Abstract: A laundry appliance includes an outer cabinet having opposing sidewalls that extend between a front panel and a rear panel. A blower is positioned within the outer cabinet and delivers process air through an airflow path. A rotating drum receives articles to be processed. The airflow path includes the rotating drum. A lint filter is selectively operable to a filtering position within a filter receptacle of the airflow path. The filtering position places a filter media of the lint filter within the airflow path. An access door is operable to a closed position within a door receptacle defined within a side panel of the opposing sidewalls. The door receptacle is aligned with the filter receptacle and the access door conceals the filter receptacle in the filtering position.

Abstract: A drying appliance includes a cabinet. A drum processes articles of laundry. The drum is positioned for rotational operation within the cabinet. A blower directs process air through a recirculating airflow path that includes the drum. The drum and the blower are activated in an operating state and deactivated in an idle state. A first operable vent is positioned proximate a front of the cabinet. A second operable vent is positioned proximate a rear of the cabinet. The first and second operable vents define an open position after the drum and the blower define the idle state. The first and second operable vents define a closed position after the drum and the blower define the operating state.

Abstract: A drying appliance includes a cabinet with a processing chamber operably disposed therein. A blower delivers process air through an airflow path. The airflow path includes the processing chamber. A condensing airflow path has an inlet positioned within a front panel of the cabinet and an outlet positioned within a bottom panel of the cabinet. A condensing blower moves condensing air from the inlet to the outlet. An airflow seal extends downward from a front edge of the cabinet. The airflow seal separates a low-pressure region proximate the inlet from a high-pressure region proximate the outlet to block convection between the outlet and the inlet.

Abstract: A drying appliance includes a cabinet. A drum processes articles of laundry. The drum is positioned for rotational operation within the cabinet. A blower directs process air through a recirculating airflow path that includes the drum. The drum and the blower are activated in an operating state and deactivated in an idle state. A first operable vent is positioned proximate a front of the cabinet. A second operable vent is positioned proximate a rear of the cabinet. The first and second operable vents define an open position after the drum and the blower define the idle state. The first and second operable vents define a closed position after the drum and the blower define the operating state.

Abstract: The present invention relates to devices including microfluidic devices, e.g. Skin on-Chip (Skin-Chip), for simulating a physiological response to agents and injury, including tattoo injury. In particular, a Skin-Chip is intended for use in replicating the interaction of tattoo ink with skin on a cellular level, including but not limited to mechanisms of wound healing following a tattoo gun and/or tattoo needle induced skin injury; ink particle effects such as pigment retention, pigment distribution and pigment clearance; inflammatory response to foreign particles, i.e. tattoo ink, etc. Further, effects of tattoo inks on simulated microfluidic skin is extended to determine effects of systemic ink exposure upon other organs through use of organ chips, e.g. liver-chips, kidney-chips, Lymph node-chips, etc. In some embodiments, safer ink formulations, e.g. less toxic ink particles, less toxic ink diluents, etc., are contemplated for development and use over currently available tattoo inks and diluents.

Abstract: A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Abstract: A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Abstract: Compositions, devices and methods are described for preventing, reducing, controlling or delaying adhesion, adsorption, surface-mediated clot formation, or coagulation in a microfluidic device or chip. In one embodiment, blood (or other fluid with blood components) that contains anticoagulant is introduced into a microfluidic device comprising one or more additive channels containing one or more reagents that will re-activate the native coagulation cascade in the blood that makes contact with it “on-chip” before moving into the experimental region of the chip.

Abstract: A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Abstract: Compositions, devices and methods are described for preventing, reducing, controlling or delaying adhesion, adsorption, surface-mediated clot formation, or coagulation in a microfluidic device or chip. In one embodiment, blood (or other fluid with blood components) that contains anticoagulant is introduced into a microfluidic device comprising one or more additive channels containing one or more reagents that will re-activate the native coagulation cascade in the blood that makes contact with it “on-chip” before moving into the experimental region of the chip.

