Patents by Inventor Joseph C. Salamone

Joseph C. Salamone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modification of surfaces of polymeric articles by Michael addition reaction
    Publication number: 20080003259
    Abstract: A medical device having an increased surface hydrophilicity comprises a coating polymer comprising units of a polymerizable hydrophilic compound that is attached to the surface of the medical device via the Michael addition reaction. The coating polymer can be applied to a medical device comprising a hydrogel material. The attachment of the coating polymer may be enhanced by increasing the population of the medical-device surface functional groups before contacting the medical device with the coating polymer.
    Type: Application
    Filed: June 30, 2006
    Publication date: January 3, 2008
    Inventors: Joseph C. Salamone, Yu-Chin Lai, Weihong Lang, Wenyan Yan
  • Carboxylic tris-like siloxanyl monomers
    Publication number: 20080000201
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain carboxylic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerized carboxylic hydrophilic siloxanyl monomers.
    Type: Application
    Filed: June 30, 2006
    Publication date: January 3, 2008
    Inventors: Derek Schorzman, Jay Kunzler, Joseph C. Salamone
  • Carboxylic M2Dx-like siloxanyl monomers
    Publication number: 20080004413
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain carboxylic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerized carboxylic hydrophilic siloxanyl monomers.
    Type: Application
    Filed: June 30, 2006
    Publication date: January 3, 2008
    Inventors: Derek Schorzman, Jay Kunzler, Joseph C. Salamone
  • Ophthalmic Compositions Comprising A Branched, Glycerol Compound
    Publication number: 20070287752
    Abstract: An aqueous ophthalmic composition comprising a branched glycerol compound selected from the group consisting of a branched, glycerol monoalkyl ether, a branched, glycerol monoalkyl amine, a branched, glycerol monoalkyl sulfide, or any mixture thereof, present in a total amount of from 0.05 ppm to 1,000 ppm; a cationic antimicrobial component, and having an osmolality in a range from 200 mOsmol/kg to 400 mOsmol/kg. The presence of the branched glycerol compound enhances the biocidal efficacy of the aqueous ophthalmic composition containing one or more cationic antimicrobial components.
    Type: Application
    Filed: March 27, 2007
    Publication date: December 13, 2007
    Inventors: Susan E. Burke, Joseph C. Salamone
  • Ophthalmic Compositions Comprising a Branched, Glycerol Monoalkyl Compound and a Fatty Acid Monoester
    Publication number: 20070286767
    Abstract: An aqueous ophthalmic composition comprising a branched, glycerol monoalkyl compound and a fatty acid monoester. The fatty acid monoester comprises an aliphatic fatty acid portion having six to fourteen carbon atoms and an aliphatic hydroxyl portion. The composition will also have an osmolality in a range from 200 mOsmol/kg to 400 mOsmol/kg. The invention is also directed to a method of inhibiting the formation of foam in an aqueous ophthalmic composition that includes a surfactant as well as to a method of enhancing the biocidal efficacy of an aqueous ophthalmic composition containing a fatty acid monoester.
    Type: Application
    Filed: March 26, 2007
    Publication date: December 13, 2007
    Inventors: Susan E. Burke, Eric Phillips, Fang Zhao, Vicki Barniak, Joseph C. Salamone
  • High refractive-index, hydrophilic, arylsiloxy-containing macromonomers and polymers, and ophthalmic devices comprising such polymers
    Patent number: 7297160
    Abstract: Hydrophilic, arylsiloxy-containing macromonomers have at least a terminal hydrophilic group attached to an arylsiloxy group. The aryl groups attached to siloxy groups can be substituted with other hydrophilic groups. Polymers comprising such hydrophilic, arylsiloxy-containing macromonomers avoid or reduce the risk of forming vacuoles of absorbed water. Furthermore, such polymers have high refractive index, and, thus, are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: November 20, 2007
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark
  • Composition and method for cleaning lipid deposits on contact lenses
    Patent number: 7282178
    Abstract: This invention is directed to an aqueous composition and methods for clean lipid deposits on contact lenses. In particular, a combination of non-ionic surfactants, branched and/or straight poly(ethylene oxide-propylene oxide) (PEO-PPO) block copolymers having HLB value greater than or equal to 18, with an additional straight poly(ethylene oxide-propylene oxide) (PEO-PPO) block copolymers having HLB value less than or equal to 15, has been found to improve the lipid cleaning properties of an aqueous composition for contact lenses and prevent the overgrowth of harmful bacteria, yeast and molds without adversely affecting the comfort or safety in terms of the level of toxicity to eye tissue.
