Abstract: The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these delivery agents form solvates with ethanol and hydrates with water. The delivery agents have the formula wherein R1, R2, R3, and R4 are indepedently hydrogen, halogen, C1-C4 alkyl, or C1-C4 alkoxy; and R5 is a substitued or unsubstituted C2-C16 alkylene, substituted or unsubstituted C2-C16 alkenylene, substituted or unsubstituted C1-C12 alkyl(arylene), or substituted or unsubstituted aryl(C1-C12 alkylene). The hydrates and solvates of present invention also have surprisingly greater efficacy for delivering active agents, such as heparin and calcitonin, than their corresponding monosodium salts and free acids. The present invention provides an alcohol solvate, such as ethanol solvate, of a disodium salt of a delivery agent of the formula above.

Abstract: Systems and methods for operating aircraft power systems are disclosed. A power system in accordance with one embodiment of the invention includes an aircraft auxiliary power unit and a controller coupled to the aircraft auxiliary power unit, with the controller being configured to automatically stop the auxiliary power unit while the auxiliary power unit is functioning normally. The controller can also be configured to automatically start the auxiliary power unit in-flight when power supplied or expected to be supplied to a subsystem of the aircraft has a non-zero value at or below a threshold value. The controller may also be configured to start the auxiliary power unit when a load or expected load on the subsystem meets or exceeds a threshold value.

Abstract: The invention relates to a composition for the treatment of a cyclooxygenase-2-mediated disorder or condition comprising 5-methyl-2-(2?-chloro-6?-fluoroanilino)phenylacetic acid or a pharmaceutically acceptable salt, preferably the potassium salt, thereof suitable for parenteral administration, and to a method for the treatment of a cyclooxygenase-2-mediated disorder or condition in a human or animal in need of such treatment by parenteral administration of 5-methyl-2-(2?-chloro-6?-fluroanilino)phenylacetic acid or a pharmaceutically acceptable salt, preferably the potassium salt, thereof.

Abstract: A method and system for displaying aircraft engine information. In one embodiment, the method includes directing the display of an icon that represents an overall operational state of an aircraft engine, with the overall operational state including one of a started state and an unstarted state. The method can further include directing a change in a displayed characteristic of the icon when the overall operational state of the aircraft engine changes from the one of the started state and the unstarted state to the other of the started state and the unstarted state. In a further embodiment, the method can further include repeatedly directing changes in the display of the icon as the aircraft changes from the unstarted state to the started state.

Abstract: A method and system for displaying aircraft engine information. In one embodiment, the method includes directing the display of an icon that represents a qualitative, overall operational state of an aircraft engine, with the overall operational state being determined from a plurality of engine operating parameters. The method can further include directing a change in the display of the icon when the overall operational state of the aircraft engine changes from a first overall operational state to a second operational state. In a further aspect of this embodiment, the change in the characteristic of the icon can include a change in the color or other visual characteristic of the icon, and the color or other visual characteristic of the icon can correspond directly to instructions to the pilot for actions suggested or required as a result of the current engine operational state.

Abstract: A method and system for displaying aircraft engine information. In one embodiment, the method includes directing the display of an icon that represents an overall operational state of an aircraft engine, with the overall operational state including one of a started state and an unstarted state. The method can further include directing a change in a displayed characteristic of the icon when the overall operational state of the aircraft engine changes from the one of the started state and the unstarted state to the other of the started state and the unstarted state. In a further embodiment, the method can further include repeatedly directing changes in the display of the icon as the aircraft changes from the unstarted state to the started state.

Abstract: A template device and method of using same, the template device includes: a substantially planar member defining a plurality of channels therein; wherein, the channels at least partially define a plurality of concentric shapes each corresponding to a known electrical box configuration, respectively. The device may include at least one leveling indicator such as a leveling bubble container. The device may include a stud finding device, or means for attaching to a stud finding device. The device may be integrated with, or include means for attaching to, a sheet rock square.

