Abstract: Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.

Abstract: A component with a reflective substrate, a photoresist layer disposed on the reflective substrate, and a light diffusing layer sandwiched between the reflective substrate and the photoresist layer is provided. The light diffusing layer includes an outer metal oxide layer with an outer rough surface configured to diffuse laser light during laser interference lithography of the photoresist layer. The outer metal oxide is also configured to be reduced to a conductive metallic layer during electroplating of the substrate. The outer metal oxide layer includes a plurality of elongated light diffusing elements extending in an outward direction from the substrate such that the outer rough surface diffuses at least 90% of laser light during the laser interference lithography of the photoresist layer.

Abstract: Some embodiments provide a method for handling failure at one of several peer centralized components of a logical router. At a first one of the peer centralized components of the logical router, the method detects that a second one of the peer centralized components has failed. In response to the detection, the method automatically identifies a network layer address of the failed second peer. The method assumes responsibility for data traffic to the failed peer by broadcasting a message on a logical switch that connects all of the peer centralized components and a distributed component of the logical router. The message instructs recipients to associate the identified network layer address with a data link layer address of the first peer centralized component.

Abstract: A component with a reflective substrate, a photoresist layer disposed on the reflective substrate, and a light diffusing layer sandwiched between the reflective substrate and the photoresist layer is provided. The light diffusing layer includes an outer metal oxide layer with an outer rough surface configured to diffuse laser light during laser interference lithography of the photoresist layer. The outer metal oxide is also configured to be reduced to a conductive metallic layer during electroplating of the substrate. The outer metal oxide layer includes a plurality of elongated light diffusing elements extending in an outward direction from the substrate such that the outer rough surface diffuses at least 90% of laser light during the laser interference lithography of the photoresist layer.

Abstract: A thermally conductive board includes a metal substrate, a metal layer, a thermal conductive insulating polymer layer, and a ceramic material layer. The thermal conductive insulating polymer layer is located between the metal layer and the metal substrate. The ceramic material layer includes an upper ceramic layer or a lower ceramic layer, or includes both the upper ceramic layer and the lower ceramic layer. The upper ceramic layer is disposed between the metal layer and the thermal conductive insulating polymer layer, and the lower ceramic layer is disposed between the thermal conductive insulating polymer layer and the metal substrate.

Abstract: A power drive circuit includes a power conversion module, a plurality of gate drivers, a waveform processing unit, a control unit, a weighting unit, and a comparator. Each gate driver includes a drive resistance setting value. The waveform processing unit outputs a current absolute value waveform of an AC power. The weighting unit generates a trigger voltage. When the comparator determines that the current absolute value waveform is greater than the trigger voltage, the comparator outputs a slew rate control signal to each of the gate drivers. When the gate driver receives the slew rate control signal, each of the gate drivers decreases the drive resistance setting value of the gate driver.

Abstract: A self-sterilizing display device is applied to self-sterilizing with a UV light. The self-sterilizing display device includes a display, a light-incident layer, a light source, and a transparent protective layer. The light-incident layer is disposed above the display. The light source is disposed at a periphery of the light-incident layer, and a light-emitting surface of the light source faces to the light-incident layer. The transparent protective layer is disposed between the light-incident layer and the display. Herein, the light source can emit the UV light toward the light-incident layer for sterilizing an outer surface of the self-sterilizing display device by irradiation, and the transparent protective layer can filter out the UV light. Therefore, the surface can be sterilized by UV light, and the UV light can be prevented or reduced from being incident on the display below and damaging the display.

Abstract: A polyimide resin is obtained by polymerizing a modified polyphenylene ether resin with terminal amine groups and tetracarboxylic dianhydride. The polyimide has the following characteristics: the dissipation factor under 10 GHz electromagnetic wave is less than 0.0040; the water absorption rate is less than 0.3%; or, the temperature of glass transition is greater than 250° C.

Abstract: Systems and methods for optical communication are provided. For instance, a method for optical communication can include receiving, by a first coupling module, a power-on signal from a first electronic device coupled to the first coupling module. The method can also include relaying, by the first coupling module, a first optical signal to a second coupling module coupled to a second electronic device. The method can also include relaying, by the second coupling module, in response to receipt of the first optical signal, a second optical signal to the first coupling module. The method can also include activating, by the first coupling module, in response to receipt of the second optical signal, a data transfer circuit for relaying data via an optical communication interface between the first coupling module and the second coupling module.

Abstract: Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.

Abstract: Some embodiments provide a method for forwarding data messages at multiple edge nodes of a logical network that process data messages between a logical network and an external network. At a particular one of the edge nodes, the method receives a data message sent from a source machine in the logical network. The method performs network address translation to translate a source network address of the data message corresponding to the source machine into an anycast network address that is shared among the edge nodes. The method sends the data message with the anycast network address as a source network address to the external network. Each edge node receives data messages from source machines in the logical network and translates the source addresses of the data messages into the same anycast public network address prior to sending the data messages to the external network.

