Abstract: The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopathy are provided. For example, the present invention provides materials and methods for modulating glymphatic clearance (e.g., enhancing glymphatic clearance) of pathogenic proteins.

Abstract: A cleaning device enables cleaning of a lens of an endoscope during a surgical procedure to maintain a clear image without having to remove the endoscope from the patient's body. The cleaning device is mountable to an endoscope such that a wiper of the cleaning device is selectively displaced across the lens of the endoscope to remove debris from the lens.

Abstract: An electronic chess set includes a plurality of conductive chess pieces, a chessboard having a playing surface including a plurality of individually identifiable locations visible to a user on the chessboard, and an electronic system including a capacitive sensing system. In some embodiments, the capacitive sensing system is configured to determine for each of the plurality of individually identifiable locations: when a chess piece included in the plurality of conductive chess pieces is located at a respective one of the plurality of individually identifiable locations and user-contact with the chess piece is absent; when the chess piece located at the respective one of the plurality of individually identifiable locations is in contact with the user; and when each of the plurality of conductive chess pieces is absent from the respective one of the plurality of individually identifiable locations.

Abstract: A medication vial lock comprising a first arm having a body, an upper surface, a lower surface, and a slot located on one side of the first arm, a second arm pivotally engaged with the first arm, the second arm having a body, an upper surface, a lower surface, and a slot located on one side of the second arm, wherein the slot located on the first arm and the slot located on the second arm are designed to encircle a medicine vial, a first aperture on the first arm extending through the body from the upper surface to the lower surface, a first lock aperture on the first arm extending through the body from the upper surface to the lower surface, and a second lock aperture on the second arm extending through the body from the upper surface to the lower surface.

Abstract: The present disclosure relates to adapter assemblies for use with and to electrically and mechanically interconnect electromechanical surgical devices and surgical reloads, and to surgical systems including handheld electromechanical surgical devices and adapter assemblies for connecting surgical reloads to the handheld electromechanical surgical devices.

Abstract: Surgical instruments include a first drive assembly having a first drive gear and a lockout mechanism positioned for releasable engagement with the first drive assembly to inhibit rotation of the first drive gear. The lockout mechanism includes a pawl and an actuator means for moving the pawl from a first position in engagement with the first drive gear to a second position spaced from the first drive gear.

Abstract: A surgical stapling system includes a surgical stapling apparatus and a buttress loading unit. The surgical stapling apparatus includes a first jaw member and a second jaw member configured to fasten tissue grasped between the first and second jaw members. The buttress loading unit includes a loader and a clip supported in the loader. The loader and the clip support a release strap and a buttress. The clip is configured to selectively attach the release strap and the buttress to the first jaw member when the loader is positioned on the first jaw member.

Abstract: An electronic chess set includes a plurality of conductive chess pieces, a chessboard having a playing surface including a plurality of individually identifiable locations visible to a user on the chessboard, and an electronic system including a capacitive sensing system. In some embodiments, the capacitive sensing system is configured to determine for each of the plurality of individually identifiable locations: when a chess piece included in the plurality of conductive chess pieces is located at a respective one of the plurality of individually identifiable locations and user-contact with the chess piece is absent; when the chess piece located at the respective one of the plurality of individually identifiable locations is in contact with the user; and when each of the plurality of conductive chess pieces is absent from the respective one of the plurality of individually identifiable locations.

Abstract: Responsive to the request for a security fabric report, an upper-level node transits a request to a lower-level node for a subtree security report. If there are additional network gateways at lower hierarchical levels, the next level down repeats the process. A root level network gateway will transmit the first request, as the high level of the hierarchy, and a last leaf receives the last request, as the lowest level. An overall security fabric report is returned from the root node.

Abstract: A circular stapling device includes a handle assembly, an elongate body portion that extends distally from the handle assembly, a shell assembly supported on a distal end of the elongate body portion, an anvil retainer assembly extending through the shell assembly, and an anvil assembly supported on the anvil retainer assembly. The anvil retainer assembly includes a retainer member including a retainer body and an engagement member that is pivotally supported on the retainer body. The engagement member is movable axially in relation to the retainer body from a retracted position to an advanced position to move the engagement member to from a locked position to an unlocked position in relation to the retainer body. In the unlocked position, the engagement member is movable from a non-articulated position to an articulated position in relation to the retainer body.

Abstract: A surgical stapling device includes an adapter assembly and a reload assembly. The adapter assembly includes an elongate body and a channel member coupled to the elongate body. The reload assembly includes an anvil and a cartridge assembly that includes a cartridge body and a channel extension. A proximal portion of the cartridge body is received within the channel member to secure the reload assembly to the adapter assembly. The channel extension is received about a distal portion of the cartridge body and is engaged with the channel member to support the cartridge body.

