Patents by Inventor Joshua Clayton

Joshua Clayton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11530736
    Abstract: A track system includes a track member with an elongate shaft mounted thereto. At least one support mechanism is mounted to the track member. The at least one support mechanism includes a housing. An engagement feature includes first and second engagement members spaced-apart from one another to define a receiving area therebetween. The first and second engagement members are operable between deployed and retracted positions relative to the housing. The elongate shaft is received in the receiving area when the first and second engagement members are in the deployed position.
    Type: Grant
    Filed: June 26, 2019
    Date of Patent: December 20, 2022
    Assignee: Ford Global Technologies, LLC
    Inventors: Joseph Michael Kish, Joshua Gauthier, Matthew Schwope, Robert Clayton Caldwell, Johnathan Andrew Line, Cung K. Chieu, Changwei Xie, Macit Aktas, Glenn Scott
  • Publication number: 20220287750
    Abstract: A surgical screw is provided for use in fixing or fusing bone. The screw may include each of an inner and an outer helical thread that extends along its length. The geometries of the helices and the relationship between the inner thread and the outer thread may improve the performance of the screw. For example, the two helices may operate to improve the manner in which the screw can be strained.
    Type: Application
    Filed: March 11, 2022
    Publication date: September 15, 2022
    Inventors: Liam Joseph Raymond McKay, Joshua Clayton Lyon, Rylan Reed, Randall F. Dryer, Ali Kiapour
  • Patent number: 11433785
    Abstract: A rail assembly can include a track assembly, an elongate shaft mounted to the track assembly, and a carriage assembly received within the track assembly. The carriage assembly can include a slider bracket. The slider bracket includes a first ramp portion and a second ramp portion. The first and second ramp portions are disposed on opposite sides of the slider bracket. The first and second ramp portions each define a receiving aperture. The elongate shaft is received through the receiving apertures of the first and second ramp portions.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: September 6, 2022
    Assignee: Ford Global Technologies, LLC
    Inventors: Macit Aktas, Joshua Gauthier, Joseph Michael Kish, Johnathan Andrew Line, Adarsh Gupta, Robert Clayton Caldwell, Changwei Xie
  • Publication number: 20220177426
    Abstract: Disclosed are processes for preparing ?-carboxamide pyrrolidine derivatives, in particular (2S,5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and intermediates for use in said processes along with processes for preparing said intermediates.
    Type: Application
    Filed: April 9, 2020
    Publication date: June 9, 2022
    Inventors: Donald G. Walker, Dino Alberico, Joshua Clayton, Chandrasekhar Navuluri
  • Publication number: 20200206046
    Abstract: A first aid trauma kit case that provides for a means of treating specific trauma injuries related to massive bleeding and tension pneumothorax. An embodiment of the first aid trauma kit case contains as part of its architecture an easily readable format for identifying an injury location and instructions, that are integrated as part of the case, on how to apply certain specific medical devices contained within the case. An embodiment of the case also provides for a color-coded identification system for easy identification of the preferred treatment method for the suffered trauma injury. The design of the integrated instructions and the color-coded system work in tandem to provide for a quick method of identifying and treating specific types of trauma related injuries.
    Type: Application
    Filed: January 2, 2019
    Publication date: July 2, 2020
    Inventors: Joshua Clayton, David Thomposon, Phillip Harris
  • Patent number: 9403864
    Abstract: Disclosed is a process for preparing a carbonucleoside of formula (1) and intermediates for use therein. The process involves the step of reacting a compound of formula (2) with a compound of formula (3) under Mitsunobu-type reaction conditions to obtain a compound of formula (4), wherein PG1, PG2, PG3 and PG4 are protecting groups. The compound of formula (4) is deprotected to form the compound of formula (1), as shown below.
    Type: Grant
    Filed: May 30, 2011
    Date of Patent: August 2, 2016
    Assignee: Alphora Research Inc.
    Inventors: Dino Alberico, Joshua Clayton, Craig Dixon, Boris Gorin
  • Patent number: 8658792
    Abstract: Anti-virally active carbanucleosides such as entecavir are prepared by a process which utilizes, throughout the synthesis, an aromatic protectant group for the hydroxyl and the alkyl hydroxy groups of the starting material, removed as the final step of a multi-step synthesis. Such protectant groups yield intermediates which are solid and therefore easily purified at various stages of the process, for an economical and relatively fast process for synthesizing the final product.
    Type: Grant
    Filed: May 30, 2011
    Date of Patent: February 25, 2014
    Assignee: Alphora Research Inc.
    Inventors: Dino Alberico, Boris Gorin, Ryan Beharrilall, Craig Dixon, Joshua Clayton, Varghese Rexon
  • Publication number: 20130338379
    Abstract: Fused cyclopentane—4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A: wherein R represents an aryl group such as p-methoxyphenyl. This compound can be reacted with a lower alkyl aluminum compound to open the dioxalane ring and reduce the lactone to lactol, without over-reducing to diol. The resulting compound can be functionalized to insert chemical side groups of target prostaglandins, adding the required ?-side chain and then the required ?-side chain sequentially and independently of each other. The compounds and process are particularly suitable for preparing lubiprostone.
    Type: Application
    Filed: August 19, 2013
    Publication date: December 19, 2013
    Applicant: Alphora Research Inc.
    Inventors: Dino ALBERICO, Joshua CLAYTON, Boris Ivanovich GORIN, Jan OUDENES
  • Patent number: 8513441
    Abstract: Fused cyclopentane-4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A: wherein R represents an aryl group such as p-methoxyphenyl. This compound can be reacted with a lower alkyl aluminum compound to open the dioxalane ring and reduce the lactone to lactol, without over-reducing to diol. The resulting compound can be functionalized to insert chemical side groups of target prostaglandins, adding the required ?-side chain and then the required ?-side chain sequentially and independently of each other. The compounds and process are particularly suitable for preparing lubiprostone.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: August 20, 2013
    Assignee: Alphora Research Inc.
    Inventors: Dino Alberico, Joshua Clayton, Boris Ivanovich Gorin, Jan Oudenes
  • Publication number: 20130144058
    Abstract: Disclosed is a process for preparing a carbonucleoside of formula (1) and intermediates for use therein. The process involves the step of reacting a compound of formula (2) with a compound of formula (3) under Mitsunobu-type reaction conditions to obtain a compound of formula (4), wherein PG1, PG2, PG3 and PG4 are protecting groups. The compound of formula (4) is deprotected to form the compound of formula (1), as shown below.
    Type: Application
    Filed: May 30, 2011
    Publication date: June 6, 2013
    Applicant: ALPHORA RESEARCH INC.
    Inventors: Dino Alberico, Joshua Clayton, Craig Dixon, Boris Gorin
  • Publication number: 20130066071
    Abstract: Anti-virally active carbanucleosides such as entecavir are prepared by a process which utilizes, throughout the synthesis, an aromatic protectant group for the hydroxyl and the alkyl hydroxy groups of the starting material, removed as the final step of a multi-step synthesis. Such protectant groups yield intermediates which are solid and therefore easily purified at various stages of the process, for an economical and relatively fast process for synthesizing the final product.
    Type: Application
    Filed: May 30, 2011
    Publication date: March 14, 2013
    Applicant: ALPHORA RESEARCH INC.
    Inventors: Dino Alberico, Boris Gorin, Ryan Beharrilall, Craig Dixon, Joshua Clayton, Varghese Rexon
  • Patent number: 8377940
    Abstract: Compounds of Formula (I) wherein R1 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: June 5, 2008
    Date of Patent: February 19, 2013
    Assignee: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Patent number: 8377939
    Abstract: Compounds of Formula I: wherein R1 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: February 19, 2013
    Assignee: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Patent number: 8309744
    Abstract: Fused cyclopentane—4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A: wherein R represents an aryl group such as p-methoxyphenyl. This compound can be reacted with a lower alkyl aluminum compound to open the dioxalane ring and reduce the lactone to lactol, without over-reducing to diol. The resulting compound can be functionalized to insert chemical side groups of target prostaglandins, adding the required ?-side chain and then the required ?-side chain sequentially and independently of each other. The compounds and process are particularly suitable for preparing lubiprostone.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: November 13, 2012
    Assignee: Alphora Research Inc.
    Inventors: Dino Alberico, Joshua Clayton, Boris Ivanovich Gorin, Jan Oudenes
  • Patent number: 8186710
    Abstract: A post-deployment, position-stabilized curtain airbag has a top edge from which an inflatable safety cushion is supported by a vehicle for deployment into a vehicle passenger compartment between occupant and occupant enclosure. A fill chamber is secured to the top edge of the safety cushion. An inflatable structural member is mechanically connected to the safety cushion. The fill chamber directs pressurized gas into the safety cushion and the structural member. The structural member deploys into the passenger compartment between the safety cushion and occupant enclosure limiting outboard displacement of the safety cushion. The structural member fully deploys after the safety cushion. Another structural member deploys along the top edge of the safety cushion limiting pivoting of the safety cushion there relative to the fill chamber. Pressurized gas enters each structural member through auxiliary passageways having oppositely directed entrances and outlets.
    Type: Grant
    Filed: September 14, 2011
    Date of Patent: May 29, 2012
    Assignee: Autoliv ASP, Inc.
    Inventors: Blake L. Cheal, Joshua Clayton Allred
  • Patent number: 8153638
    Abstract: Compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and n are as defined in the description, processes for the preparing the compounds, new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and uses of the compounds in therapy.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: April 10, 2012
    Assignee: AstraZeneca AB
    Inventors: Bradford Van Wagenen, Radhakrishnan Ukkiramapandian, Joshua Clayton, Ian Egle, James R. Empfield, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi, Gary Steelman, Rebecca Urbanek, Sally Walsh
  • Publication number: 20120001407
    Abstract: A post-deployment, position-stabilized curtain airbag has a top edge from which an inflatable safety cushion is supported by a vehicle for deployment into a vehicle passenger compartment between occupant and occupant enclosure. A fill chamber is secured to the top edge of the safety cushion. An inflatable structural member is mechanically connected to the safety cushion. The fill chamber directs pressurized gas into the safety cushion and the structural member. The structural member deploys into the passenger compartment between the safety cushion and occupant enclosure limiting outboard displacement of the safety cushion. The structural member fully deploys after the safety cushion. Another structural member deploys along the top edge of the safety cushion limiting pivoting of the safety cushion there relative to the fill chamber. Pressurized gas enters each structural member through auxiliary passageways having oppositely directed entrances and outlets.
    Type: Application
    Filed: September 14, 2011
    Publication date: January 5, 2012
    Applicant: Autoliv ASP, Inc.
    Inventors: Blake L. Cheal, Joshua Clayton Allred
  • Patent number: 8020888
    Abstract: A post-deployment, position-stabilized curtain airbag has a top edge from which an inflatable safety cushion is supported by a vehicle for deployment into a vehicle passenger compartment between occupant and occupant enclosure. A fill chamber is secured to the top edge of the safety cushion. An inflatable structural member is mechanically connected to the safety cushion. The fill chamber directs pressurized gas into the safety cushion and the structural member. The structural member deploys into the passenger compartment between the safety cushion and occupant enclosure limiting outboard displacement of the safety cushion. The structural member fully deploys after the safety cushion. Another structural member deploys along the top edge of the safety cushion limiting pivoting of the safety cushion there relative to the fill chamber. Pressurized gas enters each structural member through auxiliary passageways having oppositely directed entrances and outlets.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: September 20, 2011
    Assignee: Autoliv ASP, Inc.
    Inventors: Blake L. Cheal, Joshua Clayton Allred
  • Publication number: 20110184192
    Abstract: Fused cyclopentane—4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A: wherein R represents an aryl group such as p-methoxyphenyl. This compound can be reacted with a lower alkyl aluminum compound to open the dioxalane ring and reduce the lactone to lactol, without over-reducing to diol. The resulting compound can be functionalized to insert chemical side groups of target prostaglandins, adding the required ?-side chain and then the required ?-side chain sequentially and independently of each other. The compounds and process are particularly suitable for preparing lubiprostone.
    Type: Application
    Filed: April 7, 2011
    Publication date: July 28, 2011
    Applicant: ALPHORA RESEARCH INC.
    Inventors: Dino ALBERICO, Joshua CLAYTON, Boris Ivanovich GORIN, Jan OUDENES
  • Publication number: 20110166155
    Abstract: The present invention is directed to compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
    Type: Application
    Filed: January 6, 2011
    Publication date: July 7, 2011
    Inventors: Bradford VAN WAGENEN, Radhakrishnan UKKIRAMAPANDIAN, Joshua CLAYTON, Ian EGLE, James R. EMPFIELD, Methvin ISAAC, Fupeng MA, Abdelmalik SLASSI, Gary STEELMAN, Rebecca URBANEK, Sally WALSH