Abstract: The present invention provides a longer-lasting edible animal chew (1) having a longitudinal axis comprising: i) an outer wall (2) extending in the direction of said longitudinal axis; and ii) an internal support structure (4) that contacts the inner surface of said outer wall (2) at three or more points.

Abstract: A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Abstract: An in vitro microfluidic “organ-on-chip” device is described herein that mimics the structure and at least one function of specific areas of the epithelial system in vivo. In particular, a stem cell-based Lung-on-Chip is described. This in vitro microfluidic system can be used for modeling differentiation of cells on-chip into lung cells, e.g., a lung (Lung-On-Chip), bronchial (Airway-On-Chip; small-Airway-On-Chip), alveolar sac (Alveolar-On-Chip), etc., for use in modeling disease states of derived tissue, i.e. as healthy, pre-disease and diseased tissues. Additionally, stem cells under differentiation protocols for deriving (producing) differentiated lung cells off-chips may be seeded onto microfluidic devices at any desired point during the in vitro differentiation pathway for further differentiation on-chip or placed on-chip before, during or after terminal differentiation.

Abstract: Compositions, devices and methods are described for preventing, reducing, controlling or delaying adhesion, adsorption, surface-mediated clot formation, or coagulation in a microfluidic device or chip. In one embodiment, blood (or other fluid with blood components) that contains anticoagulant is introduced into a microfluidic device comprising one or more additive channels containing one or more reagents that will re-activate the native coagulation cascade in the blood that makes contact with it “on-chip” before moving into the experimental region of the chip.

Abstract: Compositions, devices and methods are described for preventing, reducing, controlling or delaying adhesion, adsorption, surface-mediated clot formation, or coagulation in a microfluidic device or chip. In one embodiment, blood (or other fluid with blood components) that contains anticoagulant is introduced into a microfluidic device comprising one or more additive channels containing one or more reagents that will re-activate the native coagulation cascade in the blood that makes contact with it “on-chip” before moving into the experimental region of the chip.

Abstract: An edible pet chew is disclosed that has a twisted body form with enhanced textural characteristics over un-twisted body forms. The pet chew is comprised of fibrous protein, water absorbing polymer, plasticizer, water, and additives. The pet chew provides enhanced textural and oral hygiene properties.

Abstract: The present invention relates to microfluidic fluidic systems and methods for the in vitro modeling diseases of the lung and small airway. In one embodiment, the invention relates to a system for testing responses of a microfluidic Small Airway-on-Chip infected with one or more infectious agents (e.g. respiratory viruses) as a model of respiratory disease exacerbation (e.g. asthma exacerbation). In one embodiment, this disease model on a microfluidic chip allows for a) the testing of anti-inflammatory and/or anti-viral compounds introduced into the system, as well as b) the monitoring of the participation, recruitment and/or movement of immune cells, including the transmigration of cells. In particular, this system provides, in one embodiment, an in-vitro platform for modeling severe asthma as “Severe Asthma-on-Chip.” In some embodiments, this invention provides a model of viral-induced asthma in humans for use in identifying potentially effective treatments.

Abstract: Compositions, devices and methods are described for preventing, reducing, controlling or delaying adhesion, adsorption, surface-mediated clot formation, or coagulation in a microfluidic device or chip. In one embodiment, blood (or other fluid with blood components) that contains anticoagulant is introduced into a microfluidic device comprising one or more additive channels containing one or more reagents that will re-activate the native coagulation cascade in the blood that makes contact with it “on-chip” before moving into the experimental region of the chip.

Abstract: A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Abstract: In order to reduce service procedure time and labor costs, while increasing overall uptime, the electrical equipment cabinet of the invention includes a main service door that is integrated with the dead front. The dead front panel is fixed to and movable with the main service door, and therefore access to high voltage equipment situated behind the dead front is achieved by simply opening the main service door, without the need to first unlock and open the main service door and then unlock, open, and/or remove the dead front panel. Controls on the front side of the dead front are easily and safely accessible, when the main service door is closed, through a dead front control access door positioned within an opening of the main service door.