Abstract: Validation of a therapeutic radiation treatment involves using an applicator balloon surrounding an X-ray radiation source to support a plurality of X-ray sensor elements (XRSE). The XRSE are supported on the applicator balloon at distributed locations to sense applied radiation from the radiation source. At least one parameter of the applied radiation which has been sensed by the XRSE is compared to a corresponding parameter of a predetermined radiation treatment plan. Based on the comparing, a determination is made as to whether one or more requirements of the predetermined radiation treatment plan have been satisfied.

Abstract: X-ray delivery system includes a portable base unit to which a first end of a robotic arm is mounted. An X-ray treatment head is disposed on a second end of the robotic arm. The X-ray treatment head includes an X-ray component configured to generate therapeutic radiation in the X-ray wavelength range. A calibration well is disposed at a predetermined location in the portable base unit. The calibration well is comprised of a recess into which the X-ray treatment head can be received and having at least one port through which the X ray treatment head can be inserted by the robotic arm for calibration operations. The calibration well includes a plurality of X-ray radiation sensing elements disposed at distributed locations around a periphery of the calibration well.

Abstract: X-ray delivery system includes a portable base unit to which a first end of a robotic arm is mounted. An X-ray treatment head is disposed on a second end of the robotic arm. The X-ray treatment head includes an X-ray component configured to generate therapeutic radiation in the X-ray wavelength range. A calibration well is disposed at a predetermined location in the portable base unit. The calibration well is comprised of a recess into which the X-ray treatment head can be received and having at least one port through which the X ray treatment head can be inserted by the robotic arm for calibration operations. The calibration well includes a plurality of X-ray radiation sensing elements disposed at distributed locations around a periphery of the calibration well.

Abstract: Real-time X-ray dosimetry sensing in intraoperative radiation therapy (IORT). According to one aspect, a treatment head comprises at least one X-ray component configured to facilitate generation of therapeutic radiation in the X-ray wavelength range. A resilient balloon is disposed over the treatment head and configured for receiving therein a fluid to facilitate X-ray treatment of a tumor cavity. A plurality of X-ray sensing elements is disposed at a plurality of locations distributed on the interior or exterior of the resilient balloon and configured for sensing X-ray radiation emanating from the treatment head. A control system is provided that is responsive to data received from the X-ray sensing elements to determine a magnitude of X-ray radiation detected at each of the X-ray sensing elements.

Abstract: Aspects of the present disclosure involve systems, devices, and methods for detecting and treating skin conditions such as skin cancers; more particularly it relates to detection of skin cancers and superficial radiotherapy treatment thereof. The system uses Augmented Reality (“AR”) display systems that help visualize radiation patterns and overall tumor shape/size at least when setting up for radiotherapy treatment.

Abstract: A radiotherapy method for treatment of skin includes the step of applying radiation to a first region of interest of a person's skin using a radiotherapy device including a first filter having a first thickness and a first applicator having a first length. A flow of desired photons emitted from an x-ray tube of the radio therapy device is increased by (a) replacing the first applicator with a second applicator having a second length shorter than the first length, replacing the first filter with a second filter having a second thickness greater than the first thickness, and using a first dose rate less than one thousand centigray per minute, or (b) replacing the first applicator with the second applicator, using a third filter having a third thickness less than or equal to the first thickness, and using a second dose rate greater than one thousand centigray per minute.

Abstract: Systems and methods for treating a patient. The methods comprise: producing, by a radiotherapy system, a fused model for a superficial portion of the patient's skin by combining structural imaging data acquired using high frequency ultrasound and functional imaging data acquired using optical imaging; generating a treatment plan for the patient based on the fused model; storing the treatment plan; detecting, by a processor, an arrival of the patient at a medical facility using first information acquired from a first mobile device coupled to the patient; obtaining the treatment plan using the first information; and causing a state of medical equipment to be transitioned from a first configurable operational state in which a radiotherapy treatment head has a first position to a second configurable operational state in which the radiotherapy treatment head has a second different position, in accordance with the treatment plan.

Abstract: Three dimensional beam forming X-ray source includes an electron beam generator (EBG) to generate an electron beam. A target element is disposed a predetermined distance from the EBG and positioned to intercept the electron beam. The target element is responsive to the electron beam to generate X-ray radiation. A beam former is disposed proximate to the target element and comprised of a material which interacts with the X-ray radiation to form an X-ray beam. An EBG control system controls at least one of a beam pattern and a direction of the X-ray beam by selectively varying a location where the electron beam intersects the target element to control an interaction of the X-ray radiation with the beam-former.

Abstract: Intraoperative radiation therapy involves a treatment head disposed on a distal end of a robotic arm. An X-ray component included as part of the treatment head generates therapeutic radiation in the X-ray wavelength range. At least one patient motion sensor detects a breathing movement of a patient body. A control system dynamically controls a position of the treatment head by causing a position variation in at least one of the movable joints comprising the robotic arm. This movement is managed so that a relative motion as between the treatment head and a tumor bed internal of the patient is minimized.

Abstract: A radiotherapy system including a radiotherapy component, a structural imaging component, a functional imaging component, and a workstation coupled to the radiotherapy component, the structural imaging component, and the functional imaging component. The workstation includes a processor which combines the structural imaging data and the functional imaging data to produce a fused model for a least a portion of the region of interest, to generate a plan for radiotherapy treatment of the region of interest based on the fused model, and apply, via the radiotherapy component, the radiotherapy treatment.

Abstract: Virtual Dermatopathology Regional Hub (VDRH) receives one or more of the Detailed Virtual Tissue Models generated at one or more of the Virtual Dermatology Workstations and selectively communicates each to at least one pathology site. Each pathology site includes one or more Dermatopathology Information Processing Workstations (DIPWs). Thereafter, the VPM receives from the one or more of the pathology sites a plurality of pathology reports generated using said DIPWs and respectively corresponding to the plurality of DVTMs. The VPM then selectively communicates the pathology reports to the imaging facility which generated respectively the DVTM upon which each said pathology report is based.