Abstract: Provided is a method of forming a micro/nanowire having a nanometer- to micrometer-sized diameter at predetermined positions of an object. The method includes: preparing a micro/nanopipette having a tip with an inner diameter which is substantially the same as the diameter of the micro/nanowire to be formed; filling the micro/nanopipette with a solution containing a micro/nanowire-forming material; brining the solution into contact with the object through the tip of the micro/nanopipette; and pulling the micro/nanopipette from the object at a pulling speed lower than or equal to a predetermined critical speed (?c) to obtain a micro/nanowire having substantially the same diameter as the inner diameter of the micro/nanopipette tip.

Abstract: Provided is a method of fabricating a core-shell structured nanowire on a tip of an optical fiber, on a substrate, or any position on other target objects, and a nanowire fabricated by the method. The nanowire fabricated by the method of the present invention may be used for a drug delivery system, a sensor, an optical waveguide, and the like.

Abstract: Provided is a method of forming a micro/nanowire having a nanometer- to micrometer-sized diameter at predetermined positions of an object. The method includes: preparing a micro/nanopipette having a tip with an inner diameter which is substantially the same as the diameter of the micro/nanowire to be formed; filling the micro/nanopipette with a solution containing a micro/nanowire-forming material; brining the solution into contact with the object through the tip of the micro/nanopipette; and pulling the micro/nanopipette from the object at a pulling speed lower than or equal to a predetermined critical speed (?c) to obtain a micro/nanowire having substantially the same diameter as the inner diameter of the micro/nanopipette tip.

Abstract: Provided is a method of fabricating a micro/nanowire having a nanometer- to micrometer-sized diameter at predetermined positions on an object. The method comprises: preparing a micro/nanopipette having a tip with an inner diameter (dpt) which is substantially the same as the diameter of the micro/nanowire to be fabricated; filling the micro/nanopipette with a solution containing a micro/nanowire-forming material; bringing the solution into contact with the object through the tip of the micro/nanopipette; and pulling the micro/nanopipette apart from the object at a pulling speed lower than or equal to a predetermined critical pulling speed (vc) to fabricate a micro/nanowire having substantially the same diameter as the inner diameter of the micro/nanopipette tip (dpt). The critical pulling speed (vc) is defined by a maximum limit of the pulling speed at which the micro/nanowire to be fabricated has the same diameter as the inner diameter of the micro/nanopipette tip (dpt).

Abstract: Provided is a method and apparatus for measuring pH in single cells, and a method of manufacturing a nanoprobe therefor. The apparatus for measuring pH in a single cell comprises: a nanoprobe formed by labeling a pH-responsive fluorescent material to a nanowire grown on a tapered tip of an optical fiber; a manipulator capable of regulating a three-dimensional movement of the nanoprobe to insert the nanoprobe into a single living cell; a light source for applying light to the optical fiber; an optical coupler for connecting the optical fiber with another optical fiber to transmit the light incident through the optical fiber to the nanoprobe and to transmit a fluorescence signal obtained from the nanoprobe through the another optical fiber; and a spectrometer for obtaining a pH value by receiving the fluorescence signal through the another optical fiber and analyzing spectral data from the fluorescence signal.

Abstract: The present invention relates to a method of fabricating a nanowire connected to an optical fiber, the method comprising the steps of: a) filling a micropipette with a material solution to form a nanowire; b) coaxially aligning the micropipette with the optical fiber at one end of the optical fiber such that a longitudinal axis of the optical fiber and a longitudinal axis of the micropipette are aligned in a line; c) forming a meniscus of the material solution to form the nanowire in the coaxially aligned state; and d) fabricating the nanowire by evaporating a solvent from the material solution to form the nanowire while lifting the micropipette in a state in which the meniscus is formed, in a direction away from the optical fiber. The method further comprises a step of a step of controlling a shape of the distal end of the nanowire by irradiating a laser to the nanowire fabricated.

Abstract: The present invention relates to an optical interconnection for interconnecting a first contact and a second contact, which need to be optically interconnected, the optical interconnection comprising: a nanorod formed on at least one of the first contact and the second contact; and a nanowire extending from the first contact or the nanorod formed on the first contact so as to transmit an optical signal toward the second contact or the nanorod formed on the second contact. The optical interconnection according to the present invention shows improved optical signal characteristics due to a reduction in coupling loss.

