Patents by Inventor Joshua Kaplan

Joshua Kaplan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230270719
    Abstract: This application relates generally to certain substituted pyrrolizine compounds, and pharmaceutical compositions which inhibit HBV replication, and methods of making and using them.
    Type: Application
    Filed: November 29, 2022
    Publication date: August 31, 2023
    Inventors: Jinfa Du, Joshua A. Kaplan, Thorsten A. Kirschberg, Tetsuya Kobayashi, Scott E. Lazerwith, Rick Andrew Lee, Jonathan William Medley, Michael L. Mitchell, Philip Anthony Morganelli, Hyung-Jung Pyun, Sophia L. Shevick, Neil H. Squires, William J. Watkins
  • Publication number: 20230212150
    Abstract: The present disclosure relates generally to compounds that bind to Lysophosphatidic Acid Receptor 1 (LPAR1) and act as antagonists of LPAR1. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of LPAR1, including fibrosis and liver diseases such as non-alcoholic steatohepatitis (NASH), interstitial lung disease (ILD), or chronic kidney disease (CKD).
    Type: Application
    Filed: December 6, 2022
    Publication date: July 6, 2023
    Inventors: Brian P. Bestvater, Joshua A. Kaplan, Barton W. Phillips, Kin S. Yang, Anna Zagorska
  • Publication number: 20230212151
    Abstract: The present disclosure relates generally to compounds that bind to Lysophosphatidic Acid Receptor 1 (LPAR1) and act as antagonists of LPAR1. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of LPAR1, including fibrosis and liver diseases such as non-alcoholic steatohepatitis (NASH), interstitial lung disease (ILD), or chronic kidney disease (CKD).
    Type: Application
    Filed: December 6, 2022
    Publication date: July 6, 2023
    Inventors: Brian P. Bestvater, Zhimin Du, Julie Farand, Joshua A. Kaplan, Barton W. Phillips, Doris T. Tang, Chandrasekar Venkataramani, Peiyuan Wang, Kin S. Yang, Anna Zagorska
  • Publication number: 20230079863
    Abstract: Compounds of formula: wherein the variable substituents are defined herein.
    Type: Application
    Filed: March 25, 2022
    Publication date: March 16, 2023
    Inventors: James L. Bachman, Daniel H. Byun, Christopher T. Clark, Petr Jansa, Joshua A. Kaplan, Zachary A. Kasun, Jennifer R. Lo, Megan E. Neubig, Nathaniel H. Stanley, Kirk L. Stevens
  • Patent number: 11593314
    Abstract: An example method can include storing, on a CSM, a first content item and representations of second and third content items, the second content item having content/features enabled by a cloud service and designed for access through a native online application and the third content item having content/features supported by a local application and having additional features designed for access through a cloud service and native online application; when the first content item is invoked, presenting the content/features of the first content item; in response to a request to access the representation of the second or third content item, sending, to a cloud service, a request for the additional features of the third content item or the content/features of the second content item; and based on metadata received from a cloud service, providing the additional features/content of the third content item or the content/features of the second content item.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: February 28, 2023
    Assignee: Dropbox, Inc.
    Inventors: Joshua Kaplan, Jason Terk, Stan Yeung
  • Patent number: 11584738
    Abstract: The present disclosure relates generally to compounds that bind to Lysophosphatidic Acid Receptor 1 (LPAR1) and act as antagonists of LPAR1. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of LPAR1, including fibrosis and liver diseases such as non-alcoholic steatohepatitis (NASH), interstitial lung disease (ILD), or chronic kidney disease (CKD).
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: February 21, 2023
    Assignee: Gilead Sciences, Inc.
    Inventors: Brian P. Bestvater, Zhimin Du, Julie Farand, Joshua A. Kaplan, Barton W. Phillips, Doris T. Tang, Chandrasekar Venkataramani, Peiyuan Wang, Kin S. Yang, Anna Zagorska
  • Publication number: 20230012262
    Abstract: The present disclosure relates generally to compounds that bind to Lysophosphatidic Acid Receptor 1 (LPAR1) and act as antagonists of LPAR1. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of LPAR1, including fibrosis and liver diseases such as non-alcoholic steatohepatitis (NASH), interstitial lung disease (ILD), or chronic kidney disease (CKD).
