Abstract: A multiple capsule camera apparatus is disclosed to enhance the rate of detection and/or extend the overall imaging period. The multiple capsule camera apparatus coordinates the operations of the camera according to a schedule so that one camera may enter an active mode when the other camera is anticipated to have a low battery level. The capsule cameras may also coordinate their operations by communication with each other through a wireless link. A base station may also be used to coordinate the capsule camera operations with a wireless link established between the base station and each capsule camera.

Abstract: A capsule camera with on-board storage to archive the captured images in on-board non-volatile memory is disclosed. The capsule camera with on-board storage comprises multiple chips including a system processing chip and one or more non-volatile memory chips, where the system processing chip includes a compression module to compress images captured. If the multiple chips use individual chip packages and are disposed on respective printed circuit boards according to a conventional approach, it would require too much space to fit the multiple chips into the capsule camera housing. Accordingly, a capsule camera embodying the present invention is disclosed where the capsule camera integrates an image sensor, a light source, at least one system processing chip comprising compression module, one or more non-volatile memory chips and a battery into a housing, wherein the at least one system processing chip and said one or more non-volatile memory chips are disposed vertically in a multiple chip assembly.

Abstract: A capsule camera with on-board storage to archive the captured images in on-board non-volatile memory is disclosed. The capsule camera with on-board storage comprises multiple chips including a system processing chip and one or more non-volatile memory chips, where the system processing chip includes a compression module to compress images captured. If the multiple chips use individual chip packages and are disposed on respective printed circuit boards according to a conventional approach, it would require too much space to fit the multiple chips into the capsule camera housing. Accordingly, a capsule camera embodying the present invention is disclosed where the capsule camera integrates an image sensor, a light source, at least one system processing chip comprising compression module, one or more non-volatile memory chips and a battery into a housing, wherein the at least one system processing chip and said one or more non-volatile memory chips are disposed vertically in a multiple chip assembly.

Abstract: Method and Systems are provided for presenting in-vivo image data. In order to increase the efficiency of viewing computed spectral sequences, the computed spectral sequences are generated according to a set of spectral patterns and the multiple computed spectral sequences are displayed using multiple display windows on one or more display devices. Various aspects of user interface related to presentation of concurrent presentation of computed spectral sequences are addressed. Graphic representation corresponding to the spectral pattern associated with said each computed spectral sequence can be displayed. Furthermore, user interface to select a set of spectral patterns from a plurality of sets of spectral patterns can be provided. The method may further comprise providing user interface to modify one or more parameters of the spectral pattern associated with a selected spectral color image.

Abstract: A method is provided for characterizing manufacturing variations in a camera and imperfections in its operating environment to allow images captured by the camera to be compensated for these defects. In one embodiment, a method for characterizing a camera includes: (a) illuminating a field of view of the optical elements under a controlled condition; (b) exposing multiple images onto the image sensor under the controlled condition; (c) extracting parameter values of a model for the image provided on the image sensor from the multiple images; and (d) compensating images taken subsequently in the camera using the parameter values. The objects in the field of view may have a predetermined color, contrast or pattern. In one instance, the controlled condition includes an external light source for illuminating the field of view, and the image sensor is sensitive to a plurality of color components. The field of view may be illuminated at a predetermined light intensity for each of the color components.

Abstract: A capsule camera with on-board storage to archive the captured images in on-board non-volatile memory is disclosed. The capsule camera with on-board storage comprises multiple chips including a system processing chip and one or more non-volatile memory chips, where the system processing chip includes a compression module to compress images captured. If the multiple chips use individual chip packages and are disposed on respective printed circuit boards according to a conventional approach, it would require too much space to fit the multiple chips into the capsule camera housing. Accordingly, a capsule camera embodying the present invention is disclosed where the capsule camera integrates an image sensor, a light source, at least one system processing chip comprising compression module, one or more non-volatile memory chips and a battery into a housing, wherein the at least one system processing chip and said one or more non-volatile memory chips are disposed vertically in a multiple chip assembly.

Abstract: A multiple capsule camera apparatus is disclosed to enhance the rate of detection and/or extend the overall imaging period. The multiple capsule camera apparatus coordinates the operations of the camera according to a schedule so that one camera may enter an active mode when the other camera is anticipated to have a low battery level. The capsule cameras may also coordinate their operations by communication with each other through a wireless link. A base station may also be used to coordinate the capsule camera operations with a wireless link established between the base station and each capsule camera.

Abstract: A method for detecting a capsule camera entering into or exiting the GI tract, includes (a) taking a first test image under the condition that an illumination system of the capsule camera is disabled; (b) taking a second test image under the same condition as the first test image; (c) comparing selected corresponding pixel values of the first test image and the second test image to determine if a significant change in pixel values has occurred; and (d) upon detecting the significant change in pixel values, determining if the capsule camera has entered or exited the GI tract, and performing operations appropriate to follow such determination.

Abstract: Systems and methods are provided for environment change sensing corresponding to the capsule camera entering the colon from the small intestine. In the environment change sensing mode, the capsule camera is operated in a very low power mode by configuring the image sensor to use a small region of interest or a high sub-sampling ratio. Image data is processed to estimate the light level. The variation of light level is used to detect environment change corresponding to entering the colon from the small intestine. Alternatively, the motion metric for a current frame and a reference frame is evaluated. The characteristic of the motion metric is extracted and used to detect environment change. In another configuration, the system determines environment change based on a combination of the variation of light intensity and the characteristic of the motion metric.

