Abstract: A phototherapy system includes a channel driver, a first microcontroller and a pad comprising a string of light-emitting diodes (LEDs). The pad also comprises a second microcontroller that autonomously controls the string of LEDs such that the LEDs are controlled even if communication between the first microcontroller and the pad is interrupted.

Abstract: A method is disclosed of retrofitting an elevator machine with primary and secondary braking, the machine being disposed on a machine support frame in an elevator machine room, and engaging one or more ropes for providing selective movement of an elevator car disposed in an elevator shaft, the machine having a drive sheave including a cylindrical brake drum, and brake components including dual brake arms; the method including: removing the brake components; affixing flanged disc segments about the drum and interlocking the flanged disc segments to form a brake rotor; and mounting respective brake calipers to frame mounts for providing primary and secondary braking to the elevator machine.

Abstract: An expandable cage system for use in spinal surgery includes a top portion having an outwardly extending top arm, and a bottom portion having an outwardly extending bottom arm. The bottom arm is configured to engage with the top arm such that upon engagement, the top portion and the bottom portion are substantially restricted from movement relative to each other in an anterior-posterior direction, and in a medial-lateral direction. The expandable cage system further includes a removable shim configured to be positioned between the top portion and the bottom portion to hold the expandable cage in an expanded position within a spinal cavity.

Abstract: A phototherapy system includes a channel driver, a first microcontroller and a pad comprising a string of light-emitting diodes (LEDs). The pad also comprises a second microcontroller that autonomously controls the string of LEDs such that the LEDs are controlled even if communication between the first microcontroller and the pad is interrupted.

Abstract: The present invention provides compounds of Formula (I): (I) wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).

Abstract: A portable negative air pressure apparatus for isolating a treatment subject to permit a selected treatment procedure to be performed by a treatment operator. The apparatus comprises an air source connected to a closed chamber for sealable disposition over the head, neck and upper thorax of the treatment subject with the chamber having air ports, in and out. The chamber has rigid clear sides and a plurality of sealed ports, with the ports including sealed armholes for access, and with sealed gloves connected to the sealed armholes. The chamber also has at least one instrument hatch to permit introduction into the chamber of instruments for carrying-out the selected treatment procedure.

Abstract: Disclosed is a method for retrofitting an elevator machine with a thrust bearing, including removing, from a bearing stand, a first cover plate, providing access to an end portion of a motor shaft, securing an extension shaft against the end portion of the motor shaft, securing a thrust bearing housing against or axially offset from the bearing stand, positioning a thrust bearing in the bearing housing, wherein an inner race of the thrust bearing is securely positioned against, and axially fixed to, the extension shaft, and an outer race of the thrust bearing is securely positioned against the bearing housing, and securing a second cover plate to the bearing housing.

Abstract: A system is presented for load balancing across media server instances. In an embodiment, media is broken out into a multi-tenanted service allowing the media to be scaled independently of the number of organizations supported on a cloud-based collaboration platform. Scaling may occur in a scaling-out or a scaling-in operation. States for a media service may comprise in-service, quiescing, quiesced, failed, etc. The states may be used to monitor sessions associated with an instance and determine which media instances to terminate during a scaling-in operation. In an embodiment, new instances may be added to a collection of media instances in response to an increased workload in a scaling-out operation.

Abstract: The present disclosure provides compositions and methods for treatment of a kidney disease with chemokine protein stromal cell-derived factor 1 (SDF-1), such as methods of treating a subject afflicted with or at risk of developing a kidney disease, comprising administering SDF-1 to a kidney of the subject in a treatment-effective amount.

Abstract: The present invention provides compounds of Formula (I):(I) wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).

Abstract: An expandable cage system for use in spinal surgery includes a top portion having an outwardly extending top arm, and a bottom portion having an outwardly extending bottom arm. The bottom arm is configured to engage with the top arm such that upon engagement, the top portion and the bottom portion are substantially restricted from movement relative to each other in an anterior-posterior direction, and in a medial-lateral direction. The expandable cage system further includes a removable shim configured to be positioned between the top portion and the bottom portion to hold the expandable cage in an expanded position within a spinal cavity.

