Patents by Inventor Justin M. Lira
Justin M. Lira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220290175Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.Type: ApplicationFiled: May 23, 2022Publication date: September 15, 2022Inventors: Terry R. WRIGHT, Justin M. LIRA, Terence Anthony WALSH, Donald MERLO, Jayakumar Pon SAMUEL, Gaofeng LIN
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Patent number: 11371055Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.Type: GrantFiled: March 24, 2017Date of Patent: June 28, 2022Assignee: Corteva Agriscience LLCInventors: Terry R. Wright, Justin M. Lira, Terence Anthony Walsh, Donald Merlo, Jayakumar Pon Samuel, Gaofeng Lin
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Patent number: 10913955Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.Type: GrantFiled: October 3, 2018Date of Patent: February 9, 2021Assignee: Dow AgroSciences LLCInventors: Javier A. Delgado, Justin M. Lira, Michael T. Sullenberger, Robert Cicchillo
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Patent number: 10876131Abstract: DIG-303 insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.Type: GrantFiled: October 30, 2015Date of Patent: December 29, 2020Assignee: DOW AGROSCIENCES LLCInventors: Meghan L. F. Frey, Justin M. Lira, Xiaoping Xu, Ignacio Mario Larrinua, Kenneth Narva, Timothy D Hey
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Publication number: 20200385751Abstract: The subject invention relates to a novel gene referred to herein as DSM-2. This gene was identified in Streptomyces coelicolor A3. The DSM-2 protein is distantly related to PAT and BAR. The subject invention also provides plant-optimized genes encoding DSM-2 proteins. DSM-2 can be used as a transgenic trait to impart tolerance in plants and plant cells to the herbicides glufosinate and bialaphos. One preferred use of the subject genes are as selectable markers. The use of this gene as a selectable marker in a bacterial system can increase efficiency for plant transformations. Use of DSM-2 as the sole selection marker eliminates the need for an additional medicinal antibiotic marker (such as ampicillin resistance) during cloning. Various other uses are also possible according to the subject invention.Type: ApplicationFiled: August 20, 2020Publication date: December 10, 2020Applicant: Dow AgroSciences LLCInventors: Justin M Lira, Terry Wright, Andrew E. Robinson, Sean Russell, Donald J Merlo, Steven Webb, Nicole L Arnold, Kelley E Smith
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Publication number: 20200385752Abstract: The subject invention relates to a novel gene referred to herein as DSM-2. This gene was identified in Streptomyces coelicolor A3. The DSM-2 protein is distantly related to PAT and BAR. The subject invention also provides plant-optimized genes encoding DSM-2 proteins. DSM-2 can be used as a transgenic trait to impart tolerance in plants and plant cells to the herbicides glufosinate and bialaphos. One preferred use of the subject genes areas selectable markers. The use of this gene as a selectable marker in a bacterial system can increase efficiency for plant transformations. Use of DSM-2 as the sole selection marker eliminates the need for an additional medicinal antibiotic marker (such as ampicillin resistance) during cloning. Various other uses are also possible according to the subject invention.Type: ApplicationFiled: August 20, 2020Publication date: December 10, 2020Applicant: Dow AgroSciences LLCInventors: Justin M Lira, Terry Wright, Andrew E. Robinson, Sean Russell, Donald J Merlo, Steven Webb, Nicole L Arnold, Kelley E Smith
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Patent number: 10752913Abstract: The subject invention relates to a novel gene referred to herein as DSM-2. This gene was identified in Sterptomyces coelicolor A3. The DSM-2 protein is distantly related to PAT and BAR. The subject invention also provides plant-optimized genes encoding DSM-2 proteins, DSM-2 can be used as a transgenic trait to impart tolerance in plants and plant cells to the herbicides glufosinate and bialaphos. One preferred use of the subject genes are as selectable markers. The use of this gene as a selectable marker in a bacterial system can increase efficiency for plant transformations. Use of DSM-2 as the sole selection marker eliminates the need for an additional medicinal antibiotic marker (such as ampicillin resistance) during cloning. Various other uses are also possible according to the subject invention.Type: GrantFiled: December 7, 2007Date of Patent: August 25, 2020Assignee: Dow AgroSciences LLCInventors: Justin M. Lira, Terry R. Wright, Sean M. Russell, Donald J. Merlo, Steven R. Webb, Nicole L. Arnold, Andrew E. Robinson, Kelley A. Smith
