Abstract: Radiolabeled compounds of Formula I are described. Processes for radiolabeling the compounds are described. Methods for radioactive imaging using the compounds are also described.

Abstract: The present disclosure relates generally to the field of mammalian prosthetics, and more specifically to prostheses for use in total or partial joint replacement, and to a method of use of these prostheses in arthroplasty. Thus, disclosed is a prosthesis for use in hip arthroplasty that comprises an artificial femoral head that includes a head portion constructed totally or partially of a polymeric material, and a connector means designed to connect said head portion in a non-articulating manner to a femoral stem portion. The head portion may be made solely of solid polymeric material or of an outer shell of polymeric material connected in a non-articulating manner to an embedded core. The polymeric material is preferably selected from ultra-high molecular weight polyethylene (UHMWPE) or radiation treated UHMWPE having substantially no detectable free radicals. The embedded core comprises, for example, one or more of solid non-polymeric material (e.g.

Abstract: A classifier device for separating heavy materials from a stream of water and lighter materials includes an upper deck above lower deck, each deck having entrance and exit sides. The exit side of the lower deck terminates in a plurality of apertures. An exit plate is disposed adjacent the exit side of the upper deck and elevated relative thereto. A trap compartment is disposed below the exit plate and receives a removable trap that has an open top side and a plurality of pipes that each have at least one fluidizing aperture and that are aligned with one of the apertures of the lower deck. A classification plate is included between the exit side of the upper deck and the exit plate for directing the larger light materials up and over the exit plate back into the stream of water. Smaller materials drop through the classification plate into the trap.

Abstract: Methods of treating cancer or reducing the incidence of relapse of a cancer in a subject comprising co-administration of Toll-like receptor (TLR) 4 ligand, such as an HMGN1 protein, and a TLR 7 or 8 ligand, and optionally an immune checkpoint inhibitor, to the subject in need of such therapy. The TLR4-mediated immune-stimulating effect is synergistically enhanced by ligands of TLR7 or 8, and the immune checkpoint inhibitor. Also described here is a nanoparticle delivery platform for the co-administration of the TLR 4 ligand and the TLR 7 or 8 ligand.

Abstract: An electric motor may include a stator assembly comprising a stator housing, and one or more rotors coupled to the stator by a rotor shaft assembly. The stator housing may include a cooling structure that has a plurality of cooling body portions and a plurality of cooling conduits defined by the plurality of cooling body portions. A method of forming a stator housing for an electric machine may include additively manufacturing a stator housing that includes a cooling structure defining a fluid domain, coupling a working fluid source to the stator housing and introducing a working fluid into the fluid domain defined by the cooling structure, and sealing the cooling structure with the working fluid contained within the fluid domain of the cooling structure.

Abstract: An online incentive network is optimized. Online incentive network data is accessed including data regarding sharing between users of the network from at least one database. Inputted parameters and network data are applied to one or more models for incentivized deal sharing to determine profitability of an incentivized sharing deal to offer to plurality of users via an online network for one or more products or services provided by a merchant. The incentivized sharing deal comprises a deal in which a user purchases a particular deal, and then when the user shares the particular deal with a threshold number of other users who also purchase the deal, the user receives an incentive. The parameters include a price of the deal; a proportion of the deal kept by the merchant or the online incentive network, and the number of incentivized users. An interface offers the incentivized sharing deal to users.

Abstract: A liquid chromatography monitoring system comprises a computer or electronic controller comprising computer-readable instructions operable to: (a) draw a fluid into a syringe pump; (b) configure a valve so as to fluidically couple the pump to either a fluidic pathway through a fluidic system or to a plug that prevents fluid flow; (c) cause the syringe pump to progressively compress the fluid therein or expel the fluid to the fluidic pathway, while measuring a pressure of the fluid; (d) determine a profile of the variation of the measured pressure; (e) compare the determined profile to an expected profile that depends upon the fluid; and (f) provide a notification of a sub-optimal operating condition or malfunction if the determined profile varies from the expected profile by greater than a predetermined tolerance.

Abstract: A wind turbine is presented. The wind turbine includes a rotor having a plurality of blades. The wind turbine further includes a shaft coupled to the rotor. Moreover, the wind turbine includes a superconducting generator coupled to the rotor via the shaft. The superconducting generator includes an armature configured to be rotated via the shaft. The superconducting generator further includes a stationary field disposed concentric to and radially outward from the armature.

Abstract: The present invention is directed to a method of making an asymmetric polysulfide, comprising the step of simultaneously reacting an olefinically unsaturated compound, elemental sulfur, and a thiol in the presence of a catalytic amount of a base to produce the asymmetric polysulfide.

Abstract: A fuel system is provided that includes a fuel system frame and in some cases access steps. The frame can be mounted to a vehicle frame rail. Bracket assemblies can be coupled to the fuel system frame at a plurality of positions. The fuel tank can be mounted at neck portions thereof and can be supported on the frame rail between the neck portion, e.g., spaced a distance from the neck portions in a longitudinal direction of the fuel system. The access steps can be non-rectangular to provide a wide stepping portion even if the fuel system includes large tanks. The steps can be directly supported by an outside surface of the tank.

