Abstract: Systems and methods are provided for evaluation of networks and changes thereto using automated analysis of network models. The automated analysis can be used to determine how to implement and mutate networks efficiently and effectively, to determine whether and why network resources are unable to communicate with each other, and the like. Automated analysis can allow users (e.g., network administrators) to define networks and pose changes to networks using high-level policies (e.g., written in a declarative language), have those polices automatically translated to lower-level implementation operations for analysis, and in some cases have results of the analysis presented back to the users in an easy-to-understand form.

Abstract: Disclosed herein are self-assembling protein nanoparticles comprising passenger molecules of interest.

Abstract: A drying appliance includes a cabinet with a processing chamber operably disposed therein. A blower delivers process air through an airflow path. The airflow path includes the processing chamber. A condensing airflow path has an inlet positioned within a front panel of the cabinet and an outlet positioned within a bottom panel of the cabinet. A condensing blower moves condensing air from the inlet to the outlet. An airflow seal extends downward from a front edge of the cabinet. The airflow seal separates a low-pressure region proximate the inlet from a high-pressure region proximate the outlet to block convection between the outlet and the inlet.

Abstract: A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Abstract: A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Abstract: The present invention relates to microfluidic fluidic systems and methods for the in vitro modeling diseases of the lung and small airway. In one embodiment, the invention relates to a system for testing responses of a microfluidic Small Airway-on-Chip infected with one or more infectious agents (e.g. respiratory viruses) as a model of respiratory disease exacerbation (e.g. asthma exacerbation). In one embodiment, this disease model on a microfluidic chip allows for a) the testing of anti-inflammatory and/or anti-viral compounds introduced into the system, as well as b) the monitoring of the participation, recruitment and/or movement of immune cells, including the transmigration of cells. In particular, this system provides, in one embodiment, an in-vitro platform for modeling severe asthma as “Severe Asthma-on-Chip.” In some embodiments, this invention provides a model of viral-induced asthma in humans for use in identifying potentially effective treatments.

Abstract: A drying appliance includes a cabinet. A drum processes articles of laundry. The drum is positioned for rotational operation within the cabinet. A blower directs process air through a recirculating airflow path that includes the drum. The drum and the blower are activated in an operating state and deactivated in an idle state. A first operable vent is positioned proximate a front of the cabinet. A second operable vent is positioned proximate a rear of the cabinet. The first and second operable vents define an open position after the drum and the blower define the idle state. The first and second operable vents define a closed position after the drum and the blower define the operating state.

Abstract: A docking station for an autonomous floor cleaner performs maintenance on the autonomous floor cleaner, including removing a mopping implement from the autonomous floor cleaner and/or installing a mopping implement on the autonomous floor cleaner. The docking station can further perform other maintenance services on the autonomous floor cleaner. An autonomous floor cleaning system including an autonomous floor cleaner and a docking station is also disclosed. Methods for servicing or performing maintenance on an autonomous floor cleaner by a docking station are also disclosed.

Abstract: A process for making a dry food is described herein. The process includes providing raw materials for a dry food to a preconditioning vessel at a first flowrate, preconditioning the raw materials in the preconditioning vessel and forming a dough, and moving the dough having a moisture content of from about 4% to about 10% through an inlet of an extruder. The process further includes extruding the dough through a die plate of the extruder and forming kibbles by: applying thermal energy to the dough; and applying mechanical energy to the dough, wherein the ratio of the thermal energy to the mechanical energy can range from at least about 2.0 to about 4.0.

Abstract: A laundry appliance includes a cabinet that has a user interface. A drum is disposed within the cabinet and includes baffles. A blower directs process air through an airflow path that includes the drum. A lint filter is disposed within the airflow path and between the drum and the blower. A foreign particulate collector is disposed within the drum and is configured to collect foreign particulates within the drum. A controller is operably coupled to a motor for rotating the drum and the blower. The user interface and the controller cooperate to operate the drum and the blower for capturing foreign particulates at least within the foreign particulate collector.

Abstract: The present disclosure generally relates to the field of digital currency, more particularly, cryptocurrency and secure payment systems using Public-key cryptography. The new cryptocurrency system utilizes digitally locked coins that can be owned and exchanged anonymously without the need for any owner account. Coin owners exchange coins by sending the digital keys of the coins, and recipients use the received digital keys to change the digital locks of the received coins. The digitally locked coins are tracked in a public book that is maintained centrally or distributively by one or more bookkeepers. The new cryptocurrency system is efficient and provides fast, anonymous, and secure transactions.

