Abstract: Provided herein are fusion proteins that comprise an enzyme replacement therapy enzyme and an Fc region, as well as methods of using such proteins to treat a lysosomal storage disorder. Methods for transporting agents across the blood-brain barrier are also provided herein.

Abstract: Poly(aryl piperidinium) polymers with pendant cationic groups are provided which have an alkaline-stable cation, piperidinium, introduced into a rigid aromatic polymer backbone free of ether bonds. Hydroxide exchange membranes or hydroxide exchange ionomers formed from these polymers exhibit superior chemical stability, hydroxide conductivity, decreased water uptake, good solubility in selected solvents, and improved mechanical properties in an ambient dry state as compared to conventional hydroxide exchange membranes or ionomers. Hydroxide exchange membrane fuel cells comprising the poly(aryl piperidinium) polymers with pendant cationic groups exhibit enhanced performance and durability at relatively high temperatures.

Abstract: The present invention belongs to the technical field of solder fluxes, and in particular relates to a water-soluble flux and a copper material pickling method. The water-soluble flux provided by the present invention includes an organic acid, an alcohol ether solvent, and deionized water. The organic acid is used as an active component of the present invention, and under the action of the alcohol ether solvent, oxides and impurities on the surface of a part to be welded can be sufficiently removed, and adhering residue of an acidic substance on the surface of the part to be welded can be reduced. In the process of tin plating of the part to be welded treated by the water-soluble flux provided by the present invention, the splash of tin liquid can be effectively inhibited, and the utilization rate of tin is improved.

Abstract: Poly(aryl alkylene) polymers or poly(aryl-crown ether-alkylene) polymers with pendant cationic groups are provided which have an alkaline-stable cation, such as imidazolium, introduced into a rigid aromatic polymer backbone free of ether bonds. Hydroxide exchange membranes or hydroxide exchange ionomers formed from these polymers exhibit superior chemical stability, hydroxide conductivity, decreased water uptake, good solubility in selected solvents, and improved mechanical properties in an ambient dry state as compared to conventional hydroxide exchange membranes or ionomers. Hydroxide exchange membrane fuel cells and hydroxide exchange membrane electrolyzers comprising the poly(aryl alkylene) polymers or poly(aryl-crown ether-alkylene) polymers with pendant cationic groups exhibit enhanced performance and durability at relatively high temperatures.

Abstract: Provided herein are fusion proteins that comprise an enzyme replacement therapy enzyme and an Fc region, as well as methods of using such proteins to treat a lysosomal storage disorder. Methods for transporting agents across the blood-brain barrier are also provided herein.

Abstract: Poly(aryl piperidinium) polymers are provided which have an alkaline-stable cation, piperidinium, introduced into a rigid aromatic polymer backbone free of ether bonds. Hydroxide exchange membranes or hydroxide exchange ionomers formed from these polymers exhibit superior chemical stability, hydroxide conductivity, decreased water uptake, good solubility in selected solvents, and improved mechanical properties in an ambient dry state as compared to conventional hydroxide exchange membranes or ionomers. Hydroxide exchange membrane fuel cells comprising the poly(aryl piperidinium) polymers exhibit enhanced performance and durability at relatively high temperatures.

Abstract: Poly(aryl piperidinium) polymers are provided which have an alkaline-stable cation, piperidinium, introduced into a rigid aromatic polymer backbone free of ether bonds. Hydroxide exchange membranes or hydroxide exchange ionomers formed from these polymers exhibit superior chemical stability, hydroxide conductivity, decreased water uptake, good solubility in selected solvents, and improved mechanical properties in an ambient dry state as compared to conventional hydroxide exchange membranes or ionomers. Hydroxide exchange membrane fuel cells comprising the poly(aryl piperidinium) polymers exhibit enhanced performance and durability at relatively high temperatures.

Abstract: A wireless power transmission system is provided for high power applications. The power transmission system is comprised generally of a charging unit configured to generate an alternating electromagnetic field and a receive unit configured to receive the alternating electromagnetic field from the charging unit. The charging unit includes a power source; an input rectifier; an inverter; and a transmit coil. The transmit coil has a spirangle arrangement segmented into n coil segments with capacitors interconnecting adjacent coil segments. The receive unit includes a receive coil and an output rectifier. The receive coil also has a spirangle arrangement segmented into m coil segments with capacitors interconnecting adjacent coil segments.

Abstract: A wireless power transmission system is provided for high power applications. The power transmission system is comprised generally of a charging unit configured to generate an alternating electromagnetic field and a receive unit configured to receive the alternating electromagnetic field from the charging unit. The charging unit includes a power source; an input rectifier; an inverter; and a transmit coil. The transmit coil has a spirangle arrangement segmented into n coil segments with capacitors interconnecting adjacent coil segments. The receive unit includes a receive coil and an output rectifier. The receive coil also has a spirangle arrangement segmented into m coil segments with capacitors interconnecting adjacent coil segments.

Abstract: A unified fresh search result serving approach that employs instant cache update. The instant result cache update efficiently updates the cache server instantly with the latest version of results in time. A unified cache service stores all related documents; thus, all information of a web document is saved on the same server to easily merge all the related information of web documents when generating captions for that document. Any update to web document content is immediately available in the result.