Abstract: Software installed in the nodes in a communication network allows them to perform a “name server” function, which entails the management of a dynamic list of the client devices that are connected to the cloud, a “task” function, which entails the receipt and transmission of the packets, and an “authority” function, which entails the determination of the routes of the packets through the cloud. Each node is capable of performing only one function at a time. After completing a job, a node reverts to an undifferentiated, state awaiting its next performance request.

Abstract: A fluid moving apparatus includes an electric motor having a rotor and a stator and a fluid displacement member. The rotor rotates relative to the stator on a common axis to generate a rotational output. The rotational output is provided to the fluid displacement member to power the fluid displacement member to one of move linearly along and rotate about the common axis. The stator includes one or more coils configured to power rotation of the rotor. The one or more coils extend circumferentially around and can be coaxial on the common axis.

Abstract: A spine stabilization and fusion system includes a lateral cage having a lateral cage bore hole. The system also includes a lateral cage insertion shaft comprising a leading end, a mid-portion, and a terminal end. A shape of the leading end matches a shape of the lateral cage bore hole such that the leading end mates with the lateral cage bore hole via a friction fit. The system also includes a lateral plate having a lateral plate bore hole and a plurality of holes, where the lateral plate bore hole receives the mid-portion of the lateral cage insertion shaft, and where the plurality of holes receive fasteners to couple the lateral plate to one or more vertebra.

Abstract: Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.

Abstract: A portable negative air pressure apparatus for isolating a treatment subject to permit a selected treatment procedure to be performed by a treatment operator. The apparatus comprises an air source connected to a closed chamber for sealable disposition over the head, neck and upper thorax of the treatment subject with the chamber having air ports, in and out. The chamber has rigid clear sides and a plurality of sealed ports, with the ports including sealed armholes for access, and with sealed gloves connected to the sealed armholes. The chamber also has at least one instrument hatch to permit introduction into the chamber of instruments for carrying-out the selected treatment procedure.

Abstract: The present disclosure provides compositions and methods for treatment of a kidney disease with chemokine protein stromal cell-derived factor 1 (SDF-1), such as methods of treating a subject afflicted with or at risk of developing a kidney disease, comprising administering SDF-1 to a kidney of the subject in a treatment-effective amount.

Abstract: A non-keyed clamping shaft collar with radial mounts is disclosed to provide maximum effective holding force for a mounting clamp against high torque, and which provides a means for precisely locating a counterbalance weight to minimize system torque without requiring any measurements or calculations of system masses or vectors. The counterbalance clamp comprises two concentric rings of different materials. The outer material is strong enough to prevent breaking under a maximum designed clamping force. The inner material has a high coefficient of static friction with the bar onto which it is clamped to prevent slipping after it is clamped. The outer ring has two tapped holes located 180 degrees opposite each other. The clamp enables the use of a lower clamping force, mitigating the potential to deform the bar as a result of the higher coefficient of static friction between the two sliding elements (the bar and the inner ring) being clamped together.

Abstract: An endovascular occlusion device. The endovascular occlusion device (300) has a balloon (306) and a catheter (304). The catheter (304) has a distal end (308), a proximal end, and a lumen (318) extending therebetween. The balloon (306) is positioned proximate to the distal end (308) of the catheter (304) and has a deflated state and an inflated state. The catheter (304) further includes a plurality of ports (314) proximate to a proximal end of the balloon (306). Each port (314) extends through a wall of the catheter (304) such that surface (316) of the catheter (304) is in fluid communication with the lumen (318) of the catheter (304). A flow restrictor (324) is positioned within, and is in sliding relation with, the lumen (318) of the catheter (304). Movement of the flow restrictor (324) is configured to close one or more ports (314) of the plurality so as to limit blood flow through the lumen (318) of the catheter (304).

Abstract: A method for alternative fuel life-cycle tracking includes electronically receiving, at a remote server, fuel data of fuel in a first container. The fuel comprises first and second batches. The fuel data includes first and second sets of alternative fuel identifiers (AFIs) associated with, respectively, a first unit of the first batch and a second unit of the second batch. The method further includes electronically receiving, at the remote server, a transfer volume of the fuel being transferred to a second container. The method further includes electronically transferring, at the remote server, first and second subsets, respectively, of the first and second sets of AFIs to be associated with the second container. The transfer of the first and second subsets is based on the transfer volume and a proportion of the first unit to the second unit.