Abstract: The present invention relates to a pharmaceutical composition comprising a weak acid drug, with the use of a bicarbonate salt to achieve a high incorporation of the drug into the liposome and a better therapeutic efficacy. Also disclosed is a method for treating a respiratory disease using the pharmaceutical composition disclosed herein.

Abstract: Provided are a complex of an anti-IL-4R antibody or an antigen-binding fragment thereof, and a medical use thereof. Specifically, provided are a complex of an antibody that specifically binds to IL-4R or an antigen-binding fragment thereof covalently linked to a toxin, a pharmaceutical composition comprising the complex, and a use thereof in the preparation of a drug for treating IL-4R-mediated diseases or disorders, especially a use in the preparation of an anti-cancer drug.

Abstract: A device includes: a complementary transistor including: a first transistor having a first source/drain region and a second source/drain region; and a second transistor stacked on the first transistor, and having a third source/drain region and a fourth source/drain region, the third source/drain region overlapping the first source/drain region, the fourth source/drain region overlapping the second source/drain region. The device further includes: a first source/drain contact electrically coupled to the third source/drain region; a second source/drain contact electrically coupled to the second source/drain region; a gate isolation structure adjacent the first and second transistors; and an interconnect structure electrically coupled to the first source/drain contact and the second source/drain contact.

Abstract: Provided is an application of a JAK inhibitor in kidney disease. Specifically, provided is a use of a JAK inhibitor in the preparation of a drug for treating or preventing kidney disease.

Abstract: A PVRIG binding protein and its medical uses. Specifically, an anti-PVRIG single-domain antibody and an anti-PVRIG and -TIGIT bispecific antibody, pharmaceutical compositions comprising the antibodies, a method for treating cancer, and pharmaceutical uses.

Abstract: Disclosed are an electrolytic reduction system of a vanadium electrolyte and a method for producing the electrolyte. The electrolytic reduction system includes a separating device and an electrolytic tank. The separating device is configured to separate a mixture consisting of a vanadium pentoxide (V2O5) solid and a sulfate acid solution, thereby obtaining a vanadium solution from a liquid discharging port of the separating device and a vanadium solid from a solid discharging port. The vanadium solution includes pentavalent vanadium ions. The electrolytic tank connects to the liquid discharging port of the separating device to contain the vanadium solution. In the method for producing the vanadium electrolyte, other chemical reagents are unnecessarily to be added into the mixture, and the vanadium solution is subjected to an electrolytic reduction process, such that the pentavalent vanadium ions are reduced to tetravalent vanadium ions and trivalent vanadium ions in the electrolytic tank.

Abstract: A projection apparatus including a housing and a first projection module is provided. The housing includes a curved projection area and an opening, wherein the curved projection area includes an inner surface and an outer surface opposite to each other. The first projection module is detachably disposed in the housing through the opening and corresponds to the curved projection area, wherein the first projection module projects an image onto the inner surface of the curved projection area, such that the outer surface of the curved projection area displays the projected image. The projection apparatus provided by the invention has the curved projection area to dynamically display a stereo image.

Abstract: There is provided a method comprising receiving at least one measured signal characteristic from a user equipment, the user equipment being located at a user equipment location; comparing the at least one measured signal characteristic to at least one of a plurality of signal characteristics, each signal characteristic being associated with a respective measurement point; and determining, based on the comparing, a probability that the user equipment location is a first location.

Abstract: The present invention relates to an anti-CD40 antibody, an antigen binding fragment and a pharmaceutical use thereof. Heavy-chain constant regions of the anti-CD40 antibody and the antigen binding fragment thereof contain mutations. Due to the mutations, the anti-CD40 antibody loses the binding activity to Fc?RIII, and the binding of the anti-CD40 antibody and Fc?RIIB is enhanced, thereby losing the antibody-dependent cytotoxicity (ADCC) but improving Fc?RIIB-mediated antibody crosslinking. The mutations in the heavy-chain constant regions enhance the activation of CD40, and enhance the presentation of dendritic cells to antigens. The anti-CD40 antibody and the antigen binding fragment thereof can be used as anti-cancer drugs to treat CD40-mediated diseases or symptoms.

Abstract: A curved shell, configured to receive a projection light beam provided by a projection device, and including a curved main body, a microstructure layer and multiple light-resistant layers is provided. The curved main body has an inner surface and an outer surface opposite to each other, and the outer surface has different curvatures. The microstructure layer is disposed on the outer surface and includes multiple first inclined surfaces and multiple second inclined surfaces distributed in alternation, and any two adjacent ones of the first inclined surfaces and the second inclined surfaces have an included angle. The light-resistant layers are disposed on the first inclined surfaces, wherein the light-resistant layers reflect or absorb ambient light beams from the outside of the curved main body, and the inner surface receives the projection light beam, and the projection light beam passes through the second inclined surfaces to form a projection image.

