Abstract: Methods of treating tumor cells in an individual comprise administering to the individual a drug having anti-tumor effect, wherein the drug is delivered into the tumor cells via Right-Handed Coiled-Coil (RHCC) protein or a fragment or variant thereof. The drug may, for example, be a metal-containing compound, a protein or peptide drug, and/or an organic hydrophobic compound.

Abstract: A system and process for monitoring the valves of an anesthetic dispenser with a safety valve (2) and with a dispensing valve (3) for dispensing the anesthetic in the form of a vapor. The valves are connected in series. A system has a downstream dispensing gap (5) and a fixed bypass resistance (9). The dispensing valve (3) is first opened for an equalization time. The safety valve (2) and the dispensing valve (3) are closed and the differential pressure between the saturated vapor branch (4) and the mixed gas branch (8) is measured by means of a differential pressure sensor (6, 7). The safety valve (2) or the dispensing valve (3) is opened and the differential pressure between the saturated vapor branch (4) and the mixed gas branch (8) is measured by means of the differential pressure sensor (6, 7).

Abstract: The invention relates to a high-power pulsed magnetron sputtering process (1), wherein within a process chamber (2) by means of an electrical energy source (3) a sequence of complex discharge pulses (4) is produced by applying an electrical voltage (V) between an anode (5) and a cathode (6) in order to ionize a sputtering gas (7). Said complex discharge pulse (4) is applied for a complex pulse time (?). The cathode (6) has a target (8) comprising a material to be sputtered for the coating of a substrate (9), and said complex discharge pulse (4) includes an electrical high-power sputtering pulse (10) having a negative polarity with respect to the anode (5) and being applied for a first pulse-time (?1), the high-power sputtering pulse (10) being followed by an electrical low-power charge cleaning pulse (11) having a positive polarity with respect to the anode (5) and being applied for a second pulse-time (?2).

Abstract: The invention relates to a reagent cartridge for receiving containers. These each contain particle-charged reagents and particle-free reagents. The container receiving the particle-charged reagent is received so as to be able to rotate. The reagent cartridge comprises interconnectable cartridge parts which form containers and which, in the interconnected state, ensure that the container receiving the particle-charged reagent is mounted so as to be able to rotate.

Abstract: The invention relates to a method for fabricating a steel strip (1), in which firstly a slab (3) is cast in a caster (2), with the slab (3) exiting the caster (2) at a casting speed (v) with a given slab thickness (H), with the slab (3) then being rolled to form a strip (1) in at least one rolling train (4, 5) having a number of rolling stands (6, 7) and the strip (1) having a final thickness (dE) downstream of the last rolling stand (6, 7).

Abstract: A device for mixing anesthetic vapor with anesthetic gas has a pressure limitation feature achieved in a simple manner. The device has a valve device (11), with which the evaporator is switched on and off. The valve device (11) is equipped with an overpressure release device (22).

Abstract: The invention relates to a method of carrying out measurements with penetrating radiation on a hollow object comprising at least one wall surrounding an inner space of the object, said wall comprising an inner surface and an outer surface, said method at least being carried out for determining a position and shape of at least a portion of the inner surface of the wall.

Abstract: An imaging tomography apparatus, in particular an x-ray tomography apparatus or an ultrasound tomography apparatus, has a stationary unit with a sensor for measurement of an out-of-balance condition of an annular data acquisition device rotatable around a patient opening in the stationary device. Compensation weights for compensation of the out-of-balance condition are provided on the data acquisition device. To simplify the balancing procedure, the compensation weights are disposed in two parallel planes axially separated from one another, and in each plane at least three compensation weights are fashioned as chambers that can be filled with a fluid. At least two of the chambers are connected with one another via at least one conduit for fluid transfer therebetween exchange.

Abstract: A device is provided for measuring the differential pressure in anesthetic dispensing devices, with which the differential pressure can be measured between two lines (2, 6) for supplying gaseous components to a mixing site (3). The device has at least one differential pressure sensor (11), which is connected with the lines (2, 6) for supplying the gaseous components. Buffer elements (12, 12?) are integrated in the connection between the lines (2, 6) for supplying the gaseous components and the differential pressure sensor (11).

Abstract: A device for the support and oscillation of a continuous casting mould (1) for casting liquid metal, particularly liquid steel, comprising guide elements (4) which are mounted on fixed carrier components (5) and which is actually by means of oscillation devices (6). In order to shorten time required for mounting and dismounting and therefor to lower the down times and costs of said continuous casting device, a first module (7) is made of guide elements (4) and carrier components (5) and a second module (8) consists of the oscillation device (6). The second module (8) can be dismantled via an outlet (9) which extends laterally, perpendicular to the plane of symmetry (2) below the guide elements (4) or in between guide elements (4). Each of the two modules (7,8) can be dismounted or re-mounted in a manner which is temporally and locally independent from the other respective module (7,8).

