Abstract: The disclosure relates to a protein-type nanoparticle for multi-specific antibody delivery, a preparation method, and its application. The protein-type nanoparticle includes a polyester and a protein with a hydrophobic domain, and the hydrophobic domain of the protein is bound with the polyester through hydrophobic interactions. The protein is at least one of albumin, globulin and cell wall protein. The protein-type nanoparticle of the present disclosure has excellent stability and biocompatibility. The protein-type nanoparticle is used to prepare a multi-specific antibody delivery platform (?Fc-NP) by binding anti-IgG-Fc antibody or anti-IgG-Fc antibody fragment, which can stably, quickly and easily bind to multiple specific antibodies through antigen-antibody interaction and enhance the therapeutic effect of specific antibodies.

Abstract: Disclosed is a mobile phone clip, including: a clamping member, a supporting member, and a base. The clamping member is rotatably connected to the supporting member through a first rotating assembly, the supporting member is rotatably connected to the base through the second rotating assembly, and a third rotating assembly is provided on the base. The second rotating assembly is configured to rotate supporting member to adjust a pitch angle of the mobile phone, the base is provided with a third rotating assembly for connecting an external equipment, and the third rotating assembly is configured to horizontally rotate the base to change an orientation of the mobile phone.

Abstract: A method in a wireless device is provided. The method includes: receiving a downlink signal, wherein the downlink signal includes a Physical Downlink Control Channel (PDCCH) and a Physical downlink Shared Channel (PDSCH), the PDCCH having first downlink Control Information (DCI) indicating at least second downlink control information (DCI) in the PDSCH; and performing one of encoding and decoding user data in the PDSCH based on the first DCI and second DCI. A wireless device implementing this method is provided as well.

Abstract: Systems, methods, and computer storage media having computer-executable instructions embodied thereon that return query completions are provided. A user of a computing device like a mobile phone may enter a prefix. In turn, the prefix and location information associated with the device are transmitted to a server device. The server device receives the prefix and location information. The prefix and the location information are matched with names and locations of entities stored in a database connected to the server device. The server device transmits query completion data to the mobile device. The query completion data includes one or more names that complete the received prefix. The names provided by the server device may be associated with entities that are within a threshold radius of the location information.

Abstract: A pod deployment method is provided, to increase container deployment flexibility, and meet an access requirement of a user, including: A scheduler obtains requirement information and a pod annotation from an application management cluster. The requirement information includes a time period and a user quantity corresponding to the time period, and the pod annotation indicates a user quantity supported by a single pod. The scheduler determines, based on the user quantity corresponding to the time period and the user quantity supported by the single pod, a quantity M of pods that need to be deployed in the time period, and determines a target node used to deploy the M pods. The scheduler generates a deployment plan based on the quantity M of pods that need to be deployed in the time period and the target node used to deploy the M pods.

Abstract: A display substrate including a drive-circuit layer and a light-emitting structure layer, a preparation method thereof, and a display device, the light-emitting structure layer includes an anode, a pixel definition layer, an organic light-emitting layer and a cathode, and an auxiliary electrode and an organic light-emitting block, arranged sequentially, the pixel definition layer includes an anode opening exposing the anode and an electrode opening exposing the auxiliary electrode, the organic light-emitting block is separated from the organic light-emitting layer, the auxiliary electrode includes the first, second and third auxiliary electrodes arranged sequentially; the cathode includes a first horizontal lapping part lapping with the first auxiliary electrode and a second sidewall lapping part lapping with the second auxiliary electrode, the thickness of the second sidewall lapping part in the direction parallel to the substrate is greater than that of the first horizontal lapping part in the direction per

Abstract: Provided herein are compounds useful in the treatment of inflammatory diseases, pharmaceutical compositions comprising the same, and methods of use and preparation thereof. The compounds exhibit inhibitory effects on the expression and secretion of pro-inflammatory cytokines, such as IL-1?, IL-6 and TNF-?.

Abstract: The present disclosure relates to the field of materials for uranium extraction from seawater (UES), and in particular, to a photothermal photocatalytic membrane for seawater desalination and uranium extraction and a preparation method therefor. The present disclosure provides a photothermal photocatalytic membrane for seawater desalination and uranium extraction and a preparation method therefor. The preparation method includes: fixing a treated carbon cloth to a glass plate, pouring a casting solution 1 onto the carbon cloth to form a first layer of film, forming a second layer of film using a casting solution 2, and putting the second layer of film into a first coagulation bath and a second coagulation bath in sequence to form the photothermal photocatalytic membrane. The photothermal photocatalytic membrane is supported by the carbon cloth, and a surface of the photothermal photocatalytic membrane is of a micro-nano structure.

