Patents by Inventor Joseph Ready

Joseph Ready has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR PROMOTING NEUROGENESIS AND INHIBITING NERVE CELL DEATH
    Publication number: 20210100778
    Abstract: A method of promoting neuroprotection in a subject from axonal degeneration, neuronal cell death, and/or glia cell damage after injury, augmenting neuronal signaling underlying learning and memory, stimulating neuronal regeneration after injury, and/or treating a disease, disorder, and/or condition of the nervous system in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
    Type: Application
    Filed: August 18, 2020
    Publication date: April 8, 2021
    Inventors: Sanford MARKOWITZ, Joseph READY, Andrew PIEPER
  • COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY
    Publication number: 20210094968
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Application
    Filed: May 8, 2020
    Publication date: April 1, 2021
    Inventors: Sanford Markowitz, Joseph Ready, Yongyou Zhang, Monika Antczak, James K.V. Willson, Bruce Posner, William Greenlee
  • COMPOSITIONS AND METHODS OF MODULATING 15-PGDH ACTIVITY
    Publication number: 20210032265
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors and 15-PGDH activators described herein.
    Type: Application
    Filed: July 30, 2020
    Publication date: February 4, 2021
    Inventors: Sanford Markowitz, James K.V. Willson, Bruce Posner, Joseph Ready, Yongyou Zhang, Hsin-Hsiung Tai, Monika Antczak, Stanton Gerson, KiBeom Bae, Sung Yeun Yang, Amar Desai
  • Compositions and methods of modulating short-chain dehydrogenase activity
    Patent number: 10869871
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: December 22, 2020
    Assignees: CASE WESTERN RESERVE UNIVERSITY, THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Sanford Markowitz, James K.V. Wilson, Bruce Posner, Joseph Ready, Monika Antczak, Yongyou Zhang, Amar Desai, Stanton Gerson, William Greenlee, Sung Yeun Yang, KiBeom Bae
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR MODULATING HEMATOPOIETIC STEM CELLS AND HEMATOPOIESIS
    Publication number: 20200147063
    Abstract: A method of modulating hematopoietic stem cells and hematopoiesis includes administering to a subject in need thereof a 15-PGDH inhibitor.
    Type: Application
    Filed: September 24, 2019
    Publication date: May 14, 2020
    Inventors: Sanford Markowitz, Amar Desai, Joseph Ready
  • COMPOSITIONS AND METHODS OF MODULATING 15-PGDH ACTIVITY
    Publication number: 20200140453
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors and 15-PGDH activators described herein.
    Type: Application
    Filed: May 24, 2019
    Publication date: May 7, 2020
    Inventors: Sanford Markowitz, James K.V. Willson, Bruce Posner, Joseph Ready, Youngyou Zhang, Hsin-Hsiung Tai, Monika Antczak, Stanton Gerson, KiBeom Bae, Sung Yeun Yang, Amar Desai
  • COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE
    Publication number: 20200095206
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Application
    Filed: February 6, 2018
    Publication date: March 26, 2020
    Inventors: Sanford Markowitz, Yiyuan Yuan, Yongyou Zhang, Joseph Ready, Bin Hu
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING CORONARY DISORDERS
    Publication number: 20200030348
    Abstract: A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
    Type: Application
    Filed: April 9, 2018
    Publication date: January 30, 2020
    Inventors: Sanford Markowitz, Won Jin Ho, Yiyuan Yuan, Mukesh Jain, Mohamed Sabeh, Joseph Ready, Noelle Williams
  • COMPOSITIONS AND METHODS OF MODULATING SHIRT-CHAIN DEHYDROGENASE ACTIVITY
    Publication number: 20190365769
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Application
    Filed: October 16, 2017
    Publication date: December 5, 2019
    Inventors: Sanford Markowitz, James K.V. Willson, Bruce Posner, Joseph Ready, Monika Antczak, Yongyou Zhang, Amar Desai, Stanton Gerson, William Greenlee, Sung Yeun Yang, KiBeom Bae
  • Inhibitors of short-chain dehydrogenase activity for modulating hematopoietic stem cells and hematopoiesis
    Patent number: 10420752
    Abstract: A method of modulating hematopoietic stem cells and hematopoiesis includes administering to a subject in need thereof a 15-PGDH inhibitor.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: September 24, 2019
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Sanford Markowitz, Amar Desai, Joseph Ready
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR PROMOTING NEUROGENESIS AND INHIBITING CELL DEATH
    Publication number: 20190275014
    Abstract: A method of promoting neuroprotection in a subject from axonal degeneration, neuronal cell death, and/or glia cell damage after injury, augmenting neuronal signaling underlying learning and memory, stimulating neuronal regeneration after injury, and/or treating a disease, disorder, and/or condition of the nervous system in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
    Type: Application
    Filed: July 18, 2017
    Publication date: September 12, 2019
    Applicants: Case Western Reserve University, University of Texas Southwestern Medical Center, University of Iowa Research Foundation
    Inventors: Sanford MARKOWITZ, Joseph READY, Andrew PIEPER
  • Compositions and methods of modulating 15-PGDH activity
    Patent number: 10301320
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors and 15-PGDH activators described herein.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: May 28, 2019
    Assignees: University of Kentucky Research Foundation, Case Western Reserve University, Board of Regents of the University of Texas System
    Inventors: Sanford Markowitz, James K. V. Willson, Bruce Posner, Joseph Ready, Youngyou Zhang, Hsin-Hsiung Tai, Monika Antczak, Stanton Gerson, KiBeom Bae, Sung Yeun Yang, Amar Desai
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR MODULATING HEMATOPOIETIC STEM CELLS AND HEMATOPOIESIS
    Publication number: 20180125829
    Abstract: A method of modulating hematopoietic stem cells and hematopoiesis includes administering to a subject in need thereof a 15-PGDH inhibitor.