Abstract: A method to form a three-dimensional photonic crystal template with a gradient structure involves irradiating a photoresist composition of a thickness of at least 15 ?m from at least four laser beams to yield a periodic patterned with a percolating matrix of mass in constructive volumes of a cured photoresist composition and destructive volumes of voids free of condensed matter where the proportion of constructive volume displays a gradient from the irradiated surface to the substrate after development. For a given light intensity, photoinitiator concentration in the photoresist composition, and a given thickness, by irradiating for a relatively short period, a three-dimensional photonic crystal template displaying a gradient having greater constructive volume proximal the air interface forms and a relatively long irradiation period results in a gradient having greater constructive volume proximal the substrate.

Abstract: A power supply apparatus is coupled to an AC power source, a critical load, and a general load. The power supply apparatus includes a UPS, a generator system, a power conversion system, and a controller. The power conversion system includes a first power conversion path and a second power conversion path. The first power conversion path is connected to the critical load and an output side, and the second power conversion path is connected to the general load and an input side. The first power conversion path and the second power conversion path are jointly connected to a DC bus. When the controller determines that the AC power source is abnormal, the controller controls disconnecting the AC power source, and activates the UPS to supply power to the critical load so as to enable the first power conversion path and disable the second power conversion path.

Abstract: A metal clad substrate is disclosed. The metal clad substrate includes a metal baseplate, a metal layer, and a thermally conductive bonding layer disposed therebetween. The thermally conductive bonding layer includes a lower adhesive layer, a fiber-containing layer, and an upper adhesive layer. An upper side and a lower side of the upper adhesive layer contacts the metal layer and the fiber-containing layer, respectively. An upper side and a lower side of the lower adhesive layer contacts the fiber-containing layer and the metal baseplate, respectively. Each of the metal layer and the metal baseplate has a thickness of 0.3 mm - 15 mm. The fiber-containing layer includes a polymer as well as a heat conductive filler and a short fiber evenly dispersed in the polymer. The short fiber is in shape of a string and has a length of 5 µm-210 µm.

Abstract: A coaxial cable connector is provided in the present invention. The coaxial cable connector comprises a nut and a mandrel. The nut surrounds an axis, the nut comprising a body member and an extension member, the body member is connected to the extension member, and the body member has a threaded section. The mandrel surrounds the axis, arranged correspondingly to the nut, and includes a head and a body, the head is connected to the body. Wherein the mandrel is disposed passed through the nut, and when the mandrel is passed through the nut, the head is in contact with the body member of the nut through the threaded section, and the body is in close contact with the extension member.

Abstract: A method of controlling a power converter is provided. The power converter generates a three-phase output power by switching an input power through a plurality of switches. The method includes steps of: acquiring a three-phase output command corresponding to the three-phase output power; comparing the three-phase output command with a control carrier to acquire a voltage phase angle corresponding to the three-phase output command; acquiring a three-phase current value of the three-phase output power; detecting the voltage phase angle and a positive/negative change of the three-phase current value to decide a zero-sequence voltage; composing the zero-sequence voltage and the three-phase output command to acquire a three-phase output expected value; comparing the three-phase expected values with the control carrier to acquire a turned-on time of each switch; and switching the input power to adjust the three-phase output power according to the turned-on time of each switch.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media relate to a method for generating an avatar within a video communication platform. The system may receive a selection of an avatar model from a group of one or more avatar models. The system receives a first video stream and audio data of a first video conference participant. The system analyzes image frames of the first video stream to determine a group of pixels representing the first video conference participant. The system determines a plurality of facial expression parameter associated with the determined group of pixels. Based on the determined plurality of facial expression parameter values, the system generates a first modified video stream depicting a digital representation of the first video conference participant in an avatar form.

Abstract: A method of clamping an output current of a three-phase power converter is provided. The three-phase power converter includes three switching bridge arms and provides a three-phase output voltage command, and each switching bridge arm has an upper switch and a lower switch connected in series. The method includes steps of: determining that the output current is greater than a first current threshold to activate a current clamping control procedure, comparing a carrier signal with the three-phase output voltage command to turn on the lower switches by a first zero vector when the carrier signal is rising and turn on the upper switches by a second zero vector when the carrier signal is falling, determining that the output current is greater than a second current threshold to activate an overcurrent protection procedure, wherein the second current threshold is greater than the first current threshold.

Abstract: The present disclosure provides a device and method for diagnosing risk of insufficient hole cleaning problem during drilling wells. The method includes obtaining the measured pressure via several measuring points, and obtaining actually measured value of each measuring point; calculate the theoretical pressure at each measuring points by using the real-time operational data as inputs, evaluating a hole cleaning condition by applying a difference between a theoretical pressure drop and a measured pressure drop to a developed pressure driven hole cleaning model, which gives the risk of insufficient hole cleaning problems and problematic locations. The theoretical pressure drop between two adjacent measurement points along wellbore includes the pressure drop caused by friction effect and hydrostatic effect. However, suspended cuttings in actual drilling fluid may significantly change the pressure drop along wellbore.

Abstract: Hydantoin based compounds of formula (I) useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.