Abstract: The present application discloses a method, a device, equipment, and storage medium for determining a sensor solution, where the method includes: establishing a simulated unmanned vehicle and a simulation scene, where the simulation scene is used for the simulated unmanned vehicle to perform simulation driving; determining a first sensor solution according to a initialization parameter, and determining, according to the first sensor solution, simulation data generated by the simulated unmanned vehicle during the simulation driving in the simulation scene; and; and determining a first perception parameter of the first sensor solution according to the simulation data, and correcting the first sensor solution according to the first perception parameter to obtain a sensor solution applied to an unmanned vehicle.

Abstract: Determining an active jacking force of a tunneling closely undercrossing existing station, includes: acquiring design parameters of stations, and geological parameters of a construction site; obtaining a stress solution expression of the active jacking force on the existing station to obtain a stress solution of any point in a semi-infinite space under the action of a vertical load, replacing the vertical load with a vertical load acting on the existing station, and obtain a vertical stress solution of the existing station; obtaining a relational expression between the deflection and the stress solution of the existing station; and substituting the stress solution expression of the active jacking force into the relational expression between the deflection and the stress solution of the existing station according to boundary conditions at both ends of a beam on elastic foundation to obtain the active jacking force that controls the deflection of the existing station.

Abstract: A decision-making method for variable rate irrigation management includes the following steps: S1: sampling a soil from a root zone of a crop in an area controlled by an irrigation sprinkler, and measuring compositions of separates of the sampled soil; S2: managing and dividing the area controlled by the irrigation sprinkler according to an AWC of the soil in the root zone of the crop; S3: constructing an optimized soil moisture sensor network; S4: placing ground-fixed canopy temperature sensors; S5: constructing an optimized airborne canopy temperature sensor network centered on the center pivot; and S6: performing a variable rate irrigation by using the optimized soil moisture sensor network, the fixed canopy temperature sensors, the optimized airborne canopy temperature sensor network and an automatic weather station. The method optimizes the placement and quantity of the soil moisture sensor network and the canopy temperature sensor network to improve the measurement accuracy.

Abstract: A multi-axis turntable includes a base, a rocker arm and a first driving device capable of driving the rocker arm to rock around the first rotation axis on the base. A swing arm and a second driving device, which is capable of driving the swing arm to swing around the second rotation axis on the rocker arm, are provided on the rocker arm. A workbench and a third driving device for driving the workbench to rotate around the third rotation axis are provided on the swing arm. The second rotation axis and the third rotation axis are parallel to each other or on different planes. Compared with the existing double rotating shaft turntable, the multi-axis turntable of the present invention has a cutting tool system of good and stable rigidity.

Abstract: Embodiments of the present disclosure relate to a method, system and computer program product for semantic search based on a graph database. In some embodiments, a method is disclosed. According to the method, the user jobs of a user are obtained from a first software product. Based on the user jobs, target test cases are selected from a plurality of test cases associated with the first software product and a second software product. The target test cases are applied to the first software product and the second software product, and in accordance with a determination that a result of applying the target test cases satisfies a predetermined criterion, an instruction is provided to indicate migrating from the first software product to the second software product. In other embodiments, a system and a computer program product are disclosed.

Abstract: A malware profile is received. The malware profile comprises a set of n-tuples of attributes that describe one or more activities associated with executing a copy of a known malicious application that is associated with the malware profile. A set of one or more log entries is analyzed for a set of entries that matches the malware profile. Based at least in part on identifying the set of entries matching the malware profile, a determination is made that a host was compromised. In response to determining that the host has been compromised, a remedial action is taken with respect to the host.

Abstract: Corresponding template features and search features are obtained by convolution operation, and respectively used as input features in aggregation modules. Intermediate features are obtained by performing convolution operation on the input features. The aggregation modules share the same convolution operation, and hybrid convolution in the aggregation module uses a depthwise convolution and a pointwise convolution to separate mixture between space and channel of the intermediate features. Redundancy in spatial and channel features is reduced while increasing receptive field. Self-attention module in the aggregation module learns intermediate features, and adaptively focuses on different regions to capture more global correlations. Output features of the hybrid convolution are added to output features of the self-attention module to pass through a drop-out layer to obtain final output features. The output features aggregate local and global context information.

Abstract: The invention discloses a monoclonal antibody against human GPR48 and application of the same. In the antibody provided by the present invention, the amino acid sequences of LCDR1, LCDR2, and LCDR3 in the light chain variable region are shown in positions 27-32, 50-52, and 89-97 of SEQ ID No.1 sequentially, and the amino acid sequences of HCDR1, HCDR2 and HCDR3 in the heavy chain variable region are shown in positions 26-33, 51-60 and 99-108 of SEQ ID No.2 sequentially. The antibody has strong specificity and sensitivity to GPR48 protein, and can be applied to immunological experimental techniques such as western blotting, immunofluorescence and immunohistochemistry; it can be applied to flow cytometry experimental techniques such as flow cyometry analysis and flow cytometry sorting; it can be applied to the scientific research of signaling pathways such as subcellular localization and protein interaction.