Abstract: A dose setting mechanism for a drug delivery device is provided comprising a dose setting member and a further element. Maximum dose stop features are provided on a housing and on the further element.

Abstract: Techniques for dynamically adapting cloud applications are described. A current value of a Key Performance Indicator (KPI) of an executing cloud service instance of a cloud application is detected. A determination is made as to whether the current value of the KPI is unacceptable (e.g., either it is outside of an acceptable range or is within an adaptation region). If the current value of the KPI is unacceptable, a first application programming interface (API) is invoked to request a cloud service instance monitor to adapt the cloud service instance to operate within an acceptable KPI range. If the cloud service instance monitor was unsuccessful, the unacceptable KPI is escalated to the cloud service monitor for the type of the cloud service instance. If the cloud service monitor is unsuccessful, the unacceptable KPI is escalated to the application monitor.

Abstract: A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with a track comprising a sequence of encoded images; and a sensor directed at the track of the cylindrical member and configured to detect features of the encoded images.

Abstract: Examples are described for computing resource discovery and management for a system of configurable computing resources that may include disaggregate physical elements such as central processing units, storage devices, memory devices, network input/output devices or network switches. In some examples, these disaggregate physical elements may be located within one or more racks of a data center.

Abstract: A cartridge assembly (200) having a shared fastening features for use with a drug delivery device (202). The cartridge assembly includes a cartridge holder (204), a drug cartridge (206), and a connector (208). The connector may be attached to the drug cartridge. The cartridge assembly further includes a fastening means (210, 212) for fastening to a drug delivery device, and this fastening means is shared between the cartridge holder and the cartridge or between the cartridge holder and the connector. The drug delivery device may be a reusable drug delivery device or a disposable drug delivery device.

Abstract: A dispense mechanism for a drug delivery device for the delivery of a primary medicament in a primary cartridge and a secondary medicament in a secondary cartridge includes a primary drive member and a secondary drive member serve for driving a primary and a secondary lead screw. The primary drive member and the secondary drive member are configured to rotate during dose dispense. A coupling member serves for rotationally coupling the primary drive member to the secondary drive member and moves from a first position in which the primary drive member is rotationally decoupled from the secondary drive member into a second position in which the primary drive member is rotationally coupled to the secondary drive member during dose dispense. Rotation of the primary drive member moves the coupling member from the first position into the second position.

Abstract: In one embodiment, a system comprises a scoring engine comprising at least one processor and memory. The scoring engine is to generate, based on telemetry information obtained from a plurality of nodes of a computing infrastructure, a first availability score for a first node of the plurality of computing infrastructure nodes and a second availability score for a second node of the plurality of computing infrastructure nodes. The scoring engine is further to generate, based on the first availability score of the first computing infrastructure node and the second availability score of the second computing infrastructure node, an edge tension score for a link between the first node and the second node.

Abstract: A sprayhead for use with an aerosol container, the sprayhead including a chassis capable of firm attachment to the container; a rotatable circular collar; a spray channel and associated actuator button; and an over-cap; the rotatable circular collar being rotatable between a first and second position, wherein, when the rotatable circular collar is in the first position, a holding feature of the rotatable circular collar interacts with a holding feature of the chassis and wherein the rotatable circular collar further includes a projection that interacts with a non-rotating feature of the overcap to produce an audible signal when the rotatable circular collar is rotated between its first and second position.

Abstract: Aspects of the present disclosure generally relate to systems and methods for managing and monitoring a plurality of emergency power supply systems (EPSS's) at a facility via an emergency power management system (EPMS). The EPMS generally comprises EPSS equipment, a management computer system for managing, monitoring, and testing the operational characteristics of the EPSS equipment, and a plurality of interface modules for providing unified communication capabilities between the management computer system and the EPSS equipment. Additional aspects relate to methods for easily and efficiently creating and installing an EPMS at a facility. Further aspects are directed to providing predictive analyzes related to the EPSS equipment. Also, aspects of the present disclosure relate to normalizing EPSS equipment information across varying vendors, makes, and models of equipment so as to provide a unified view of all equipment across a given facility.

Abstract: The present invention relates to a dose setting mechanism for a drug delivery device and a method of using same. The mechanism comprises a drug delivery device housing, a dose dial sleeve positioned at least partly in the housing and being rotatable during dose setting and dose delivery, a clutch rotatable during dose setting and non-rotatable during dose delivery, and a clutch nut, that is threadedly engaged with the clutch and is splined to the housing to prevent rotation of the clutch nut.

