Patents by Inventor Justin M. Lira

Justin M. Lira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220290175
    Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
    Type: Application
    Filed: May 23, 2022
    Publication date: September 15, 2022
    Inventors: Terry R. WRIGHT, Justin M. LIRA, Terence Anthony WALSH, Donald MERLO, Jayakumar Pon SAMUEL, Gaofeng LIN
  • Patent number: 11371055
    Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: June 28, 2022
    Assignee: Corteva Agriscience LLC
    Inventors: Terry R. Wright, Justin M. Lira, Terence Anthony Walsh, Donald Merlo, Jayakumar Pon Samuel, Gaofeng Lin
  • Patent number: 10913955
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: February 9, 2021
    Assignee: Dow AgroSciences LLC
    Inventors: Javier A. Delgado, Justin M. Lira, Michael T. Sullenberger, Robert Cicchillo
  • Patent number: 10876131
    Abstract: DIG-303 insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: December 29, 2020
    Assignee: DOW AGROSCIENCES LLC
    Inventors: Meghan L. F. Frey, Justin M. Lira, Xiaoping Xu, Ignacio Mario Larrinua, Kenneth Narva, Timothy D Hey
  • Publication number: 20200385751
    Abstract: The subject invention relates to a novel gene referred to herein as DSM-2. This gene was identified in Streptomyces coelicolor A3. The DSM-2 protein is distantly related to PAT and BAR. The subject invention also provides plant-optimized genes encoding DSM-2 proteins. DSM-2 can be used as a transgenic trait to impart tolerance in plants and plant cells to the herbicides glufosinate and bialaphos. One preferred use of the subject genes are as selectable markers. The use of this gene as a selectable marker in a bacterial system can increase efficiency for plant transformations. Use of DSM-2 as the sole selection marker eliminates the need for an additional medicinal antibiotic marker (such as ampicillin resistance) during cloning. Various other uses are also possible according to the subject invention.
    Type: Application
    Filed: August 20, 2020
    Publication date: December 10, 2020
    Applicant: Dow AgroSciences LLC
    Inventors: Justin M Lira, Terry Wright, Andrew E. Robinson, Sean Russell, Donald J Merlo, Steven Webb, Nicole L Arnold, Kelley E Smith
  • Publication number: 20200385752
    Abstract: The subject invention relates to a novel gene referred to herein as DSM-2. This gene was identified in Streptomyces coelicolor A3. The DSM-2 protein is distantly related to PAT and BAR. The subject invention also provides plant-optimized genes encoding DSM-2 proteins. DSM-2 can be used as a transgenic trait to impart tolerance in plants and plant cells to the herbicides glufosinate and bialaphos. One preferred use of the subject genes areas selectable markers. The use of this gene as a selectable marker in a bacterial system can increase efficiency for plant transformations. Use of DSM-2 as the sole selection marker eliminates the need for an additional medicinal antibiotic marker (such as ampicillin resistance) during cloning. Various other uses are also possible according to the subject invention.
    Type: Application
    Filed: August 20, 2020
    Publication date: December 10, 2020
    Applicant: Dow AgroSciences LLC
    Inventors: Justin M Lira, Terry Wright, Andrew E. Robinson, Sean Russell, Donald J Merlo, Steven Webb, Nicole L Arnold, Kelley E Smith
  • Patent number: 10752913
    Abstract: The subject invention relates to a novel gene referred to herein as DSM-2. This gene was identified in Sterptomyces coelicolor A3. The DSM-2 protein is distantly related to PAT and BAR. The subject invention also provides plant-optimized genes encoding DSM-2 proteins, DSM-2 can be used as a transgenic trait to impart tolerance in plants and plant cells to the herbicides glufosinate and bialaphos. One preferred use of the subject genes are as selectable markers. The use of this gene as a selectable marker in a bacterial system can increase efficiency for plant transformations. Use of DSM-2 as the sole selection marker eliminates the need for an additional medicinal antibiotic marker (such as ampicillin resistance) during cloning. Various other uses are also possible according to the subject invention.
