Abstract: Disclosed herein are compositions, methods and kits useful for epigenetic analysis based on the use of transposons that are targeted to specific regions of chromatin based on DNA-DNA interactions, protein-protein interactions, RNA-RNA interactions, and nucleic acid-protein interactions.

Abstract: An apparatus includes a lead frame paddle configured for mounting a semiconductor die. The apparatus further includes a plating area formed on the lead frame paddle. The plating area is configured to receive a down bond from a semiconductor die placed on the lead frame paddle. The apparatus further includes an exposed gap between an outer edge of the plating area and an outer edge of the lead frame paddle.

Abstract: In accordance with various embodiments, described herein are systems and methods for use of computer-implemented machine learning to automatically determine insights of facts, segments, outliers, or other information associated with a set of data, for use in generating visualizations of the data. In accordance with an embodiment, the system can use a machine learning process to automatically determine one or more outliers or findings within the data, based on, for example, determining a plurality of combinations representing pairs of attribute dimensions within a data set, from which a general explanation or pattern can be determined for one or more attributes, and then comparing particular values for attributes, with the determined pattern for those attributes. Information describing such outliers or findings can be graphically displayed at a user interface, as text, graphs, charts, or other types of visualizations, and used as a starting point for further analysis of the data set.

Abstract: A query optimization system is described that, at runtime, optimizes the execution pipeline generated for a query. Based upon communications between nodes in the execution pipeline, the execution pipeline generated for a query is optimized by modifying the execution pipeline to create a modified execution pipeline. The modified execution pipeline is then executed to execute the query and results obtained for the query. The changes or modifications made to an execution pipeline may include changing the capabilities (e.g., changes to inputs and/or outputs of a node, changing the task(s) or function(s) performed by the node) of one or more nodes within the execution pipeline. The changes may include changing the position of one or more nodes within a directed acyclic graph representing the execution pipeline.

Abstract: Optimized techniques are disclosed for sorting variable-length records using an optimized amount of memory while maintaining good locality of references. The amount of memory required for sorting the variable length records is optimized by reusing some of the memory used for storing the variable length records being sorted. Pairs of input runs storing variable length records may be merged into a merged run that contains the records in a sorted order by incrementally scanning, sorting, and copying the records from the two input runs being merged into memory pages of the merged run. When all the records of a memory page of an input run have been processed or copied to the merged run, that memory page can be emptied and released to a cache of empty memory pages. Memory pages available from the cache of empty memory pages can then be used for generating the merged run.

Abstract: Techniques are described that enable the dynamic and automatic life cycle management of database schemas. Temporary database schemas are dynamically and automatically allocated in response to database schema requests. Allocated schemas are also automatically reclaimed upon expiration. A dynamic schema allocation system is provided that is configured to receive database schema requests from one or more clients and dynamically and automatically, substantially free of any manual intervention, serve database schemas in response to the requests. The database schemas may be allocated from multiple database instances available to the dynamic schema allocation system. Attributes specified in a database schema request may be used to find a matching database instance and a schema is allocated for the request from the matching database instance.

Abstract: The present invention provides an air driven dental handpiece device with a back end configured to receive an air and water supply; a handpiece body having an air intake tube and a water line tube carrying air and water respectively through the device; and a head receiving air to power the device's dental spindle. The head securely blocks air from leaking and returns the air through a large air return exhaust port back through the inside of the body and out a rear air exhaust assembly including a plurality of exhaust air holes and/or an air return exhaust port. The device helps eliminate a patient's sensitivity and discomfort, helps eliminate the risk of surgical air emphysema, as well as helps eliminate any cross contamination during oral surgical procedures.

Abstract: The invention provides novel methods and materials for genetic and genomic analysis using single or multiplex isolation of protein-associated nucleic acids, including transposase-assisted chromatin immunoprecipitation (TAM-ChIP) and antibody-oligonucleotide proximity ligation. These methods comprise tagging and isolating chromatin or other protein-associated nucleic acids and using antibody-oligonucleotide complexes that recognize the proteins associated with such nucleic acids.

Abstract: Disclosed herein are compositions, methods and kits useful for epigenetic analysis based on the use of transposons that are targeted to specific regions of chromatin based on DNA-DNA interactions, protein-protein interactions, RNA-RNA interactions, and nucleic acid-protein interactions.

Abstract: In an example detection system for vehicles or other objects of interest, objects are detected in real-time at full VGA 30 frame per second resolution. A preprocessor may perform run-length encoding (RLE) to provide detected edges. The image may then be scanned from the bottom up to identify vertical clusters or “stacks” or RLEs. Vertical clusters with low vertical density may be eliminated as poor vehicle candidates. Vertical clusters not eliminated may then be processed with a histogram of gradients algorithm, and confirmed with a support vector machine algorithm. A range to the nearest object may also be calculated, and a warning provided if the object is too close.

