Abstract: Disclosed is a compound having a structure in formula I. The compound of the present invention has good enzyme inhibitory activity against EGFR mutants (L858R/T790M/C797S, del19/T790M/C797S, del19/C797S, L858R/C797S), a weak inhibitory effect on wild-type EGFR, and good selectivity. The compound has significant inhibitory activity against the proliferation of EGFR mutant cells, and has potential application value in the treatment of diseases related to cell proliferation. The compound of the present invention has good solubility and permeability, good in-vivo metabolic stability, high in-vivo exposure, and high bioavailability, and is a potential pharmaceutical compound.

Abstract: A signal acquisition method and device. Positioning signals as received are divided into at least two groups and frequency compensation is performed on each group of positioning signals. Each frequency compensated group of positioning signals is divided into at least two signal blocks, and an averaging operation is performed on the signal blocks in each group of signals, so as to obtain block-averaged groups of positioning signals. An acquisition result is determined based on the block-averaged groups of positioning signals. Noise power of each block-averaged group of signals is reduced. Therefore, noise power of received positioning signals can be reduced. This may improve signal-to-noise ratio of received signals and acquisition sensitivity of a receiver. Therefore, acquisition success rate of weak signals is increased.

Abstract: A signal acquisition method and device. Positioning signals as received are divided into at least two groups and frequency compensation is performed on each group of positioning signals. Each frequency compensated group of positioning signals is divided into at least two signal blocks, and an averaging operation is performed on the signal blocks in each group of signals, so as to obtain block-averaged groups of positioning signals. An acquisition result is determined based on the block-averaged groups of positioning signals. Noise power of each block-averaged group of signals is reduced. Therefore, noise power of received positioning signals can be reduced. This may improve signal-to-noise ratio of received signals and acquisition sensitivity of a receiver. Therefore, acquisition success rate of weak signals is increased.

Abstract: A signal acquisition method and device. Positioning signals as received are divided into at least two groups and frequency compensation is performed on each group of positioning signals. Each frequency compensated group of positioning signals is divided into at least two signal blocks, and an averaging operation is performed on the signal blocks in each group of signals, so as to obtain block-averaged groups of positioning signals. An acquisition result is determined based on the block-averaged groups of positioning signals. Noise power of each block-averaged group of signals is reduced. Therefore, noise power of received positioning signals can be reduced. This may improve signal-to-noise ratio of received signals and acquisition sensitivity of a receiver. Therefore, acquisition success rate of weak signals is increased.

Abstract: Embodiments of the present disclosure propose analog-to-digital conversion (ADC) systems particularly suitable for Light Detection and Ranging (LIDAR) implementations. An exemplary proposed ADC system is configured to determine whether an absolute value of an analog value is greater than a threshold, and, upon positive determination, assign a predetermined digital value as a digital value corresponding to the analog value, without proceeding with the analog-to-digital conversion of the analog value. Because the ADC system only proceeds with the analog-to-digital conversion, using an ADC, when the input analog value is smaller than the threshold, and otherwise the input analog value is simply assigned some predefined digital value, design complexity and power consumption of the system may be significantly reduced, compared to conventional ADCs used in LIDAR applications.

Abstract: Provided is a display substrate and a manufacturing method thereof a display panel and a display device. The display substrate comprises: a base substrate, and black matrixes, color filters and a blocking layer provided above the base substrate, the blocking layer being provided above the black matrixes and the color filters and being configured to block diffusion of particles generated by the color filters and/or the black matrixes. In the solutions of the display substrate and a manufacturing method thereof and a display device provided in the present application, the blocking layer is provided above the black matrixes and the color filters, and can block the particles generated by the color filters and/or the black matrixes, preventing the generated particles from diffusing to the opposite substrate facing the display substrate, generation of the progressive Zara can be prevented.

Abstract: A motherboard, a motherboard of a display panel, a liquid crystal display panel and a display device are provided. The motherboard includes: a base substrate (101, 201), and a plurality of substrate units (102, 202) arranged in a matrix on the base substrate (101, 201); and a line layer (103, 203) insulated from the substrate units (102, 202) and arranged along a preset extending direction (AA?, BB?), which is disposed within a peripheral region of the substrate units (102, 202). Because the line layer arranged along the preset extending direction is disposed within the peripheral space region of the substrate unit, when the alignment film on the substrate unit is aligned by a rubbing process, it can play a role in carding the rubbing cloth used in the rubbing process, to achieve an even rubbing effect, avoid an uneven rubbing phenomenon, and further facilitate improving a picture quality of the display panel.

