Patents by Inventor Joseph Brennan

Joseph Brennan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10328450
    Abstract: Method of designing and manufacturing a distributor bar for use in a production line comprising a mixing head for providing a viscous foamable liquid mixture, a laminator with a predefined speed of at least 20 m/min, the distributor bar having a central inlet fluidly connected to a number of outlets via a main channel. The method comprises: choosing (3001) a geometry for the distributor bar and defining a set of geometrical parameters; assigning (3002) values to said parameters; creating (3003) a virtual model; simulating (3005) flow in said model by performing a Computational Fluid Dynamics simulation (CFD), taking into account (3004) a non-Newtonian shear thinning model; e) evaluating the simulated flow; building (2007) a physical distributor bar. A distributor bar, a production line, and a computer program product.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: June 25, 2019
    Assignee: HUNTSMAN INTERNATIONAL LLC
    Inventor: Mark Joseph Brennan
  • Publication number: 20190026848
    Abstract: The systems and methods herein provide a user-friendly, automated and transparent, contract drafting and negotiation tool. Through the contract drafting and negotiation tool two parties can negotiate agreement using template agreements including one or more sections in which each user is able to select one of a plurality of input options that affect the terms of the contract. In each instance, each party can see the option selected by the other party, as well as the options not selected by the other party. The systems and methods facilitate efficient and transparent contract negotiation and drafting.
    Type: Application
    Filed: July 19, 2018
    Publication date: January 24, 2019
    Inventors: Michael Denker, Joseph Brennan
  • Publication number: 20180068123
    Abstract: A service for protecting the privacy of domain name registrants while preserving the registrant's ability to directly change the registration information or transfer the registration. A domain name registration is created that reflects the registrant's actual identity but contains contact information that is entirely associated with a privacy service.
    Type: Application
    Filed: October 16, 2017
    Publication date: March 8, 2018
    Inventor: Charles Joseph Brennan, III
  • Patent number: 9839648
    Abstract: A drug combination against acid-fast bacillus, including: an inhibitor for WecA or an ortholog thereof; and at least one of an inhibitor for MurX or an ortholog thereof and an RNA synthesis inhibitor, wherein the inhibitor for WecA or an ortholog thereof is used in combination with the at least one of an inhibitor for MurX or an ortholog thereof and an RNA synthesis inhibitor; a screening method for a drug against acid-fast bacillus; and an inhibitor for WecA or an ortholog thereof.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: December 12, 2017
    Assignees: MICROBIAL CHEMISTRY RESEARCH FOUNDATION, COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Yoshimasa Ishizaki, Masayuki Igarashi, Patrick Joseph Brennan, Dean Calvin Crick
  • Patent number: 9823261
    Abstract: A multi-well fluid container that includes a container body is provided for use in an in vitro diagnostics automation system. The container body includes a first well having a first well size configured to hold a first fluid and an openable first well closure that covers a first well opening. The first well opening provides access to the first fluid in the first well when the openable first well closure is opened. The container body also includes a second well having a second well size configured to hold a second fluid and having an openable second well closure that covers a second well opening. The second well opening provides access to the second fluid in the second well when the openable second well closure is opened. The first well size of the first well is different than the second well size of the second well.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: November 21, 2017
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Joseph Brennan, James Kegelman
  • Patent number: 9817979
    Abstract: A service for protecting the privacy of domain name registrants while preserving the registrant's ability to directly change the registration information or transfer the registration. A whois record is created that reflects the registrant's actual identity but contains contact information that is entirely associated with a privacy service.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: November 14, 2017
    Assignee: Network Solutions, LLC
    Inventor: Charles Joseph Brennan, III
  • Publication number: 20170285619
    Abstract: Method of designing and manufacturing a distributor bar for use in a production line comprising a mixing head for providing a viscous foamable liquid mixture, a laminator with a predefined speed of at least 20 m/min, the distributor bar having a central inlet fluidly connected to a number of outlets via a main channel. The method comprises: choosing (3001) a geometry for the distributor bar and defining a set of geometrical parameters; assigning (3002) values to said parameters; creating (3003) a virtual model; simulating (3005) flow in said model by performing a Computational Fluid Dynamics simulation (CFD), taking into account (3004) a non-Newtonian shear thinning model; e) evaluating the simulated flow; building (2007) a physical distributor bar. A distributor bar, a production line, and a computer program product.
