Abstract: An electrical connecting portion for a device with a heating function is a portion of a heating unit of the device. The electrical connecting portion includes a substrate, two copper layers, and two electrically conductive coating layers. The substrate is made of a light-transmittable material and includes a front face and a rear face. Each of the two copper layers includes at least one first through-hole extending in a front-rear direction. Each of the two electrically conductive coating layers substantially covers a respective one of the two copper layers and is coupled to the front face of the substrate. Each of the two electrically conductive coating layers substantially fills the at least one first through-hole of the respective one of the two copper layers. The two electrically conductive coating layers have an insulating spacing therebetween. Thus, the electrical connecting portion prevents hot melting and provides better electrical connection reliability.

Abstract: A portable genome sequencing and genotyping device includes a sample processing module, a sequencing module, an analyzing module, and a communication module. The sample processing module is configured to process a sample so as to generate at least one DNA segment of the sample. The sequencing module is connected to the sample processing module, and is configured to generate a number of base sequences corresponding to the at least one DNA segment. The analyzing module is coupled to the sequencing module, and is configured to generate a genotyping analysis result based on the base sequences. The communication module is configured to receive the genotyping analysis result and transmit the genotyping analysis result to a user terminal.

Abstract: A method for establishing robust prediction model is adapted for solving the problem that the conventional prediction model cannot generate stable and credible results with missing data. The method of the present invention includes the following steps: obtaining pre-established single-modality standard models respectively based on each type of modalities from samples; extracting modality sets each having the same modality types from the samples to establish corresponding multi-modalities standard models; extracting multiple combinations of the modality sets from the samples having complete modalities to be training data, wherein the multiple combinations of the modality sets can be classified into single-modality, multi-modalities and complete-modalities; inputting said training data into a to-be trained prediction model, and modifying the prediction model by said single-modality standard models and said multi-modalities standard models to obtain a well-trained prediction model.

Abstract: An automated pathogenic mutation classification method is provided, which includes producing a population score using a population database based on related information. A variant type score is produced using a variation pattern prediction tool based on the related information. A clinical score is produced using the related information or a clinical database based on the related information. A functional score is produced using a functional variant hazard prediction tool based on the related information. The population score, the variant type score, the clinical score, and the functional score are summed to obtain a pathogenic score. Probability that mutation sites suffer from a corresponding disease is determined based on the pathogenic score. When the pathogenic score is higher, the probability of the mutation sites suffering from the corresponding disease is higher.

Abstract: A data processing system can be operated in one of a preprocessing mode, a short-read mapping mode, a sequence assembly mode or a variant calling mode that are related to a to-be-tested DNA sequence. The data processing system includes a sorting engine that supports high-speed processing of sorting in the preprocessing mode and the sequence assembly mode, and a dynamic processing engine that supports dynamic programming calculations in the short-read mapping mode and the variant calling mode. The data processing system may be implemented on a system-on-chip (SoC) for performing accelerated processing of gene sequencing data with reduced memory requirements.

Abstract: A manufacturing method of an image sensor including the following steps is provided. A substrate is provided. A light sensing device is formed in the substrate. A storage node is formed in the substrate. The storage node and the light sensing device are separated from each other. A buried gate structure is formed in the substrate. The buried gate structure includes a buried gate and a first dielectric layer. The buried gate is disposed in the substrate and covers at least a portion of the storage node. The first dielectric layer is disposed between the buried gate and the substrate. A first light shielding layer is formed on the buried gate. The first light shielding layer is located above the storage node and electrically connected to the buried gate.

Abstract: A vehicle lamp includes a housing including a compartment having an opening. A reflective unit and a lighting unit are mounted in the compartment. The lighting unit includes a first circuit board and a first LED. A lens is mounted to a front end of the housing and covers the opening of the compartment. The reflective unit reflects light rays from the first LED to transmit through the lens. A heating unit includes a substrate made of a light transmittable material and a heating layer disposed on the substrate. A sensor is mounted in the compartment for detecting temperature. When the detected temperature is lower than a first predetermined temperature, the heating layer is activated to proceed with an electrical heating operation. When the detected temperature is higher than a second predetermined temperature, the electrical heating operation of the heating layer is stopped or gradually reduced.

