Abstract: A pump unit includes a pump and a metal ion trap. The pump includes a metal member that comes into contact with a mobile phase. The pump pumps a mobile phase through a flow path. The metal ion trap includes a filter element. The filter element includes a metal ion retention structure for retaining metal ions by interacting with the metal ions included in a mobile phase. The filter element is provided in the flow path for a mobile phase pumped by the pump. The pump unit may be provided in a chromatograph.

Abstract: A resin tube is prepared. Further, a formation tool having a pressing surface and a projection that projects from the pressing surface and is insertable into the resin tube is prepared. The projection of the formation tool is inserted from an end of the resin tube into the resin tube. The pressing surface of the formation tool is pressed against an end surface of the resin tube. Thermal energy is applied to the end of the resin tube, whereby a shape of the pressing surface of the formation tool is transferred to the end surface of the resin tube, and the end of the resin tube is formed into a flange shape.

Abstract: A fitting includes a screw portion that is rotatable around an axis extending in one direction, an operating portion that applies a torque around the axis to the screw portion, and a rotation auxiliary member that is configured to be engageable with the operating portion. A slot extending from a first end to a second end is provided in the rotation auxiliary member, and also a first projection that protrudes outward is provided on the rotation auxiliary member. A positional relationship of the first projection is set such that an engaging force between the rotation auxiliary member and the operating portion is increased due to a change in width of the slot in a case where a force is applied to the first projection in the first rotation direction with the rotation auxiliary member engaging with the operating portion.

Abstract: A binary pump in which an operation controller causes each of two liquid delivery pumps to execute, while a secondary discharge process is executed, a suction process, a first pre-pressurizing process, and a standby process. The operation controller causes each of the two liquid delivery pumps to execute a second pre-pressurizing process before proceeding from the secondary discharge process to the primary discharge process. Furthermore, the operation controller causes, as long as continuous liquid delivery by each of the two liquid delivery pumps is not interrupted, at least one of the two liquid delivery pumps to execute avoidance operation of interrupting the standby process and proceeding to the second pre-pressurizing process by using the operation state of each of the two liquid delivery pumps, so as to avoid overlap of execution time zones of the primary discharge processes of the two liquid delivery pumps.

Abstract: A liquid delivery pump includes a primary plunger pump, a secondary plunger pump fluidly connected in series downstream of the primary plunger pump, and a pressure sensor that detects a system pressure. The liquid delivery pump further includes a liquid delivery control part configured to execute first constant pressure control in a first constant pressure control term and to execute second constant pressure control in a second constant pressure control term. The first constant pressure control term is a term, which is in a liquid delivery cycle consisting of the primary discharge process and the secondary discharge process, in which the primary discharge process is executed, the second constant pressure control term is a part of a term in which the secondary discharge process is executed, and the second constant pressure control term is including a term that is continuous after the first constant pressure control term.

Abstract: A bioinert piping (1) that has a flow path (2) provided inside and a main body portion (10) between end portions (8, 8) includes a resin tube (4) that forms an inner wall of the flow path (2) over an entire length of the flow path (2), and a metal tube (6) that accommodates the resin tube (4) inside so as to cover the outer peripheral surface of the resin tube (4) over at least an entire length of the main body portion (10). The metal tube (6) is plastically deformed toward an inner side so that the outer peripheral surface of the resin tube (4) and an inner peripheral surface of the metal tube (6) are in liquid-tight contact with each other.

Abstract: A field-flow fractionation device includes a separation channel, a carrier fluid supplier, a separation membrane, a waste liquid chamber, a cross-flow flow rate adjuster, and a carrier fluid adder. The carrier fluid adder is configured to add, to a flow of a carrier fluid having passed through the separation membrane, a flow of another carrier fluid at a carrier fluid adding position set on an upstream side of the cross-flow flow rate adjuster so that the flow rate of the carrier fluid flowing into the cross-flow flow rate adjuster is larger than the flow rate of the carrier fluid having passed through the separation membrane.

