Abstract: A semiconductor device includes a first cell. The first cell includes a first functional feature, a first sensitivity region, at least one anchor node, wherein each of the at least one anchor node is different from the first functional feature, and a number of anchor nodes of the at least one anchor node linked to the first functional feature is based on a position of the first functional feature relative to the first sensitivity region. The semiconductor device further includes a second cell abutting the first cell. The second cell includes a second functional feature, wherein the second functional feature satisfies a minimum spacing requirement with respect to the first functional feature.

Abstract: Compounds of formula (I) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6:

Abstract: A method for making an LED lighting fixture includes the steps of: a) cutting a flat blank to form a flat plate including a central piece having a central region and a circumferential region, and a plurality of peripheral extensions; b) forming on the flat plate a patterned circuit which includes a plurality of electrical contact pairs that are formed on the central piece or the peripheral extensions; c) bringing a plurality of LED dies into electrical contact with the electrical contact pairs, respectively; and d) bending the peripheral extensions rearwardly relative to the central piece and toward the central axis to form a shell.

Abstract: Oxindole compounds useful for the treatment of CCR(9) mediated conditions or diseases are provided.

Abstract: A display substrate includes a base substrate with a display area and a light-blocking area around the display area, a switching element disposed on the base substrate that includes a gate electrode electrically connected to a gate line extending in a first direction, a source electrode electrically connected to a data line extending in a second direction crossing the first direction, and a drain electrode spaced apart from the source electrode, a color filter layer disposed on the switching element, a first electrode disposed on the color filter layer, an insulation layer disposed on the first electrode, a second electrode disposed on the insulation layer that includes a slit, a dummy pattern disposed on substantially the same layer as the second electrode that overlaps the data line, and a data light-blocking pattern directly disposed on the dummy pattern that has substantially the same width as the data line.

Abstract: A standard cell for a semiconductor device includes a plurality of features for performing the functionality of the standard cell. The standard cell further includes a first sensitivity region adjacent to a first edge of the standard cell. The standard cell further includes anchor nodes linked to corresponding features of the plurality of features, wherein a number of anchor nodes linked to each feature of the corresponding features is based on a position of an end of each feature of the corresponding features relative to the first sensitivity region.

Abstract: Compounds are provided that are modulators of the C5a receptor. The compounds are substituted piperidines and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activation of C5a receptors.

Abstract: Benzimidazole, benzopyrazole and benzotriazole compounds are provided which bind to CCR(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection and cancer.

Abstract: Compounds are provided as inhibitors of CXCR2, having the structure:

Abstract: Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (II): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: Oxindole compounds useful for the treatment of CCR(9) mediated conditions or diseases are provided.

Abstract: Aniline compounds are provided which bind to CCR(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection and cancer.

Abstract: A method including decomposing a conflict graph based on a number of masked to be used to manufacture a semiconductor device. The method further includes determining whether the decomposed conflict graph is a simplified graph based on a comparison between the decomposed conflict graph and a stored conflict graph. The method further includes determining whether the decomposed conflict graph is colorable based on a number of masks used to pattern the layer of the semiconductor device. The method further includes indicating that the conflict graph is colorable in response to a determination that the decomposed conflict graph is colorable.

Abstract: An electrical connector is used to mate with a mating connector. The mating connector includes multiple mating terminals, and each mating terminal has a first contact portion. The electrical connector includes: an insulating body having a mating space used to mate with the mating connector; a shielding sheet accommodated in the insulating body; multiple contact terminals, each being accommodated in the insulating body and located at one side of the shielding sheet, and each has a second contact portion exposed to the mating space; and an elastic body accommodated in the insulating body and partially exposed to the mating space. The elastic body is located between the shielding sheet and the contact terminals. When the electric connector is mated with the mating connector, the first contact portions enters into the mating space, and the elastic body forces each first contact portion abuts a corresponding second contact portion.

Abstract: An integrated circuit includes a first and second set of gate structures. A center of each of the first set of gate structures is separated from a center of an adjacent gate of the first set of gate structures in a first direction by a first pitch. A center of each of the second set of gate structures is separated from a center of an adjacent gate of the second set of gate structures in the first direction by the first pitch. The first and second set of gate structures extend in a second direction. A gate of the first set of gate structures is aligned in the second direction with a corresponding gate of the second set of gate structures. The gate of the first set of gate structures is separated from the corresponding gate of second set of gate structures in the second direction by a first distance.

Abstract: A method of manufacturing an integrated circuit includes generating a layout design of the integrated circuit, manufacturing the integrated circuit based on the layout design, and removing a portion of a gate structure of a set of gate structures thereby forming a first and a second gate structure. Generating the layout design includes placing a set of gate layout patterns and a cut feature layout pattern on the first layout level. The cut feature layout pattern extends in a first direction, overlaps the set of gate layout patterns and identifies a location of the portion of the gate structure of the set of gate structures. The set of gate layout patterns correspond to fabricating a set of gate structures. The set of gate layout patterns extending in a second direction and overlapping a set of gridlines that extend in the second direction.

Abstract: The present disclosure is drawn to the combination therapy of a C—C Chemokine Receptor 4 (CCR4) antagonist and one or more immune checkpoint inhibitors in the treatment of cancer.

Abstract: Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: Compounds are provided as chemokine inhibitors having the structure:

Abstract: A method of determining colorability of a layer of a semiconductor device includes iteratively decomposing a conflict graph to remove all nodes having fewer links than a threshold number of links. The method further includes determining whether the decomposed conflict graph is a simplified graph based on a comparison between the decomposed conflict graph and a stored conflict graph. The method further includes determining whether the decomposed conflict graph is colorable based on a number of masks used to pattern the layer of the semiconductor device. The method further includes flagging violations in response to a determination that the decomposed conflict graph is not colorable.