Abstract: A method for DNA sequence alignment is proposed to include steps of: generating multiple strings by acquiring foremost k number of suffixes corresponding to a reference DNA sequence; grouping the strings into multiple string groups; sorting the strings in each of the string groups to generate sorting results; obtaining sorted suffixes and a suffix array based on the sorting results; establishing FM-index data based on the sorted suffixes and the suffix array; and performing DNA sequence alignment on a target string based on the FM-index data to obtain an alignment result.

Abstract: An electrical connecting portion for a device with a heating function is a portion of a heating unit of the device. The electrical connecting portion includes a substrate, two copper layers, and two electrically conductive coating layers. The substrate is made of a light-transmittable material and includes a front face and a rear face. Each of the two copper layers includes at least one first through-hole extending in a front-rear direction. Each of the two electrically conductive coating layers substantially covers a respective one of the two copper layers and is coupled to the front face of the substrate. Each of the two electrically conductive coating layers substantially fills the at least one first through-hole of the respective one of the two copper layers. The two electrically conductive coating layers have an insulating spacing therebetween. Thus, the electrical connecting portion prevents hot melting and provides better electrical connection reliability.

Abstract: A text comparison method is adapted for comparing a query file with an existing file. The text comparison method includes: converting the existing file, by an irreversible method, to obtain a first intermediate file, wherein the first intermediate file includes a plurality of characters, and a number of different characters of the plurality of characters is a predetermined value; receiving a second intermediate file which is a file converted from the query file by the irreversible method; and according to a predetermined string length, comparing the second intermediate file with the first intermediate file by a high repeating-character comparison method to output a comparison result. Therefore, the second intermediate file can be created offline and then only the second intermediate file but not the original query file is submitted through internet for private text comparison.

Abstract: A portable genome sequencing and genotyping device includes a sample processing module, a sequencing module, an analyzing module, and a communication module. The sample processing module is configured to process a sample so as to generate at least one DNA segment of the sample. The sequencing module is connected to the sample processing module, and is configured to generate a number of base sequences corresponding to the at least one DNA segment. The analyzing module is coupled to the sequencing module, and is configured to generate a genotyping analysis result based on the base sequences. The communication module is configured to receive the genotyping analysis result and transmit the genotyping analysis result to a user terminal.

Abstract: A vehicle lamp includes a housing including a compartment having an opening. A reflective unit and a lighting unit are mounted in the compartment. The lighting unit includes a first circuit board and a first LED. A lens is mounted to a front end of the housing and covers the opening of the compartment. The reflective unit reflects light rays from the first LED to transmit through the lens. A heating unit includes a substrate made of a light transmittable material and a heating layer disposed on the substrate. A sensor is mounted in the compartment for detecting temperature. When the detected temperature is lower than a first predetermined temperature, the heating layer is activated to proceed with an electrical heating operation. When the detected temperature is higher than a second predetermined temperature, the electrical heating operation of the heating layer is stopped or gradually reduced.

Abstract: A manufacturing method of an image sensor including the following steps is provided. A substrate is provided. A light sensing device is formed in the substrate. A storage node is formed in the substrate. The storage node and the light sensing device are separated from each other. A buried gate structure is formed in the substrate. The buried gate structure includes a buried gate and a first dielectric layer. The buried gate is disposed in the substrate and covers at least a portion of the storage node. The first dielectric layer is disposed between the buried gate and the substrate. A first light shielding layer is formed on the buried gate. The first light shielding layer is located above the storage node and electrically connected to the buried gate.

