Abstract: A filtration filter device according to the present invention includes a filtration filter that filters out a filtration object contained in a fluid and a housing in which the filtration filter is disposed. The housing includes a fluid inlet passage that faces one main surface of the filtration filter and a fluid outlet passage that faces the other main surface of the filtration filter. An inner peripheral surface of at least one of the fluid inlet passage and the fluid outlet passage is undulated.

Abstract: A concentration apparatus that includes a liquid tank storing a liquid containing a filtration object, a tubular member having first and second end portions disposed in the liquid tank and forming a first circulation flow path therebetween, a circulation pump for supplying the liquid stored in the liquid tank to flow from the first end portion to the second end portion, a filtration filter disposed in a sidewall of the tubular member, a bypass pipe having first and second ends thereof connected to sidewalls of the tubular member so as to form a second circulation flow path between the first and second end portions of the tubular member, a switching valve constructed to cause the liquid to flow in one of the first or second circulation flow paths, and a control unit controlling driving of the circulation pump and a switching operation of the switching valve.

Abstract: A filtration filter is suitable for performing cross-flow filtration by using a metallic porous membrane. A metallic porous membrane has a membrane portion for filtering filtration objects contained in a fluid and a held portion provided at its outer periphery. A first frame member and a second frame member hold the held portion of the metallic porous membrane there between. The held portion has a bent portion bent to a second principal surface side opposing a first principal surface of the membrane portion. The first frame member is in contact with the held portion at the first principal surface side of the metallic porous membrane. The second frame member is disposed at an inner side portion of the first frame member and is in contact with the held portion at the second principal surface side of the metallic porous membrane.

Abstract: A filtration method for filtration of nucleated cells that includes providing a filter containing at least one of a metal and a metal oxide as a major component thereof and having a plurality of through-holes therein, and passing a liquid containing the nucleated cells through the filter. The diameter of an inscribed circle of each of the plurality of through-holes is smaller than the size of the nuclei of the nucleated cells, and the inscribed circle of each of the plurality of through-holes touches all sides defining an opening of the through-hole.

Abstract: A filtration filter device that enables an object filtered and left on a filtration filter to be more readily observed is provided. The filtration filter device includes a filtration filter that filters an object contained in a fluid, a holding member that holds an outer circumferential portion of the filtration filter, and a tubular member that is removably mounted on the holding member such that a hollow portion that serves as a channel through which the fluid flows faces at least a part of a main surface of the filtration filter.

Abstract: A filtration method for filtration of nucleated cells that includes providing a filter containing at least one of a metal and a metal oxide as a major component thereof and having a plurality of through-holes therein, and passing a liquid containing the nucleated cells through the filter. The diameter of an inscribed circle of each of the plurality of through-holes is smaller than the size of the nuclei of the nucleated cells, and the inscribed circle of each of the plurality of through-holes touches all sides defining an opening of the through-hole.

Abstract: In an artificial defect material 10 of an FRP structure, a heat-resistant high-linear-expansion material 20 arranged between the layers thermally expands in case of high-temperature shaping of the FRP structure, so that a predetermined shape is shaped between a plurality of layers of the fiber reinforcing base material 14 and the material 20 thermally shrinks at the room temperature after the shaping, so that a space is formed due to the shrinkage difference from the fiber reinforcing base materials 14. The material 20 has a linear expansion coefficient larger than that of the FRP structure by a predetermined value or more, and has the shape keeping property and the heat resistance to endure the shaping temperature.

Abstract: A liquid cell culture medium collecting filter unit includes a porous metal membrane that filters out cells in a liquid cell culture medium, a support that holds a peripheral portion of the porous metal membrane. and a tubular member that has a hollow part serving a flow path for a liquid cell culture medium. The tubular member is connected to the support such that the flow path faces at least part of a main surface of the porous metal membrane.

Abstract: A cell filtration filter that includes a metal membrane part that has a first main surface on which the cells are to be captured and a second main surface that opposes the first main surface. The metal membrane part has a plurality of hole edges that define a plurality of first through holes and a support region that is arranged around the hole edges and supports the hole edges. In the support region of the metal membrane part, a plurality of second through holes, which have smaller openings than the first through holes, are arranged so as to surround the hole edges. On the first main surface of the membrane part, the hole edges are raised with respect to the support region.