Abstract: An anesthetic evaporator with a pressure control circuit has a differential pressure pick-up (18) can be calibrated in a simple manner. A switchover device (20) is provided according to the present invention at a bypass gap (3), which is designed to connect the gas inlet (4) directly with the gas outlet (5) via a first bypass line (23) and to bridge over the bypass gap (3) via a second bypass line (26) connected to a ventilation duct (27) in a first switching position. The gas flow from the gas inlet (4) to the gas outlet (5) is established via the bypass line (2) in a second switching position. The calibration of the differential pressure pick-up (18) with the pneumatic connections (16, 17) is performed in the first switching position of the switchover means (20) via the ventilation duct (27), which is open toward the ambient atmosphere.

Abstract: An optical measurement device for measurement of chemical and/or biological samples comprises an illumination means (16) for illuminating the sample (20) to be measured. Further, an optics means (22) is provided for imaging a sample area in an image field (10). A first partial area (12) of the image field is covered by a first detector (28), and a second partial area (14) of the image field (10) is covered by a second detector (34). Thus, it is possible to change between two measurement methods without switching or to perform two measurements on a sample at the same time.

Abstract: A device for measuring the optical properties of an object, particularly of a chemical and/or biological sample, comprises an illumination light source for illuminating the object. Further, an excitation light source is provided for illuminating the object, wherein the radiation of the excitation light source being suited to change the optical properties of the object. Further, the excitation radiation is focused in a measurement volume arranged within the object. By means of a detector device, there can be detected preferably the transmission of the illumination radiation through the object within the measurement volume.

Abstract: The invention relates to one-component aqueous dispersion adhesives containing at least one copolymer A of monomers ethylene, vinyl acetate and, optionally, at least one (meth)acrylate and either at least one polyurethane with carboxyl groups and carbodiimide groups PUR-COOH-CDI or a mixture of a polyurethane with carboxyl groups PUR-000H and with a carbodiimide CDI. These dispersion adhesives are particularly well-suited for use as laminating adhesives and sealing adhesives. The invention also relates to the precoating of flat materials with a one-component aqueous dispersion adhesive.

Abstract: A gantry for a computed tomography apparatus has a rotary carriage that is rotatable around an axis and a support ring arranged around the rotary carriage with a circumferential cooling channel. The support ring has a number of openings distributed around its circumference and forming a non-uniform opening pattern. The rotary carriage likewise has inflow and outflow openings that, in operation, overlap the openings on the stationary part of the computed tomography apparatus such that a coolant flows through between the support ring and the rotary carriage. A steady pressure fluctuation that leads to a reduction of the noise stress in operation ensues thanks to the non-uniform opening pattern.

Abstract: An alarm is associated with a device for dispensing volatile anesthetics. The alarm and device is designed such that an alarm is triggered whenever the operating voltage is interrupted and an assembly unit that determines the dispensing of at least one anesthetic is not in a prescribed state of operation.

Abstract: A cooling system is provided for components of a computer tomography system that are arranged in a gantry housing. The cooling system includes a cooled air feed device with an air compressor and connected streaming elements that are arranged and/or fashioned such that compressed air flows onto the components to be cooled. Moreover, a corresponding method is provided for cooling the components of a computer tomography system arranged in a gantry housing.

Abstract: A confocal microscope has a specimen holding device for holding a specimen (18). The specimen (18) is illuminated by an illuminating unit (10). An optics unit (12) serves to direct radiation produced by the illuminating unit (10) toward the specimen (18) and to direct the radiation emitted by the specimen toward a detector unit (20). The confocal microscope also comprises an aperture diaphragm (34) that is placed in the beam path in front of the detector unit (20). In addition, a focusing lens (30) is provided in the beam path in front of the aperture diaphragm (34). The focusing lens (30) can be moved in order to adjust the confocal microscope, for example, in order to compensate for thermal stresses.

Abstract: A filling device for an anesthetic evaporator has filling of an anesthetic evaporator is possible. To accomplish the object, an additional vent hole (36), which is opened immediately after the filling in order for excess anesthetic volume to be able to flow out of the filling device into the anesthetic tank (15) of the anesthetic evaporator (2), is provided within the filling device above a fluid channel (14), via which both the gas and liquid exchange takes place during the filling.

Abstract: An anesthetic tank (1) of an anesthetic dispensing unit is used especially for desflurane and has improved reliability of operation by mutually complementing level monitoring devices. The anesthetic tank (1) is equipped with a level tube (3) arranged in or on the outer wall with a connection line (6) into the interior space as well as with an optical level sensor (4). The optical axis (5) of the level sensor (4) is located at the same level as a mark (33) on the level tube (3).