Abstract: The disclosure relates to a hybrid aqueous rechargeable battery, wherein the battery comprises a positive electrode and a negative electrode, and wherein the positive electrode and the negative electrode are in aqueous electrolytes with different pHs respectively. The hybrid aqueous rechargeable battery has a working voltage at least 0.6 V higher than the conventional aqueous lithium batteries and a theoretical energy density at least 60 Wh/kg higher. The hybrid aqueous rechargeable battery can be used for storage and discharge of electricity, etc.

Abstract: The present application provides a display substrate and a display device. The display substrate includes a display region and a non-display region, a surface layer of the display region being rubbed to form an alignment layer, the non-display region being provided with a test electrode, the test electrode including multiple strip-shaped first sub-electrodes, the extending direction of the first sub-electrodes being the same with the direction of the rubbing for forming the alignment layer. By dividing the test electrode into multiple strip-shaped first sub-electrodes and the extending direction of the first sub-electrodes (i.e., the length direction) being the same as the rubbing direction of the rubbing to form an alignment layer, the display substrate can make the alignment of the alignment layer formed by the rubbing consistent and uniform, thereby avoiding the occurrence of Rubbing Mura when the alignment layer is formed by the rubbing.

Abstract: Embodiments of the present disclosure propose analog-to-digital conversion (ADC) systems particularly suitable for Light Detection and Ranging (LIDAR) implementations. An exemplary proposed ADC system is configured to determine whether an absolute value of an analog value is greater than a threshold, and, upon positive determination, assign a predetermined digital value as a digital value corresponding to the analog value, without proceeding with the analog-to-digital conversion of the analog value. Because the ADC system only proceeds with the analog-to-digital conversion, using an ADC, when the input analog value is smaller than the threshold, and otherwise the input analog value is simply assigned some predefined digital value, design complexity and power consumption of the system may be significantly reduced, compared to conventional ADCs used in LIDAR applications.

Abstract: An array substrate, a method of manufacturing the array substrate, and a display device are disclosed, for eliminating white Mura defects generated during the Cell process. The method comprises steps of: forming a display area and a non-display area on a substrate, a circuit bonding area being arranged within the non-display area; forming an alignment film within the display area through a patterning process; forming, through a patterning process, a transparent protection layer at least in a portion of the non-display area other than the circuit bonding area; and forming, through a rubbing-imprinting process, a plurality of lines having the same orientation on a surface of the alignment film, for an ordered arrangement of liquid crystal molecules, wherein a surface height of the transparent protection layer is lower than or equal to a surface height of the alignment film.

Abstract: Embodiments of the present invention provide an array substrate and a display device. The array substrate comprises a display area and a non-display area located in the periphery of the display area. A signal unit for transmitting external control signal and a gap region in which the signal unit is not disposed are provided in the non-display area. An auxiliary unit is disposed in the gap region, and the auxiliary unit and the signal unit have the same height and are electrically isolated from each other. A surface pattern of the signal unit is the same as that of the auxiliary unit in any corresponding part. In the array substrate, the segment difference in the non-display area due to the wiring are eliminated, and Rubbing Mura due to uneven rubbing strength of the rubbing roller on the periphery is reduced or eliminated, thereby achieving consistent rubbing effects.

Abstract: A display panel and a display device are provided. The display panel includes: a color filter substrate and an array substrate which are cell-assembled together, spacers disposed between the color filter substrate and the array substrate, the spacers include a plurality of primary spacers; a distribution density of the primary spacers in the display edge area is larger than a distribution density of the primary spacers in the display central area and larger than a density of the primary spacers in the display middle area.

Abstract: The disclosure discloses a display substrate and a manufacturing method thereof a display panel and a display device. The display substrate comprises: a base substrate, and black matrixes, color filters and a blocking layer provided above the base substrate, the blocking layer being provided above the black matrixes and the color filters and being configured to block diffusion of particles generated by the color filters and/or the black matrixes. In the solutions of the display substrate and a manufacturing method thereof and a display device provided in the present disclosure, the blocking layer is provided above the black matrixes and the color filters, and can block the particles generated by the color filters and/or the black matrixes, preventing the generated particles from diffusing to the opposite substrate facing the display substrate, generation of the progressive Zara can be prevented.