Abstract: A sampling filter and a sampling device that can readily sample cell aggregates having a predetermined size are provided, and a sampling method using the same is provided. A sampling filter samples cell aggregates and includes a frame portion that demarcates a region through which a liquid containing cell aggregates passes and a filter portion which is disposed in only part of the region and in which a plurality of through holes are located.

Abstract: A filtration filter device that includes a filtration filter that filters an object to be filtered that a fluid contains, and a holding member that holds an outer circumferential portion of the filtration filter. An annular projecting portion that projects in a thickness direction of the holding member and that defines a channel through which the fluid flows is formed on one main surface of the holding member. A recessed portion that is recessed in the thickness direction of the holding member and that has an inner diameter larger than an inner diameter of the projecting portion is formed on the other main surface of the holding member. The filtration filter is disposed inside the projecting portion of the holding member.

Abstract: In a cell-capturing filter including a metal porous membrane, degradation over time is determined earlier. A cell-capturing filter includes a metal porous membrane having a plurality of through-holes that penetrate between two principal surfaces facing each other. The metal porous membrane is made of an alloy of nickel and an element selected from the group consisting of gold, platinum, and palladium, or a metal containing nickel as a main component. A metal containing copper as a main component is attached to a part of either one of the principal surfaces of the metal porous membrane.

Abstract: A filtration filter device that enables the sealability of a fluid channel to be improved is provided. A filtration filter device according to the present invention includes a first channel-forming member that has a first channel through which a fluid flows inside thereof, a second channel-forming member that has a second channel through which a fluid flows inside thereof, and a filtration filter that extends across the first channel or the second channel and that filters an object to be filtered that the fluid contains. The first channel-forming member includes an external thread. The second channel-forming member includes an internal thread.

Abstract: A filtration method for filtration of nucleated cells that includes providing a filter containing at least one of a metal and a metal oxide as a major component thereof and having a plurality of through-holes therein, and passing a liquid containing the nucleated cells through the filter. The diameter of an inscribed circle of each of the plurality of through-holes is smaller than the size of the nuclei of the nucleated cells, and the inscribed circle of each of the plurality of through-holes touches all sides defining an opening of the through-hole.

Abstract: A filtration filter device that enables an object filtered and left on a filtration filter to be more readily observed is provided. The filtration filter device includes a filtration filter that filters an object contained in a fluid, a holding member that holds an outer circumferential portion of the filtration filter, and a tubular member that is removably mounted on the holding member such that a hollow portion that serves as a channel through which the fluid flows faces at least a part of a main surface of the filtration filter.

Abstract: A filtration filter that filters a filtration target contained in a fluid. The filtration filter includes a porous metal film having a plurality of through holes. Moreover, wave-shaped irregularities are provided in a peripheral direction along inner peripheral surfaces of the through holes of the porous metal film.

Abstract: A metallic porous membrane that classifies cell aggregates includes a membrane section having a first principal surface for capturing the cell aggregates, a second principal surface opposing the first principal surface, and a plurality of through-holes communicating with the first principal surface and the second principal surface.

Abstract: A filter for filtering nucleated cells that includes a body containing at least either a metal or a metal oxide as its main component; and plural through holes, each of which have a shape other than a square shape, formed therein. A longitudinal diameter of an inscribed ellipse within each of the through holes is smaller than a size of a nucleus of each of the nucleated cells to be filtered. The inscribed ellipse of the through hole is an ellipse that abuts all sides that define an opening of the through hole.

Abstract: A filter includes a plurality of first through holes which are periodically formed. At least one of the plurality of first through holes is divided by a plurality of second through holes that are smaller than the first through holes. With such a configuration, the cell aggregate having the desired size can be easily sampled.

Abstract: A filtration filter device according to the present invention includes a filtration filter that filters out a filtration object contained in a fluid and a housing in which the filtration filter is disposed. The housing includes a fluid inlet passage that faces one main surface of the filtration filter and a fluid outlet passage that faces the other main surface of the filtration filter. An inner peripheral surface of at least one of the fluid inlet passage and the fluid outlet passage is undulated.