    Type: Application
    Filed: May 13, 2021
    Publication date: January 12, 2023
    Inventors: Brian P. Bestvater, Zhimin Du, Julie Farand, Joshua A. Kaplan, Barton W. Phillips, Doris T. Tang, Chandrasekar Venkataramani, Peiyuan Wang, Kin S. Yang, Anna Zagorska
  • Publication number: 20220411405
    Abstract: The present disclosure relates generally to compounds that bind to Lysophosphatidic Acid Receptor 1 (LPAR1) and act as antagonists of LPAR1. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of LPAR1, including fibrosis and liver diseases such as non-alcoholic steatohepatitis (NASH), interstitial lung disease (TLD), or chronic kidney disease (CKD).
    Type: Application
    Filed: May 10, 2022
    Publication date: December 29, 2022
    Inventors: Brian P. Bestvater, Joshua A. Kaplan, Megan E. Neubig, Kin S. Yang, Anna Zagorska
  • Publication number: 20220204491
    Abstract: The present disclosure relates generally to compounds that bind to FXR and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
    Type: Application
    Filed: November 24, 2021
    Publication date: June 30, 2022
    Inventors: Peter A. Blomgren, Kevin S. Currie, Morin Mae Frick, Elizabeth M. Horstman, Joshua A. Kaplan, Jeffrey E. Kropf, William J. Watkins
  • Patent number: 11290531
    Abstract: The present technology addresses a scenario when a user attempts to create a cloud content item using a file system interface on a client device. The present technology can immediately create a content item that is representative of a cloud content item once the user requests a cloud content item to be created. The content item that is representative of the cloud content item can be created even before the cloud content item itself is created. After the cloud content item is created, the present technology provides a mechanism to relate the content item that this representative of the cloud content item with the actual cloud content item.
    Type: Grant
    Filed: December 4, 2019
    Date of Patent: March 29, 2022
    Assignee: Dropbox, Inc.
    Inventors: Cassandra Beckley, Joshua Kaplan
  • Publication number: 20220055985
    Abstract: Provided is a compound of Formula (I): wherein the variable groups are defined herein.
    Type: Application
    Filed: August 31, 2021
    Publication date: February 24, 2022
    Inventors: Julie FARAND, Joshua A. KAPLAN, Gregory NOTTE, Casey Lockwood OLEN, Michael SANGI, David SPERANDIO
  • Patent number: 11225473
    Abstract: The present disclosure relates generally to compounds that bind to FXR and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: January 18, 2022
    Assignee: Gilead Sciences, Inc.
    Inventors: Peter A. Blomgren, Kevin S. Currie, Morin Mae Frick, Elizabeth M. Horstman, Joshua A. Kaplan, Jeffrey E. Kropf, William J. Watkins
  • Patent number: 11194766
    Abstract: Systems and methods for integrating cloud-based and cloud-backed content items with a content management system are provided. In some examples, a method can include receiving a request to open a content item using a client application at a first client device; detecting that the content item is open at a second client device from a different client application that supports live collaboration; and directing the first client device to an instance of the different client application at the first client device.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: December 7, 2021
    Assignee: Dropbox, Inc.
    Inventors: Joshua Kaplan, Jason Terk, Stan Yeung
  • Patent number: 11194767
    Abstract: Systems and methods for integrating cloud-based and cloud-backed content items with a content management system (CSM) are provided. In some examples, a method can include storing a content item in a shared folder on a CSM, the content item representing a cloud-backed or cloud-based content item associated with a cloud content provider; receiving a request to access the content item in the shared folder; in response to the request, determining, based on permissions configured at the CSM, whether a user account has permissions allowing the user account to access the shared folder or the content item; based on a determination that the user account has permissions, granting the user account access to the content item and providing to the user account a content and features of the content item, the features being supported by the cloud content provider and provisioned at least partly through the cloud content provider.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: December 7, 2021
    Assignee: Dropbox, Inc.