Abstract: A resin tube connection device includes a resin tube, a resin expanding portion and a metal sleeve. The resin expanding portion has a sealing surface being able to come into contact with a contact surface. Further, the resin expanding portion has a second flow path that communicates with a first flow path of the resin tube and opens in the sealing surface. The sealing surface projects farther than an end surface of the metal sleeve in an axial direction. The maximum length of a contact region where the resin expanding portion and the metal sleeve come into contact with each other in the axial direction in an outer surface is larger than the thickness of a resin layer in a radial direction.

Abstract: A ratchet fitting includes a screw portion and an operating portion. One of the screw portion and the operating portion has an engaging member, and the other one of the screw portion and the operating portion has an elastic member and a holding member formed separately from the elastic member. The elastic member and the engaging member are fitted such that a rotational force is transmittable to each other due to engagement of the projection and the protrusion and engagement between the projection and the protrusion is releasable due to deformation of the elastic member. The elastic member has a first fitting portion, the holding member has a second fitting portion, and the holding member and the elastic member are fitted such that the first fitting portion and the second fitting portion are fitted to each other in a rotation direction.

Abstract: A pump unit includes a pump and a metal ion trap. The pump includes a metal member that comes into contact with a mobile phase. The pump pumps a mobile phase through a flow path. The metal ion trap includes a filter element. The filter element includes a metal ion retention structure for retaining metal ions by interacting with the metal ions included in a mobile phase. The filter element is provided in the flow path for a mobile phase pumped by the pump. The pump unit may be provided in a chromatograph.

Abstract: An autosampler sets an injection valve to be in a sample filling state when a sample loop is filled with a sample, and, after completion of filling with the sample, switches the injection valve to an intermediate state and first connects only one end of the sample loop to a liquid delivery channel and an analysis channel. After the above, the injection valve is switched to the sample injection state and the sample loop is interposed between the liquid delivery channel and the analysis channel, so that the sample is injected into the analysis channel.

Abstract: A ratchet fitting includes a screw portion and an operating portion. One of the screw portion and the operating portion has an engaging member, and the other one of the screw portion and the operating portion has an elastic member and a holding member formed separately from the elastic member. The elastic member and the engaging member are fitted such that a rotational force is transmittable to each other due to engagement of the projection and the protrusion and engagement between the projection and the protrusion is releasable due to deformation of the elastic member. The elastic member has a first fitting portion, the holding member has a second fitting portion, and the holding member and the elastic member are fitted such that the first fitting portion and the second fitting portion are fitted to each other in a rotation direction.

Abstract: A fitting includes a screw portion that is rotatable around an axis extending in one direction, an operating portion that applies a torque around the axis to the screw portion, and a rotation auxiliary member that is configured to be engageable with the operating portion. A slot extending from a first end to a second end is provided in the rotation auxiliary member, and also a first projection that protrudes outward is provided on the rotation auxiliary member. A positional relationship of the first projection is set such that an engaging force between the rotation auxiliary member and the operating portion is increased due to a change in width of the slot in a case where a force is applied to the first projection in the first rotation direction with the rotation auxiliary member engaging with the operating portion.

Abstract: A bioinert pipe includes a flow path inside, an inner wall of the flow path is composed of a resin tube and an outer peripheral surface of the resin tube is covered with a metal tube. The bioinert pipe includes an end portion extension member attached to an end portion of the metal tube, and the end portion extension member is made from a material harder than the resin tube and has a first surface and a second surface. The first surface is facing and in contact with an end surface of the metal tube and the second surface is directed opposite to the first surface. a through hole having an inner diameter substantially the same as an inner diameter of the metal tube is provided so as to pass from the first surface to the second surface in the end portion extension member. An edge of the through hole on the second surface of the end portion extension member has a chamfered shape, and the resin tube is inserted into the through hole.

