Abstract: Examples of methods for generating supports are described herein. In some examples, a method includes determining a starting position from a set of voxels of a three-dimensional (3D) object model to be additively manufactured. In some examples, the method also includes generating a support for the 3D object model by traversing a cost field from the starting position.

Abstract: Examples of methods are described. In some examples, a method includes generating, using a first branch of a machine learning model, a first agent map based on a layer image. In some examples, the method includes generating, using a second branch of the machine learning model, a second agent map. In some examples, the first agent map and the second agent map indicate printing locations for different agents.

Abstract: The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.

Abstract: According to examples, a processor may identify locations on a digital 3D model of an object corresponding to positions at which features are to be added to the object. For each of a plurality of locations of the identified locations, the processor may identify displacements of each of a plurality of patch points around the location from the surface of the digital 3D model. The processor may also create a map of the digital 3D model that encodes the identified displacements of the patch points around the locations, in which a 3D fabrication system is to fabricate the object to include the plurality of features based on the digital 3D model and the created map.

Abstract: Examples disclosed herein relate to 3D printer fresh and recycled powder supply management. In one implementation, a processor estimates fresh and recycled powder use and recycled powder creation by a 3D printer based on a set of print jobs. The processor may coordinate fresh and recycled powder resources based on the powder estimate and stored information about powder resources.

Abstract: Described herein are compounds that are inhibitors of p21-activated kinases (PAKS). In particular, the compounds described herein are demonstrated to be selective PAK4 inhibitors. The compounds described herein are also demonstrated to reduce the expression of key immune checkpoint molecules, such as PD-1 and CHEK2. Also described herein are pharmaceutical compositions containing such compounds, methods for using such compounds in the treatment of cancers, more specifically, the treatment of pancreatic and lung cancers, and to related uses.

Abstract: The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.

Abstract: A cell alignment metric detection method, a controller, a detection system and a storage medium are disclosed. The cell alignment metric detection method includes: acquiring a first cell image; inputting the first cell image into a first training model for detection processing to obtain a region of interest; obtaining a second cell image and terminal position information of a second electrode plate according to the region of interest and the first cell image; inputting the second cell image into a second training model for separation processing to obtain a third cell image and terminal position information of a first electrode plate; performing image extraction and analysis on the third cell image to obtain a misalignment quantity; and obtaining the cell alignment metric according to the terminal position information of the second electrode plate and the first electrode plate and the misalignment quantity.

Abstract: Examples of methods for determining displacement maps are described herein. In some examples of the methods, a method includes determining a displacement map for a three-dimensional (3D) object model based on a compensated point cloud. In some examples, the method includes assembling the displacement map on the 3D object model for 3D manufacturing.

Abstract: The present disclosure generally relates to epidermal growth factor receptor (EGFR) inhibitors and methods of treating EGFR-dependent or associated diseases, disorders or conditions, such as cancer.

Abstract: Examples of methods for point cloud alignment are described herein. In some examples, a method includes orienting a model point cloud or a scanned point cloud based on a set of initial orientations. In some examples, the method includes determining, using a first portion of a machine learning model, first features of the model point cloud and second features of the scanned point cloud. In some examples, the method includes determining, using a second portion of the machine learning model, correspondence scores between the first features and the second features based on the set of initial orientations. In some examples, the method includes globally aligning the model point cloud and the scanned point cloud based on the correspondence scores.

Abstract: An explosion-proof luminaire with a color-temperature-adjustment function, including a housing, a dual-color-temperature LED panel, and a control circuit including an LED driver and a color-temperature control unit. The LED panel includes a first LED array and a second LED array varying in color temperature, which are controlled by the control circuit. Input and output ends of the LED panel are respectively connected to an output end of the LED driver and an input end of the control unit. The control unit includes a color-temperature DIP adjustment subunit, a color-temperature safe barrier control subunit, a voltage sampling subunit, a power supply control subunit, a central control subunit, a shunt control subunit and an interface subunit. The shunt control subunit is controlled by the central control subunit based on sampled voltage of the voltage sampling subunit, controlling circuit switching (on/off) of the first and second LED arrays.