Abstract: A lens module is provided. The lens module includes at least one refractive index distribution lens; and a lens barrel configured to accommodate the at least one refractive index distribution lens, wherein the at least one refractive index distribution lens is composed of a single layer, and includes a plastic material.

Abstract: A light modulation element that can vary between a bright transparent mode and a dark scattering mode is provided. The light modulation element has a first light modulation layer and a second light modulation layer comprising nematic liquid crystals and a dichroic dye in a scattering mode when a voltage is applied. The first light modulation layer and the second light modulation layer are disposed to overlap each other. The light modulation element has an improved contrast ratio and haze-variable characteristics, without precipitation of dichroic dyes and an increase in power consumption.

Abstract: A bispecific anti-GPNMB/anti-CD3 antibody specifically binds to CD3 (cluster of differentiation 3) and GPNMB (glycoprotein non-metastatic melanoma protein B) and uses thereof are disclosed. The bispecific antibody shows high affinity and specificity to CD3 and GPNMB and thus can induce death of cancer cells expressing GPNMB and inhibit proliferation thereof. Therefore, the bispecific antibody can be used as an effective therapeutic agent for cancers expressing GPNMB.

Abstract: A light modulation device is disclosed herein. In some embodiments, a light modulation device includes a first polymer film substrate, a second polymer film substrate, an active liquid crystal layer disposed between the first and second polymer film substrates, wherein the active liquid crystal layer is capable of switching between a first orientation state and a second orientation state when a voltage is applied, and a polarizer, wherein each of the first and second polymer film substrates have in-plane retardation of 4,000 nm or more for light having a wavelength of 550 nm, a ratio of an elongation (E1) in a first direction to an elongation (E2) in a second direction perpendicular to the first direction of 3 or more, and wherein an angle formed by the first directions of the first and second polymer film substrates is in a range of 0 degrees to 10 degrees.

Abstract: The present application relates to a light modulation device and a use thereof. The present application can provide a light modulation device having both excellent mechanical properties and optical properties by applying a polymer film that is also optically anisotropic and mechanically anisotropic to a substrate.

Abstract: The present invention relates to a compound which inhibits the binding of Yes associated protein (YAP) and transcriptional enhancer associate domain (TEAD), a prodrug of same, a hydrate of same, a solvate of same or a pharmaceutically acceptable salt of same, and a composition comprising same as an active ingredient, the compound according to the present invention being able to be applied as an inhibitor which can directly inhibit YAP-TEAD binding in the Hippo pathway which plays a crucial role in the occurrence of cancer.

Abstract: A light modulation element and the use thereof are provided. The light modulation element can suppress a surface waviness phenomenon upon surface reflection visual observation by improving surface waviness of a base film caused by a spacer. Such light modulation element can be applied to various flexible display devices to improve the quality of products.

Abstract: Provided is a method for treating or preventing cancer, containing, as an active ingredient, a compound having a specific chemical structure and an activity of inhibiting the formation of a c-Myc/Max/DNA complex, or a pharmaceutically acceptable salt thereof.

Abstract: A transmittance-variable device is disclosed herein. In some embodiments, the transmittance-variable device includes a retardation film, a liquid crystal alignment film, and a liquid crystal layer configured to implement a twist orientation mode, wherein the retardation film, the liquid crystal alignment film and the liquid crystal layer are sequentially arranged, wherein a twist angle (T) is in a range of 50 degrees to 180 degrees, and wherein the smallest angle A between a slow axis of the retardation film and an alignment direction of the liquid crystal alignment film satisfies Equation 1 when a product (?nd) of a refractive index anisotropy (?n) and a thickness (d) is 0.7 ?m or less, and satisfies Equation 2 when the product (?nd) is more than 0.7 ?m. The transmittance-variable device can be applied to various applications without causing problems such as a crosstalk phenomenon, a rainbow phenomenon or a mirroring phenomenon.

Abstract: The present application relates to an optical element, a driving method of the optical element, a transmittance-variable device and a use thereof. In one example, the present application may provide a driving method suppressing a back-flow phenomenon caused by a bulk liquid crystal compound even when a cell gap of a liquid crystal layer becomes thick. The driving method may ensure excellent response speeds and driving characteristics.