Abstract: Objects are detected in real-time at full VGA 30 frame per second resolution. A preprocessor performs run-length encoding (RLE) and generates a summed area table (SAT) of an image. The RLE and SAT are used to identify candidate objects and to iteratively refine their boundaries. A histogram of gradients (HoG) and support vector machine (SVM) then reliably classify the object. The method may be part of an advanced driver assistance system (ADAS).

Abstract: In an example detection system for vehicles or other objects of interest, objects are detected in real-time at full VGA 30 frame per second resolution. A preprocessor may perform run-length encoding (RLE) to provide detected edges. The image may then be scanned from the bottom up to identify vertical clusters or “stacks” or RLEs. Vertical clusters with low vertical density may be eliminated as poor vehicle candidates. Vertical clusters not eliminated may then be processed with a histogram of gradients algorithm, and confirmed with a support vector machine algorithm. A range to the nearest object may also be calculated, and a warning provided if the object is too close.

Abstract: The system relates to a system and apparatus for a scalable engineering system deployed in production that mines topical interests from multiple social networks and assigns over tens of thousands of topics to hundreds of millions of users on a daily basis. The system extracts and analyzes features for topic inference that extend beyond authored text. The system uses a diverse set of features and cross network information can lead to a better understanding of a user's interests. This system focuses on assigning topics for a user that other users can socially recognize and acknowledge.

Abstract: Disclosed herein are compositions, methods and kits useful for epigenetic analysis based on the use of transposons that are targeted to specific regions of chromatin based on DNA-DNA interactions, protein-protein interactions, RNA-RNA interactions, and nucleic acid-protein interactions.

Abstract: Techniques for utilizing different versions of a same font when rendering subsequent portions of a content item. For instance, envision that a user requests to open an electronic book. In response to this request, a display controller may display the first page of the electronic book using a flashing update and, therefore, may display the text using a regular weight of a particular font. However, when the user subsequently requests to turn to the second page of the electronic book, the display controller (utilizing a non-flashing update) may update the display using a version of the same font having a lesser weight. Given that some level of bleeding with likely occur when using the non-flashing update, the lesser weight coupled with the bleeding may result in text that approximates the weight of the text of the first page of the electronic book.

Abstract: The invention provides novel methods and materials for genetic and genomic analysis using single or multiplex isolation of protein-associated nucleic acids, including transposase-assisted chromatin immunoprecipitation (TAM-ChIP) and antibody-oligonucleotide proximity ligation. These methods comprise tagging and isolating chromatin or other protein-associated nucleic acids and using antibody-oligonucleotide complexes that recognize the proteins associated with such nucleic acids.

Abstract: A system and method for providing dynamic channel equalization in V2V and V2I communications systems. The method includes separating the channel bandwidth of a message into a plurality of subcarriers having different subcarrier frequencies, where the subcarriers include data subcarriers and pilot subcarriers. The method demodulates the message in the receiver to extract symbols from the message and determines channel estimation frequency responses using a least-squares estimation process and the extracted symbols for the pilot subcarriers. The channel estimation frequency responses of either the pilot subcarriers, the pilot subcarriers and some data subcarriers, or the pilot subcarriers and all data subcarriers are used to generate updated channel estimation frequency responses, and a new channel estimation frequency response is generated for each extracted signal using a previous channel estimation frequency response and the updated channel estimation frequency response.

Abstract: The present invention provides a method of covalently joining a DNA strand to an RNA strand, a method of tagging a 5? end of an RNA molecule, a DNA-RNA molecule which has been joined in vitro by the use of a topoisomerase, a method of tagging a 5? end of an mRNA, and a method of isolating and cloning full-length gene sequences using capped mRNA after subtraction of non-capped RNA.

Abstract: The present invention provides a method of covalently joining a DNA strand to an RNA strand, a method of tagging a 5? end of an RNA molecule, a DNA-RNA molecule which has been joined in vitro by the use of a topoisomerase, a method of tagging a 5? end of an mRNA, and a method of isolating and cloning full-length gene sequences using capped mRNA after subtraction of non-capped RNA.

Abstract: A system and method for providing dynamic channel equalization in V2V and V2I communications systems. The method includes separating the channel bandwidth of a message into a plurality of subcarriers having different subcarrier frequencies, where the subcarriers include data subcarriers and pilot subcarriers. The method demodulates the message in the receiver to extract symbols from the message and determines channel estimation frequency responses using a least-squares estimation process and the extracted symbols for the pilot subcarriers. The channel estimation frequency responses of either the pilot subcarriers, the pilot subcarriers and some data subcarriers, or the pilot subcarriers and all data subcarriers are used to generate updated channel estimation frequency responses, and a new channel estimation frequency response is generated for each extracted signal using a previous channel estimation frequency response and the updated channel estimation frequency response.