Abstract: A non-limiting example method for control of fluid ejection from a microfluidic device includes firing a microfluidic ejector of a microfluidic device to expel a fluid from a channel of the microfluidic device. In response to detecting an instance of signal change from an impedance sensor disposed in the channel, the method includes controlling fluid ejection from the microfluidic ejector and capturing an image of the channel with an imaging apparatus. Using the captured image, a determination is made as to whether passage of a cell into the channel is associated with the instance of signal change from the impedance sensor. Based on the determination, the microfluidic ejector may fire to dispense the fluid from the channel into a reservoir.

Abstract: In one example in accordance with the present disclosure, a particle detection system is described. The particle detection system includes a microfluidic channel through which fluid is to flow. The fluid includes particles. The particle detection system also includes a sensing circuit to output a resonant frequency. The sensing circuit includes a pair of electrodes disposed within the microfluidic channel. Contents of a volume between the pair of electrodes changes a capacitance between the pair of electrodes. A change in the capacitance changes the resonant frequency output by the sensing circuit. The particle detection system also includes a controller to determine the contents of the volume based on the resonant frequency.

Abstract: In one example in accordance with the present disclosure, a system is described. The system includes a fluidic die to advance across an ejection path relative to a substrate. The fluidic die includes a channel to contain a portion of a sample fluid, a sensor to detect passage of a particle within the sample fluid into the channel, and an ejection device. The ejection device is to eject the particle. The system also includes a controller. The controller identifies discrete locations along the ejection path as waste sites as the fluidic die advances along the ejection path. This is done by 1) classifying the particle as a target particle or a non-target particle, 2) upon identification of a target particle, ejecting the target particle to a target site of the substrate, and 3) upon identification of a non-target particle, ejecting the non-target particle to a waste site.

Abstract: A system may comprise a voltage upconverter, a universal serial bus (USB) connector to receive an input voltage from a USB port on a computing device, and a microfluidic diagnostic chip communication link to electrically couple the voltage upconverter to a microfluidic diagnostic chip wherein the voltage upconverter is to convert the input voltage to be received by the USB connector to an output voltage sufficient to drive a pump on the microfluidic diagnostic chip. A diagnostic system may comprise a microfluidic diagnostic chip comprising a pump and a voltage upconverter to receive an input voltage from a universal serial bus (USB) port of a computing device and to convert the input voltage into an output voltage that powers activation of the pump.

Abstract: According to an example, a microfluidic apparatus may include a channel, a foyer, in which the foyer is in fluid communication with the channel and in which the channel has a smaller width than the foyer, a sensor to sense a property of a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to determine whether the sensed property of the fluid meets a predetermined condition and to perform a predefined action in response to the sensed property of the fluid meeting the predetermined condition.

Abstract: The present disclosure is drawn to microfluidic chips. The microfluidic chips can include an inflexible material having an elastic modulus of 0.1 gigapascals (GPa) to 450 GPa. A microfluidic channel can be formed within the inflexible material and can connect an inlet and an outlet. A working electrode can be associated with the microfluidic channel and can have a surface area of 1 ?m2 to 60,000 ?m2 within the microfluidic channel. A bubble support structure can also be formed within the microfluidic channel such that the working electrode is positioned to electrolytically generate a bubble that becomes associated with the bubble support structure.

Abstract: According to an example, a microfluidic apparatus may include a fluid slot and a foyer that is in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer. The microfluidic apparatus may also include an electrical sensor to measure a change in an electrical field caused by a particle of interest in a fluid passing through the channel from the fluid slot to the foyer, an actuator to apply pressure onto fluid contained in the foyer, and a controller to receive the measured change in the electrical field from the electrical sensor, determine, from the received change in the electrical field, an electrical signature of the particle of interest, and control the actuator to control movement of the particle of interest based upon the determined electrical signature of the particle of interest.

Abstract: According to an example, a microfluidic apparatus may include a fluid slot, a foyer in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer, a sensor to detect a presence of a particle of interest in a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to receive information from the sensor, determine, from the received information, whether a particle of interest has passed through the channel, and control the actuator to expel fluid in the foyer through the nozzle based upon the determination.