    Type: Application
    Filed: August 24, 2015
    Publication date: October 5, 2017
    Inventor: Mark Joseph Brennan
  • Patent number: 9522177
    Abstract: The present invention relates to an antimicrobial and immunostimulatory system, applications thereof and a process for the production of the antimicrobial and immunostimulatory system. The present invention provides a storage-stable antimicrobial and immunostimulatory system comprising an oxidoreductase enzyme, a substrate for the oxidoreductase enzyme and hydrogen peroxide in an aqueous solution wherein the substrate for the oxidoreductase enzyme is present up to 90% by weight and water is present up to 20% by weight based on the weight of the total composition; the system has a pH from approximately 4 to 8; and the system provides a two-stage hydrogen peroxide release.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: December 20, 2016
    Assignee: INSTITUTE OF TECHNOLOGY SLIGO
    Inventors: John Reginald Barrett, James Joseph Brennan, Thomas Patrick Patton
  • Patent number: 9522165
    Abstract: The present invention relates to a formulation and method for the treatment of fungal nail infections, such as those caused by Trichophyton rubrum and/or Aspergillus niger. The formulation of the invention comprises glucose oxidase, D-glucose and hydrogen peroxide in an aqueous solution. Advantageously, the formulation of the invention provides a two-stage hydrogen peroxide release for the treatment of the fungal nail infections.
    Type: Grant
    Filed: January 2, 2013
    Date of Patent: December 20, 2016
    Assignee: Institute of Technology Sligo
    Inventors: John Reginald Barrett, James Joseph Brennan, Thomas Patrick Patton
  • Publication number: 20160362737
    Abstract: The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3?-OH blocking group covalently attached thereto, such that the 3? carbon atom has attached a group of the structure —O—Z wherein Z is any of —C(R?)2—O—R?, —C(R?)2-N(R?)2,—C(R?)2-N(H)R?, —C(R?)2-S—R? and —C(R?)2-F, wherein each R? is or is part of a removable protecting group; each R? is independently a hydrogen atom, an alkyl, substituted alkyl, arylalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclic, acyl, cyano, alkoxy, aryloxy, heteroaryloxy or amido group, or a detectable label attached through a linking group; or (R?)2 represents an alkylidene group of formula ?C(R??)2 wherein each R?? may be the same or different and is selected from the group comprising hydrogen and halogen atoms and alkyl groups; and wherein said molecule may be reacted to yield an intermediate in which each R? is exchanged for H or, where Z is —C(R?)2-F, the F is exc
    Type: Application
    Filed: June 10, 2016
    Publication date: December 15, 2016
    Inventors: John MILTON, Xiaolin WU, Mark SMITH, Joseph BRENNAN, Colin BARNES, Xiaohai LIU, Silke RUEDIGER
  • Patent number: 9517468
    Abstract: Disclosed are methods to aid in a calibration of a vertical orientation of a nozzle tip to a sample container in a processing or testing system. The method includes positioning the nozzle over a calibration target at a home height location (HM), moving the nozzle downward a distance (D) until contact with the calibration target is sensed, positioning the nozzle over the sample rack and moving the nozzle downward until contact with a registration location is sensed, imaging the sample rack and calibration target to determine a height (H) between the registration location and calibration target, and calculating a translation ratio (TR) between the height (H) measured in pixel space and the distance (D) measured in machine space. The translation ratio (TR) may be used to drive the nozzle tip to a predetermined depth. A robot calibration system is disclosed, as are other aspects.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: December 13, 2016
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Antoine E. Haddad, John Esposito, Joseph Brennan, John Mizzer
  • Publication number: 20160266155
    Abstract: A multi-well fluid container that includes a container body is provided for use in an in vitro diagnostics automation system. The container body includes a first well having a first well size configured to hold a first fluid and an openable first well closure that covers a first well opening. The first well opening provides access to the first fluid in the first well when the openable first well closure is opened. The container body also includes a second well having a second well size configured to hold a second fluid and having an openable second well closure that covers a second well opening. The second well opening provides access to the second fluid in the second well when the openable second well closure is opened. The first well size of the first well is different than the second well size of the second well.
    Type: Application
    Filed: October 30, 2014
    Publication date: September 15, 2016
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Joseph Brennan, James Kegelman
  • Publication number: 20160266156
    Abstract: An anti-evaporation tube for use with an in vitro diagnostics automation system is provided. The anti-evaporation tube includes an anti-evaporation tube body configured to be automatically inserted in a container and to limit evaporation of one or more fluids in the container and an alignment portion disposed on the anti-evaporation tube body. The alignment portion is configured to automatically align the anti-evaporation tube body within the container and cause the anti-evaporation tube body to remain aligned within the container. The alignment portion includes one or more openings disposed on an upper area of the anti-evaporation tube body. The one or more openings are configured to provide ventilation.
