pairings with highly diversified CDRs.
    Type: Grant
    Filed: May 29, 2010
    Date of Patent: April 1, 2014
    Assignee: MorphoSys AG
    Inventors: Markus Enzelberger, Stefanie Urlnger, Thomas Tiller, Josef Prassler, Tanja Herrmann