Abstract: Systems and methods for presenting information corresponding to circuit breakers and for controlling such circuit breakers are disclosed. In one embodiment, the system can include a menu-driven, pointer-accessible graphical user interface via which an operator can receive information corresponding to circuit breakers, and can automatically change the states of the circuit breakers. Menus of circuit breaker information can be organized by the state of the circuit breaker, the location of the circuit breaker, the bus to which the circuit breaker is coupled, the electrical system to which the circuit breaker belongs, and/or the system or subsystem of which the circuit breaker is a part. In further embodiments, the circuit breaker information can be organized according to custom-made arrangements.

Abstract: Solid pharmaceutical compositions suitable for the oral delivery of pharmacologically active agents, e.g. peptides, comprising a therapeutically-effective amount of a pharmacologically active agent; a crospovidone or povidone; and a delivery agent for said pharmacologically active agent are disclosed. The compositions provide excellent oral bioavailability of pharmacologically active agents, particularly calcitonin.

Abstract: Systems and methods for operating aircraft power systems are disclosed. A power system in accordance with one embodiment of the invention includes an aircraft auxiliary power unit and a controller coupled to the aircraft auxiliary power unit, with the controller being configured to automatically stop the auxiliary power unit while the auxiliary power unit is functioning normally. The controller can also be configured to automatically start the auxiliary power unit in-flight when power supplied or expected to be supplied to a subsystem of the aircraft has a non-zero value at or below a threshold value. The controller may also be configured to start the auxiliary power unit when a load or expected load on the subsystem meets or exceeds a threshold value.

Abstract: The invention provides methods and systems for providing priority processing to critical data as the data is transmitted across a network. A plurality of Internet protocol (IP) packets, each of which contains data and priority information, are received at a first router. The data contained in the IP packets is then encapsulated into frame relay frames containing the priority information. The frame relay frames are transmitted from the first router to a frame relay network in a manner determined by the priority information included in the frame relay frames. The frame relay frames are then transmitted across a frame relay network to a second router in a manner determined by the priority information included in the frame relay frames.

Abstract: A template device and method of using same, the template device including: a substantially planar member defining a plurality of channels therein; wherein, the channels at least partially define a plurality of concentric shapes each corresponding to a known electrical box configuration, respectively. The method includes positioning a template defining a plurality of channels at least partially defining a plurality of concentric shapes each corresponding to a known electrical box configuration, respectively, at least substantially adjacent to walling material; selecting a subset of the channels corresponding to one of the defined shapes and the electrical box to be received; and, creating an opening in the walling material dependently upon the selected subset of channels.

Abstract: A method and system for displaying aircraft engine information. In one embodiment, the method includes directing the display of an icon that represents a qualitative, overall operational state of an aircraft engine, with the overall operational state being determined from a plurality of engine operating parameters. The method can further include directing a change in the display of the icon when the overall operational state of the aircraft engine changes from a first overall operational state to a second operational state. In a further aspect of this embodiment, the change in the characteristic of the icon can include a change in the color or other visual characteristic of the icon, and the color or other visual characteristic of the icon can correspond directly to instructions to the pilot for actions suggested or required as a result of the current engine operational state.

Abstract: Solid pharmaceutical compositions suitable for the oral delivery of pharmacologically active agents, e.g. peptides, comprising a therapeutically-effective amount of a pharmacologically active agent; a crospovidone or povidone; and a delivery agent for said pharmacologically active agent are disclosed. The compositions provide excellent oral bioavailability of pharmacologically active agents, particularly calcitonin.

Abstract: An organic solvent soluble active agent containing water-insoluble hydrophilic hydrogel comprising a copolymer of (A) a water-soluble monoolefinic monomer or a mixture thereof optimally containing up to 50% thereof of one or more water-insoluble mono-olefinic monomers and (B) a terminally diolefinic hydrophobic macromer containing polypropylene oxide or polytetramethylene oxide units prepared in the presence of an effective macromer expanding amount of a macromer soluble compound of the formulaR'--R"--O.sub.n R"'where R', R", R"' and n are as defined in the claims, hydrogels useful in the loading of such active agents, their preparation, and use are disclosed.