Patents by Inventor Joseph Schmidt
Joseph Schmidt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9993441Abstract: A biocompatible polymeric controlled release matrix barrier structure for delivery of one or more bioactive agents from an implantable medical device is described. In an embodiment, a biocompatible polymeric controlled release matrix barrier structure is included. The biocompatible polymeric controlled release matrix can include a body structure formed of a compliant material comprising one or more compliant biocompatible polymers and one or more bioactive agents. The body structure can define a central aperture through which a subcutaneous element of an implantable medical device passes. Other embodiments are included herein.Type: GrantFiled: March 26, 2015Date of Patent: June 12, 2018Assignee: Surmodics, Inc.Inventors: Joseph Schmidt McGonigle, Aleksey V. Kurdyumov, Jeffrey J. Missling, Nathan A. Lockwood, Kevin W. Burton, Beth A. Petersen
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Publication number: 20180028742Abstract: A patient care system is disclosed that includes a medical device such as an infusion pump. The medical device generates a data message containing information such as the status of the therapy being delivered, operating data or both. An alarm generating system assesses the data message from the pump and generates an alarm message if certain conditions established by a first set of rules are met. The alarm message is assessed according to a second set of rules as to whether to suppress the alarm message. The data message contains a required input for both the first and second algorithms. A dispatching system is adapted to forward the alarm message to an alarm destination according to a third set of rules. The alarm destination expresses an alarm upon receipt of the alarm message.Type: ApplicationFiled: August 11, 2017Publication date: February 1, 2018Inventors: William Kenneth Day, Steve Joseph Lindo, Paul John Foryt, Justin Joseph Schmidt, Robert Cousineau, Michael Kremliovsky, Sumant Ramachandra, Anatoly S. Belkin, Gary Mills
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Publication number: 20170281907Abstract: Embodiments herein include an insertion tool for inserting a medical device into another medical device, such as a hemostasis sealing valve, and related methods. In an embodiment, an insertion tool includes a guide sheath and a protection tube. The guide sheath can include a flared proximal end. The guide sheath can further include a central lumen. The guide sheath can further include a locking notch disposed on the inner surface between the proximal end and the distal end. The protection tube can include a flared proximal end. A portion of the protection tube can be situated within the central lumen of the guide sheath. The flared proximal end of the protection tube can be sized to fit within the locking notch and can have an outer diameter larger than portions of the inner surface immediately adjacent to the locking notch. Other embodiments are also included herein.Type: ApplicationFiled: March 23, 2017Publication date: October 5, 2017Inventors: Bruce M. Jelle, Joram Slager, Joseph Schmidt McGonigle, Nathan A. Lockwood
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Patent number: 9764082Abstract: A patient care system is disclosed that includes a medical device such as an infusion pump. The medical device generates a data message containing information such as the status of the therapy being delivered, operating data or both. An alarm generating system assesses the data message from the pump and generates an alarm message if certain conditions established by a first set of rules are met. The alarm message is assessed according to a second set of rules as to whether to suppress the alarm message. The data message contains a required input for both the first and second algorithms. A dispatching system is adapted to forward the alarm message to an alarm destination according to a third set of rules. The alarm destination expresses an alarm upon receipt of the alarm message.Type: GrantFiled: April 30, 2015Date of Patent: September 19, 2017Assignee: ICU Medical, Inc.Inventors: William Kenneth Day, Steve Joseph Lindo, Paul John Foryt, Justin Joseph Schmidt, Robert Cousineau, Michael Kremliovsky, Sumant Ramachandra, Anatoly S. Belkin, Gary Mills
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Publication number: 20170072057Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In a more specific embodiment, the cationic delivery agent includes branched PEI. Methods of making the delivery composition, as well as kits and methods of use are also disclosed.Type: ApplicationFiled: November 21, 2016Publication date: March 16, 2017Inventors: Joseph Ventura, Shannon Wadman, Joram Slager, Joseph Schmidt McGonigle, Robert W. Hergenrother
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Patent number: 9555119Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In a more specific embodiment, the cationic delivery agent includes branched PEI. Methods of making the delivery composition, as well as kits and methods of use are also disclosed.Type: GrantFiled: November 5, 2013Date of Patent: January 31, 2017Assignee: Surmodics, Inc.Inventors: Joseph Ventura, Shannon Wadman, Joram Slager, Joseph Schmidt McGonigle, Robert W. Hergenrother
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Publication number: 20160375456Abstract: A tool for aiming a nozzle assembly having a fluid outlet and a cap is provided. The tool includes a housing defining a bore. The bore has a side wall radially disposed about an axis. The tool also includes a laser assembly including a laser emission source configured to produce a light beam collinear with the axis of the housing. The laser assembly also includes a power supply. The tool further includes at least one of a switch and an electrical contact provided within the housing and adapted to be in electrical communication with the power supply and the laser emission source based on a contact with the nozzle assembly. The tool is installed on the nozzle assembly such that the bore is adapted for placement about an outer surface of the nozzle assembly so that the fluid outlet is substantially concentric about the axis.Type: ApplicationFiled: September 12, 2016Publication date: December 29, 2016Applicant: Caterpillar Inc.Inventors: Christian Rath, Austin Joseph Schmidt
