Abstract: A system and method for characterising a narrowing in a fluid filled tube, the system comprising: a probe having a first measurement sensor to take an instantaneous measurement at different locations along the tube; a mechanism to draw the probe through the tube; a position measure to provide location data relating to the location at which a respective instantaneous measurement is taken by the first measurement sensor; a processor to calculate, from the instantaneous measurements, a characteristic of the tube at different locations along the tube.

Abstract: A coronary wire for insertion through a catheter into a coronary vessel of a patient, the wire having: a working length miming from a proximal end for connection with a connector to a distal end for insertion through a catheter into a coronary vessel of a patient; a flexible length, a portion of which is exposed, in use, from the catheter and able, in use, to make contact with the coronary vessel; a distal tip at the distal end; an electrode on the flexible length at the distal tip or offset from the distal tip by a predetermined spacing; and electrical insulation electrically insulating the exposed portion of the flexible length of the wire except at the electrode at the distal end to allow the electrode to electrically contact the coronary vessel.

Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed. In some instances, a method of evaluating a vessel of a patient includes moving a second instrument longitudinally through a vessel of the patient from a first position to a second position while maintaining a first instrument in a fixed longitudinal position with respect to the vessel; obtaining pressure measurements from the first and second instruments while the second instrument is moved longitudinally through the vessel; visually depicting the vessel on a display based on the obtained pressure measurements; and modifying the visual depiction of the vessel to simulate one or more treatment options. Systems for performing such methods are also provided.

Abstract: We provide an imaging system for use in a fluoroscopy procedure carried out on a subject, the imaging system being configured to receive images of a portion of the subject from an image acquisition device, the imaging system comprising an interface module for displaying images received from the image acquisition device to a user, and an optimisation module for determining, based on an image received from the image acquisition device, one or more properties of the image, wherein the optimisation module is configured to output a control routine.

Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent.

Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent.

Abstract: A medical intervention control system for providing a risk analysis and influencing intervention action on a patient, the system comprising: a database with a data set containing data from at least one data source comprising: a) study data; and b) sensed data; a waveform detector operable to identify a waveform from a data source, extract the waveform, categorise the waveform, normalise the waveform to a predetermined format and determine waveform characteristics and parameters of the waveform, the waveform detector populating part of the sensed data; a measurement module to derive subject data from the patient; an analyser operable to analyse the subject data with respect to the data set from the at least one data source and output an associated probability for each of one or more outcomes, wherein the associated probability is affected by an intervention, wherein the analyser takes subject data derived from the patient and tests for outcomes and potential interventions which influence the outcomes; an actio

Abstract: A cleaning tool is provided. The cleaning tool integrates a Swedish sponge clothe material and a woven fabric material joined through a durable attachment.

Abstract: An apparatus and method of assessing a narrowing in a fluid filled tube having a fluid flow pressure wave having a backward-originating pressure component and a forward-originating pressure component without taking a flow velocity measurement, comprising: taking pressure measurements in the tube; separating the pressure components into the backward-originating pressure component and the forward-originating pressure component; identifying a time window when the differential of flow velocity (dU) is minimal or absent; and deriving the backward and forward pressure components for pressure measurements taken in at least the time window.

Abstract: An apparatus and method of assessing a narrowing in a fluid filled tube having a fluid flow pressure wave having a backward-originating pressure component and a forward-originating pressure component without taking a flow velocity measurement, comprising: taking pressure measurements in the tube; separating the pressure components into the backward-originating pressure component and the forward-originating pressure component; identifying a time window when the differential of flow velocity (dU) is minimal or absent; and deriving the backward and forward pressure components for pressure measurements taken in at least the time window.

Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed.

Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed.

Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed.

Abstract: Devices, systems, and methods configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel, provide visual depictions of vessel that allow assessment of the vessel and, in particular, any stenosis or lesion of the vessel, simulate one or more treatment options for the vessel, and perform treatment on any stenosis or lesion of the vessel, including guiding placement of one or more treatment devices are provided. The method can include obtaining pressure measurements from first and second instruments positioned within a vessel of a patient during a diagnostic procedure where the second instrument is moved longitudinally through the vessel; identifying a treatment option based on the obtained pressure measurements; and performing the identified treatment option, wherein a user display guides placement of one or more treatment devices associated with the identified treatment option.

Abstract: The present disclosure relates generally to the assessment and treatment of vessels, including for percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). For example, some embodiments of the present disclosure are suited for identifying the available intervention technique(s) suitable to achieve a desired outcome selected or input by a user. For example, in some implementations a method comprises receiving pressure measurements obtained by one or more intravascular pressure-sensing instruments positioned within a vessel of a patient; receiving an input from a user regarding a desired pressure value for the vessel of the patient; identifying an available treatment option based on the received pressure measurements and the desired pressure value; and outputting, to a display device, a screen display including a visual representation of the available treatment option. Related devices and systems are also described.

Abstract: An apparatus and method of assessing a narrowing in a fluid filled tube having a fluid flow pressure wave having a backward-originating pressure component and a forward-originating pressure component without taking a flow velocity measurement, comprising: taking pressure measurements in the tube; separating the pressure components into the backward-originating pressure component and the forward-originating pressure component; identifying a time window when the differential of flow velocity (dU) is minimal or absent; and deriving the backward and forward pressure components for pressure measurements taken in at least the time window.

Abstract: An apparatus and method of assessing a narrowing in a fluid filled tube having a fluid flow pressure wave having a backward-originating pressure component and a forward-originating pressure component without taking a flow velocity measurement, comprising: taking pressure measurements in the tube; separating the pressure components into the backward-originating pressure component and the forward-originating pressure component; identifying a time window when the differential of flow velocity (dU) is minimal or absent; and deriving the backward and forward pressure components for pressure measurements taken in at least the time window.

Abstract: An apparatus and method of assessing a narrowing in a fluid filled tube having a fluid flow pressure wave having a backward-originating pressure component and a forward-originating pressure component without taking a flow velocity measurement, comprising: taking pressure measurements in the tube; separating the pressure components into the backward-originating pressure component and the forward-originating pressure component; identifying a time window when the differential of flow velocity (dU) is minimal or absent; and deriving the backward and forward pressure components for pressure measurements taken in at least the time window.

Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent.

Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent.