Abstract: Example optical components, optical systems, and lidars are provided. One example optical component includes at least one rotationally symmetric aspherical lens, and at least one rotationally symmetric spherical lens or at least one non-rotationally symmetric cylindrical lens, and the optical component is configured to shape a laser beam emitted by a laser, and a quantity of lenses in the optical component is less than or equal to 3.

Abstract: The invention relates to compounds that interact with heparanase, uses in heparanase screening, uses in in vitro and in vivo imaging (e.g., positron emission tomography (PET) and magnetic resonance imaging (MRI)), methods of synthesis, methods of modulating heparanase activity, and methods of treating disease and disorders associated with heparanase. The compounds of the invention are also useful in treating one or more diseases or disorders associated with the function of heparanase.

Abstract: A request processing method and system are provided. The request processing method is applied to the request processing system. The system comprises an allocation node and at least two task processing nodes, and the method comprises: by the allocation node, receiving at least two to-be-processed requests, and receiving task response messages sent by the at least two task processing nodes, where each of the task response messages carries a task processing weight, and allocating, based on the task processing weight and the at least two to-be-processed requests, a corresponding to-be-processed request set to a first task processing node; and by the first task processing node, performing task processing on one or more to-be-processed requests in a received to-be-processed request set, updating the task processing weight according to current processing state information during the performing task processing, and sending the updated task processing weight to the allocation node.

Abstract: A composition of matter for treating inflammatory bowel diseases (IBDs) and a corresponding method for treating IBDs. The composition of matter includes a reactive oxygen species (ROS) scavenger conjugated to a probiotic. The method includes administering the composition of matter to a subject in an anti-IBD-effective amount.

Abstract: A key-value cache data conversion method includes obtaining source key-value cache data extracted from a source graphics processing unit (GPU), and partitioning and adjusting data format of the source key-value cache data based on mapping information between the source GPU and a target GPU to obtain target key-value cache data that matches processing capability of the target GPU.

Abstract: Systems, methods, and software are disclosed herein for providing an audible notification of the status of IMS service of a non-terrestrial cell in various implementations. In one example, a method of operating a computing device includes receiving a service information block from a non-terrestrial cell hosting a current session of network data service to the computing device; processing a service time parameter of the service information block to determine a notification time for a voice call; and enabling an audible notification on the computing device at the notification time.

Abstract: Example detection apparatus, example lidars, and example terminals are provided. One example detection apparatus includes a transmitter, a receiver, and an isolation buffer member, where the transmitter and the receiver form an off-axis architecture. The transmitter is configured to emit detection light, where the detection light is propagated to the outside of the detection apparatus through an optical element. The receiver is configured to receive return light of the detection light from the outside of the detection apparatus, where the return light passes through the optical element. The isolation buffer member is disposed inside the detection apparatus. The isolation buffer member is made of a flexible material, and the isolation buffer member is disposed between a main optical path of the detection light and a main optical path of the return light.

Abstract: Provided is a stable high-concentration self-buffering pharmaceutical composition, comprising a VEGF binding molecule, a stabilizer, a surfactant, and the like. The pH of the composition is 5.0-7.0. The pharmaceutical composition features no additionally added buffering agent, very high stability, convenient storage, and wide application prospects.

Abstract: In various examples, techniques for generating vocabulary dictionary for localization in autonomous and/or semi-autonomous systems and applications are described herein. Systems and methods may use multiple clustering techniques—such as K-Means Clustering and/or Balanced Iterative Reducing and Clustering using Hierarchies (BIRCH)—to initially generate and/or update a vocabulary dictionary corresponding to an environment. For instance, using the clustering techniques, extracted features from initial images of a localization map may be used to generate a vocabulary tree corresponding to the vocabulary dictionary. Additionally, and again using the clustering techniques, extracted features from new images of the localization map may be used to update the vocabulary tree.

Abstract: In various examples, stereo image localization for autonomous and/or semi-autonomous systems and applications is described herein. Systems and methods may perform localization using two images from a stereo camera along with a map image from a localization map. For instance, a respective relative pose between each of the images and the map image may be determined along with a relative pose between the images. The relative poses may then be used to determine a predicted pose—such as an estimated rotation and/or an estimated translation—between one of the images and the map image. Additionally, the predicted pose may be refined using one or more optimization techniques, such as by minimizing distances between feature points of the images and epipolar lines associated with the points. The refined pose between the images may then be used to determine a localized pose of the machine within the environment.

