Abstract: An airfoil and turbine vanes and vane assemblies incorporating the same. The airfoil has an uncoated profile substantially in accordance with Cartesian coordinate values of X, Y, and Z as set forth in Table 1, carried to four decimal places. The Z values refer to a percentage of the radial span of the airfoil measured radially from a radially outwardly facing surface of the inner platform. The turbine vane includes an inner platform, an outer platform, and an airfoil such as the one discussed above extending radially outward from the inner platform toward the outer platform. And the vane assembly includes an inner platform, an outer platform, and two or more first stage vanes extending from the inner platform to the outer platform. Each of the two or more first stage vanes include an airfoil as discussed above.

Abstract: A user can share (show) multimedia information while simultaneously communicating (telling) with one or more other users over a network. Multimedia information is received from at least one source. The multimedia information may be manually and/or automatically annotated and shared with other users. The multimedia information may be displayed in an integrated live view simultaneously with other modes of communication, such as video, voice, or text. A simultaneous sharing communication interface provides an immersive experience that lets a user communicate via text, voice, video, sounds, music, or the like, with one or more other users while also simultaneously sharing media such as photos, videos, movies, images, graphics, illustrations, animations, presentations, narratives, music, sounds, applications, files, and the like. The simultaneous sharing interface enables a user to experience a higher level of intimacy in their communication with others over a network.

Abstract: Systems and methods to reduce false positives in spam filtering. In one aspect, a method includes automatically generating profiles for persons identified in messages, such as incoming and outgoing e-mails. Messages flagged as spam can be checked against the profile to identify false positives.

Abstract: Disclosed herein is an externally-powered strapping tool that includes a strapping tool assembly configured to perform one or more strapping operations; and an external power source operatively coupled thereto, the external power source being attached to the strapping tool assembly in a substantially immovable manner. Also disclosed herein is a strapping tool assembly that includes one or more strapping tool subassemblies configured to perform one or more strapping operations; a power transfer subassembly operatively coupled to the one or more strapping tool subassemblies, the power transfer subassembly configured to transfer motive power from the external power source to the one or more strapping tool subassemblies; and attachment means configured to releasably attach the strapping tool assembly to the external power source, the attachment means further configured to hold the external power source in a substantially fixed position relative to the strapping tool assembly when the attachment means is engaged.

Abstract: The present invention relates to compounds of Formula I as defined herein, and salts and solvates thereof. (I) The present invention also relates to pharmaceutical compositions comprising compounds of Formula (I), and to compounds of Formula (I) for use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which inhibition of a RAS-effector protein-protein interaction is implicated.

Abstract: A pick-up truck bed includes a plurality of plates longer in a longitudinal direction than in a transverse direction that are assembled together along longitudinally extending edges to a laterally adjacent one of the plates. The plates each include a plurality of supporting structures longitudinally extending along a length of the plates that support the plates on transversely extending cross-members. A left-side plate defines a left wheel housing cutout, a longitudinally extending central plate includes first and second complementary interlocking features on opposite longitudinally extending sides, and a longitudinally extending right-side plate defines a right wheel housing cutout. The left-side plate includes a first interlocking feature and the right-side plate includes a second interlocking feature that each receive one of the complementary interlocking features of the central plate.

Abstract: A tailgate tie down system includes a first plate assembly and a second plate assembly. A strap is connected between each of the first plate assembly and the second plate assembly. In an exemplary method, the strap can be routed through at least one accessory tool before securing the first plate assembly and the second plate assembly within tailgate latch openings. Once the plate assemblies are locked within the latch openings, the accessory tool is also locked relative to the tailgate.

Abstract: A user can share (show) multimedia information while simultaneously communicating (telling) with one or more other users over a network. Multimedia information is received from at least one source. The multimedia information may be manually and/or automatically annotated and shared with other users. The multimedia information may be displayed in an integrated live view simultaneously with other modes of communication, such as video, voice, or text. A simultaneous sharing communication interface provides an immersive experience that lets a user communicate via text, voice, video, sounds, music, or the like, with one or more other users while also simultaneously sharing media such as photos, videos, movies, images, graphics, illustrations, animations, presentations, narratives, music, sounds, applications, files, and the like. The simultaneous sharing interface enables a user to experience a higher level of intimacy in their communication with others over a network.

Abstract: A strapping tensioning and sealing tool is disclosed herein. In one or more embodiments, the strapping tensioning and sealing tool includes a tensioning assembly, the tensioning assembly configured to apply tension to a piece of strapping; and a sealing assembly, the sealing assembly comprising at least one cam member, at least one crimping jaw member, and a motive power source, the at least one cam member operatively coupling the at least one crimping jaw member to the motive power source, and the at least one crimping jaw member of the sealing assembly configured to crimp a strapping sealing member so as to secure the piece of strapping around a package or bundle of items.

Abstract: Processes for preparing oxycodone are provided. Said processes encompass a step which is a hydrogenation of an 14-hydroxycodeinone salt in the presence of trifluoroacetic acid and/or a glycol.

Abstract: The present invention relates to influenza A virus variants, particularly variants that are resistant to a polymerase inhibitors. Also provided are methods and compositions related to the influenza A virus variants. Further provided are methods of isolating, identifying, and characterizing multiple viral variants from a patient.

Abstract: The present invention relates to influenza A virus variants, particularly variants that are resistant to a polymerase inhibitors. Also provided are methods and compositions related to the influenza A virus variants. Further provided are methods of isolating, identifying, and characterizing multiple viral variants from a patient.

Abstract: An externally-powered strapping tool includes a strapping tool assembly configured to perform one or more strapping operations; and an external power source operatively coupled thereto, the external power source being attached to the strapping tool assembly in a substantially immovable manner. According to another aspect, a strapping tool assembly includes one or more strapping tool subassemblies configured to perform one or more strapping operations; a power transfer subassembly operatively coupled to the one or more strapping tool subassemblies, the power transfer subassembly configured to transfer motive power from an external power source to the one or more strapping tool subassemblies; and a coupling member configured to couple the strapping tool assembly to the external power source.

Abstract: Disclosed are systems and methods for improving interactions with and between computers in content providing, searching and/or hosting systems supported by or configured with devices, servers and/or platforms. The disclosed systems and methods provide a framework for delivering electronic messages to a recipient in an optimized manner based on current real-world and digital activities associated with the recipient. Once a message sent by a sender is received by the message platform, the message and information related to a user's activity is analyzed, and a delivery condition is determined by the messaging platform. The platform then sends the message according to that delivery condition, such that it is delivered to the user only upon the platform relaying the message thereon when the condition is satisfied or occurs.