Patents by Inventor Juswinder Singh

Juswinder Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazolopyridines and methods of making and using the same
    Publication number: 20060106033
    Abstract: Compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders.
    Type: Application
    Filed: September 5, 2003
    Publication date: May 18, 2006
    Inventors: Wen-Cherng Lee, Mary Carter, Lihong Sun, Claudio Chuaqui, Zhongli Zheng, Juswinder Singh, Paula Boriack-Sjodin, Paul Lyne
  • Cell adhesion inhibitors
    Patent number: 6630512
    Abstract: The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of using them for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. The compounds and pharmaceutical compositions of this invention can be used as therapeutic or prophylactic agents. They are particularly well-suited for treatment of many inflammatory and autoimmune diseases.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: October 7, 2003
    Assignee: Biogen, Inc.
    Inventors: Steven P. Adams, Ko-Chung Lin, Wen-Cherng Lee, Alfredo C. Castro, Craig N. Zimmerman, Charles E. Hammond, Yu-Sheng Liao, Julio Hernan Cuervo, Juswinder Singh
  • Molecular model for VLA-4 inhibitors
    Patent number: 6552216
    Abstract: Pharmacophore models of VLA-4 inhibitors, methods of identifying novel inhibitors and novel inhibitors identified by these methods.
    Type: Grant
    Filed: January 25, 1999
    Date of Patent: April 22, 2003
    Assignee: Biogen, Inc.
    Inventors: Juswinder Singh, Zhongli Zheng, Peter Sprague, Herman Van Vlijmen, Alfredo Castro, Steven P. Adams
  • Cell adhesion inhibitors
    Publication number: 20030018016
    Abstract: The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of using them for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. The compounds and pharmaceutical compositions of this invention can be used as therapeutic or prophylactic agents. They are particularly well-suited for treatment of many inflammatory and autoimmune diseases.
    Type: Application
    Filed: October 23, 2001
    Publication date: January 23, 2003
    Inventors: Steven P. Adams, Ko-Chung Lin, Wen-Cherng Lee, Alfredo C. Castro, Craig N. Zimmerman, Charles E. Hammond, Yu-Sheng Liao, Julio Hernan Cuervo, Juswinder Singh
  • Cell adhesion inhibitors
    Patent number: 6376538
    Abstract: The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of using them for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. The compounds and pharmaceutical compositions of this invention can be used as therapeutic or prophylactic agents. They are particularly well-suited for treatment of many inflammatory and autoimmune diseases.
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: April 23, 2002
    Assignee: Biogen, Inc.
    Inventors: Steven P. Adams, Ko-Chung Lin, Wen-Cherng Lee, Alfredo C. Castro, Craig N. Zimmerman, Charles E. Hammond, Yu-Sheng Liao, Julio Hernan Cuervo, Juswinder Singh
  • Compounds, compositions and methods for inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins
    Patent number: 5922697
    Abstract: The present invention provides compounds that inhibit the binding of proteins containing an SH2 domain to cognate phosphorylated proteins. The invention also provides pharmaceutical compositions containing the compounds and methods of inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: July 13, 1999
    Assignee: Warner-Lambert Company
    Inventors: Elizabeth A. Lunney, Kimberly S. Para, Mark S. Plummer, Josyula V. N. V. Prasad, Alan R. Saltiel, Tomi Sawyer, Aurash Shahripour, Juswinder Singh, Charles J. Stankovic