Abstract: An image sensor including a substrate, a light sensing device, a storage node, a buried gate structure, and a first light shielding layer is provided. The light sensing device is disposed in the substrate. The storage node is disposed in the substrate. The storage node and the light sensing device are separated from each other. The buried gate structure includes a buried gate and a first dielectric layer. The buried gate is disposed in the substrate and covers at least a portion of the storage node. The first dielectric layer is disposed between the buried gate and the substrate. The first light shielding layer is disposed on the buried gate and is located above the storage node. The first light shielding layer is electrically connected to the buried gate.

Abstract: A text comparison method is adapted for comparing a query file with an existing file. The text comparison method includes: converting the existing file, by an irreversible method, to obtain a first intermediate file, wherein the first intermediate file includes a plurality of characters, and a number of different characters of the plurality of characters is a predetermined value; receiving a second intermediate file which is a file converted from the query file by the irreversible method; and according to a predetermined string length, comparing the second intermediate file with the first intermediate file by a high repeating-character comparison method to output a comparison result. Therefore, the second intermediate file can be created offline and then only the second intermediate file but not the original query file is submitted through interne for private text comparison.

Abstract: A microarray including a plurality of detection areas and at least one mark is provided. The plurality of the detection areas are arranged in an array. The at least one mark is disposed among or beside the plurality of the detection areas. The at least one mark is configured for at least one of image focusing, positioning and splicing, wherein the at least one mark comprises a plurality of grid dots distributed in an area. The area comprises a plurality of zones arranged in an array, each of the plurality of the grid dots is disposed in one of the plurality of the zones, a number of the plurality of the grid dots is less than a number of the plurality of the zones, and the plurality of the grid dots form a two-dimensional pattern.

Abstract: An image sensor including a substrate, a light sensing device, a storage node, a buried gate structure, and a first light shielding layer is provided. The light sensing device is disposed in the substrate. The storage node is disposed in the substrate. The storage node and the light sensing device are separated from each other. The buried gate structure includes a buried gate and a first dielectric layer. The buried gate is disposed in the substrate and covers at least a portion of the storage node. The first dielectric layer is disposed between the buried gate and the substrate. The first light shielding layer is disposed on the buried gate and is located above the storage node. The first light shielding layer is electrically connected to the buried gate.

Abstract: A microarray including a plurality of detection areas and at least one mark is provided. The plurality of the detection areas are arranged in an array. The at least one mark is disposed among or beside the plurality of the detection areas. The at least one mark is configured for at least one of image focusing, positioning and splicing, wherein the at least one mark comprises a plurality of grid dots distributed in an area. The area comprises a plurality of zones arranged in an array, each of the plurality of the grid dots is disposed in one of the plurality of the zones, a number of the plurality of the grid dots is less than a number of the plurality of the zones, and the plurality of the grid dots form a two-dimensional pattern.

Abstract: A method for DNA sequence alignment is proposed to include steps of: generating multiple strings by acquiring foremost k number of suffixes corresponding to a reference DNA sequence; grouping the strings into multiple string groups; sorting the strings in each of the string groups to generate sorting results; obtaining sorted suffixes and a suffix array based on the sorting results; establishing FM-index data based on the sorted suffixes and the suffix array; and performing DNA sequence alignment on a target string based on the FM-index data to obtain an alignment result.

Abstract: A vehicular lamp includes a housing having a chamber. The housing includes a heat dissipating portion made of metal. The housing further includes a platform integrally formed with the heat dissipating portion. The platform includes a coupling portion. A reflective cover is mounted in the chamber and includes a recessed portion in. The recessed portion has a rear end with an opening. The platform extends through the opening, and the coupling portion is received in the recessed portion. The recessed portion includes a reflective face. A light-emitting diode unit includes a plurality of light-emitting diodes fixed to the coupling portion and a circuit board fixed to the coupling portion. The light-emitting diodes emit light rays towards the reflective face of the reflective cover. A shield is mounted in front of the housing and is transmittable to the light rays.