Abstract: Provided herein are molecules having an antigen binding fragment that immunospecifically binds to BTN1A1, such as anti-BTN1A1 antibodies. These molecules include those having an antigen binding fragment that immunospecifically binds to glycosylated BTN1A1, such as anti-glycosylated BTN1A1 antibodies. Methods of making and using these molecules are also provided, including methods of using them in cancer therapies, or as cancer diagnostics.

Abstract: A pixel for an ambient light and/or color sensor includes a plurality of pinned photodiodes. The pixel also includes a floating diffusion region. A ratio of an active area of the plurality of pinned photodiodes to an area of the floating diffusion region is greater than 150.

Abstract: The invention relates to imidazopyridines of Formula (I) and pharmaceutically acceptable salts thereof, wherein R0 to R5 are as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The benzimidazoles of Formula (I) are ITK inhibitors and are therefore potentially useful in the treatment of a wide range of disorders including, atopic dermatitis.

Abstract: An example device is to monitor communications throughput rates and select modulation and coding protocols in order to minimize specific absorption rates experienced by users of the devices by minimizing or reducing transmission power settings.

Abstract: A computing system accesses one or more code lists, each including a plurality of items, each item comprising an alphanumerical machine code mapped to a human recognizable concept. The system may receive a query from a user, determine any matching and/or related items in the code lists, and generate an interactive visualization of the matching items. The visualization allows the user to view and detect relationships between items from multiple code lists in a manner that is not possible through review of the lists separately. The user can select nodes in a tree structured visualization to initiate addition of the corresponding alphanumerical machine codes to a custom code list.

Abstract: A method for identifying a set of optimized financing programs to provide to a merchant may include receiving historical loan application data defining historical parameters associated with corresponding historical loan applications, replacing at least a portion of the historical parameters of the historical loan application data with new parameters associated with different loan terms to define a simulated loan data set defining simulated financing programs, determining a selection probability score for each of the simulated financing programs, the selection probability score indicating a likelihood of customer selection of each respective one of the simulated financing programs, determining a cash flow rating for each of the simulated financing programs, the cash flow rating estimating cash flow over time for the each respective one of the simulated financing programs, determining a valuation score based on the selection probability score and the cash flow rating of the each respective one of the simulated

Abstract: A skin care emulsion composition that includes a continuous phase and a dispersed phase containing one or more retinoids. The continuous phase has a preservative system that includes one or more cell wall disrupters. The preservative system can be free of DMDM hydantoin, imadazolidinyl urea, diazlidinyl urea, sodium hydroxyl, methyl glycinate. The continuous phase can also include one or more antioxidants and one or more reducing agents. The composition can be chemically and physically stable.

Abstract: An example computing device includes a first housing portion, a second housing portion moveably connected to the first housing portion, a link to selectively secure the second housing portion to the first housing portion to inhibit movement of the second housing portion relative to the first housing portion, and a shape-memory alloy element to release the link to allow the second housing portion to move relative to the first housing portion.

Abstract: In some implementations, an optical device for mounting in a flip-chip configuration includes a plurality of flip-chip bumps that are arranged in a pattern on the optical device, wherein the pattern is not aligned with a crystal cleavage plane associated with a substrate of the optical device. In some implementations, the optical device further includes a gap that separates a primary region of the optical device and a secondary region of the optical device, wherein at least one portion of a side of the gap is oriented at a non-zero angle to the crystal cleavage plane.

Abstract: The invention provides isoform-selective anti-TGF? antibodies and methods of using the same. In particular, isoform-selective anti-TGF?2, anti-TGF?3, and anti-TGF?2/3 monoclonal antibodies are provided, e.g., for the treatment of fibrosis and other TGF?-related disorders.

Abstract: The present disclosure provides for methods of activating an immune cell in a subject by administering to the subject a CYR61 activating agent, as well as methods of treating ocular neovascularization in a subject by administering a CYR61 activating agent to an immune cell to form a treated immune cell and administering the treated immune cell to the subject.