    Inventors: Joshua Kaplan, Jason Terk, Stan Yeung
  • Patent number: 11136290
    Abstract: Provided is a compound of Formula (I): wherein the variable groups are defined herein.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: October 5, 2021
    Assignee: The Liver Company Inc.
    Inventors: Julie Farand, Joshua A. Kaplan, Gregory Notte, Casey Lockwood Olen, Michael Sangi, David Sperandio
  • Publication number: 20210286764
    Abstract: An example method can include storing, on a CSM, a first content item and representations of second and third content items, the second content item having content/features enabled by a cloud service and designed for access through a native online application and the third content item having content/features supported by a local application and having additional features designed for access through a cloud service and native online application; when the first content item is invoked, presenting the content/features of the first content item; in response to a request to access the representation of the second or third content item, sending, to a cloud service, a request for the additional features of the third content item or the content/features of the second content item; and based on metadata received from a cloud service, providing the additional features/content of the third content item or the content/features of the second content item.
    Type: Application
    Filed: June 2, 2021
    Publication date: September 16, 2021
    Inventors: Joshua Kaplan, Jason Terk, Stan Yeung
  • Patent number: 11112941
    Abstract: Systems and methods for creating content items are provided. In some examples, a method can include receiving a user selection of an interface element located in a persistent user interface of an operating system desktop of a client device, displaying, in response to the user selection of the interface element, a set of user options, the set of user options comprising a option to create a content item of a particular type, receiving a user selection of the option to create the content item, and initiating the creation of the content item.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: September 7, 2021
    Assignee: Dropbox, Inc.
    Inventors: Joshua Kaplan, Iris Lin, Stanley Yeung, Cheechee Lin, Graciela Kincaid
  • Patent number: 11100053
    Abstract: An example method can include storing, on a CSM, a first content item and representations of second and third content items, the second content item having content/features enabled by a cloud service and designed for access through a native online application and the third content item having content/features supported by a local application and having additional features designed for access through a cloud service and native online application; when the first content item is invoked, presenting the content/features of the first content item; in response to a request to access the representation of the second or third content item, sending, to a cloud service, a request for the additional features of the third content item or the content/features of the second content item; and based on metadata received from a cloud service, providing the additional features/content of the third content item or the content/features of the second content item.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: August 24, 2021
    Assignee: Dropbox, Inc.
    Inventors: Joshua Kaplan, Jason Terk, Stan Yeung
  • Publication number: 20210251957
    Abstract: This application relates generally to certain substituted pyrrolizine compounds, and pharmaceutical compositions which inhibit HBV replication, and methods of making and using them.
    Type: Application
    Filed: November 4, 2020
    Publication date: August 19, 2021
    Inventors: Jinfa DU, Joshua A. KAPLAN, Thorsten A. KIRSCHBERG, Tetsuya KOBAYASHI, Scott E. LAZERWITH, Rick Andrew LEE, Jonathan William MEDLEY, Michael L. MITCHELL, Philip Anthony MORGANELLI, Hyung-Jung PYUN, Sophia L. SHEVICK, Neil H. SQUIRES, William J. WATKINS
  • Publication number: 20210176312
    Abstract: The present technology addresses a scenario when a user attempts to create a cloud content item using a file system interface on a client device. The present technology can immediately create a content item that is representative of a cloud content item once the user requests a cloud content item to be created. The content item that is representative of the cloud content item can be created even before the cloud content item itself is created. After the cloud content item is created, the present technology provides a mechanism to relate the content item that this representative of the cloud content item with the actual cloud content item.
    Type: Application
    Filed: December 4, 2019
    Publication date: June 10, 2021
    Inventors: Cassandra Beckley, Joshua Kaplan