Abstract: The invention relates to a compound of formula (I) in free form or in pharmaceutically acceptable salt form to pharmaceutical compositions comprising said compound and to the use of said compound in the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva.

Abstract: This application relates to various crystalline forms of 5-bromo-2,6-di(1H-pyrazol-1-yl)pyrimidin-4-amine and salt thereof, as well as compositions and methods of using the same. In some embodiments the crystalline forms also contain water (“hydrates”). These materials are useful in the treatment of various diseases, including carcinomas, specifically lung cancer and more specifically non-small cell lung cancer.

Abstract: The invention relates to a compound of formula (I) in free form or in pharmaceutically acceptable salt form to pharmaceutical compositions comprising said compound and to the use of said compound in the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva.

Abstract: A method and system for image reconstruction are provided. A projection image of a projection object may be obtained. A processed projection image may be generated based on the projection image through one or more pre-process operations. A reconstructed image including an artifact may be reconstructed based on the processed projection image. The artifact may be a detector edge artifact, a projection object edge artifact, and a serrated artifact. The detector edge artifact, the projection object edge artifact, and the serrated artifact may be removed from the reconstructed image.

Abstract: A refrigerating device used to reduce a temperature of drinks is provided and a higher refrigerating efficiency can be obtained through a control method and a control system thereof. The refrigerating device includes a pre-refrigeration unit used to pre-refrigerate a raw material; a main-refrigeration unit in communication with the pre-refrigeration unit and used to accommodate the pre-refrigerated raw material and refrigerate the raw material further; a dispenser in communication with the main-refrigeration unit and used to dispense the frozen drink in the main-refrigeration unit; and a refrigeration system providing a refrigerating capacity to the pre-refrigeration unit and the main-refrigeration unit.

Abstract: The invention relates to a compound of formula (I) in free form or in pharmaceutically acceptable salt form (I) to pharmaceutical compositions comprising said compound and to the use of said compound in the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva.

Abstract: The present disclosure relates to systems and methods for image splicing. The systems and methods may acquire a first image and a second image, determine a plurality of first feature points in a first region of the first image, determine a plurality of second feature points in a second region of the second image, then match the plurality of first feature points with the plurality of second feature points to generate a plurality of point pairs. Based on the plurality of point pairs, a third region on the first image and a fourth region on the second image may be determined. Finally, a third image may be generated based on the first image and the second image, wherein the third region of the first image may overlap with the fourth region of the second image in the third image.

Abstract: A plate heat exchanger is provided in the present application, which includes multiple first plates and multiple second plates which are alternately stacked together, first flow passages and second flow passages spaced from each other are formed between the first plates and the second plates, a first passage is formed by first orifices, a second passage is formed by second orifices, and the first passage and the second passage are in communication with each other via the first flow passages or the second flow passages to form a first fluid passage. At least one damping structure is provided in the first fluid passage, and at least a part of the first fluid passage is in communication with a first pipe or a second pipe via the damping structure.

Abstract: This application relates to various crystalline forms of 5-bromo-2,6-di(1H-pyrazol-1-yl)pyrimidin-4-amine and salt thereof, as well as compositions and methods of using the same. In some embodiments the crystalline forms also contain water (“hydrates”). These materials are useful in the treatment of various diseases, including carcinomas, specifically lung cancer and more specifically non-small cell lung cancer.

Abstract: A method and system for image reconstruction are provided. A projection image of a projection object may be obtained. A processed projection image may be generated based on the projection image through one or more pre-process operations. A reconstructed image including an artifact may be reconstructed based on the processed projection image. The artifact may be a detector edge artifact, a projection object edge artifact, and a serrated artifact. The detector edge artifact, the projection object edge artifact, and the serrated artifact may be removed from the reconstructed image.

Abstract: A method and system for image reconstruction are provided. A projection image of a projection object may be obtained. A processed projection image may be generated based on the projection image through one or more pre-process operations. A reconstructed image including an artifact may be reconstructed based on the processed projection image. The artifact may be a detector edge artifact, a projection object edge artifact, and a serrated artifact. The detector edge artifact, the projection object edge artifact, and the serrated artifact may be removed from the reconstructed image.