Abstract: A foam maker has a bucket and a lid. The bucket has an outlet port provided in one of its walls, and a delivery tube connected to the outlet port. The lid includes a lid base and a lid top. The lid base has a frame and a compartment that receives a fan, a motor coupled to the fan, and a fluid inlet port through which foam solution and water can be introduced. The lid top has a water/foam inlet opening that is aligned with the fluid inlet port, and an air inlet port that is positioned adjacent the fan. An air tube is disposed inside the bucket, and has a first end connected to the lid base and communicating with the fan, and an opposite second end having an open distal end that is immersed inside foam solution. The air tube further includes an air chamber positioned adjacent the open distal end.

Abstract: A ride-on toy has a base having a front piece and a rear piece, each of the front piece and the rear piece having a plurality of leg housings. The base further includes at least one connecting strap that removably connects the front piece and the rear piece. The ride-on toy also includes an inflatable body having a body portion and a plurality of legs, with each of the plurality of legs inserted into a corresponding one of the plurality of leg housings. The ride-on toy also includes a plurality of wheel holders, each wheel holder having a foot housing and an ankle section extending upwardly from the foot housing, with a rotatable wheel secured inside the foot housing, and with the ankle section inserted into a corresponding one of the plurality of leg housings.

Abstract: A sea scooter has a main housing, a left arm pivotably attached to the left side of the main housing, a right arm pivotably attached to the right side of the main housing, a left barrel secured to the left arm, and a right barrel secured to the right arm. Each barrel has a fan and a motor for propelling the sea scooter through water. The left and right arms are locked by the first and second locking assemblies into a folded configuration against the left and right sides of the main housing when the sea scooter is not in use, and the left and right arms are pivoted away from the left and right sides of the main housing in a use configuration when the sea scooter is in use in the water. The motor is sand-proof and water-proof.

Abstract: A foam maker has a bucket and a lid. The bucket has an outlet port provided in one of its walls, and a delivery tube connected to the outlet port. The lid includes a lid base and a lid top. The lid base has a frame and a compartment that receives a fan, a motor coupled to the fan, and a fluid inlet port through which foam solution and water can be introduced. The lid top has a water/foam inlet opening that is aligned with the fluid inlet port, and an air inlet port that is positioned adjacent the fan. An air tube is disposed inside the bucket, and has a first end connected to the lid base and communicating with the fan, and an opposite second end having an open distal end that is immersed inside foam solution. The air tube further includes an air chamber positioned adjacent the open distal end.

Abstract: A ride-on toy has a base having a front piece and a rear piece, each of the front piece and the rear piece having a plurality of leg housings. The base further includes at least one connecting strap that removably connects the front piece and the rear piece. The ride-on toy also includes an inflatable body having a body portion and a plurality of legs, with each of the plurality of legs inserted into a corresponding one of the plurality of leg housings. The ride-on toy also includes a plurality of wheel holders, each wheel holder having a foot housing and an ankle section extending upwardly from the foot housing, with a rotatable wheel secured inside the foot housing, and with the ankle section inserted into a corresponding one of the plurality of leg housings.

Abstract: A sea scooter has a main housing, a left arm pivotably attached to the left side of the main housing, a right arm pivotably attached to the right side of the main housing, a left barrel secured to the left arm, and a right barrel secured to the right arm. Each barrel has a fan and a motor for propelling the sea scooter through water. The left and right arms are locked by the first and second locking assemblies into a folded configuration against the left and right sides of the main housing when the sea scooter is not in use, and the left and right arms are pivoted away from the left and right sides of the main housing in a use configuration when the sea scooter is in use in the water. The motor is sand-proof and water-proof.

Abstract: Disclosed are a projection module, a structured light three-dimensional imaging device, and an electronic apparatus. The projection module includes a laser emitter and a reflective grating. The laser emitter includes a light emitting surface from which laser light is emitted. The reflective grating includes a reflecting surface arranged obliquely relative to the light emitting surface and opposite to the light emitting surface. The reflective face is provided with a grating microstructure thereon. The projection module can adjust a reflection angle of the laser light when expanding beams to generate a laser pattern.