Abstract: Antibodies, chimeric antigen receptors (CARs) and other molecules that specifically bind ENPP3 are provided. Host cells, such as immune cells, including the molecules, antibodies, fusion proteins, CARs, nucleic acids encoding them, are also provided. In some forms, the cells are CAR immune cells. In some forms, the CAR immune cells maintain the ability to kill ENPP3+ cancer cells after multiple stimulations. Pharmaceutical compositions including the antibodies, CARs or T cells are also provided. In some forms, the molecule or antibody includes drugs conjugated thereto, has antibody-dependent cell-mediated cytotoxicity (ADCC) activity, complement-dependent cytotoxicity activity (CDC), and/or is a bi-specific engager optionally a T cell engager or NK cell engager. Methods of using the described molecules to treat ENPP3+ cancers are also described.

Abstract: The present invention discloses a discontinuous pulse width modulation method, including: shifting an obtained first three-phase modulation wave upwards and downwards to obtain an upward-shifted three-phase modulation wave, a down-shifted three-phase modulation wave, an upward-shifted zero-sequence component and a down-shifted zero-sequence component; calculating a start time-point of a transition interval, a target zero-sequence component within a transition interval and an end time-point of a transition interval based on the above modulation wave and its zero-sequence component; adding the first three-phase modulation wave and the target zero-sequence component together to obtain a target three-phase modulation wave.

Abstract: Disclosed are salts of N-Cyclopentyl-5-(2-((5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)amino)-5-fluoropyrimidin-4-yl)-4-methylthiazol-2-amine and polymorphs thereof, which are inhibitors of protein kinases, in particular cyclin-dependent kinase 4/6 (CDK4/6), and can be used to treat proliferative disorders, such as cancer, and other diseases related to protein kinase/CDK activity. The disclosure includes the succinate salt of N-cyclopentyl-5-(2-((5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)amino)-5-fluoropyrimidin-4-yl)-4-methylthiazol-2-amine, Crystal Form A of the succinate salt, a pharmaceutical formulation comprising the succinate salt, and use of the succinate salt to treat the proliferative disorders.

Abstract: A monitoring system and a monitoring method for a concrete face rockfill dam on a deep overburden layer based on multi-source monitoring information are provided by the present application. In the present application, the data of various dimensions are collected and analyzed in real time at multiple positions and in multiple dimensions, covering all construction positions of the dam foundation, the dam slope, and the dam body, including various monitoring results of the stress field, the displacement field, and the rupture field, comprehensive detection from local to organized, from surface to interior is achieved. The joint analysis of the monitoring data from the multiple positions avoids limitations of only analyzing a single position of the dam at present, the most comprehensive monitoring data is provided, which is conducive to understanding status and changing trends of the dam construction process.

Abstract: The present invention relates to a polyol component (A) comprising at least one polyacrylate polyol (A1), crosslinkable composition comprising the polyol component (A), and its use in coatings. More particularly, the polyol component (A) comprises at least one polyacrylate polyol (A1) obtained from monomers of hydroxyalkyl(meth)acrylate monomers (a1) and (substituted) cycloaliphatic (meth)acrylate monomers (a4), the polyacrylate polyol (A1) having a Mn of between 500 and 2,000 Dalton and a Mw of between 800 and 4,000 Dalton. The crosslinkable composition comprises the polyol component (A) and a crosslinker (C) comprising functional groups reactable with polyacrylate polyol (A1). The crosslinkable composition is especially suitable for clear coat and top coat applications.

Abstract: The technology is directed to a system that allocates a frequency band to a satellite within a non-terrestrial network (NTN) and determines the available channel bandwidth for data transmissions within that frequency band. If the satellite detects an absence of a Radio Resource Control (RRC) connection between the satellite and at least one terminal device within the geographical location, which indicates a lack of active communication with the terminal devices, the satellite responds by transmitting signals at a reduced transmit power and within a portion of the available channel bandwidth towards the geographical location. The RRC connection can be managed by an RRC protocol.

Abstract: An anti-breakage self-locking universal surgical clamp is provided, which includes a handle body, a hook, a first nickel titanium wire rope, a front handle, and a clamp head. An inner wall side of the handle body is fixedly provided with a first positioning screw, and an outer wall side of the handle body is movably provided with the front handle. An outer wall side of the handle body is movably provided with the clamp head, the inner wall side of the handle body is fixedly provided with the hook. An outer wall side of the first positioning screw is fixedly provided with a first tension spring, which is connected to the hook through a head tension hook. The present disclosure achieves opening and closing function of surgical clamp by the front handle, the first nickel titanium wire rope, and a return spring.

Abstract: A method performed by a user equipment (UE) in a wireless communication system, the method including receiving, from a base station (BS), system information associated with a cell; and performing an authentication procedure with the BS, wherein the performing the authentication procedure includes receiving, from the BS, a challenge message comprising first shared secret information; transmitting, to the BS, a challenge response message comprising second shared secret information; and receiving, from the BS, an approval message; and initiating a cell camping procedure based on the approval message.