Abstract: Densified textile aggregates are co-fed with a fuel into a partial oxidation gasifier. High solids concentrations in the feedstock composition can be obtained without significant impact on the feedstock composition stability and pumpability. A consistent quality of densified textile derived syngas can be continuously produced, including generation of carbon dioxide and a carbon monoxide/hydrogen ratio while stably operating the gasifier and avoiding the high tar generation of fluidized bed or fixed bed waste gasifiers and without impacting the operations of the gasifier. The densified textile derived syngas quality, composition, and throughput are suitable for produce a wide range of chemicals and polymers, including methanol, acetic acid, methyl acetate, acetic anhydride, and cellulose esters through a variety of reaction schemes in which at least a portion of the chemical or polymer originates with densified textile derived syngas.

Abstract: Pre-ground plastics of small particle size not more than 2 mm are co-fed into a solid fossil fuel fed entrained flow partial oxidation gasifier. High solids concentrations in the feedstock stream can be obtained without significant impact on the feedstock stream stability and pumpability. A consistent quality of syngas can be continuously produced, including generation of carbon dioxide and a carbon monoxide/hydrogen ratio while stably operating the gasifier and avoiding the high tar generation of fluidized bed or fixed bed waste gasifiers and without impacting the operations of the gasifier. The subsequent syngas produced from this material can be used to produce a wide range of chemicals.

Abstract: Pre-ground plastics of small particle size not more than 2 mm are co-fed into a solid fossil fuel fed entrained flow partial oxidation gasifier. High solids concentrations in the feedstock stream can be obtained without significant impact on the feedstock stream stability and pumpability. A consistent quality of syngas can be continuously produced, including generation of carbon dioxide and a carbon monoxide/hydrogen ratio while stably operating the gasifier and avoiding the high tar generation of fluidized bed or fixed bed waste gasifiers and without impacting the operations of the gasifier. The subsequent syngas produced from this material can be used to produce a wide range of chemicals.

Abstract: A surgical stapling system includes a surgical stapling apparatus and a staple cartridge surgical buttress assembly. The surgical stapling apparatus includes a handle assembly, an elongate tubular body extending distally from the handle assembly, and an end effector extending distally from the elongate tubular body. The end effector includes an anvil assembly and a staple cartridge assembly. The staple cartridge surgical buttress assembly includes a surgical buttress and a leash. The surgical buttress includes a body having an annular configuration and legs extending from the body. The body is positioned against a tissue facing surface of the staple cartridge assembly and the legs are positioned against a housing of the staple cartridge assembly. The leash is threaded through at least one of the legs and extends proximally from the surgical buttress towards the handle assembly.

Abstract: The representative embodiments discussed in the present disclosure relate to techniques with which data packet loss, such as Transmission Control Protocol (TCP) packet loss, may be detected. More specifically, in some embodiments, by detecting a TCP packet with an enabled selective acknowledgement (SACK) signal, the loss (e.g., drop) of an additional TCP packet may be determined. Moreover, using information included in the detected TCP packet, an operational efficiency of a cloud computing system and/or a component of the cloud computing system may be determined.

Abstract: An electronic chess set includes a plurality of conductive chess pieces, a chessboard having a playing surface including a plurality of individually identifiable locations visible to a user on the chessboard, and an electronic system including a capacitive sensing system. In some embodiments, the capacitive sensing system is configured to determine for each of the plurality of individually identifiable locations: when a chess piece included in the plurality of conductive chess pieces is located at a respective one of the plurality of individually identifiable locations and user-contact with the chess piece is absent; when the chess piece located at the respective one of the plurality of individually identifiable locations is in contact with the user; and when each of the plurality of conductive chess pieces is absent from the respective one of the plurality of individually identifiable locations.

Abstract: An adapter assembly includes a base member, a housing, and a locking mechanism. The base member defines a longitudinal axis. The housing is rotatably secured to the base member and is rotatable in relation to the base member between a plurality of positions. The locking mechanism is supported on the housing and includes a locking member and a button. The locking member is moveable from a locked position in which a lock of the locking member is engaged with the base member to secure the housing in one of the plurality of positions to an unlocked position in which the housing is rotatable in relation to the base member. The button is positioned on the base member and is depressible to translate the locking member in a direction parallel to the longitudinal axis from the locked position to the unlocked position.

Abstract: A surgical grasper includes jaws that are transitionable between spaced apart and approximated configurations. In particular, the surgical grasper defines an unobstructed lumen for passage of a surgical instrument therethrough.