Abstract: The present invention is directed to a new fluoro-pyridinone hydroxamic acid phosphates and boronates of Formulae I, II and III wherein Q is selected from the group consisting of —P(O)(OH)2, —P(O)(OH)(O?M+), —P(O)(O?M+)2 and —P(O)(O?)2M2+; M+ at each occurrence is a pharmaceutically acceptable monovalent cation; and M2+ is a pharmaceutically acceptable divalent cation and their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: A method implemented through a data processing device of a computing network including includes detecting a point anomaly in real-time data associated with each network entity based on determining whether the real-time data falls outside a threshold expected value thereof, and representing the detected point anomaly in a full mesh Q node graph, with Q being a number of features applicable for the each network entity. The method also includes capturing a transition in the point anomaly associated with a newly detected anomaly or non-anomaly in the real-time data associated with one or more of the Q number of features via the representation of the full mesh Q node graph, and deriving a current data correlation score for the point anomaly across the captured transition via the representation of the full mesh Q node graph.

Abstract: The present disclosure is directed to a coated metal substrate comprising a metal substrate; a coating applied over at least a portion of the metal substrate, wherein the coating comprises a film-forming binder; magnesium oxide; and an aluminum compound and/or iron compound; wherein the coating has a dry film thickness of at least 10 microns, and the magnesium oxide and the aluminum and/or iron compound are present in a weight ratio of 1:1 to 240:1. The present disclosure is also directed to a curable film film-forming coating composition a film-forming binder; magnesium oxide; and an aluminum compound and/or iron compound, wherein the magnesium oxide and the aluminum and/or iron compound are present in a weight ratio of 1:1 to 240:1. Also disclosed are methods of coating a substrate.

Abstract: A solid-state thermal battery system is disclosed herein. The system includes a stationary thermal storage medium that can be charged by adding heat to the thermal storage medium. Actuated heat engines can be utilized to discharge the solid-state thermal battery, converting the heat stored in the thermal storage medium into electricity. The heat engines are actuated in a manner that reduces thermal gradients in the thermal storage medium to increase the efficiency of the system. In one embodiment, the thermal storage medium is contained in a main chamber of an insulated container. The heat engines are stored, when idle, in an ancillary chamber adjacent to the main chamber and moved into the main chamber by an actuation system to begin discharging the solid-state thermal battery. The heat engines follow a path during discharge to dynamically move between regions of the thermal storage medium to reduce thermal gradients induced therein.

Abstract: Continuous compression molding machines (CCMMs) and methods of continuous compression molding a consolidated thermoplastic matrix composite material are disclosed herein. The CCMMs include a mold, a heat zone heating structure, a consolidation zone heating structure, and a stress relaxation zone heating structure. The CCMMs also include a press structure, a demold structure, and a supply structure. The methods include providing a thermoplastic matrix composite material (TMCM) that includes a thermoplastic material to a CCMM. During the providing, the methods also include heating the TMCM within a heat zone of the CCMM, cooling and consolidating the TMCM within a consolidation zone of the CCMM, relaxing stress within the TMCM within a stress relaxation zone of the CCMM, demolding the TMCM within a demold zone of the CCMM at a mold temperature that is greater than a glass transition temperature of the thermoplastic material, and periodically compressing the TMCM.

Abstract: A bioinformatics pipeline designed to analyze next generation sequence data as input and systematically quality filter, normalize, annotate, quantify, and identify microbial taxa of interest contained within microbial databases. In various embodiment, a bioinformatics pipeline may include a deep annotation strategy that confers an additional task that can be scaled to a limitless number of taxa of interest each time a taxa of interest is extracted for re-annotation.

Abstract: Systems and methods for building passive and active electronics with diamond-like carbon (DLC) coatings are provided herein. DLC may be layered upon substrates to form various components of electronic devices. Passive components such as resistors, capacitors, and inductors may be built using DLC as a dielectric or as an insulating layer. Active components such as diodes and transistors may be built with the DLC acting substantially like a semiconductor. The amount of sp2 and sp3 bonded carbon atoms may be varied to modify the properties of the DLC for various electronic components.

Abstract: A cover for an ultrasound scanning assembly is provided, wherein the cover exerts compressive force on the patient during use. The cover includes an outer frame and a nonporous or porous film extending across the outer frame. The outer frame is formed of a soft touch material.

Abstract: A hydraulic pump or motor includes a mounting flange that is disposed at the first end of the housing. The mounting flange defines a pair of bolt receiving slots that are disposed along the X-axis on either side of the shaft. The pair of bolt receiving slots each define a radius center that are spaced away from each other a X dimension, and a pilot projection extends longitudinally away from the mounting flange, defining a pilot projection diameter. A ratio of the X dimension to the pilot projection diameter ranges from 1.1 to 1.5.