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Publication number: 20160361878Abstract: A method for evaluating part for additive manufacturing is provided. The method includes receiving data related to a set of printability factors associated with the part. The set of printability factors comprise at least: an availability of a three dimensional printer, a build density, a fraction of part to be printed, a print accuracy, a part complexity, and a number of parts needed. The method includes evaluating a printability index associated with the part based on at least three printability factors from the set of printability factors. Further, the method includes displaying the printability index associated with the part for the evaluation of the part for additive manufacturing.Type: ApplicationFiled: August 25, 2016Publication date: December 15, 2016Applicant: Caterpillar Inc.Inventors: Arun Lal Gain, Marchione Thierry Andre, Austin Joseph Schmidt, Yihong Yang, Nathan John Parsons
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Publication number: 20160256622Abstract: Aspects of the present disclosure provide systems, devices, and methods for delivering substances such as fluids, solutions, medications, and drugs to patients using infusion devices having a set of advanced features. These advanced features include aspects related to the programming of infusion devices, the configuration of infusion sequences performed by the infusion devices, and the interconnection of multiple infusion devices for interoperation during an infusion having a sequence of infusion steps.Type: ApplicationFiled: March 1, 2016Publication date: September 8, 2016Inventors: William Kenneth Day, Justin Joseph Schmidt, Steve Joseph Lindo, Paul John Foryt
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Publication number: 20160089480Abstract: Embodiments of the invention include medical device elements formed from polymers with lubricious properties. In an embodiment, a method of forming a medical device element is included. The method can include mixing a first polymeric component and a second polymeric component to form a polymer mixture. The method can further include forming the polymer mixture into the medical device element. The method can also include treating the polymer mixture with at least one of an acid or a base. In an embodiment, a medical device is included. The medical device can include a lubricious element, the lubricious element comprising a mixture of a first polymeric component and a second polymeric component. The second polymeric component can include a polymer that is treated with at least one of an acid or a base after formation of the element. Other embodiments are also included herein.Type: ApplicationFiled: September 21, 2015Publication date: March 31, 2016Inventors: Ralph A. Chappa, Nathan A. Lockwood, Joseph Schmidt McGonigle
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Publication number: 20150317891Abstract: A patient care system is disclosed that includes a medical device such as an infusion pump. The medical device generates a data message containing information such as the status of the therapy being delivered, operating data or both. An alarm generating system assesses the data message from the pump and generates an alarm message if certain conditions established by a first set of rules are met. The alarm message is assessed according to a second set of rules as to whether to suppress the alarm message. The data message contains a required input for both the first and second algorithms. A dispatching system is adapted to forward the alarm message to an alarm destination according to a third set of rules. The alarm destination expresses an alarm upon receipt of the alarm message.Type: ApplicationFiled: April 30, 2015Publication date: November 5, 2015Inventors: William Kenneth Day, Steve Joseph Lindo, Paul John Foryt, Justin Joseph Schmidt, Robert Cousineau, Michael Kremliovsky, Sumant Ramachandra, Anatoly S. Belkin, Gary Mills
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Publication number: 20150196497Abstract: A biocompatible polymeric controlled release matrix barrier structure for delivery of one or more bioactive agents from an implantable medical device is described. In an embodiment, a biocompatible polymeric controlled release matrix barrier structure is included. The biocompatible polymeric controlled release matrix can include a body structure formed of a compliant material comprising one or more compliant biocompatible polymers and one or more bioactive agents. The body structure can define a central aperture through which a subcutaneous element of an implantable medical device passes. Other embodiments are included herein.Type: ApplicationFiled: March 26, 2015Publication date: July 16, 2015Inventors: Joseph Schmidt McGonigle, Aleksey V. Kurdyumov, Jeffrey J. Missling, Nathan A. Lockwood, Kevin W. Burton, Beth A. Petersen
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Patent number: 8936811Abstract: Embodiments of the invention include particles with nucleic acid complexes, medical devices including the same and related methods. In an embodiment, the invention can include a method of making a medical device. The method can include contacting nucleic acids with cationic carrier agents to form nucleic acid complexes, adsorbing the nucleic acid complexes to porous particles to form nucleic acid complex containing particles, mixing the nucleic acid complex containing particles with a polymer solution to form a coating mixture, and applying the coating mixture to a substrate. In an embodiment, the method can include contacting nucleic acids with cationic carrier agents to form nucleic acid complexes, combining the nucleic acid complexes with a material to form nucleic acid complex containing particles in situ, mixing the nucleic acid complex particles with a polymer solution to form a coating mixture, and applying the coating mixture to a substrate.Type: GrantFiled: May 7, 2009Date of Patent: January 20, 2015Assignee: SurModics, Inc.Inventors: Joram Slager, Joseph Schmidt McGonigle
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Publication number: 20140336571Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In an embodiment, the invention includes a drug delivery device including a substrate; and coated therapeutic agent particles disposed on the substrate, the coated therapeutic agent particles comprising a particulate hydrophobic therapeutic agent; and a vinyl amine polymer. Methods of making the delivery composition, as well as kits and methods of use are also included herein.Type: ApplicationFiled: May 16, 2014Publication date: November 13, 2014Applicant: SurModics, Inc.Inventors: Joram Slager, Dale G. Swan, Darin DuMez, Joseph Ventura, Shannon Wadman, Joseph Schmidt McGonigle, Robert W. Hergenrother
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Patent number: 8883208Abstract: Embodiments of the invention include devices and methods for the release of nucleic acid complexes. In an embodiment the invention includes a nucleic acid delivery particle. The delivery particle can include a polymeric matrix including a polyethyleneglycol containing copolymer and a nucleic acid complex disposed within the polymeric matrix. The nucleic acid complex can include a nucleic acid and a carrier agent. In an embodiment the invention includes a medical device including a first polymeric matrix comprising a first polymer and a plurality of nucleic acid delivery particles disposed within the first polymeric matrix. The medical device can be configured to release the nucleic acid complex when the medical device is implanted within a subject. Other embodiments are included herein.Type: GrantFiled: April 8, 2010Date of Patent: November 11, 2014Assignee: SurModics, Inc.Inventors: Joseph Schmidt McGonigle, Joram Slager
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Publication number: 20140200411Abstract: Disclosed herein are activatable conductive compositions and methods of making and using activatable conductive compositions. In particular, activatable conductive monomers polymers are described and electrically conductive coatings that include activatable conductive polymers.Type: ApplicationFiled: January 10, 2014Publication date: July 17, 2014Applicant: SurModics, Inc.Inventors: Bruce M. Jelle, Aleksey V. Kurdyumov, Joseph Schmidt McGonigle, Robert W. Hergenrother, Nathan A. Lockwood, Joseph Ventura, Sean M. Stucke
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Publication number: 20140142166Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In a more specific embodiment, the cationic delivery agent includes branched PEI. Methods of making the delivery composition, as well as kits and methods of use are also disclosed.Type: ApplicationFiled: November 5, 2013Publication date: May 22, 2014Applicant: SurModics, Inc.Inventors: Joseph Ventura, Shannon Wadman, Joram Slager, Joseph Schmidt McGonigle, Robert W. Hergenrother
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Publication number: 20120084093Abstract: Methods of allocating raters to assessment visits of studies, and tangible computer readable media including software that is adapted to control a computer to implement methods of allocating raters to assessment visits of studies, are provided. Raters are allocated by retrieving blinding information that includes at least one blinding criterion for a visit of a study, retrieving rater information for at least one rater associated with the study, comparing the retrieved rater information and the retrieved blinding information to identify one or more raters meeting the at least one blinding criterion and enabling selection of the identified one or more raters for allocation to the visit of the study. A rater may then be allocated to the visit by receiving a selection for at least one of the identified raters and allocating the at least one rater to the visit responsive to the received selection.Type: ApplicationFiled: August 31, 2011Publication date: April 5, 2012Applicant: MEDAVANTE, INC.Inventors: Joseph SCHMIDT, Livingston JOHNSON, Matthew Clifford MASOTTI, Patricia SUKOVICH
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Publication number: 20110319473Abstract: Embodiments of the invention include devices and methods for delivery of nucleic acids as active agents. Embodiments of the invention include devices and methods for delivery of nucleic acids as active agents. In an embodiment, an article for delivering an active agent is included. The article can include a dehydrated complex including a nucleic acid, a transfection agent, and a saccharide protectant. The nucleic acid and transfection agent can form a liposome or a lipoplex. The dehydrated complex can be disposed within a polymeric matrix. The dehydrated complex can be disposed within a microparticle. Other embodiments are also included herein.Type: ApplicationFiled: June 28, 2011Publication date: December 29, 2011Applicant: SURMODICS, INC.Inventors: Joseph Schmidt McGonigle, Joram Slager
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Publication number: 20100260846Abstract: Embodiments of the invention include devices and methods for the release of nucleic acid complexes. In an embodiment the invention includes a nucleic acid delivery particle. The delivery particle can include a polymeric matrix including a polyethyleneglycol containing copolymer and a nucleic acid complex disposed within the polymeric matrix. The nucleic acid complex can include a nucleic acid and a carrier agent. In an embodiment the invention includes a medical device including a first polymeric matrix comprising a first polymer and a plurality of nucleic acid delivery particles disposed within the first polymeric matrix. The medical device can be configured to release the nucleic acid complex when the medical device is implanted within a subject. Other embodiments are included herein.Type: ApplicationFiled: April 8, 2010Publication date: October 14, 2010Applicant: SURMODICS, INC.Inventors: Joseph Schmidt McGonigle, Joram Slager