Abstract: A microfluidic coagulation analysis method includes introducing a fluid sample into a measurement device including a pinch point that includes a microfluidic channel of substantially consistent width and height connecting a slot and a chamber. The at least one pinch point permits passage of the fluid sample from the slot to the chamber. The method further includes measuring, with a sensor in or near the pinch point, transits of individual cells in the sample passing through the at least one pinch point, and computing, at least in part with a processor, at least one metric indicative of a time period during which the flow of the sample transitions from substantially fluid flow to substantial cessation of flow.

Abstract: Systems, methods, and computer readable medium to provide patterned layer deposition of liquid types to a plate surface in layers organized in layouts with sites of patterns aligned to a plate origin of the plate surface. At least one layer includes a layout defining a geometric layout of the plate surface.

Abstract: In one example in accordance with the present disclosure, a fluid ejection device is described. The fluid ejection device includes a vertical support and an interface movably coupled to the vertical support. The interface is to receive an ejection head. The fluid ejection device also includes a manual adjustment device associated with the interface to adjust a distance between the interface and a substrate stage.

Abstract: Example implementations relate to a microfluidics sensing system. For example, a microfluidics sensing system may include a portable computing device to execute a microfluidics application, a microfluidic chip coupled to the portable computing device, the microfluidic chip including a microfluidic pumping and sensing region to perform a test on a biologic sample, and a printed circuit board (PCB) on a microfluidic reader to instruct the microfluidic pumping and sensing region to perform the test based on a command received from the microfluidics application.

Abstract: The present disclosure is drawn to microfluidic chips. The microfluidic chips can include an inflexible material having an elastic modulus of 0.1 gigapascals (GPa) to 450 GPa. A microfluidic channel can be formed within the inflexible material and can connect an inlet and an outlet. A working electrode can be associated with the microfluidic channel and can have a surface area of 1 ?m2 to 60,000 ?m2 within the microfluidic channel. A bubble support structure can also be formed within the microfluidic channel such that the working electrode is positioned to electrolytically generate a bubble that becomes associated with the bubble support structure.

Abstract: According to an example, a microfluidic apparatus may include a fluid slot and a foyer that is in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer. The microfluidic apparatus may also include an electrical sensor to measure a change in an electrical field caused by a particle of interest in a fluid passing through the channel from the fluid slot to the foyer, an actuator to apply pressure onto fluid contained in the foyer, and a controller to receive the measured change in the electrical field from the electrical sensor, determine, from the received change in the electrical field, an electrical signature of the particle of interest, and control the actuator to control movement of the particle of interest based upon the determined electrical signature of the particle of interest.

Abstract: According to an example, a microfluidic apparatus may include a channel, a foyer, in which the foyer is in fluid communication with the channel and in which the channel has a smaller width than the foyer, a sensor to sense a property of a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to determine whether the sensed property of the fluid meets a predetermined condition and to perform a predefined action in response to the sensed property of the fluid meeting the predetermined condition.

Abstract: According to an example, a microfluidic apparatus may include a fluid slot, a foyer in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer, a sensor to detect a presence of a particle of interest in a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to receive information from the sensor, determine, from the received information, whether a particle of interest has passed through the channel, and control the actuator to expel fluid in the foyer through the nozzle based upon the determination.

Abstract: Examples herein provide a device. The device includes a testing cassette including: a microfluidic channel connecting an input port at a first end to at least one sensor area at a second end, the channel is to allow a blood sample to flow from the input port to the at least one sensor area; at least two electrodes; and a micro-fabricated integrated sensor, wherein when an electrical potential difference is applied over the blood sample, the sensor is to measure, over a duration of time, an electrical signal passing through the blood sample as the blood sample flows from the input port to the at least one sensor area and begin to coagulate, thereby obtaining a measurement function as a function of time. The device includes a processor to correlate the measurement function to a characteristic of the blood sample.

Abstract: A system and method for managing a microfluidics device. The system includes a microfluidics device; a controller with a first processor which receives outputs from the microfluidics device and provides inputs to the microfluidics device; and a computing device with a second processor and an application program interface (API). The computing device provides instructions to the controller using the API. The instructions are executed by the first processor to produce real-time outputs to the microfluidics device.

Abstract: An apparatus includes a microfluidic passage, a chamber, an inlet connecting the microfluidic passage to the chamber, a sensor proximate the inlet to sense fluid within the inlet, a first nozzle, a first fluid driver to move fluid through the first nozzle to draw fluid across the inlet, a second nozzle, a second fluid driver to move fluid through the second nozzle to draw fluid across the inlet and a controller. The controller sequentially actuates the first fluid driver and the second fluid driver.