Abstract: Systems and methods to aid a welder or welding student. A system may provide a real-world arc welding system or a virtual reality arc welding system along with a computerized eyewear device having a head-up display (HUD). The computerized eyewear device may be worn by a user under a conventional welding helmet as eye glasses are worn and may wirelessly communicate with a welding power source of a real-world arc welding system or a programmable processor-based subsystem of a virtual reality arc welding system.

Abstract: A system includes one or more processors that are configured to obtain a constraint on movement for a first vehicle system along a route. The constraint is based on movement of a separate second vehicle system that is concurrently traveling along the same route. The processor(s) are configured to determine a speed profile that designates speeds for the first vehicle system according to at least one of distance, location, or time based on the constraint such that the first vehicle system maintains a designated spacing from the second vehicle system along the route.

Abstract: An eye-tracking system includes an at least partially transparent visible light waveguide having a visible light display region configured to emit visible light to an eye of a user. A light source is configured to emit at least infrared (IR) light that travels along an IR light path to the eye of the user. A microelectromechanical system (MEMS) projector positioned in the IR light path directs the IR light. At least one diffractive input coupler on an input end of the IR light path downstream of the MEMS projector diffracts at least a portion of the IR light. At least one diffractive output coupler positioned in the IR light path downstream of the diffractive input coupler receives the IR light and directs the IR light toward the eye. At least one sensor is configured to receive the IR light after being reflected by the eye.

Abstract: A system for selectively disabling highway crossing equipment includes a timer for controlling a maximum out of service time for the highway crossing equipment, a switch for controlling disablement of the highway crossing equipment, and control circuitry responsive to the timer and the switch. The control circuitry disables the highway crossing equipment in response to an input received from the switch before the maximum out of service time has been reached and re-enables the highway crossing equipment in response to a subsequent input from the switch received before the maximum out of service time has been reached. The control circuitry places the highway crossing equipment in a failsafe condition when the maximum out of service time has been reached without receiving the subsequent input from the switch.

Abstract: The disclosure provides a method for treating a subject afflicted with a tumor derived from a small cell lung cancer (SCLC) having a high tumor mutational burden (TMB) status comprising administering to the SCLC Study TMB subject a monotherapy comprising an anti-PD-1 antibody or a combination therapy comprising an anti-PD-1 antibody and an anti-CTLA-4 antibody. The present disclosure also provides a method for identifying a subject suitable for treatment with an anti-PD-1 antibody or a combination therapy comprising an anti-PD-1 antibody and an anti-CTLA-4 antibody comprising measuring a TMB status of a biological sample of the subject. A high TMB status identifies the patient as suitable for treatment with an anti-PD-1 antibody or antigen-binding portion thereof. The TMB status can be determined by sequencing nucleic acids in the tumor and identifying a genomic alteration, e.g., a somatic nonsynonymous mutation, in the sequenced nucleic acids.

Abstract: Techniques are described herein for efficient movement of data from a source memory to a destination memory. In an embodiment, in response to a particular memory location being pushed into a first register within a first register space, the first set of electronic circuits accesses a descriptor stored at the particular memory location. The descriptor indicates a width of a column of tabular data, a number of rows of tabular data, and one or more tabular data manipulation operations to perform on the column of tabular data. The descriptor also indicates a source memory location for accessing the tabular data and a destination memory location for storing data manipulation result from performing the one or more data manipulation operations on the tabular data.

Abstract: A luminaire having a substantially two-piece housing with a first portion and a second portion, for example a cover and a base. The cover receives one or more control components. The base receives a light emitter assembly and the control component assembly is operatively connected to the lighter emitter assembly to control the light output therefrom. A lens assembly can be connected to the bottom of the base. Different mounting components can be connected to cover to connect the luminaire 10 to a support.

Abstract: The disclosed invention relates to the novel composition of matter that allows for the controlled release of highly active compounds to be delivered to a desired site. This novel composition utilizes the immune system to allow for the controlled release of desired compounds. The present invention can utilize a plurality of highly active compounds, with one embodiment being the use of chemotherapeutics for the treatment of cancer.

Abstract: A system which comprises a series of native applications, suited to run on mobile devices, and a series of web-based applications for which functionality and processing are optimized. The native applications and the web-based applications are coordinated to optimize processes of acquiring, storing and disseminating data for speed, integrity and security.

Abstract: A multi-functional, all inclusive smoking tool may include a housing; a cigarette lighter attached to the housing; a poker attached to the housing so that the poker can swivel outward from the housing and swivel inward towards the housing, while attached to the housing; and wherein the elongated poker is configured to be swiveled outwards from the housing and thereafter used to clean debris from pipes, while attached to the housing. The apparatus may further include a clip attached to the housing so that the clip is configured to be moved, while attached to the housing, from a first position to a second position, with respect to the housing; wherein in the first position, the clip is at least partially within the housing, while attached to the housing; and wherein in the second position, the clip is entirely outside of the housing, while attached to the housing.

