Abstract: The invention refers to a handheld injection device comprising a housing (10; 410), a dose indicator (90; 480) positioned within and axially constrained to the housing (10; 410) and rotatable with respect to the housing (10; 410) during dose setting and during dose dispensing, a gauge element (80; 490), which is at least partly interposed between the housing (10; 410) and the dose indicator (90; 480), wherein the gauge element (80; 490) is axially guided within the housing (10; 410) and in threaded engagement with the dose indicator (90; 480) such that rotation of the dose indicator (90; 480) causes an axial displacement of the gauge element (80; 490). A contrast element having a first marking is provided and at least a region of the gauge element (80; 490) is provided with a second marking, with the first marking and/or the second marking being visible through a first window (12a) or aperture in the housing (10; 410) depending on the axial position of the gauge element (80; 490) within the housing (10; 410).

Abstract: The invention relates to an electronically controlled drug delivery device for administering a dose of a drug, comprising a body with a touchscreen and a control unit for controlling the touchscreen and operation of the drug delivery device related to delivery of the dose.

Abstract: Apparatuses and methods associated with management of computing infrastructure resources and workloads are disclosed herein. In embodiments, an apparatus may comprise a resource-workload manager having: a placement solution generator to generate a plurality of potential resource placement solutions for allocation of various resources of the computing infrastructure to various workloads; one or more utility function calculators to calculate one or more values for one or more provider-centric attributes, and one or more values for one or more customer-centric attributes, for the plurality of potential solutions; an analyzer to analyze the attributes and select one of the potential resource placement solutions; and a resource allocator to allocate the resources, based at least in part on the selected resource placement solution. Other embodiments may be described and/or claimed.

Abstract: The present invention relates to a dose setting mechanism for a drug delivery device and a method of using same. The mechanism comprises a housing, a mechanism member movable in a first axial direction relative to the housing during dose setting and movable in a second, opposite axial direction relative to the housing during injection, wherein the mechanism member is designed and arranged such that the mechanism member is able to change its condition between a first condition preventing movement in the second axial direction and a second condition allowing movement in the second axial direction, and a switching member forcing the mechanism member to change from its second condition into its first condition at a predefined position of the movement in the first axial direction during dose setting.

Abstract: A coding system for a drug reservoir, where the drug reservoir is intended for use with a reservoir holder of a drug delivery device. The coding system includes a collar fitted around the drug reservoir. The collar includes a coding feature that is configured to pass through a corresponding coding feature provided by the reservoir holder of the drug delivery device.

Abstract: A handheld injection device comprising a housing, a piston rod defining a first longitudinal axis and located within the housing, a driver coupled to the piston rod, a dose setting means, which is rotatable about a second longitudinal axis during dose setting, and optionally a power reservoir for driving the driver and/or a release clutch preventing rotation of the driver during dose setting and allowing rotation of the driver during dose dispensing. The first longitudinal axis is spaced from the second longitudinal axis.

Abstract: A coded cartridge holder for use with a drug delivery device is provided. The cartridge holder includes a fastener that becomes operative based in part on a length of a cartridge or a diameter of the cartridge. In one embodiment, the cartridge holder is coupled to the drug delivery device. The cartridge holder comprises a first blocking feature. The drug delivery device includes a cartridge detector comprising a second blocking feature. This feature may be a pin, for engagement with the first blocking feature of the cartridge holder when the cartridge acts on the cartridge detector. The cartridge holder may further include a fastening mechanism configured to fasten the cartridge holder to the drug delivery device only when the second blocking feature engages the first blocking feature.

Abstract: A system comprises a scoring engine comprising at least one processor and memory. The scoring engine is to generate, based on telemetry information obtained from a plurality of nodes of a computing infrastructure, a first availability score for a first node of the plurality of computing infrastructure nodes and a second availability score for a second node of the plurality of computing infrastructure nodes. The scoring engine is further to generate, based on the first availability score of the first computing infrastructure node and the second availability score of the second computing infrastructure node, an edge tension score for a link between the first node and the second node.

Abstract: A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with a track comprising a sequence of encoded images; and a sensor directed at the track of the cylindrical member and configured to detect features of the encoded images.

Abstract: Described is a needle assembly magazine comprising a housing including a coupling having a proximal aperture adapted to receive a medicament delivery device and a distal aperture adapted to receive a needle of a needle assembly, a needle guard coupled to the housing and having an aperture axially aligned with the distal aperture of the coupling, and a needle assembly carrier rotatably coupled to the needle guard and adapted to hold a plurality of needle assemblies. Rotation of the needle assembly carrier aligns one needle assembly with the distal aperture and the aperture.