Abstract: The present application provides a display substrate and a display device. The display substrate includes a display region and a non-display region, a surface layer of the display region being rubbed to form an alignment layer, the non-display region being provided with a test electrode, the test electrode including multiple strip-shaped first sub-electrodes, the extending direction of the first sub-electrodes being the same with the direction of the rubbing for forming the alignment layer. By dividing the test electrode into multiple strip-shaped first sub-electrodes and the extending direction of the first sub-electrodes (i.e., the length direction) being the same as the rubbing direction of the rubbing to form an alignment layer, the display substrate can make the alignment of the alignment layer formed by the rubbing consistent and uniform, thereby avoiding the occurrence of Rubbing Mura when the alignment layer is formed by the rubbing.

Abstract: Embodiments of the present invention provide an array substrate and a display device. The array substrate comprises a display area and a non-display area located in the periphery of the display area. A signal unit for transmitting external control signal and a gap region in which the signal unit is not disposed are provided in the non-display area. An auxiliary unit is disposed in the gap region, and the auxiliary unit and the signal unit have the same height and are electrically isolated from each other. A surface pattern of the signal unit is the same as that of the auxiliary unit in any corresponding part. In the array substrate, the segment difference in the non-display area due to the wiring are eliminated, and Rubbing Mura due to uneven rubbing strength of the rubbing roller on the periphery is reduced or eliminated, thereby achieving consistent rubbing effects.

Abstract: A motherboard, a motherboard of a display panel, a liquid crystal display panel and a display device are provided. The motherboard includes: a base substrate (101, 201), and a plurality of substrate units (102, 202) arranged in a matrix on the base substrate (101, 201); and a line layer (103, 203) insulated from the substrate units (102, 202) and arranged along a preset extending direction (AA?, BB?), which is disposed within a peripheral region of the substrate units (102, 202). Because the line layer arranged along the preset extending direction is disposed within the peripheral space region of the substrate unit, when the alignment film on the substrate unit is aligned by a rubbing process, it can play a role in carding the rubbing cloth used in the rubbing process, to achieve an even rubbing effect, avoid an uneven rubbing phenomenon, and further facilitate improving a picture quality of the display panel.

Abstract: An array substrate, a method of manufacturing the array substrate, and a display device are disclosed, for eliminating white Mura defects generated during the Cell process. The method comprises steps of: forming a display area and a non-display area on a substrate, a circuit bonding area being arranged within the non-display area; forming an alignment film within the display area through a patterning process; forming, through a patterning process, a transparent protection layer at least in a portion of the non-display area other than the circuit bonding area; and forming, through a rubbing-imprinting process, a plurality of lines having the same orientation on a surface of the alignment film, for an ordered arrangement of liquid crystal molecules, wherein a surface height of the transparent protection layer is lower than or equal to a surface height of the alignment film.

Abstract: The present invention provides systems and methods for implementing narrowly spaced correlators to mitigate multipath error, and systems and methods for adaptively changing the correlator spacing for varying multipath conditions. In an embodiment, two sets of correlators with the same code frequency but different code phases are used to implement an adjustable correlator spacing. The correlator spacing is determined by the code phase difference between the two sets of correlators, which can be adjusted, e.g., by adjusting the code phase values of Numerically Controlled Oscillators (NCOs). An advantage of embodiments of the present invention is that they can achieve much narrower correlator spacings than conventional techniques, e.g., by making the code phase difference between the two sets of correlators very small. Further, the correlator spacing can be adjusted for varying multipath conditions, whereas the correlator spacing in conventional techniques is fixed.

Abstract: The present invention provides GPS receivers capable of tracking very weak GPS signals particularly in an indoor environment without assistance from an external server or a network. In a preferred embodiment, a GPS receiver initially acquires and locks onto GPS satellite signals to compute receiver position outdoors. The GPS receiver then tracks at least one satellite signal indoors to maintain acquisition parameters for quick acquisition of GPS signals. To save power, the receiver automatically goes to the sleep state and periodically wakes up, i.e., powers up, to maintain the at least one satellite signal tracking. During the wakeup state, the receiver collects ephemeris data from the at least one satellite signal when the ephemeris data needs to be updated for quick acquisition of GPS signals.