Abstract: A method for detecting a capsule camera entering into or exiting the GI tract, includes (a) taking a first test image under the condition that an illumination system of the capsule camera is disabled; (b) taking a second test image under the same condition as the first test image; (c) comparing selected corresponding pixel values of the first test image and the second test image to determine if a significant change in pixel values has occurred; and (d) upon detecting the significant change in pixel values, determining if the capsule camera has entered or exited the GI tract, and performing operations appropriate to follow such determination. The appropriate operations performed after detecting the capsule camera's exit from the GI tract includes stopping further taking or storing of images and, optionally, activating an audio signal to indicate the capsule camera has exited the GI tract.

Abstract: Systems and methods for a capsule camera having on-board storage or wireless transmission to control image capture using motion information and to encode captured images based on motion compensated video compression are disclosed. In order to conserve the precious storage and power resources, the capsule camera measures motion metric to select a skip mode or a capture mode. In order to reduce computations related motion metric derivation, the motion metric is based on sub-images corresponding to a current frame and a previous captured frame instead of full-size images. When the skip mode is selected, the capsule camera exercises storage space/power conservation by skipping unnecessary image capture and/or reducing luminous energy of a light source or other means for power conservation. When the capture mode is selected, a full-size full-resolution frame is captured and compressed using motion-compensated video compression to achieve high compression ratio.

Abstract: Systems and methods are provided for displaying images captured from a panoramic capsule camera system. In one embodiment according to the invention, multiple sub-image sets are generated using a sub-image set window on the panoramic image by cyclically shifting the panoramic image. The multiple sub-image sets are then displayed in multiple display windows. In another embodiment according to the invention, the sub-image set in every other display window is flipped horizontally, vertically or both horizontally and vertically.

Abstract: Systems and methods are provided for identifying dark areas in images captured by encapsulated cameras or endoscopes and enhancing the visibility of the dark area using intensity stretch. For capsule or endoscope images, there are often some dark areas caused by inadequate lighting. The poor visibility of detailed features in the dark area may reduce the detection rate of anomaly. The present invention calls for a method to detect the dark area based on contour. The intensities inside and outside the dark area are evaluated and are used to generate intensity transformation to stretch intensity in the dark area while minimizing the impact on the image quality outside the dark area.

Abstract: Systems and methods are provided for displaying images captured from a capsule camera system. In order to increase the efficiency of viewing the image sequence, the image sequence is divided into multiple sub-sequences and the multiple sub-sequences are displayed in multiple viewing windows on a display screen concurrently. For images from a panoramic capsule system, the images typically have a very wide aspect ratio and may require different configuration for displaying in multiple viewing windows than that for image sequence having non-wide aspect ratio. The present invention also discloses methods and systems that divide a sequence from panoramic capsule camera into multiple member sequences and form an aggregated video. The aggregated video not only makes viewing more comfortable, but also speeds up viewing time.

Abstract: Systems and methods are provided for capsule location determination. There is a need to estimate the capsule location in a living body for drug dispensing, correlating capsule images with actual tract location and other purposes. A capsule location determining system is disclosed which comprises a plurality of sensing devices and a base station. Each sensing device comprises a radiating element to radiate an inducing signal, a generating circuit to provide a patterned signal to drive the radiating element, a sensing element to sense the induced field and a receiving circuit to provide a recovered signal. The base station estimates the capsule location based on a time profile of collected information related to the recovered signals from all sensing devices. Methods associated with the capsule location determining systems are also disclosed.

Abstract: A capsule camera apparatus includes a swallowable housing, a light source within the housing, a camera within the housing for capturing a first digital image and a second digital image of a view of the camera illuminated by the light source, a motion detector that detects a motion of the housing the first digital image and the second digital image, and a motion evaluator that selects a disposition of the second digital image, based on a metric on the motion. The disposition may include writing the second image into an archival storage or providing the second digital image to the outside by a wireless communication link.

Abstract: A capsule camera apparatus includes a swallowable housing, a light source within the housing, a camera within the housing for capturing a first digital image and a second digital image of a view of the camera illuminated by the light source, a motion detector that detects a motion of the housing the first digital image and the second digital image, and a motion evaluator that selects a disposition of the second digital image, based on a metric on the motion. The disposition may include writing the second image into an archival storage or providing the second digital image to the outside by a wireless communication link.

Abstract: A capsule camera apparatus includes a swallowable housing, a light source within the housing, a camera within the housing for capturing a first digital image and a second digital image of a view of the camera illuminated by the light source, a a motion detector that detects a motion of the housing the first digital image and the second digital image, and a motion evaluator that selects a disposition of the second digital image, based on a metric on the motion. The disposition may include writing the second image into an archival storage or providing the second digital image to the outside by a wireless communication link.

Abstract: Systems and methods are provided for capture control of video data from a capsule camera system having an on-board storage or wireless transmission. The capsule camera system moves through the GI tract under the action of peristalsis and records images of the intestinal walls. For some periods of time, the capsule camera system may move very slowly and there are little differences in the image data between different frames. These frames can be designated for discard to conserve storage space or conserve power. A capsule control processing unit is incorporated to evaluate motion metric based on image data associated with a current frame and a previous frame. A decision is made based on a profile of the motion metric to select an operation mode from a group comprising Capture Mode and Conservation Mode. The capsule camera system is then operated according to the selected operation mode.

Abstract: Systems and methods are provided for display speed control of images captured from a capsule camera system. For capsule systems, with either digital wireless transmission or on-board storage, the captured images will be played back for analysis and examination. During playback, the diagnostician wishes to find polyps or other points of interest as quickly and efficiently as possible. The present invention discloses systems and methods for display speed based on image complexity. A higher visual complexity will result in longer display time so that the diagnostician can examine the underlying images longer. Conversely, a lower visual complexity will result in shorter display time. The visual complexity may be derived from image contours/edges or spatial frequencies.