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Publication number: 20200157555Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.Type: ApplicationFiled: October 1, 2019Publication date: May 21, 2020Inventors: Justin M. Lira, Robert Cicchillo, Carla N. Yerkes, Andrew E. Robinson
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Patent number: 10577618Abstract: The present disclosure relates to a novel class of EPSPS enzymes, and nucleic acids useful in encoding the same.Type: GrantFiled: May 11, 2016Date of Patent: March 3, 2020Assignee: Dow AgroSciences LLCInventors: Justin M. Lira, Robert M. Cicchillo, Satish K. Nair
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Patent number: 10577619Abstract: The present disclosure relates to certain polypeptides derived from prokaryotic DGT enzymes, and nucleic acids useful in encoding the same.Type: GrantFiled: June 30, 2016Date of Patent: March 3, 2020Assignee: Dow AgroSciences LLCInventors: Justin M. Lira, Robert Cicchillo, Carla N Yerkes, Andrew E Robinson
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Patent number: 10443070Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.Type: GrantFiled: January 26, 2018Date of Patent: October 15, 2019Assignee: Dow AgroSciences LLCInventors: Javier A. Delgado, Justin M. Lira, Chaoxian Geng, Tony K. Trullinger
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Patent number: 10428339Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.Type: GrantFiled: November 15, 2016Date of Patent: October 1, 2019Assignee: Dow AgroSciences LLCInventors: Justin M. Lira, Robert Cicchillo, Carla N. Yerkes, Andrew E. Robinson
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Patent number: 10421972Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.Type: GrantFiled: November 29, 2016Date of Patent: September 24, 2019Assignee: Dow AgroSciences LLCInventors: Justin M. Lira, Robert Cicchillo, Carla N. Yerkes, Andrew E. Robinson
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Patent number: 10392620Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.Type: GrantFiled: November 1, 2017Date of Patent: August 27, 2019Assignee: Dow AgroSciences LLCInventors: Javier A. Delgado, Justin M. Lira, Chaoxian Geng, Meghan L. Frey
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Publication number: 20190127754Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.Type: ApplicationFiled: October 3, 2018Publication date: May 2, 2019Applicant: Dow AgroSciences LLCInventors: Javier A. Delgado, Justin M. Lira, Michael T. Sullenberger, Robert Cicchillo
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Patent number: 10253323Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.Type: GrantFiled: August 17, 2016Date of Patent: April 9, 2019Assignee: Dow AgroSciences LLCInventors: Justin M. Lira, Robert Cicchillo, Carla N. Yerkes, Andrew E. Robinson
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Patent number: 10167483Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.Type: GrantFiled: September 19, 2014Date of Patent: January 1, 2019Assignee: Dow AgroSciences LLCInventors: Terry R. Wright, Justin M. Lira, Terence Anthony Walsh, Donald Merlo, Jayakumar Pon Samuel, Gaofeng Lin
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Publication number: 20180320179Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.Type: ApplicationFiled: April 5, 2018Publication date: November 8, 2018Applicant: Dow AgroSciences LLCInventors: Javier A. Delgado, Justin M. Lira, Chaoxian Geng, Meghan L. Frey
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Publication number: 20180216130Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.Type: ApplicationFiled: January 26, 2018Publication date: August 2, 2018Applicant: Dow AgroSciences LLCInventors: Javier A. Delgado, Justin M. Lira, Chaoxian Geng, Tony K. Trullinger
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Patent number: 10028510Abstract: DIG-17 insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.Type: GrantFiled: August 20, 2015Date of Patent: July 24, 2018Assignee: Dow AgroSciences LLCInventors: Justin M. Lira, Holly Jean Butler, Timothy D. Hey, Doug A. Smith, Kenneth Narva, Aaron T. Woosley