    Type: Grant
    Filed: December 7, 2007
    Date of Patent: August 25, 2020
    Assignee: Dow AgroSciences LLC
    Inventors: Justin M. Lira, Terry R. Wright, Sean M. Russell, Donald J. Merlo, Steven R. Webb, Nicole L. Arnold, Andrew E. Robinson, Kelley A. Smith
  • Publication number: 20200157555
    Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.
    Type: Application
    Filed: October 1, 2019
    Publication date: May 21, 2020
    Inventors: Justin M. Lira, Robert Cicchillo, Carla N. Yerkes, Andrew E. Robinson
  • Patent number: 10577618
    Abstract: The present disclosure relates to a novel class of EPSPS enzymes, and nucleic acids useful in encoding the same.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: March 3, 2020
    Assignee: Dow AgroSciences LLC
    Inventors: Justin M. Lira, Robert M. Cicchillo, Satish K. Nair
  • Patent number: 10577619
    Abstract: The present disclosure relates to certain polypeptides derived from prokaryotic DGT enzymes, and nucleic acids useful in encoding the same.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: March 3, 2020
    Assignee: Dow AgroSciences LLC
    Inventors: Justin M. Lira, Robert Cicchillo, Carla N Yerkes, Andrew E Robinson
  • Patent number: 10443070
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: October 15, 2019
    Assignee: Dow AgroSciences LLC
    Inventors: Javier A. Delgado, Justin M. Lira, Chaoxian Geng, Tony K. Trullinger
  • Patent number: 10428339
    Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: October 1, 2019
    Assignee: Dow AgroSciences LLC
    Inventors: Justin M. Lira, Robert Cicchillo, Carla N. Yerkes, Andrew E. Robinson
  • Patent number: 10421972
    Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: September 24, 2019
    Assignee: Dow AgroSciences LLC
    Inventors: Justin M. Lira, Robert Cicchillo, Carla N. Yerkes, Andrew E. Robinson
  • Patent number: 10392620
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: August 27, 2019
    Assignee: Dow AgroSciences LLC
    Inventors: Javier A. Delgado, Justin M. Lira, Chaoxian Geng, Meghan L. Frey
  • Publication number: 20190127754
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.
    Type: Application
    Filed: October 3, 2018
    Publication date: May 2, 2019
    Applicant: Dow AgroSciences LLC
    Inventors: Javier A. Delgado, Justin M. Lira, Michael T. Sullenberger, Robert Cicchillo
  • Patent number: 10253323
    Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: April 9, 2019
    Assignee: Dow AgroSciences LLC
    Inventors: Justin M. Lira, Robert Cicchillo, Carla N. Yerkes, Andrew E. Robinson
  • Patent number: 10167483
    Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: January 1, 2019
    Assignee: Dow AgroSciences LLC
    Inventors: Terry R. Wright, Justin M. Lira, Terence Anthony Walsh, Donald Merlo, Jayakumar Pon Samuel, Gaofeng Lin
  • Publication number: 20180320179
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.
    Type: Application
    Filed: April 5, 2018
    Publication date: November 8, 2018
    Applicant: Dow AgroSciences LLC
    Inventors: Javier A. Delgado, Justin M. Lira, Chaoxian Geng, Meghan L. Frey
  • Publication number: 20180216130
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.
    Type: Application
    Filed: January 26, 2018
    Publication date: August 2, 2018
    Applicant: Dow AgroSciences LLC
    Inventors: Javier A. Delgado, Justin M. Lira, Chaoxian Geng, Tony K. Trullinger
  • Patent number: 10028510
    Abstract: DIG-17 insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: July 24, 2018
    Assignee: Dow AgroSciences LLC
    Inventors: Justin M. Lira, Holly Jean Butler, Timothy D. Hey, Doug A. Smith, Kenneth Narva, Aaron T. Woosley