Abstract: A bioinert piping (1) that has a flow path (2) provided inside and a main body portion (10) between end portions (8, 8) includes a resin tube (4) that forms an inner wall of the flow path (2) over an entire length of the flow path (2), and a metal tube (6) that accommodates the resin tube (4) inside so as to cover the outer peripheral surface of the resin tube (4) over at least an entire length of the main body portion (10). The metal tube (6) is plastically deformed toward an inner side so that the outer peripheral surface of the resin tube (4) and an inner peripheral surface of the metal tube (6) are in liquid-tight contact with each other.

Abstract: A liquid feeding device includes a discharge channel, a pump part, a feeding pressure sensor, a non-discharge pressure sensor, a pre-compression part, and a pre-compression speed determination part. The pump part has plunger pumps connected in series or parallel. At least one of the plunger pumps is a closed pump in which communication with the discharge channel is disconnected during a non-discharge time. The pre-compression part causes the closed pump that is after the suction process for sucking the liquid into a pump chamber is completed and during the non-discharge time to execute a pre-compression process to perform a discharge operation until a non-discharge pressure is substantially the same as a feeding pressure based on output of the feeding pressure sensor and output of the non-discharge pressure sensor. The pre-compression speed determination part determines a pre-compression speed of the closed pump in the pre-compression process.

Abstract: A liquid delivery device includes at least one liquid delivery pump that delivers liquid, at least one main channel communicating with an outlet of the liquid delivery pump, at least one branch channel branched from the main channel, and a switching valve that has, as a port for connecting channels, at least a port to which the main channel is connected, a port to which the branch channel is connected, at least one output port for outputting liquid delivered by the liquid delivery pump through the main channel, and at least one drain port leading to a drain, and is configured to be selectively switched to a first state, in which the main channel is connected to the output port while the branch channel is not connected to any channel, and a second state in which the branch channel is connected to the drain port while the main channel is not connected to any channel.

Abstract: A binary pump in which an operation controller causes each of two liquid delivery pumps to execute, while a secondary discharge process is executed, a suction process, a first pre-pressurizing process, and a standby process. The operation controller causes each of the two liquid delivery pumps to execute a second pre-pressurizing process before proceeding from the secondary discharge process to the primary discharge process. Furthermore, the operation controller causes, as long as continuous liquid delivery by each of the two liquid delivery pumps is not interrupted, at least one of the two liquid delivery pumps to execute avoidance operation of interrupting the standby process and proceeding to the second pre-pressurizing process by using the operation state of each of the two liquid delivery pumps, so as to avoid overlap of execution time zones of the primary discharge processes of the two liquid delivery pumps.

Abstract: A liquid delivery pump includes a primary plunger pump, a secondary plunger pump fluidly connected in series downstream of the primary plunger pump, and a pressure sensor that detects a system pressure. The liquid delivery pump further includes a liquid delivery control part configured to execute first constant pressure control in a first constant pressure control term and to execute second constant pressure control in a second constant pressure control term. The first constant pressure control term is a term, which is in a liquid delivery cycle consisting of the primary discharge process and the secondary discharge process, in which the primary discharge process is executed, the second constant pressure control term is a part of a term in which the secondary discharge process is executed, and the second constant pressure control term is including a term that is continuous after the first constant pressure control term.

Abstract: Even though a pump head part is finally fixed to a pump body with a fixing member, the pump head part is movable relative to the pump body perpendicular to the axial direction of a plunger at a stage before the pump head part is fixed with the fixing member. In this state, if a plunger driving part is moved to a predetermined location on the front end side of the pump body and the pump head part and the plunger driving part are fitted to each other, the pump head part is positioned where the center axis of the plunger and the center axis of the pump chamber are substantially aligned. By fixing the pump head part to the pump body with the fixing member at this location, it is possible to assemble a plunger pump with the center axis of the plunger and the center axis substantially aligned.