Abstract: This invention provides a family of cation-strung polymers capable of forming membranes having exceptional hydroxide ionic conductivity as well as low water uptake and methods of making the same. The invention also provides for using these cation-strung polymers to manufacture membranes useful in HEMFC fuel cells and other devices such as electrolysis, solar hydrogen generation, redox flow battery, dialysis, reverse osmosis, forward osmosis, pervaporation, ion exchange, sensor, and gas separation.

Abstract: A search engine can provide referencing information as context for a particular search result when an excerpt from the search result, comprising at least some similar elements to the user's query, is not generated. Referencing information can include one or more anchor texts having similarity to at least some elements of the user's query, the anchor texts being used by referencing pages to link to the page returned as a search result. User selection of the anchor text can enable the user to visit a referencing page using that anchor text to link to the page returned as a search result, and having a high static rank.

Abstract: A search engine can provide referencing information as context for a particular search result when an excerpt from the search result, comprising at least some similar elements to the user's query, is not generated. Referencing information can include one or more anchor texts having similarity to at least some elements of the user's query, the anchor texts being used by referencing pages to link to the page returned as a search result. User selection of the anchor text can enable the user to visit a referencing page using that anchor text to link to the page returned as a search result, and having a high static rank.

Abstract: Systems and methodologies for improved query classification and processing are provided herein. As described herein, a query prediction model can be constructed from a set of training data (e.g., diagnostic data obtained from an automatic diagnostic system and/or other suitable data) using a machine learning-based technique. Subsequently upon receiving a query, a set of features corresponding to the query, such as the length and/or frequency of the query, unigram probabilities of respective words and/or groups of words in the query, presence of pre-designated words or phrases in the query, or the like, can be generated. The generated features can then be analyzed in combination with the query prediction model to classify the query by predicting whether the query is aimed at a head Uniform Resource Locator (URL) or a tail URL. Based on this prediction, an appropriate index or combination of indexes can be assigned to answer the query.

Abstract: A provisioning system is described for dynamically and automatically allocating index server resources to different respective uses. For example, the provisioning system can allocate index server resources among different search-related production uses, different analysis-related uses, different testing-related uses, and so on. In one case, the provisioning system includes an allocation manager module that receives information that has a bearing on the allocation of index server resources. Based on this information, the allocation manager module determines an allocation of index server resources and sends instructions to an indexing system to carry out the allocation. In one case, the indexing system respond to the instructions by allocating rows of index server resources to different partner entities which have requested index server resources. Each row can also implement custom index information and/or custom processing functionality for use by particular partner entities.

Abstract: Systems, methods, computer-readable media, and graphical user interfaces for presenting search results having collapsed domains are provided. A search result obtaining module obtains search results based upon a received query. Upon obtaining the search results, search results having the same domain are associated with one another. Thereafter, search result clusters of associated search results are formed. In some embodiments, the search result clusters may be formatted to include desired search result cluster attributes. The search result clusters are presented such that two or more associated search results form a single cluster of search results rather than being presented individually. In some embodiments, an option to view more search results with the same domain may be provided.

Abstract: Methods, systems, and media are provided for synchronizing information across multiple environments of a synchronization system. A search query is received into a frontend infrastructure of a first synchronization environment. The frontend infrastructure checks a local cache manager to see if results already exist for the search query. If existing results are not found, then one or more backend search engines of the first synchronization environment are utilized for the search query. The search results from the backend search engines are saved into the local cache manager of the first synchronization environment. A cache sync notification is created to identify the contents and location of the actual saved results. The cache sync notification is saved in a cache synchronization service located within the first synchronization environment, and broadcast to all other synchronization environments within the synchronization system. The actual results can be retrieved from any other synchronization environment.

Abstract: Systems and methodologies for improved query classification and processing are provided herein. As described herein, a query prediction model can be constructed from a set of training data (e.g., diagnostic data obtained from an automatic diagnostic system and/or other suitable data) using a machine learning-based technique. Subsequently upon receiving a query, a set of features corresponding to the query, such as the length and/or frequency of the query, unigram probabilities of respective words and/or groups of words in the query, presence of pre-designated words or phrases in the query, or the like, can be generated. The generated features can then be analyzed in combination with the query prediction model to classify the query by predicting whether the query is aimed at a head Uniform Resource Locator (URL) or a tail URL. Based on this prediction, an appropriate index or combination of indexes can be assigned to answer the query.

Abstract: Systems, methods, computer-readable media, and graphical user interfaces for presenting search results having collapsed domains are provided. A search result obtaining module obtains search results based upon a received query. Upon obtaining the search results, search results having the same domain are associated with one another. Thereafter, search result clusters of associated search results are formed. In some embodiments, the search result clusters may be formatted to include desired search result cluster attributes. The search result clusters are presented such that two or more associated search results form a single cluster of search results rather than being presented individually. In some embodiments, an option to view more search results with the same domain may be provided.

Abstract: A system, method, computer-readable media, and related techniques are disclosed for presenting one or more search queries and at least one search result corresponding to at least one of the queries. In an embodiment, the method may include receiving a portion of a search query. In response to receiving at least a portion of the search query, the method may be configured to present to a user one or more suggested search queries and at least one predetermined search result corresponding to at least one of the one or more suggested queries. The method may further include presenting at least one advertisement corresponding to at least one or more suggested search queries.