Abstract: The present invention relates to microfluidic fluidic systems and methods for the in vitro modeling diseases of the lung and small airway. In one embodiment, the invention relates to a system for testing responses of a microfluidic Small Airway-on-Chip infected with one or more infectious agents (e.g. respiratory viruses) as a model of respiratory disease exacerbation (e.g. asthma exacerbation). In one embodiment, this disease model on a microfluidic chip allows for a) the testing of anti-inflammatory and/or anti-viral compounds introduced into the system, as well as b) the monitoring of the participation, recruitment and/or movement of immune cells, including the transmigration of cells. In particular, this system provides, in one embodiment, an in-vitro platform for modeling severe asthma as “Severe Asthma-on-Chip.” In some embodiments, this invention provides a model of viral-induced asthma in humans for use in identifying potentially effective treatments.

Abstract: A laundry appliance includes an outer cabinet having opposing sidewalls that extend between a front panel and a rear panel. A blower is positioned within the outer cabinet and delivers process air through an airflow path. A rotating drum receives articles to be processed. The airflow path includes the rotating drum. A lint filter is selectively operable to a filtering position within a filter receptacle of the airflow path. The filtering position places a filter media of the lint filter within the airflow path. An access door is operable to a closed position within a door receptacle defined within a side panel of the opposing sidewalls. The door receptacle is aligned with the filter receptacle and the access door conceals the filter receptacle in the filtering position.

Abstract: A drying appliance includes a cabinet. A drum processes articles of laundry. The drum is positioned for rotational operation within the cabinet. A blower directs process air through a recirculating airflow path that includes the drum. The drum and the blower are activated in an operating state and deactivated in an idle state. A first operable vent is positioned proximate a front of the cabinet. A second operable vent is positioned proximate a rear of the cabinet. The first and second operable vents define an open position after the drum and the blower define the idle state. The first and second operable vents define a closed position after the drum and the blower define the operating state.

Abstract: A drying appliance includes a cabinet with a processing chamber operably disposed therein. A blower delivers process air through an airflow path. The airflow path includes the processing chamber. A condensing airflow path has an inlet positioned within a front panel of the cabinet and an outlet positioned within a bottom panel of the cabinet. A condensing blower moves condensing air from the inlet to the outlet. An airflow seal extends downward from a front edge of the cabinet. The airflow seal separates a low-pressure region proximate the inlet from a high-pressure region proximate the outlet to block convection between the outlet and the inlet.

Abstract: A drying appliance includes a cabinet. A drum processes articles of laundry. The drum is positioned for rotational operation within the cabinet. A blower directs process air through a recirculating airflow path that includes the drum. The drum and the blower are activated in an operating state and deactivated in an idle state. A first operable vent is positioned proximate a front of the cabinet. A second operable vent is positioned proximate a rear of the cabinet. The first and second operable vents define an open position after the drum and the blower define the idle state. The first and second operable vents define a closed position after the drum and the blower define the operating state.

Abstract: The present invention relates to devices including microfluidic devices, e.g. Skin on-Chip (Skin-Chip), for simulating a physiological response to agents and injury, including tattoo injury. In particular, a Skin-Chip is intended for use in replicating the interaction of tattoo ink with skin on a cellular level, including but not limited to mechanisms of wound healing following a tattoo gun and/or tattoo needle induced skin injury; ink particle effects such as pigment retention, pigment distribution and pigment clearance; inflammatory response to foreign particles, i.e. tattoo ink, etc. Further, effects of tattoo inks on simulated microfluidic skin is extended to determine effects of systemic ink exposure upon other organs through use of organ chips, e.g. liver-chips, kidney-chips, Lymph node-chips, etc. In some embodiments, safer ink formulations, e.g. less toxic ink particles, less toxic ink diluents, etc., are contemplated for development and use over currently available tattoo inks and diluents.

Abstract: A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Abstract: A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Abstract: Compositions, devices and methods are described for preventing, reducing, controlling or delaying adhesion, adsorption, surface-mediated clot formation, or coagulation in a microfluidic device or chip. In one embodiment, blood (or other fluid with blood components) that contains anticoagulant is introduced into a microfluidic device comprising one or more additive channels containing one or more reagents that will re-activate the native coagulation cascade in the blood that makes contact with it “on-chip” before moving into the experimental region of the chip.