Abstract: A transmittance-variable device is disclosed herein. In some embodiments, a transmittance-variable device includes first and second guest host layers, the first and second guest host layers are superposed, wherein each of the first and second guest host layers comprise a liquid crystal host and a dichroic dye guest, and wherein the device is capable of switching between a transparent mode and a black mode. The transmittance-variable device can exhibit high transmittance in the transparent state and a high shielding rate in the black state, and can exhibit a high contrast ratio even at the inclination angle, and exhibit excellent viewing angle symmetry in all directions. Such a transmittance-variable device can be applied to various applications including various architectural or automotive materials which need to adjust the transmittance, or eyewear such as goggles for augmented reality experience or sports, sunglasses or helmets.

Abstract: The present disclosure relates to a sensor network, Machine Type Communication (MTC), Machine-to-Machine (M2M) communication, and technology for Internet of Things (IoT). The present disclosure may be applied to intelligent services based on the above technologies, such as smart home, smart building, smart city, smart car, connected car, health care, digital education, smart retail, security and safety services. The present disclosure provides a method of determining information for building information modeling (BIM) by a BIM device.

Abstract: A transmittance-variable device is provided in the present application. The present application provides a transmittance-variable device, which can be applied to various applications without causing problems such as a crosstalk phenomenon, a rainbow phenomenon or a mirroring phenomenon, while having excellent transmittance-variable characteristics.

Abstract: The present disclosure relates to an oral tablet composition comprising lenalidomide and a method for preparing the same. More particularly, the present disclosure relates to a tablet-type composition and a method for preparing the same wherein the composition exhibits physicochemical equivalence with lenalidomide preparations of hard capsules, has the same pharmacological, therapeutic effect in non-clinical studies and bioequivalence studies, and also has improved ease of taking, handling, safety and the like.

Abstract: A light modulation element and the use thereof are provided. The light modulation element can suppress a surface waviness phenomenon upon surface reflection visual observation by improving surface waviness of a base film caused by a spacer. Such light modulation element can be applied to various flexible display devices to improve the quality of products.

Abstract: The present application relates to a method of manufacturing an optical device, an optical device and a use of the optical device. The method of manufacturing an optical device of the present application can form a patterned mold layer to maintain an appropriate gap between the upper and lower substrates, and can apply an imprinting process in patterning the mold layer to simply manufacture the mold pattern having the desired shape. In addition, the optical device manufactured by the above manufacturing method can have a low driving voltage and no short circuit phenomenon, and be realized as a flexible device. Such an optical device can be applied to various display devices such as LCDs.

Abstract: A transmittance-variable device is provided in the present application. The present application can provide a transmittance-variable device, which can be applied to various applications without causing problems such as a crosstalk phenomenon, a rainbow phenomenon or a mirroring phenomenon, while having excellent transmittance-variable characteristics.

Abstract: A light modulation device is disclosed herein. In some embodiments, a light modulation device includes a first polymer film substrate, a second polymer film substrate, an active liquid crystal layer disposed between the first and second polymer film substrates, wherein the active liquid crystal layer is capable of switching between a vertical orientation state and a twisting orientation state upon application of a voltage, each of the first and second polymer film substrates has an in-plane retardation of 4,000 nm or more for light having a wavelength of 550 nm, a ratio of an elongation (E1) in a first direction to an elongation (E2) in a second direction perpendicular to the first direction of 3 or more, and wherein an angle formed by the first directions of the first and second polymer film substrates is in a range of 0 degrees to 10 degrees.

Abstract: A transmittance-variable device is disclosed herein. In some embodiments, the transmittance-variable device includes a first guest host layer, a second guest host layer, and a phase difference element disposed between the first and second guest host layers, wherein each of the first and second guest host layers comprise a liquid crystal host and a dichroic dye guest, and the liquid crystal hosts are capable of being horizontally oriented such that their optical axes are horizontal to each other. The transmittance-variable device can switch between a clear state and a black state, can exhibit high transmittance in the clear state and a high shielding rate in the black state, and can exhibit a high contrast ratio even at the inclination angle. Such a transmittance-variable device can be used in architectural or automotive materials, or eyewear such as goggles for augmented reality experience or sports, sunglasses or helmets.

Abstract: The present application relates to a novel liquid crystal compound and a use thereof. The novel liquid crystal compounds of the present application can exhibit a smectic A phase over a wide temperature range. The novel liquid crystal compounds of the present application can be usefully used in the technical fields to which smectic A liquid crystals can be applied, for example, bistable devices.