Abstract: Techniques for using signed nonces to secure cloud shells are provided. The techniques include receiving, by a session manager service, a request to connect a user device to a secure connection to a secure shell instance. The session manager service may authorize the user device to access the secure shell instance and may configure the secure shell instance, being described by a shell identifier of the secure shell instance. The techniques also include generating, by the session manager service, a nonce token and providing the shell identifier, and a router address of the secure shell router to the user device. The techniques also include generating, by the session manager service, a signed nonce token using the nonce token; and providing the signed nonce token and the shell identifier to a user device.

Abstract: A web harness system includes a web harness belt. The web harness belt including: multiple layers, and a first elastomer layer portion and a second elastomer portion that each connected to a ballistic material layer of the multiple layers. A webbing is connected through the web harness belt. The webbing forms a leg harness portion that includes: a first leg extension connected to a rear lower web support element, a second leg extension is connected to the rear lower web support element; a right leg adjustment belt is connected to the rear lower web support element and a first right leg extension element; and a left leg adjustment belt is connected to the rear lower web support element and a first left leg extension element.

Abstract: A rotary vegetation cutting unit having: a frame having a drive shaft; at least one cutting element that moves with the frame; and a debris blocking assembly on the frame with a unitary part that moves relative to the frame in opposite directions around an operating axis. The unitary part is configured to deflect away from the at least one cutting element objects approaching the at least one cutting element in a radial direction. The rotary vegetation cutting unit further has a bearing assembly including: a) a bearing that guides movement between the unitary part and the shaft; and b) a holder for the bearing. The rotary vegetation cutting unit is configured so that any debris spaced radially from the rotary vegetation cutting unit is required to traverse a non-straight path to contact the bearing.

Abstract: The present disclosure provides human IL-2 variants, recombinant oncolytic viruses comprising the IL-2 variant, compositions comprising the IL-2 variant or recombinant oncolytic virus, and use of the IL-2 variants, recombinant oncolytic virus, or compositions for treating cancer in an individual.

Abstract: Systems, methods, and software are disclosed herein for enhancing functions and formulas in spreadsheets. A computing apparatus detects a beginning of a formula in a cell of a spreadsheet. In response to detecting the beginning of the formula, the computing apparatus identifies one or more vector representations of a context of the cell and supplies the one or more vector representations as input to one or more machine learning models. The one or more machine learning models produce output comprising one or more suggested functions for the formula and one or more suggested operands, which the computing apparatus presents in a user interface to the spreadsheet.

Abstract: It has been unexpected found that silylated triglyceride oils can be incorporated into tire tread rubber formulations that include reinforcing fillers to provide improved wet traction characteristic, rolling resistance, and tread-wear without compromising cured stiffness (dry traction) and ultimate properties (chip/chunk resistance). The level of silica coupling agent needed in such formulation can also typically reduced. The present invention more specifically discloses a rubber formulation which is comprised of (1) a rubbery polymer; (2) a reinforcing filler, such as silica or carbon black; and (3) a silylated triglyceride oil. The silylated triglyceride oil will include silyl groups of the structural formula: —(CH2)n—Si(OR)3, wherein n represents an integer within the range of 1 to 8, and wherein R represents an alkyl group containing from 1 to 8 carbon atoms.

Abstract: An engine includes: a first rotating component; a second rotating component separate from the first rotating component; and an electric machine, the electric machine including a first rotor rotatable with the first rotating component; a second rotor rotatable with the second rotating component; and a stator assembly arranged between the first rotor and the second rotor, the stator assembly including a first set of windings arranged adjacent to the first rotor, a second set of windings arranged adjacent to the second rotor, and a non-ferromagnetic inner housing arranged between the first set of windings and the second set of windings.

Abstract: Embodiments of a photovoltaic device are provided herein. The photovoltaic device can include a layer stack and an absorber layer disposed on the layer stack. The absorber layer can include a first region and a second region. Each of the first region of the absorber layer and the second region of the absorber layer can include a compound comprising cadmium, selenium, and tellurium. An atomic concentration of selenium can vary across the absorber layer. The first region of the absorber layer can have a thickness between 100 nanometers to 3000 nanometers. The second region of the absorber layer can have a thickness between 100 nanometers to 3000 nanometers. A ratio of an average atomic concentration of selenium in the first region of the absorber layer to an average atomic concentration of selenium in the second region of the absorber layer can be greater than 10.

Abstract: Disclosed herein are replaceable filter frame gaskets and air filters having the same. The gasket is secured elastically to a filter frame of the air filter, making the gasket easily reusable and removable from the air filter.

Abstract: A device and method for identifying a center of a striking face of a golf club head are disclosed. The center determining device includes a device body having a central opening defined through a first surface of said device body and a second surface opposite said first surface. A first dimension indicator including a pair of first indicator jaws and a second dimension indicator including a pair of second indicator jaws may be disposed on said device body. A first adjuster and a second adjuster are operable to adjust said first separation distance said pair of first indicator jaws and a second separation distance between said second indicator jaws. When the pair of first indicator jaws and the pair of second indicator jaws are equally spaced around the heel, toe, topline, and sole edges of the striking face, the central opening is aligned with the center of the striking face.