Abstract: A dose setting mechanism for a drug delivery device includes a primary drug delivery assembly and a secondary drug delivery assembly. The dose setting mechanism includes a primary dose dial component for setting a dose in the primary drug delivery assembly and a secondary dose dial component for setting a dose in the secondary drug delivery assembly. The primary dose dial component and the secondary dose dial component are configured to rotate during dose setting. A gear mechanism is configured such that in a first phase of the dose setting, rotation of the primary dose dial component is transferred to the secondary dose dial component and such that in a second phase of the dose setting, the secondary dose dial component is decoupled from the primary dose dial component such that rotation of the primary dose dial component is prevented from being transferred to the secondary dose dial component.

Abstract: Methods, systems, and storage media for telemetry adaptation are disclosed herein. In an embodiment, a networking device may include a data collector agent module to receive measurement data from measurement sources according to an initial telemetry policy and to provide the measurement data to the one or more servers of the monitoring system. The networking device may include an anomaly detection module to receive measurement data from the data collector agent module, to detect an anomaly in the measurement data, and to provide an indication of the anomaly to the data collector agent module for the data collector agent module to provide a first modified telemetry policy for the measurement sources.

Abstract: Examples include techniques to generate workload performance fingerprints for cloud infrastructure elements. In some examples, performance metrics are obtained from resource elements or nodes included in an identified sub-graph that represents at least a portion of configurable computing resources of a cloud infrastructure. For these examples, averages for the performance metrics are determined and then stored at a top-level context information node for the identified sub-graph to represent a workload performance fingerprint for the identified sub-graph.

Abstract: The invention is directed to drug delivery device comprising a primary drug delivery assembly (3) with a primary dose dial sleeve (17) and a secondary drug delivery assembly (4) with a secondary drive sleeve (24). For user selection, a selection switch (48) is movable between a first, a second and a third position and a clutch (49) is connected to the selection switch (48) such that movement of the selection switch (48) causes rotation of the clutch (49). A secondary drive sleeve (24) is configured to rotate and to engage the clutch (49), wherein the clutch (49) is configured to transfer rotation to the secondary drive sleeve (24) when the selection switch (48) is moved from the first position into the second position and to disengage from the secondary drive sleeve (24) when the selection switch (48) is moved from the first into the third position.

Abstract: The present invention is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament comprising a clicker arrangement. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) coupled to the dose selector (80) and arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), a piston rod (30) coupled to the housing (10) and to a drive sleeve (40) such that rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10), a clutch (120) arranged between the number sleeve (60) and the drive sleeve (40), and a dispense clicker comprising a flexible arm (123) and a toothed profile (75). The device further comprises a button (70) operable to effect dose dispensing.

Abstract: The present disclosure is directed to a spring arrangement for use in a drug delivery device and a drug delivery device including such a spring arrangement. The spring arrangement includes a clutch spring which is located axially interposed between a stationary housing component and an axially movable sleeve. The sleeve includes clutch features adapted to engage corresponding clutch features of a clutch element. The clutch spring biases the clutch features and the corresponding clutch features into engagement. The sleeve is coupled to a button such that upon actuation of the button the sleeve is translated against the bias of the clutch spring from a proximal position in which the sleeve is rotationally locked to the housing component into a distal position in which the sleeve is rotationally un-locked from the housing component. Upon release of the button the clutch spring translates the sleeve and the button into the proximal position.

Abstract: The present invention is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), a piston rod (30) coupled to the housing (10) and to a drive sleeve (40) such that rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10) and a clutch mechanism arranged between the number sleeve (60) and the drive sleeve (40).

Abstract: The invention is directed to a differential gear mechanism (26) for a drug delivery device with a primary drug delivery assembly (3) and a secondary drug delivery assembly (4), wherein the primary drug delivery assembly (3) comprises a primary dose dial sleeve (17) and wherein the secondary drug delivery assembly (4) comprises a secondary drive sleeve (24). The invention is also directed to a respective drug delivery device.

Abstract: A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with at least first and second tracks together forming an encoder, each track comprising conductive segments and non-conductive segments; and at least first and second groups of contacts configured to engage the first and second tracks respectively at predetermined intervals along the length of the track.

Abstract: The present invention is generally directed to an injection device for selecting and dispensing a number of user variable doses of a medicament.