Abstract: The present invention relates to a method of fabricating a nanowire connected to an optical fiber, the method comprising the steps of: a) filling a micropipette with a material solution to form a nanowire; b) coaxially aligning the micropipette with the optical fiber at one end of the optical fiber such that a longitudinal axis of the optical fiber and a longitudinal axis of the micropipette are aligned in a line; c) forming a meniscus of the material solution to form the nanowire in the coaxially aligned state; and d) fabricating the nanowire by evaporating a solvent from the material solution to form the nanowire while lifting the micropipette in a state in which the meniscus is formed, in a direction away from the optical fiber. The method further comprises a step of a step of controlling a shape of the distal end of the nanowire by irradiating a laser to the nanowire fabricated.

Abstract: The present invention relates to an optical interconnection for interconnecting a first contact and a second contact, which need to be optically interconnected, the optical interconnection comprising: a nanorod formed on at least one of the first contact and the second contact; and a nanowire extending from the first contact or the nanorod formed on the first contact so as to transmit an optical signal toward the second contact or the nanorod formed on the second contact. The optical interconnection according to the present invention shows improved optical signal characteristics due to a reduction in coupling loss.

Abstract: Particles and manufacturing methods thereof are provided. The manufacturing method of the particle includes providing a precursor solution containing a precursor dissolved in a solution, and irradiating the precursor solution with a high energy and high flux radiation beam to convert the precursor to nano-particles. Particles with desired dispersion, shape, and size are manufactured without adding a stabilizer or surfactant to the precursor solution.

Abstract: Images of blood vessels of a body are obtained by injecting a refraction enhancement contrast agent into the blood vessels to increase a difference in refractive indices of the blood vessels and surrounding material. The blood vessels are irradiated with a penetrating radiation, and an image of the blood vessels is generated based on detected radiation. The image has visible edge enhancement features indicating boundaries of the blood vessels.

Abstract: The present invention relates to a method for manufacturing an X-ray/?-ray focusing optical system comprising the steps of: providing a capillary substrate; and sequentially accumulating a plurality of alternation layers, each consisting of an X-ray/?-ray opaque material and an X-ray/?-ray transparent material, on an inner surface of the capillary substrate in a Fresnel pattern by atomic layer deposition.

Abstract: The present invention relates to a method for manufacturing an X-ray/?-ray focusing optical system comprising the steps of: providing a capillary substrate; and sequentially accumulating a plurality of alternation layers, each consisting of an X-ray/?-ray opaque material and an X-ray/?-ray transparent material, on an inner surface of the capillary substrate in a Fresnel pattern by atomic layer deposition.

Abstract: Disclosed is a method for modifying wettability of a surface of an inorganic material, the method comprising the steps of: preparing an inorganic material with a surface; and charging the surface of the inorganic material with positive surface charges obtained from photoelectron-emission by an X-ray irradiation to the surface of the inorganic material.

Abstract: Disclosed herein is a method for fabricating a three-dimensional ultrafine conducting polymer wire having a high aspect ratio by local chemical polymerization using a micropipette.

Abstract: Images of blood vessels of a body are obtained by injecting a refraction enhancement contrast agent into the blood vessels to increase a difference in refractive indices of the blood vessels and surrounding material. The blood vessels are irradiated with a penetrating radiation, and an image of the blood vessels is generated based on detected radiation. The image has visible edge enhancement features indicating boundaries of the blood vessels.

Abstract: Images of blood vessels of a body are obtained by injecting a refraction enhancement contrast agent into the blood vessels to increase a difference in refractive indices of the blood vessels and surrounding material. The blood vessels are irradiated with a penetrating radiation, and an image of the blood vessels is generated based on detected radiation. The image has visible edge enhancement features indicating boundaries of the blood vessels.

Abstract: Provided is a method of bright-field imaging using x-rays in a sample to reveal lattice defects as well as structural inhomogeneities, the method comprising: (a) disposing a sample on a holder in the Laue transmission geometry and setting the sample to a single reflection in the Bragg diffraction; (b) projecting a beam of monochromatic x-rays on the sample; and (c) obtaining transmitted radiographic images and reversed diffracted images of the projected beam of monochromatic x-rays by the sample, respectively.

Abstract: Disclosed is a method for ablating hyaluronan-based hydrogels with X-rays, the method comprising the steps of: (a) preparing hyaluronan-based hydrogels; and (b) performing X-ray irradiation to the hyaluronan-based hydrogels to induce a degradation of the hyaluronan-based hydrogels by a gel-to-sol transition during the X-ray irradiation. Disclosed is also a method for fabricating three-dimensional microchannels of hyaluronan hydrogels with a finely tunable X-ray ablation technique.

Abstract: A method for treating and/or diagnosing a tumor is provided. The method includes administrating an effective amount of gold particles to a subject in need thereof, and observing the distribution of the gold particles in the subject, wherein the gold particles are coated with a polymer, and the gold particle has a size of about 6.1±1.9 nm.