Abstract: A circuit board assembly includes a circuit board and an electrical connector having a connector housing holding contacts in a contact array. The connector housing has a mating end configured to be mated with a mating electrical connector in a mating direction. The electrical connector has cables terminated to the contacts and extending from a cable end. A connector mount is used to locate the electrical connector relative to the circuit board. A bracket is coupled to the mounting surface of the circuit board. A biasing member is coupled to the bracket and the mounting feature and is compressible along a compression axis parallel to the mating direction to allow the electrical connector to float in the mating direction relative to the circuit board.

Abstract: Provided are methods, compositions and kits for depleting host nucleic acid in a biological sample, said sample having been previously obtained from an animal host.

Abstract: Acoustic echo cancellation systems and methods are provided that improve the quality of the audio transmitted from by an audio device a near end to a far end when a doubletalk condition is present, including allowing certain subbands of an echo-cancelled signal to be less attenuated by overriding certain gains of subbands of the echo-cancelled audio signal in a non-linear processor, and compressing and applying makeup gain to a remote audio signal.

Abstract: Traffic signal timing plans are derived from vehicle trajectory or probe data. The probe data is collected and archived in a datastore over a sample time on the order of weeks or longer. Probe data is corrected for clock drift, geo-fence filtered to a selected intersection, and then stop line crossings in the intersection are identified and analyzed along with related data to determine the timing plans and schedule for the intersection. In this way, access to government agency timing plans is obviated so as to save time and expense.

Abstract: Certain aspects of the present disclosure provide a system for processing data, comprising a plurality of processing nodes, each processing node comprising at least one processor and at least one radio frequency (RF) chain and at least one link for conductive RF communication between or among the processing nodes using a wireless communications protocol.

Abstract: A computer-implemented method for providing landmark-assisted navigation guidance by selectively utilizing database information includes receiving navigation requests from one or more mobile computing devices, each of the requests being associated with a respective starting point, destination, and travel mode. For each navigation request, a corresponding route to be depicted in a corresponding digital map is determined. For each navigation request associated with a first travel mode, corresponding points of interest (POIs) are determined from among a plurality of POIs stored in a database. The corresponding POIs are determined based at least on whether the corresponding POIs are associated with any landmark category. For each navigation request associated with a second travel mode, corresponding POIs are determined irrespective of whether the corresponding POIs are associated with any landmark categories.

Abstract: A circuit board assembly includes an electrical connector mounted to a circuit board having a connector housing holding contacts in a contact array. A connector mount having a bracket is coupled to the mounting surface of the circuit board proximate to the mating edge. The electrical connector is movably coupled to the connector mount to move relative to the circuit board during mating with the mating electrical connector. The connector mount has a biasing member compressible along a compression axis parallel to the mating direction to allow the electrical connector to float in the mating direction relative to the circuit board. The electrical connector is movably coupled to the connector mount in a confined envelope in at least one floating direction perpendicular to the mating direction.

Abstract: A method implemented through a server of a cloud computing network including subscribers of application acceleration as a service provided therethrough includes detecting a point anomaly in real-time data associated with each network entity based on determining whether the real-time data falls outside a threshold expected value thereof, and representing the detected point anomaly in a full mesh Q node graph, with Q being a number of features applicable for the each network entity. The method also includes capturing a transition in the point anomaly associated with a newly detected anomaly or non-anomaly in the real-time data associated with one or more of the Q number of features via the representation of the full mesh Q node graph, and deriving a current data correlation score for the point anomaly across the captured transition via the representation of the full mesh Q node graph.

Abstract: Continuous compression molding machines (CCMMs) and methods of continuous compression molding a consolidated thermoplastic matrix composite material are disclosed herein. The CCMMs include a mold, a heat zone heating structure, a consolidation zone heating structure, and a stress relaxation zone heating structure. The CCMMs also include a press structure, a demold structure, and a supply structure. The methods include providing a thermoplastic matrix composite material (TMCM) that includes a thermoplastic material to a CCMM. During the providing, the methods also include heating the TMCM within a heat zone of the CCMM, cooling and consolidating the TMCM within a consolidation zone of the CCMM, relaxing stress within the TMCM within a stress relaxation zone of the CCMM, demolding the TMCM within a demold zone of the CCMM at a mold temperature that is greater than a glass transition temperature of the thermoplastic material, and periodically compressing the TMCM.

Abstract: Techniques are described herein for audio processing. For instance, a technique can include receiving, from one or more microphones, an audio signal; receiving a periodic timing signal based on the periodic timing signal; combining the audio signal and the periodic timing signal into an audio stream; generating a time stamp based on the received periodic timing signal; and adding the generated time stamp to the audio stream based on the periodic timing signal in the audio stream.

Abstract: The disclosure herein describes an emotional insight management system that provides user-configured prompts and insights to the user. In some examples, an insights application provides personalized, recurring prompts to encourage users to provide current emotional state updates to a well-being journal. The user's responses over time are aggregated within a historical trends report, which provides emotional response data over time. The insights application generates insights into potential reasons for the user's emotional states on a given day. The system analyzes the user-provided emotion response data with integrated work-related data to identify reasons for the user's mood and make recommendations for actions to be taken by users to reduce stress and improve the user's emotional well-being.