    Type: Application
    Filed: October 31, 2017
    Publication date: May 10, 2018
    Inventors: Sanford Markowitz, Amar Desai, Joseph Ready
  • COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY
    Publication number: 20180118756
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Application
    Filed: April 14, 2016
    Publication date: May 3, 2018
    Inventors: Sanford Markowitz, Joseph Ready, Yongyou Zhang, Monika Antczak, James K.V. Willson, Bruce Posner, William Greenlee
  • Inhibitors of short-chain dehydrogenase activity for modulating hematopoietic stem cells and hematopoiesis
    Patent number: 9801863
    Abstract: A method of modulating hematopoietic stem cells and hematopoiesis includes administering to a subject in need thereof a 15-PGDH inhibitor.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: October 31, 2017
    Assignees: Case Western Reserve University, Board of Regents of the Univeristy of Texas System
    Inventors: Sanford Markowitz, Amar Desai, Stanton Gerson, Joseph Ready
  • Compositions and methods of modulating 15-PGDH activity
    Patent number: 9790233
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors and 15-PGDH activators described herein.
    Type: Grant
    Filed: April 16, 2013
    Date of Patent: October 17, 2017
    Assignees: Case Western Reserve University, Board of Regents of the University of Texas System, University of Kentucky Research Foundation
    Inventors: Sanford Markowitz, James K. V. Willson, Bruce A. Posner, Joseph Ready, Yongyou Zhang, Hsin-Hsiung Tai, Monika Antczak, Stanton Gerson, KiBeom Bae, Sung Yeun Yang, Amar Desai
  • Compositions and methods of modulating short-chain dehydrogenase activity
    Patent number: 9789116
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: October 17, 2017
    Assignees: Case Western Reserve University, Board of Regents of the University of Texas System
    Inventors: Sanford Markowitz, James K. V. Willson, Bruce Posner, Joseph Ready, Monika Antczak, Yongyou Zhang, Amar Desai, Stanton Gerson, William Greenlee
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR MODULATING HEMATOPOIETIC STEM CELLS AND HEMATOPOIESIS
    Publication number: 20170216265
    Abstract: A method of modulating hematopoietic stem cells and hematopoiesis includes administering to a subject in need thereof a 15-PGDH inhibitor.
    Type: Application
    Filed: November 9, 2016
    Publication date: August 3, 2017
    Inventors: Sanford Markowitz, Amar Desai, Stanton Gerson, Joseph Ready
  • COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY
    Publication number: 20170173028
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Application
    Filed: October 15, 2014
    Publication date: June 22, 2017
    Inventors: Sanford Markowitz, James K.V. Willson, Bruce Posner, Joseph Ready, Monika Antczak, Youngyou Zhang, Amar Desai, Stanton Gerson, William Greenlee
  • COMPOSITIONS AND METHODS OF MODULATING 15-PGDH ACTIVITY
    Publication number: 20170165241
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors and 15-PGDH activators described herein.
    Type: Application
    Filed: November 22, 2016
    Publication date: June 15, 2017
    Inventors: Sanford Markowitz, James K.V. Willson, Bruce Posner, Joseph Ready, Youngyou Zhang, Hsin-Hsiung Tai, Melissa Moss, Monika Antczak, Stanton Gerson, KiBeom Bae, Sung Yeun Yang, Amar Desai