Abstract: Methods, systems, and storage media for telemetry adaptation are disclosed herein. In an embodiment, a networking device may include a data collector agent module to receive measurement data from measurement sources according to an initial telemetry policy and to provide the measurement data to the one or more servers of the monitoring system. The networking device may include an anomaly detection module to receive measurement data from the data collector agent module, to detect an anomaly in the measurement data, and to provide an indication of the anomaly to the data collector agent module for the data collector agent module to provide a first modified telemetry policy for the measurement sources.

Abstract: A coded cartridge holder for use with a drug delivery device is provided. The cartridge holder includes a fastener that becomes operative based in part on a length of a cartridge or a diameter of the cartridge. In one embodiment, the cartridge holder is coupled to the drug delivery device. The cartridge holder comprises a first blocking feature. The drug delivery device includes a cartridge detector comprising a second blocking feature. This feature may be a pin, for engagement with the first blocking feature of the cartridge holder when the cartridge acts on the cartridge detector. The cartridge holder may further include a fastening mechanism configured to fasten the cartridge holder to the drug delivery device only when the second blocking feature engages the first blocking feature.

Abstract: A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a housing having an opening, a dose selector operable to set a dose by rotation relative to the housing, a release member controlling movement of a piston in a dispensing direction, and a display comprising a units number wheel and a tens number wheel which are coupled to each other such that a continuous rotation of the units number wheel is translated into an intermittent rotary motion of the tens number wheel. The release member rotates, during dose dispensing, an angle corresponding to the dose set by the dose selector, thereby allowing a piston to move in a dispensing direction.

Abstract: The disclosure is directed to a drive mechanism for use in a drug delivery device having a cartridge, the mechanism comprising a base element, a toothed piston rod movable from a first retracted position corresponding to a full cartridge to a second extended position corresponding to an empty cartridge, wherein the piston rod is guided within and movable relative to the base portion, and a drive gear having a pinion, which is rotatably held in the base element and in meshed engagement with the toothed piston rod, wherein the toothed piston rod comprises multiple rigid rod pieces which are connected by hinges, and a drive spring, which is fixed to the base element with one end and fixed to the drive gear with another end and which exerts a force or torque to the drive gear for rotating the drive gear relative to the base element, which rotation results in a movement of the toothed piston rod.

Abstract: A drug delivery device for selecting and dispensing a number of user variable doses of a medicament.

Abstract: The present disclosure relates to a drive mechanism which is suitable for an injection device, especially a pen type drug delivery device and to such a drug delivery device. The mechanism comprises a spring driven rotatable drive member, a rotatable driven member, a clutch rotationally coupling the driven member and the drive member in a coupled state and allowing relative clockwise and anti-clockwise rotation between the driven member and the drive member in a decoupled state, and a spring biasing the clutch into its coupled state and allowing relative axial movement between the drive member and the driven member into the decoupled state of the clutch against the bias of the spring.

Abstract: The present invention relates to a dispensing speed control mechanism for use in an injection device. The injection device may have a housing (10, 30, 40; 40?; 40?; 40??) and a drive member (70), which is driven by a power reservoir (100, 100?) and axially movable between a dose setting position, in which the drive member (70) is rotationally constrained to the housing (10, 30, 40; 40?; 40?; 40??), and a dose dispensing position, in which the drive member (70) is rotationally de-coupled from the housing (10, 30, 40; 40?; 40?; 40??). The speed control mechanism comprises friction means (42) for retarding the drive member (70) during dose dispensing depending on the axial position of the drive member (70). Further, the invention relates to an injection device with such a dispensing speed control mechanism.

Abstract: A drive mechanism of an injection device for setting and dispensing of a dose of a medicament includes a body accommodating a cartridge filled with a medicament, an insert axially displaceable inside the body between a proximal operating position and a distal reset position, a piston rod to operably engage with a piston of the cartridge, a drive sleeve rotationally coupled with the piston rod and is rotationally lockable to the body for setting of a dose and rotationally releasable from the body for dispensing of a dose, respectively. The drive sleeve is axially displaceable relative to the body from a proximal operating position into a distal reset position through an axial connection of the insert and the drive sleeve, where the drive sleeve is rotationally released from the body when in the distal reset position.

Abstract: Aspects of the present disclosure generally relate to systems and methods for managing and monitoring a plurality of emergency power supply systems (EPSS's) at a facility via an emergency power management system (EPMS). The EPMS generally comprises EPSS equipment, a management computer system for managing, monitoring, and testing the operational characteristics of the EPSS equipment, and a plurality of interface modules for providing unified communication capabilities between the management computer system and the EPSS equipment. Additional aspects relate to methods for easily and efficiently creating and installing an EPMS at a facility. Further aspects are directed to providing predictive analyzes related to the EPSS equipment. Also, aspects of the present disclosure relate to normalizing EPSS equipment information across varying vendors, makes, and models of equipment so as to provide a unified view of all equipment across a given facility.

Abstract: A dose setting mechanism for a drug delivery device is provided comprising a dose setting member and a further element. Maximum dose stop features are provided on a housing and on the further element.