Abstract: A system for controlling operation of an electric device includes the electric device, at least one contactless sensor module connected to the electric device, and a wearable item equipped with a sensor-readable tag configured for contactless interaction with the contactless sensor of the electric device. The tag is configured for movement with the wearable item into a plurality of different positions relative to the contactless sensor, and the contactless sensor is configured to sense different sensor readings in response to movement of the tag into the plurality of different positions. The electric device is configured to enter a first operating mode in response to the contactless sensor sensing a first position of the tag, and to enter a second operating mode in response to the contactless sensor sensing a second position of the tag.

Abstract: A projection apparatus including a housing and a first projection module is provided. The housing includes a curved projection area and an opening, wherein the curved projection area includes an inner surface and an outer surface opposite to each other. The first projection module is detachably disposed in the housing through the opening and corresponds to the curved projection area, wherein the first projection module projects an image onto the inner surface of the curved projection area, such that the outer surface of the curved projection area displays the projected image. The projection apparatus provided by the invention has the curved projection area to dynamically display a stereo image.

Abstract: A channel plate structure includes a nonreactive portion and an electrochemical reactive portion. The nonreactive portion includes at least one manifold inlet, at least one manifold outlet, flow channels, and cutoff structures. The cutoff structures are respectively disposed in the flow channels, and the ratio of the total area of the cutoff structures to the area of the channel plate structure is 0.002 to 0.01 based on battery size. Each of the cutoff structures includes a gas-liquid separation compartment, a joint portion, and a convergent portion, wherein a width of the joint portion is smaller than or equal to that of the gas-liquid separation compartment, the convergent portion connects the gas-liquid separation compartment to the joint portion, and the cross-sectional area of a flow path at an downstream end of the convergent portion is smaller than that of the flow path at an upstream end of the same.

Abstract: An electrolyte composition and an energy storage device employing the same are provided. The electrolyte composition includes a solid and a solution. The solid includes a core and a metal layer encapsulating the core, where the metal layer is selected from a group consisting of Zn, Al, Mg, Li, Na and the metal oxides thereof. In particular, the solid has a first density and the solution has a second density, and the ratio between the first density and the second density is from about 0.97 to 1.03.

Abstract: The invention provides a projector which is characterized by including a housing, a control module and a sensor. The housing is provided with a mounting structure and at least one air flowing hole. The mounting structure is located inside the housing, and the air flowing hole communicates with external environment and an interior of the housing. The control module is disposed inside the housing. The sensor is arranged on the mounting structure and aligns to the air flowing hole. The sensor is electrically connected with the control module, and the sensor receives a remote control optical signal from the external environment to generate an electrical signal and the sensor transmits the electrical signal to the control module. In this way, the manufacturing process of the projector is simplified and the manufacturing cost is reduced.

Abstract: The invention provides a projector which is characterized by including a housing, a control module and a sensor. The housing is provided with a mounting structure and at least one air flowing hole. The mounting structure is located inside the housing, and the air flowing hole communicates with external environment and an interior of the housing. The control module is disposed inside the housing. The sensor is arranged on the mounting structure and aligns to the air flowing hole. The sensor is electrically connected with the control module, and the sensor receives a remote control optical signal from the external environment to generate an electrical signal and the sensor transmits the electrical signal to the control module. In this way, the manufacturing process of the projector is simplified and the manufacturing cost is reduced.

Abstract: A channel plate structure includes a nonreactive portion and an electrochemical reactive portion. The nonreactive portion includes at least one manifold inlet, at least one manifold outlet, flow channels, and cutoff structures. The cutoff structures are respectively disposed in the flow channels, and the ratio of the total area of the cutoff structures to the area of the channel plate structure is 0.002 to 0.01 based on battery size. Each of the cutoff structures includes a gas-liquid separation compartment, a joint portion, and a convergent portion, wherein a width of the joint portion is smaller than or equal to that of the gas-liquid separation compartment, the convergent portion connects the gas-liquid separation compartment to the joint portion, and the cross-sectional area of a flow path at an downstream end of the convergent portion is smaller than that of the flow path at an upstream end of the same.

Abstract: An electrolyte composition and an energy storage device employing the same are provided. The electrolyte composition includes a solid and a solution. The solid includes a core and a metal layer encapsulating the core, where the metal layer is selected from a group consisting of Zn, Al, Mg, Li, Na and the metal oxides thereof. In particular, the solid has a first density and the solution has a second density, and the ratio between the first density and the second density is from about 0.97 to 1.03.

Abstract: An electrode structure of a fuel cell for power generation comprises an anodic structure, a cathodic structure, and an ionic exchange membrane disposed between the anodic and cathodic structures. The anodic and cathodic structures respectively are formed by multi-layer structures, to reduce the fuel crossover from the anodic structure to the cathodic structure, to reduce the catalysts applied amount, and to increase an output electrical energy of the fuel cell. The multi-layer structure of the anodic structure comprises a thin platinum alloy black layer, a Pt alloy layer disposed on the carbon material, and a substrate.

Abstract: A method for fabricating a bi-polar plate of a fuel cell and the bi-polar plate thereof are presented. A graphite film is formed first. Next, a polymeric material added with electrically conductive powder is coated on a surface of a metal substrate. The graphite film is disposed on the polymeric material and the polymeric material is hardened to form an adhesive layer, such that the graphite film is attached on the surface of the metal substrate.