Patents by Inventor Julie F. Liu

Julie F. Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100120786
    Abstract: This invention relates to novel compounds that are piperazine derivatives, and pharmaceutically acceptable salts thereof. More specifically, the invention relates to novel piperazine compounds that are derivatives of the chemokine CCR5 receptor antagonist, vicriviroc. This invention also provides pyrogen-free compositions comprising one or more compounds of the invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are treated by administering chemokine CCR5 receptor antagonists, such as vicriviroc. The invention also relates to the use of one or more of the disclosed compounds as reagents in analytical studies involving vicriviroc.
    Type: Application
    Filed: October 21, 2009
    Publication date: May 13, 2010
    Applicant: CoNCERT Pharmaceuticals, Inc.
    Inventors: Julie F. Liu, Rose A. Persich├Ętti
  • Publication number: 20100076010
    Abstract: This invention relates to novel compounds that are dihydroindoles derivatives and pharmaceutically acceptable salts thereof. More specifically, this invention relates to novel dihydroindoles derivatives that are derivatives of silodosin. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering an ?-1A-adrenoreceptor antagonist, such as silodosin.
    Type: Application
    Filed: August 31, 2009
    Publication date: March 25, 2010
    Inventor: Julie F. Liu
  • Publication number: 20100004340
    Abstract: This disclosure relates to novel melatonin analogues or naphthyl(ethyl)acetamides, their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a dual melatoninergic agonist and serotoninergic antagonist.
    Type: Application
    Filed: September 21, 2009
    Publication date: January 7, 2010
    Applicant: CONCERT PHARMACEUTICALS, INC.
    Inventors: Julie F. Liu, Roger Tung
  • Publication number: 20090270336
    Abstract: This invention relates to novel compounds that are piperazine derivatives, and pharmaceutically acceptable salts thereof. More specifically, the invention relates to novel piperazine compounds that are derivatives of the chemokine CCR5 receptor antagonist, vicriviroc. This invention also provides pyrogen-free compositions comprising one or more compounds of the invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are treated by administering chemokine CCR5 receptor antagonists, such as vicriviroc. The invention also relates to the use of one or more of the disclosed compounds as reagents in analytical studies involving vicriviroc.
    Type: Application
    Filed: April 17, 2009
    Publication date: October 29, 2009
    Applicant: CoNCERT Pharmaceuticals, Inc.
    Inventors: Julie F. Liu, Rose Persichetti
  • Patent number: 7608737
    Abstract: This disclosure relates to novel melatonin analogues or naphthyl(ethyl)acetamides, their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a dual melatoninergic agonist and serotoninergic antagonist.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: October 27, 2009
    Assignee: Concert Pharmaceuticasl Inc.
    Inventors: Julie F. Liu, Roger Tung
  • Publication number: 20090239886
    Abstract: This invention relates to novel compounds that are substituted xanthine derivatives and pharmaceutically acceptable salts thereof. For example, this invention relates to novel substituted xanthine derivatives that are derivatives of pentoxifylline. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions for which pentoxifylline and related compounds are beneficial.
    Type: Application
    Filed: February 27, 2009
    Publication date: September 24, 2009
    Applicant: CoNCERT Pharmaceuticals, Inc.
    Inventors: Roger D. Tung, Julie F. Liu, Scott L. Harbeson
  • Publication number: 20090176744
    Abstract: This invention relates to novel compounds that are deuterated derivatives of fingolimod and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering a lysophospholipid edg1 (S1P1) receptor agonist, such as fingolimod.
    Type: Application
    Filed: October 31, 2008
    Publication date: July 9, 2009
    Applicant: CoNCERT Pharmaceuticals, Inc.
    Inventors: Julie F. Liu, Rose A. Persichetti
  • Publication number: 20090149544
    Abstract: This invention relates to novel alpha-aminoamide derivatives, their pharmaceutically acceptable salts, solvates, and hydrates thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering an inhibitor of monoamine oxidase type B (MAO-B) and/or a sodium (Na+) channel blocker, and/or a calcium (Ca2+) channel modulator.
    Type: Application
    Filed: October 22, 2008
    Publication date: June 11, 2009
    Applicant: CoNCERT Pharmaceuticals, Inc.
    Inventor: Julie F. Liu
  • Publication number: 20090143363
    Abstract: This invention relates to novel compounds that are 3-benzazepine derivatives and pharmaceutically acceptable salts thereof. More specifically, this invention relates to novel 3-benzazepine derivatives that are derivatives of lorcaserin. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering a 5-HT2C agonist, such as lorcaserin.
    Type: Application
    Filed: October 15, 2008
    Publication date: June 4, 2009
    Applicant: CoNCERT Pharmaceuticals, Inc.
    Inventor: Julie F. Liu
  • Publication number: 20090131485
    Abstract: This invention relates to novel substituted pyridinones, their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a TNF (tumor necrosis factor)-alpha production inhibitor/TGF (transforming growth factor)-beta inhibitor.
    Type: Application
    Filed: September 10, 2008
    Publication date: May 21, 2009
    Applicant: CoNCERT Pharmaceuticals, Inc.
    Inventors: Julie F. Liu, Yong Dong
  • Publication number: 20090042842
    Abstract: This invention relates to novel compounds which are derivatives of the phosphodiesterase inhibitor, cilostazol and pharmaceutically acceptable salts thereof. This invention also provides pyrogen-free compositions comprising one or more compounds of the invention and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are treated by administration of an phosphodiesterase inhibitor, such as cilostazol. The invention also relates to the use of the disclosed compounds and compositions as reagents in analytical studies involving cilostazol.
    Type: Application
    Filed: April 24, 2008
    Publication date: February 12, 2009
    Applicant: CoNCERT Pharmaceuticals, Inc.
    Inventors: Julie F. Liu, Rose A. Persichetti
  • Publication number: 20090012112
    Abstract: This invention relates to novel compounds that are dihydroindoles derivatives and pharmaceutically acceptable salts thereof. More specifically, this invention relates to novel dihydroindoles derivatives that are derivatives of silodosin. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering an ?-1A-adrenoreceptor antagonist, such as silodosin.
    Type: Application
    Filed: February 26, 2008
    Publication date: January 8, 2009
    Inventor: Julie F. Liu
  • Publication number: 20080280908
    Abstract: This disclosure relates to novel melatonin analogues or naphthyl(ethyl)acetamides, their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a dual melatoninergic agonist and serotoninergic antagonist.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 13, 2008
    Applicant: CONCERT PHARMACEUTICALS INC.
    Inventors: Julie F. Liu, Roger Tung
  • Publication number: 20080261926
    Abstract: This invention relates to novel calcimimetic compounds, their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by binding to, and modulating the sensitivity of, calcium receptors on the parathyroid gland.
    Type: Application
    Filed: April 1, 2008
    Publication date: October 23, 2008
    Inventors: Julie F. Liu, Jillian Imagire