Patents by Inventor Joseph C. Salamone

Joseph C. Salamone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for enhancing integrity of epithelium using retinoic acid
    Patent number: 7087222
    Abstract: A method for improving the integrity of the corneal epithelium by introducing into the eye an effective amount of a ophthalmically compatible retinoid sufficient to enhance the integrity of the corneal epithelium.
    Type: Grant
    Filed: June 16, 2004
    Date of Patent: August 8, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Andrea M. Lever, Richard V. Smerbeck, O. William Lever, Jr., Joseph C. Salamone
  • Surface modification of functional group-containing intraocular lenses
    Patent number: 7083646
    Abstract: Surface modified medical devices such as intraocular lens implants formed from one or more functional group-containing materials using reactive, hydrophilic polymers for the purpose of reducing or eliminating lens epithelial cell growth thereon, reducing or eliminating silicone oil absorption upon subsequent surgical exposure and/or reducing or eliminating implantation inserter friction is provided herein. Additionally, a method of making and using surface modified intraocular lens implants is provided.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: August 1, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Paul L. Valint, Jr., Joseph A. McGee, Wenyan Yan, Joseph C. Salamone, Daniel M. Ammon, Jr., Jay F. Kunzler
  • Compositions with enhanced antimicrobial efficacy against
    Patent number: 7067479
    Abstract: Ophthalmic compositions include a polycation material to enhance antimicrobial efficacy against bacteria such as E. coli. The compositions include eye drop and contact lens treating solutions. A preferred polycation material is cationic cellulose derivatives.
    Type: Grant
    Filed: April 30, 2003
    Date of Patent: June 27, 2006
    Assignee: Bausch & Lomb Inc.
    Inventors: Erning Xia, Joseph C. Salamone, Roya Borazjani, Alyce K. Dobie, Deborah McGrath, Zhenze Hu, Daniel M. Ammon, Jr.
  • Method and composition for reducing contact lens swelling
    Patent number: 7037469
    Abstract: The present invention is directed to an ophthalmic solution for soft contact lenses for controlled release of polyethers into an eye's tear film. Polyether components of the subject solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved end-of-the-day comfort and reduced feeling of dryness from wearing contact lenses. The present invention also includes the use of cationic polyelectrolytes for controlling the swelling of hydrogel contact lenses typically caused by the absorption of high concentrations of polyethers.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: May 2, 2006
    Assignee: Bausch & Lomb, Inc.
    Inventors: Zhenze Hu, Joseph C. Salamone, Dharmendra Jani
  • High refractive index aromatic-based siloxane difunctional macromonomers
    Patent number: 7022749
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: April 4, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index aromatic-based siloxane difunctional macromonomers
    Patent number: 7009023
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: March 7, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index aromatic-based siloxane difunctional macromonomers
    Patent number: 7009024
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: March 7, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index aromatic-based siloxane monofunctional macromonomers
    Patent number: 7005494
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: February 28, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index aromatic-based siloxane monofunctional macromonomers
    Patent number: 6992162
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: January 31, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index aromatic-based siloxane monofunctional macromonomers
    Patent number: 6989430
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: January 24, 2006
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler
  • Surface treatment of medical device
    Patent number: 6958169
    Abstract: A method for improving the wettability of a medical device involves: (a) providing a medical device formed from a monomer mixture comprising a hydrophilic device-forming monomer including a copolymerizable group and an electron donating moiety, and a second device-forming monomer including a copolymerizable group and a reactive functional group; and (b) contacting a surface of the medical device with a wetting agent including a proton donating moiety reactive with the functional group provided by the second lens-forming monomer and that complexes with the electron donating moiety provided by the hydrophilic lens-forming monomer.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: October 25, 2005
    Assignee: Bausch & Lomb Incorporated
    Inventors: Jay F. Künzler, Joseph A. McGee, Joseph C. Salamone, David E. Seelye
  • High refractive index polymeric siloxysilane compositions
    Patent number: 6908978
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.
    Type: Grant
    Filed: November 2, 2001
    Date of Patent: June 21, 2005
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index aromatic-based siloxane monofunctional macromonomers
    Patent number: 6906162
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: June 14, 2005
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index aromatic-based siloxane difunctional macromonomers
    Patent number: 6881808
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: April 19, 2005
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index aromatic-based silyl monomers
    Patent number: 6881809
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: April 19, 2005
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye, David P. Vanderbilt
  • Method for in-eye cleaning of contact lens comprising polymeric beads
    Patent number: 6872695
    Abstract: An in-eye method for cleaning contact lenses comprises use of a cleaner using water-containing beads. The water-containing beads are prepared such that the bead size is smaller than the punctual opening. They are easily flushed from the ocular environment by normal tear flow. The cleaner may also be used to clean contact lenses, with the cleaner applied directly to the lens and digitally rubbed to remove accumulated debris on the lens.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: March 29, 2005
    Assignee: Bausch & Lomb Incorporated
    Inventors: Suzanne F. Groemminger, Joseph C. Salamone
  • Low water content, high refractive index, flexible, polymeric compositions
    Patent number: 6852793
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more copolymers with one or more hydrophilic monomers and optionally one or more aromatic-based monomers, hydrophobic monomers or a combination thereof.
    Type: Grant
    Filed: June 19, 2002
    Date of Patent: February 8, 2005
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
  • High refractive index aromatic-based silyl monomers
    Patent number: 6846897
    Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: January 25, 2005
    Assignee: Bausch and Lomb, Inc.
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye, David P. Vanderbilt
  • Prevention of preservative uptake into biomaterials
    Publication number: 20040258558
    Abstract: A method for inhibiting the ability of a biomaterial to sorb cationic antimicrobials comprising treating the surface of said biomaterial with a cationic polysaccharide.
    Type: Application
    Filed: July 14, 2004
    Publication date: December 23, 2004
    Inventors: Joseph C. Salamone, Daniel M. Ammon, Zhenze Hu
  • Rate controlled release of a pharmaceutical agent in a biodegradable device
    Publication number: 20040253293
    Abstract: Chemical erosion controlled release drug delivery systems are provided that allow controlled release of sustained concentrations of therapeutic agents within a treated area for a prolonged period of time. The favorable solubility characteristics of the chemical erosion controlled release drug delivery systems are controlled through the hydrophobicity and load level of pharmaceutically active agent or drug. Such controlled solubility characteristics allow for manipulation of the drug release rates depending on the particular therapeutic use and the particular needs of the patient.
    Type: Application
    Filed: June 16, 2003
    Publication date: December 16, 2004
    Inventors: Afshin Shafiee, Joseph C. Salamone, Dharmendra Jani, Stephen Paul Bartels, Jay F. Kunzler