Abstract: A tooth jump protection device is used to control chain slack and delay the torque at which chain jump occurs, thus increasing jump torque performance. The tooth jump protection device is preferably mounted to the transfer case.

Abstract: A pattern for application to the face of the tensioner arm, guide or snubber in contact with a chain to intentionally break up the chain contact force between the back of the chain links and the tensioner arm, guide or snubber face. This is done to prevent alignment with the chain related orders which are causing NVH within the chain system or to increase overall NVH to obscure chain related orders.

Abstract: A system is provided for simulating a cyberattack as a simulated cyberattack on a real industrial control facility that includes reals sensor devices. The system generates simulated sensor signals that are representative of sensor signals generated by a sensor of a real sensor device that is the target of the simulated cyberattack. The system injects the simulated sensor signals into the real sensor device so that the real sensor device generates an output based on the simulated sensor signals. The system monitors the response of a personnel of the industrial control facility. The system then generates an assessment of the response based on a target response. The system may rerun the simulated cyberattack based on the assessment.

Abstract: An incident simulation system supports an incident exercise in a virtual environment. The incident simulation system accesses a simulation plan defining an incident within a theater of operation. The incident simulation system simulates the incident exercise by displaying, to a participant in the incident exercise, images representing what the participant would see within the theater of operation as the participant moves within the theater of operation. The incident simulation system further simulates the incident by generating incident data indicating effects of the incident at target locations and at target times as the participant moves within the theater of operation. The incident simulation system further simulates the incident by displaying to the participant images representing the user experience that a detector would provide based on the generated incident data.

Abstract: The present disclosure provides methods, devices, systems and kits for producing polymeric microbeads, including lanthanide-encoded microbeads. Among others, the present disclosure provides methods, systems and kits for producing functionalized microbeads that include on their surfaces amphipathic moieties with free reactive groups that remain free and can be used for covalently coupling molecules or moieties of inters to the microbeads.

Abstract: An incident exercise system supports an incident exercise. The incident exercise system accesses an exercise plan defining an incident within a theater of operation. The incident exercise system administers the incident exercise by generating detector signals factoring in incident effects and characteristic effects of the theater of operation. The incident exercise system sends detector signals to detectors that filter effect of background noise from the detector signals to generate filtered detector signals and output data derived from the filtered detector signals. The incident exercise system supports dynamically modifying the exercise plan during the incident exercise.

Abstract: An incident exercise system supports an incident exercise. The incident exercise system accesses an exercise plan defining an incident within a theater of operation. The incident exercise system administers the incident exercise by generating detector signals factoring in incident effects and characteristic effects of the theater of operation. The incident exercise system sends detector signals to detectors that filter effect of background noise from the detector signals to generate filtered detector signals and output data derived from the filtered detector signals. The incident exercise system supports dynamically modifying the exercise plan during the incident exercise.

Abstract: A prosthetic heart includes a support structure, an actuator member, a plurality of leaflets, and a sealing material. The support structure includes a plurality of struts movably coupled together such that the support structure moves incrementally between a radially compressed state and a radially expanded state. The struts include a plurality of commissure struts. The actuator member is coupled to the struts of the support structure and is configured to incrementally move the support structure between the radially compressed state and the radially expanded state and to automatically lock the support structure in a particular state. The leaflets are coupled to the commissure struts of the support structure and configured to allow unidirectional blood flow through the prosthetic heart valve. The sealing material is coupled to the support structure and includes a plurality of commissure extensions that wrap around and are coupled to the commissure struts of the support structure.

Abstract: A chain guide and tensioning apparatus is disclosed that is configured for engagement (contact) with a driven chain (e.g., in an automotive engine). The chain guide and tensioning apparatus includes a guide body and a guide face overlying the guide body. The guide face defines an inner surface and an opposite outer surface that is configured to guide and tension the driven chain. The guide face includes a plurality of spacers that extend therefrom into engagement (contact) with the guide body so as to define at least one channel that is configured to facilitate air and/or lubricant circulation between the guide body and the guide face to reduce heat and friction generated by engagement of the driven chain with the guide face.

Abstract: The present disclosure provides novel bispecific molecules that binds to human Survivin and human CD3, and methods of making and using the same.

Abstract: The invention provides compositions and methods for associating data from phenotypic analysis of a single cell with sequencing data from the single cell using spectrally-encoded microbeads.

Abstract: A tooth jump protection device is used to control chain slack and delay the torque at which chain jump occurs, thus increasing jump torque performance. The tooth jump protection device is preferably mounted to the transfer case.

Abstract: A prosthetic heart valve can include a support structure, an actuator member, and a plurality of leaflets. The support structure can have a plurality of struts and a plurality of rivets. The struts can have openings formed therein. The rivets can have first portions and second portions. The first portions can extend through the openings of the struts, and the second portions are larger than the first portion and the openings of the struts. The struts are pivotable about the rivets to radially expand and compress the support structure. The actuator member can be coupled to the struts of the support structure and configured to selectively actuate expansion and compression of the support structure. The leaflets can be coupled to the support structure and configured to allow unidirectional blood flow through the prosthetic heart valve.