Abstract: A system and method to correct for height error during a robotic welding additive manufacturing process. One or both of a welding output current and a wire feed speed are sampled during a robotic welding additive manufacturing process when creating a current weld layer. A plurality of instantaneous contact tip-to-work distances (CTWD's) are determined based on at least one or both of the welding output current and the wire feed speed. An average CTWD is determined based on the plurality of instantaneous CTWD's. A correction factor is generated, based on at least the average CTWD, which is used to compensate for any error in height of the current weld layer.

Abstract: A system includes one or more processors that are configured to obtain a constraint on movement for a first vehicle system along a route. The constraint is based on movement of a separate second vehicle system that is concurrently traveling along the same route. The processor(s) are configured to determine a speed profile that designates speeds for the first vehicle system according to at least one of distance, location, or time based on the constraint such that the first vehicle system maintains a designated spacing from the second vehicle system along the route.

Abstract: An optical encoder configuration comprises a cylindrical or planar rotary scale including yawed grating bars, an illumination source, a structured illumination generating arrangement (SIGA) and a detector arrangement including a photodetector. The SIGA is configured to input source light to a first illumination region on the rotary scale which diffracts light to a beam deflector configuration which transmits the diffracted light in a form that provides a particular fringe pattern proximate to a second illumination region on the scale. The scale filters and outputs that light to form a detector fringe pattern of intensity bands that are long along the rotary measuring direction and relatively narrow and periodic along a detected fringe motion direction (DFMD) transverse to the rotary measuring direction. The photodetector is configured to detect a position of the intensity bands as a function of rotary scale displacement and provide corresponding displacement or position signals.

Abstract: An instrument device manipulator (IDM) is attached to a surgical arm of a robotic system and comprises a surgical tool holder and an outer housing. The surgical tool holder includes an attachment interface that can secure a surgical tool in a front-mount configuration (where the attachment interface is on a face opposite of an elongated body of the surgical tool) or a back-mount configuration (where the attachment interface is on the same face as the elongated body of the surgical tool). The surgical tool holder may rotate continuously within the outer housing. In a back-mount configuration, the surgical tool holder may have a passage that receives the elongated body of the tool and allows free rotation of the elongated body about the rotational axis. A surgical drape separates the IDM and robotic arm from a tool, while allowing electrical and/or optical signals to pass therebetween.

Abstract: In one embodiment, an apparatus may comprise: a floor panel for a rotorcraft; one or more puck fasteners in the floor panel, wherein each puck fastener comprises an attachment fitting and a plurality of internal flanges, wherein the plurality of internal flanges within each puck fastener are adjacent; and one or more seating fixtures coupled to the floor panel using the one or more puck fasteners.

Abstract: A tool for repairing an out-of-round component such as a combustor body is disclosed. The tool includes a base including a first arcuate member; a second arcuate member; and a linear actuator coupling the second arcuate member to the base. The linear actuator moves the second arcuate member between a retracted position out of engagement with the out-of-round component and an extended position in which the first arcuate member and the second arcuate member engage an interior surface of the out-of-round component in an opposing relationship to force the out-of-round component into a more round state compared to an initial state of the out-of-round component. A related method is also disclosed.

Abstract: Embodiments of systems and methods to relate a human operator to a welding power source are disclosed. One embodiment is a networked system having a server computer. The server computer is configured to receive first data including at least one of an identity or a location of a welding helmet within a welding environment, and a triggering status indicating a triggering of an arc detection sensor of the welding helmet due to initiation of a welding arc. The server computer is configured to receive second data including at least one of an identity or a location of a welding power source within the welding environment, and an activation status indicating an activation of the welding power source. The server computer is configured to match the welding power source to a human operator using the welding helmet based on at least the first data and the second data.

Abstract: In one embodiment, an apparatus may comprise: a floor panel for a rotorcraft; one or more puck fasteners in the floor panel, wherein each puck fastener comprises an attachment fitting and a plurality of internal flanges, wherein the plurality of internal flanges within each puck fastener are adjacent; and one or more seating fixtures coupled to the floor panel using the one or more puck fasteners.

Abstract: A luminaire having a substantially two-piece housing with a first portion and a second portion, for example a cover and a base. The cover receives one or more control components. The base receives a light emitter assembly and the control component assembly is operatively connected to the lighter emitter assembly to control the light output therefrom. A lens assembly can be connected to the bottom of the base 14. Different mounting components can be connected to cover to connect the luminaire 10 to a support.