    Type: Application
    Filed: October 30, 2014
    Publication date: September 15, 2016
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Joseph Brennan, James Kegelman, William Hudson
  • Patent number: 9417255
    Abstract: An analyzer for use with in vitro diagnostics includes one or more containers. Each container includes a container body configured to hold one or more fluids, a closure device disposed on the container body and housing a movable cannula, and a sealing portion configured to seal off the one or more fluids in the container body from matter outside the container body when the sealing portion is closed. The system also includes one or more pick and place devices configured to move the one or more containers between different locations. The movable cannula is configured to move downward responsive to a force from the one or more pick and place devices and cause an opening in the sealing portion.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: August 16, 2016
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Joseph Brennan, James Kegelman
  • Patent number: 9393249
    Abstract: The present invention relates to an improved antimicrobial composition comprising a hydrogen peroxide source and one or more antimicrobial agents. Ideally, the invention relates to an antimicrobial composition comprising (i) hydrogen peroxide source and (ii) an antimicrobial agent and its associated use in therapy, particularly in the treatment of antimicrobial infections.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: July 19, 2016
    Assignee: INSTITUTE OF TECHNOLOGY SLIGO
    Inventors: John Reginald Barrett, James Joseph Brennan, Thomas Patrick Patton
  • Patent number: 9388464
    Abstract: The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3?-OH blocking group covalently attached thereto, such that the 3? carbon atom has attached a group of the structure —O—Z wherein Z is any of —C(R?)2-O—R?, —C(R?)2-N(R?)2, —C(R?)2-N(H)R?, —C(R?)2-S—R? and —C(R?)2-F, wherein each R? is or is part of a removable protecting group; each R? is independently a hydrogen atom, an alkyl, substituted alkyl, arylalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclic, acyl, cyano, alkoxy, aryloxy, heteroaryloxy or amido group, or a detectable label attached through a linking group; or (R?)2 represents an alkylidene group of formula ?C(R??)2 wherein each R?? may be the same or different and is selected from the group comprising hydrogen and halogen atoms and alkyl groups; and wherein said molecule may be reacted to yield an intermediate in which each R? is exchanged for H or, where Z is —C(R?)2-F, the F is ex
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: July 12, 2016
    Assignee: Illumina Cambridge Limited
    Inventors: John Milton, Xiaolin Wu, Mark Smith, Joseph Brennan, Colin Barnes, Xiaohai Liu, Silke Ruediger
  • Publication number: 20160129035
    Abstract: A drug combination against acid-fast bacillus, including: an inhibitor for WecA or an ortholog thereof; and at least one of an inhibitor for MurX or an ortholog thereof and an RNA synthesis inhibitor, wherein the inhibitor for WecA or an ortholog thereof is used in combination with the at least one of an inhibitor for MurX or an ortholog thereof and an RNA synthesis inhibitor; a screening method for a drug against acid-fast bacillus; and an inhibitor for WecA or an ortholog thereof.
    Type: Application
    Filed: June 3, 2014
    Publication date: May 12, 2016
    Inventors: Yoshimasa ISHIZAKI, Masayuki IGARASHI, Patrick Joseph BRENNAN, Dean Calvin CRICK
  • Publication number: 20160032378
    Abstract: The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3?-OH blocking group covalently attached thereto, such that the 3? carbon atom has attached a group of the structure —O—Z wherein Z is any of —C(R?)2-O—R?, —C(R?)2-N(R?)2, —C(R?)2-N(H)R?, —C(R?)2-S—R? and —C(R?)2-F, wherein each R? is or is part of a removable protecting group; each R? is independently a hydrogen atom, an alkyl, substituted alkyl, arylalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclic, acyl, cyano, alkoxy, aryloxy, heteroaryloxy or amido group, or a detectable label attached through a linking group; or (R?)2 represents an alkylidene group of formula ?C(R??)2 wherein each R?? may be the same or different and is selected from the group comprising hydrogen and halogen atoms and alkyl groups; and wherein said molecule may be reacted to yield an intermediate in which each R? is exchanged for H or, where Z is —C(R?)2-F, the F is ex
    Type: Application
    Filed: August 7, 2015
    Publication date: February 4, 2016
    Inventors: John MILTON, Xiaolin WU, Mark SMITH, Joseph BRENNAN, Colin BARNES, Xiaohai LIU, Silke RUEDIGER
  • Publication number: 20160016162
    Abstract: A fluid container includes a container body configured to hold one or more fluids. The container body has a first side wall and an opposing second side wall. The fluid container also includes one or more container alignment features disposed on an outer surface of the first side wall and configured to self-align the container body with a datum. The fluid container also includes one or more anti-evaporation tube alignment mechanisms disposed on one or more inner surfaces of the container body and configured to self-align an anti-evaporation tube within the container body.
    Type: Application
    Filed: February 27, 2014
    Publication date: January 21, 2016
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Joseph Brennan, James Kegelman, William Hudson, Peter Gebrian
  • Publication number: 20160003861
    Abstract: An analyzer for use with in vitro diagnostics includes one or more containers. Each container includes a container body configured to hold one or more fluids, a closure device disposed on the container body and housing a movable cannula, and a sealing portion configured to seal off the one or more fluids in the container body from matter outside the container body when the sealing portion is closed. The system also includes one or more pick and place devices configured to move the one or more containers between different locations. The movable cannula is configured to move downward responsive to a force from the one or more pick and place devices and cause an opening in the sealing portion.
    Type: Application
    Filed: February 19, 2014
    Publication date: January 7, 2016
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
    Inventors: Joseph Brennan, James Kegelman