    Type: Grant
    Filed: May 30, 2006
    Date of Patent: October 16, 2007
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Roya Borazjani, Vicki Barniak, Robert Manchester, David McCanna
  • Vitreoretinal silicone tamponades made by supercritical fluid extraction
    Patent number: 7276619
    Abstract: A process for the purification of a silicone oil or fluid using neat supercritical carbon dioxide or a supercritical carbon dioxide mixture extraction to produce vitreoretinal silicone tamponades. The subject process is an economical, highly effective, reproducible, contaminant-free method by which unreacted relatively low molecular weight cyclic siloxanes and oligomers are removed from relatively high molecular weight silicone oil or fluid.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: October 2, 2007
    Assignee: Bausch & Lomb Incorporated
    Inventors: Jay F. Kunzler, Joseph C. Salamone, Dharmendra Jani, Erik M. Indra
  • Surface modification of functional group-containing medical devices with catalyst-containing reactive polymer system
    Patent number: 7270678
    Abstract: Surface modified medical devices such as intraocular lens implants formed from one or more functional group-containing materials using reactive, hydrophilic polymers with catalyst functionality for the purpose of reducing or eliminating lens epithelial cell growth thereon, reducing or eliminating silicone oil absorption upon subsequent surgical exposure and/or reducing implantation inserter friction is provided herein. Additionally, a method of making and using surface modified intraocular lens implants is provided.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: September 18, 2007
    Assignee: Bausch & Lomb Incorporated
    Inventors: Paul L. Valint, Jr., Joseph A. McGee, Joseph C. Salamone
  • Method and composition for reducing contact lens swelling
    Patent number: 7247270
    Abstract: The present invention is directed to an ophthalmic solution for soft contact lenses for controlled release of polyethers into an eye's tear film. Polyether components of the subject solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved end-of-the-day comfort and reduced feeling of dryness from wearing contact lenses. The present invention also includes the use of cationic polyelectrolytes for controlling the swelling of hydrogel contact lenses typically caused by the absorption of high concentrations of polyethers.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: July 24, 2007
    Assignee: Bausch & Lomb Incorporated
    Inventors: Zhenze Hu, Joseph C. Salamone, Dharmendra Jani
  • SILOXANE PREPOLYMER CONTAINING PENDANT AND END-CAPPING CATIONIC AND POLYMERIZABLE GROUPS
    Publication number: 20070160649
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic random copolymers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise siloxane prepolymer containing pendant and end-capping cationic and polymerizable groups.
    Type: Application
    Filed: November 30, 2006
    Publication date: July 12, 2007
    Inventors: Derek A. Schorzman, Joseph C. Salamone, Jay F. Kunzler
  • PROCESS FOR MAKING CATIONIC HYDROPHILIC SILOXANYL MONOMERS
    Publication number: 20070161810
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymeric compositions comprise polymerized cationic hydrophilic siloxanyl monomers prepared by the process disclosed herein.
    Type: Application
    Filed: December 15, 2006
    Publication date: July 12, 2007
    Inventors: Derek A. Schorzman, Joseph C. Salamone, Daniel M. Ammon
  • SILOXANE PREPOLYMER CONTAINING PENDANT CATIONIC AND POLYMERIZABLE GROUPS
    Publication number: 20070160643
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic random copolymers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise polymerized siloxane prepolymer containing pendant cationic and polymerizable groups.
    Type: Application
    Filed: December 15, 2006
    Publication date: July 12, 2007
    Inventors: Derek A. Schorzman, Joseph C. Salamone, Jay F. Kunzler
  • Use of aroma compounds as defoaming agents for ophthalmic solutions with high concentrations of surfactants
    Publication number: 20070148099
    Abstract: A method of reducing foam formation and improving odor in ophthalmic solutions, such as multipurpose cleaning and conditioning solutions and contact lens packing solutions. The ophthalmic solutions contain surfactant and aroma compound in an amount effective to decrease foam formation. The aroma compound has a low molecular weight and pleasing smell.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 28, 2007
    Inventors: Susan E. Burke, Daniel M. Ammon, Roya N. Borazjani, Joseph C. Salamone, Erning Xia
  • ANTIMICROBIAL OPHTHALMIC TREATMENT SYSTEM AND METHOD
    Publication number: 20070148127
    Abstract: An ophthalmic treatment system comprises an ophthalmic treatment solution and a biguanide antimicrobial agent in solid form and in contact with said treatment solution such as to inhibit bacterial and/or fungal growth in said solution. The biguanide is partially or wholly terminated with an amine compound.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 28, 2007
    Inventors: David J. Heiler, Joseph C. Salamone, Richard V. Smerbeck, Matthew S. Jonasse
  • High refractive index polymeric siloxysilane compositions
    Patent number: 7169874
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.
    Type: Grant
    Filed: November 2, 2001
    Date of Patent: January 30, 2007
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index polymeric siloxysilane compositions
    Patent number: 7138440
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: November 21, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index aromatic-based silyl monomers
    Patent number: 7132494
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: November 7, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye, David P. Vanderbilt
  • High refractive index polymeric siloxysilane compositions
    Patent number: 7101949
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: September 5, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index polymeric siloxysilane compositions
    Patent number: 7091299
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: August 15, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye