Patents by Inventor Joshua E. Allen

Joshua E. Allen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS RELATING TO TREATMENT OF CANCER
    Publication number: 20150328310
    Abstract: Compositions and methods for treating cancer in a subject in need thereof are provided according to aspects of the present disclosure which include both cetuximab and ISC-4, as a combination formulation or as separate formulations. Methods of treating cancer in a subject in need thereof are provided according to aspects of the present disclosure wherein the subject has cancer characterized by wild-type KRAS wherein the methods include administering a combination of cetuximab and ISC-4 as a combination formulation or separately, and wherein administration of the combination of cetuximab and ISC-4 provides a synergistic anti-cancer effect, treating the cancer.
    Type: Application
    Filed: December 20, 2013
    Publication date: November 19, 2015
    Inventors: Joshua E. Allen, Wafik S. El-Deiry, Arun K. Sharma, Shantu G. Amin
  • SMALL MOLECULE TRAIL GENE INDUCTION BY NORMAL AND TUMOR CELLS AS AN ANTICANCER THERAPY
    Publication number: 20150265619
    Abstract: Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating disease, particularly cancer in a subject in need thereof, including a human subject as well as subjects of other species. The compositions have utility in treating brain cancer in a subject in need thereof.
    Type: Application
    Filed: June 8, 2015
    Publication date: September 24, 2015
    Applicant: The Penn State Research Foundation
    Inventors: Wafik S. EL-DEIRY, Joshua E. Allen, Gen Sheng Wu
  • SMALL MOLECULE TRAIL GENE INDUCTION BY NORMAL AND TUMOR CELLS AS AN ANTICANCER THERAPY
    Publication number: 20150202206
    Abstract: Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating disease, particularly cancer in a subject in need thereof, including a human subject as well as subjects of other species. The compositions have utility in treating brain cancer in a subject in need thereof.
    Type: Application
    Filed: July 22, 2014
    Publication date: July 23, 2015
    Applicant: THE PENN STATE RESEARCH FOUNDATION
    Inventors: Wafik S. El-Deiry, Joshua E. Allen, Gen Sheng WU
  • Small molecule trail gene induction by normal and tumor cells as an anticancer therapy
    Patent number: 9072744
    Abstract: Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating disease, particularly cancer in a subject in need thereof, including a human subject as well as subjects of other species. The compositions have utility in treating brain cancer in a subject in need thereof.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: July 7, 2015
    Assignee: THE PENN STATE RESEARCH FOUNDATION
    Inventors: Wafik S. El-Deiry, Joshua E. Allen, Gen Sheng Wu
  • Small molecule trail gene induction by normal and tumor cells as an anticancer therapy
    Patent number: 9061032
    Abstract: Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating disease, particularly cancer in a subject in need thereof, including a human subject as well as subjects of other species. The compositions have utility in treating brain cancer in a subject in need thereof.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: June 23, 2015
    Assignee: The Penn State Research Foundation
    Inventors: Wafik S. El-Deiry, Joshua E. Allen, Gen Sheng Wu
  • 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one, Salts Thereof and Methods of Using the Same in Combination Therapy
    Publication number: 20140335048
    Abstract: This disclosure relates, at least in part, to a method of treatment. In one embodiment, the method of treatment comprises administering to a subject in need of such treatment a first therapeutic agent including compound (1): or a pharmaceutically acceptable salt thereof in combination with a second therapeutic agent, wherein the first therapeutic agent and the second therapeutic agent are administered either simultaneously or sequentially.
    Type: Application
    Filed: July 25, 2014
    Publication date: November 13, 2014
    Applicant: ONCOCEUTICS, INC.
    Inventors: Martin STOGNIEW, Joshua E. ALLEN
  • 7-benzyl-10-(2-methylbenzyl)-2,6,7,8,9,10-hexahydroimidazo[1,2-a]pyrido[4,3-d]pyrimidin-5(3H)-one, Salts thereof And Methods of Using The Same in Combination Therapy
    Publication number: 20140271540
    Abstract: This disclosure relates, at least in part, to a method of treatment. In one embodiment, the method of treatment comprises administering to a subject in need of such treatment a first therapeutic agent including compound (1): or a pharmaceutically acceptable salt thereof in combination with a second therapeutic agent, wherein the first therapeutic agent and the second therapeutic agent are administered either simultaneously or sequentially.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: ONCOCEUTICS, INC.
    Inventors: Martin STOGNIEW, Joshua E. ALLEN
  • SMALL MOLECULE TRAIL GENE INDUCTION BY NORMAL AND TUMOR CELLS AS AN ANTICANCER THERAPY
    Publication number: 20140248264
    Abstract: Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating disease, particularly cancer in a subject in need thereof, including a human subject as well as subjects of other species. The compositions have utility in treating brain cancer in a subject in need thereof.
    Type: Application
    Filed: February 27, 2014
    Publication date: September 4, 2014
    Applicant: The Penn State Research Foundation
    Inventors: Wafik S. El-Deiry, Joshua E. Allen, Gen Sheng Wu
  • Small molecule trail gene induction by normal and tumor cells as an anticancer therapy
    Patent number: 8673923
    Abstract: Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating disease, particularly cancer in a subject in need thereof, including a human subject as well as subjects of other species. The compositions have utility in treating brain cancer in a subject in need thereof.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: March 18, 2014
    Assignee: The Penn State Research Foundation
    Inventors: Wafik S. El-Deiry, Joshua E. Allen, Gen Sheng Wu
  • SMALL MOLECULE TRAIL GENE INDUCTION BY NORMAL AND TUMOR CELLS AS AN ANTICANCER THERAPY
    Publication number: 20120276088
    Abstract: Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating disease, particularly cancer in a subject in need thereof, including a human subject as well as subjects of other species. The compositions have utility in treating brain cancer in a subject in need thereof.
    Type: Application
    Filed: April 30, 2012
    Publication date: November 1, 2012
    Applicant: The Penn State Research Foundation
    Inventors: Wafik S. El-Deiry, Joshua E. Allen, Gen Sheng Wu