Abstract: The present disclosure relates to systems and methods for image splicing. The systems and methods may acquire a first image and a second image, determine a plurality of first feature points in a first region of the first image, determine a plurality of second feature points in a second region of the second image, then match the plurality of first feature points with the plurality of second feature points to generate a plurality of point pairs. Based on the plurality of point pairs, a third region on the first image and a fourth region on the second image may be determined. Finally, a third image may be generated based on the first image and the second image, wherein the third region of the first image may overlap with the fourth region of the second image in the third image.

Abstract: In an example, a method for managing a virtual network is provided. According to the method, first and second domains are respectively created for heterogeneous first and second hypervisor mangers. The first hypervisor manager manages a first virtual machine (VM) and first virtual switch (vSwitch) The second hypervisor manager manages a second VM and a second vSwitch. Based on topology of the virtual network, topology management information may be created, which comprises first and second virtual network topology information respectively for the first and second domains, and first and second configuration information respectively for the first and second vSwitches. The topology management information may be distributed to the first and second hypervisor mangers after being associated with the first and second domains, so to the first and second vSwitches implement packet forwarding between the first and second VMs according to the first and second configuration information respectively.

Abstract: A heat exchanger includes a first header pipe, a second header pipe, a third header pipe, a fourth header pipe and a plurality of flat tubes, the first header pipe is provided with a first space and a second space and a communicating passage for communicating the first space with the second space; when refrigerant flows from the first space of the first header pipe to the second header pipe along the flat tubes, a part of the refrigerant passes through the communicating passage and directly enters into the second space of the first header pipe, thus an overall flow resistance of the heat exchanger may be decreased to some extent. Besides, the flow quantity of the refrigerant in the third flow path is constant, however fluid state parameters may change, which may greatly improve the heat exchange capacity of the third flow path, thereby improving the heat exchange performance of the heat exchanger on the whole.

Abstract: The invention relates to a compound of formula (I) in free form or in pharmaceutically acceptable salt form (I) to pharmaceutical compositions comprising said compound and to the use of said compound in the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva.

Abstract: A method and system for image reconstruction are provided. A projection image of a projection object may be obtained. A processed projection image may be generated based on the projection image through one or more pre-process operations. A reconstructed image including an artifact may be reconstructed based on the processed projection image. The artifact may be a detector edge artifact, a projection object edge artifact, and a serrated artifact. The detector edge artifact, the projection object edge artifact, and the serrated artifact may be removed from the reconstructed image.

Abstract: A method and system for image reconstruction are provided. A projection image of a projection object may be obtained. A processed projection image may be generated based on the projection image through one or more pre-process operations. A reconstructed image including an artifact may be reconstructed based on the processed projection image. The artifact may be a detector edge artifact, a projection object edge artifact, and a serrated artifact. The detector edge artifact, the projection object edge artifact, and the serrated artifact may be removed from the reconstructed image.

Abstract: A method and system for image reconstruction are provided. A projection image of a projection object may be obtained. A processed projection image may be generated based on the projection image through one or more pre-process operations. A reconstructed image including an artifact may be reconstructed based on the processed projection image. The artifact may be a detector edge artifact, a projection object edge artifact, and a serrated artifact. The detector edge artifact, the projection object edge artifact, and the serrated artifact may be removed from the reconstructed image.

Abstract: A heat exchanger integrated assembly and a manufacturing method thereof are provided. The heat exchanger integrated assembly includes a heat exchanger, a mating portion and an adaptor, wherein the heat exchanger includes a first inlet and a first outlet; the mating portion includes a first side, a second side and a first hole and a second hole passing through the first side and the second side, and the mating portion further includes a first recessed portion formed on the first side and in communication with the first hole; and the adaptor includes a first passage in communication with the first hole and in communication with the first inlet via the first recessed portion, and a second passage in communication with the first outlet via the second hole. The heat exchanger is integrated with other parts and is connected to an expansion valve directly.

Abstract: A connecting member includes a first component and a second component fixed to each other, the first component includes a first mounting wall and a first area formed by denting from the first mounting wall, the second component includes a second mounting wall, a second area and a third area, the second mounting wall and the first mounting wall are hermetically fixed, the second area and the third area are both formed by denting from the second mounting wall, and the second area and the third area are arranged with space and are in communication with the first area; the second component further includes a first slot extending through the second area and a second slot extending through the third area, and the first slot and the second slot are provided for communication of the circulating tubes of the heat exchanger.