Abstract: Methods for characterizing a population of microbes in a sample are described. The methods include: amplifying microbial polynucleotides obtained from the sample to form a plurality of amplicons and combining the amplicons with a plurality of microbeads, wherein each of the microbeads has a lanthanide spectral signature paired with the sequence of capture polynucleotides immobilized on the microbead. At least some of the capture polynucleotides comprise a sequence substantially complementary to a microbe-identifying sequence in one or more amplicons, such that at least some amplicons are captured onto beads by the capture polynucleotides and the microbe can be identified based on the lanthanide spectral signature of with which the capture polynucleotide is paired. Further described are methods for the identification of pathogens present in a sample by evaluating patterns of hybridization of a capture oligonucleotide to amplicons.

Abstract: De-icing processes and products with coatings enabling de-icing are disclosed. The de-icing process includes mechanically removing ice from a coated article having a chemical vapor deposition coating. The chemical vapor deposition coating includes silicon, carbon, and fluorine. The chemical vapor deposition coating is hydrophobic and oleophobic. The chemical vapor deposition coating remains hydrophobic and oleophobic after the mechanically removing of the ice. The product is a coated article having a chemical vapor deposition coating and ice on the chemical vapor deposition coating. The chemical vapor deposition coating includes silicon, carbon, and fluorine. The chemical vapor deposition coating is hydrophobic and oleophobic. The chemical vapor deposition coating remains hydrophobic and oleophobic in response to mechanically removing of the ice on the chemical vapor deposition coating.

Abstract: A technique for non-invasively assessing current drawn by a device under test (DUT) by monitoring a supply voltage to the DUT. Frequency data for the DUT may be generated and used to form a current estimation model. First and second voltages are simultaneously measured using first and second test probes electrically connected to the DUT, while the first test probe is connected at a current source, and while the second test probe is connected at a DUT load that is configured to draw current from the current source. The current drawn by the DUT is then assessed by applying the current estimation model to the measured first and second voltages. In one case, the current drawn by the DUT is estimated without insertion of a circuit component into the DUT or extraction of a circuit conductor from the DUT.

Abstract: An incident simulation system supports an incident exercise in a virtual environment. The incident simulation system accesses a simulation plan defining an incident within a theater of operation. The incident simulation system simulates the incident exercise by displaying, to a participant in the incident exercise, images representing what the participant would see within the theater of operation as the participant moves within the theater of operation. The incident simulation system further simulates the incident by generating incident data indicating effects of the incident at target locations and at target times as the participant moves within the theater of operation. The incident simulation system further simulates the incident by displaying to the participant images representing the user experience that a detector would provide based on the generated incident data.

Abstract: A frame for a prosthetic valve includes pivoting struts and outer bow struts. A first end of each pivoting strut is pivotably coupled to a first pivoting strut, a second end of each pivoting strut is pivotably coupled to a second pivoting strut, and an intermediate portion of each pivoting strut, which is disposed between the first end and the second end, is pivotably coupled to a third pivoting strut. The outer bow struts are disposed outwardly from the pivoting struts. An inflow end of each outer bow strut is connected to the first end of a respective pivoting strut, and an outflow end of each outer bow strut is connected to the second end of a respective pivoting strut. The outer bow struts deflect outwardly relative to the intermediate portions of the pivoting struts when the frame is moved from a radially compressed configuration to a radially expanded configuration.

Abstract: A storage and transport system for sodium hypochlorite pentahydrate (solid bleach) is provided. The system includes a container configured to receive and store crystalline solid bleach that includes of at least forty percent sodium hypochlorite, and to retain decomposition components from crystalline solid bleach stored in the container. The container includes a containment wall at least partially surrounding an interior containment space configured to receive solid bleach therein. A passage extends from exterior the container to the interior containment space. The passage is configured for solid bleach to pass therethrough. A liner is located at an interior surface of the containment wall. The liner is substantially non-reactive with solid bleach and, without leakage, capable of retaining within the containment space: (a) solid bleach, (b) decomposition components of solid bleach and (c) liquid bleach formed when dissolving water is added to solid bleach within the containment space.

Abstract: Described herein are solid state 17?-ethynylandrost-5-ene-3?,7?,17?-triol including amorphous and crystalline forms and specific polymorphic forms thereof, and use of solid state 17?-ethynylandrost-5-ene-3?,7?,17?-triol in treating numerous diseases and disorders, including hyperglycemic conditions, such as type 2 diabetes and metabolic syndrome, autoimmune conditions, such as rheumatoid arthritis, ulcerative colitis and type 1 diabetes, among other inflammation related conditions, and neurodegenerative conditions in subjects or human patients.