Abstract: Provided are antibodies that specifically bind to Programmed Death-1 (PD1, Pdcd-1, or CD279) ligand (PD-L1) and inhibit PD-L1-mediated cellular signaling and activities in immune cells, antibodies binding to a set of amino acid residues required for its ligand binding, and uses of these antibodies to treat or diagnose cancer, infectious diseases or other pathological disorders modulated by PD-L1-mediated functions.

Abstract: A lower limb exoskeleton system includes a back frame, hip joint movement mechanisms, telescopic thigh bars, knee joint movement mechanisms, shank bars, foot jump-down cushioning mechanisms, a waist binding frame, upper leg binding frames and lower leg binding frames. Two protruding ends of the back frame are connected with one end of each of the telescopic thigh bars respectively via the hip joint movement mechanisms, the other ends of the telescopic thigh bars are connected with one end of the corresponding shank bars respectively via the knee joint movement mechanisms, and the other ends of the shank bars are connected with the foot jump-down cushioning mechanisms. The waist binding frame is arranged on an inner side of a horizontal part of the back frame, and the upper leg binding frames and the lower leg binding frames are arranged on the telescopic thigh bars and the shank bars respectively.

Abstract: A method and device for monitoring a fault of a wind power generator set. The method includes the following steps: performing (101) fault identification on a component in a wind power generator set; and presenting (102) an identified fault using a three-dimensional model of the component. The device includes corresponding identifying module (61) and presenting module (62). By using the method and device, the fault monitor can intuitively observe the fault existed in the component, which not only is beneficial for taking effective fault processing measures before a minor fault evolves into a serious fault and thus reduces the harm of the fault, but also reduces the experience requirements for the fault monitor and avoids the process that the fault monitor in the prior art analyzes a two-dimensional curve to identify whether there is a fault in the component according to his experience.

Abstract: The present invention discloses a drilling system and method of a submarine drilling rig, relating to the technical field of drilling equipment. The system includes a barge, an umbilical cable, a submarine device and a drilling device; where the barge is loaded with a pneumatic-electric-hydraulic control device and a mud treatment device which are respectively connected to the submarine device through the umbilical cable; and the submarine device includes a submarine traveling device, a coiled tubing roller, a derrick, a centralized valve seat, a drill bit replacement device, a wellhead device and a casing rack. The centralized valve seat is connected to the umbilical cable for shunting mud, cement and electrical signals conveyed by the umbilical cable. The derrick is installed above the wellhead device, respectively matched with the drill bit replacement device and the casing rack for replacing drill bits and conveying and withdrawing casings.

Abstract: A load driver for driving a load and an LED module are disclosed. In one embodiment, the load driver comprises a converter circuit comprising a controllable switching element configured to be turned on and off and to perform power factor correction for power from a power supply to the load, wherein a control terminal of the controllable switching element is configured for receiving a startup current via the two output terminals, the controllable switching element configured to be turned on by the startup current. The converter circuit further comprises a first inductor, coupled to the power supply at a first end, and to ground at a second end via the controllable switching element, wherein a first one of the output terminals connects to a second end of the first inductor via a diode forwarded from the first inductor, a second one of the output terminals is coupled to the first end of the first inductor.

Abstract: Known catalytic converters consist of a ceramic honeycomb monolith substrate and a platinum group metal (PGM) catalytically active coating. A catalytic convertor comprising a substrate body (100) arranged within the catalytic convertor such that a principal flow of fluid through the catalytic convertor flows along a surface (101) of the substrate body, wherein said surface (101) has a plurality of openings (210) to micro-channels that extend away from said surface (101); and at least a portion of the surface (101) of the substrate body (100) comprises a catalytically active material, wherein the substrate body (100) is in the form of: a pellet; a sheet; solid elongate bodies; solid rods; a solid body having a plurality of bores; a non-tubular elongate body; a non-hollow body; a sheet curved in the form or a spiral; or a combination thereof.

Abstract: A luminaire (1) is disclosed comprising at least one optical chamber (10) delimited by a light exit window (11) and a curved reflective surface (15) extending from the light exit window to a mounting surface (17) extending from the curved reflective surface towards the light exit window. Each optical chamber comprises a light source (20) mounted on the mounting surface; and a light guide (30) extending across part of the optical chamber. The light guide comprises a total internal reflection major surface (40) facing the light exit window; a further major surface (50) facing the curved reflective surface, said further major surface comprising a light outcoupling portion (51) comprising a plurality of light outcoupling structures (53); a first edge surface (60) optically coupled to the light source; and a further edge surface (70) opposite the first edge surface arranged to direct light towards the curved reflective surface.

Abstract: A method and a terminal device for providing a suspend button display are disclosed in order to improve display flexibility of a suspend button. In the solutions, when a terminal device detects that a target object performs a sliding operation on a suspend button, the terminal device may control the suspend button to present an effect of a dynamic change. In this way, the suspend button may present a plurality of display forms. Therefore, according to the method, the display flexibility of the suspend button can be improved, so that visual experience of a user is improved.

Abstract: Embodiments of this application relate to the field of terminal technologies, and describe a method for displaying a dynamic image and a terminal, which resolve a problem that power consumption of a terminal caused by an existing method in which three-dimensional real-time rendering is used is relatively high. The method may be applied to a terminal, and can includes obtaining, from a video file based on a preset factor, a plurality of pieces of image frame data in a one-to-one correspondence to a plurality of image frames. The method may also include decoding the plurality of pieces of image frame data, to obtain the plurality of image frames. Furthermore, the method can include successively displaying the plurality of image frames obtained through the decoding, to present the dynamic image. The dynamic image includes the plurality of image frames, and the preset factor includes at least one of the following factors: a time point and orientation data.

Abstract: A navigation and positioning device including a storage, a mark feature analyzer, a first coordinate fusion component and a second coordinate fusion component is provided. The storage stores map information including a traffic mark feature and its mark coordinate. The mark feature analyzer is used for analyzing whether a captured image has the traffic mark feature. When the captured image has the traffic mark feature, the mark feature analyzer analyzes the traffic mark feature in the captured image and calculates a device coordinate according to the mark coordinate. The first coordinate fusion component fuses the device coordinate and a first fusion coordinate and uses fused coordinate as a second fusion coordinate. The second coordinate fusion component fuses the second fusion coordinate, traffic carrier inertial information and a global positioning coordinate and uses fused coordinate as an updated first fusion coordinate.

Abstract: Provided are antibodies that specifically bind to Programmed Death-1 (PD1, Pdcd-1, or CD279) and inhibit PD1-mediated cellular signaling and activities in immune cells, antibodies binding to a set of amino acid residues required for its ligand binding, and uses of these antibodies to treat or diagnose cancer, infectious diseases or other pathological disorders modulated by PD1-mediated functions.

Abstract: This application relates to the field of image processing, and provides an image processing method and an apparatus, so as to add a diffuse reflection effect to a projection image in real time and reduce a calculation volume required for adding the diffuse reflection effect. The specific solution includes: obtaining a first image that includes a diffuse reflection object, where the first image is an image obtained when the diffuse reflection object is illuminated by a light source; obtaining a mask image corresponding to the diffuse reflection object; obtaining orientation information of a terminal; and obtaining a second image based on the orientation information, the first image, and the mask image, where the second image is an image that includes the diffuse reflection object and a diffuse reflection effect and that is generated by superposing the first image and the mask image moved based on the orientation information.

Abstract: Embodiments of three-dimensional (3D) memory devices formed by bonded semiconductor devices and methods for forming the same are disclosed. In an example, a method for forming a bonded semiconductor device includes the following operations. First, a first wafer and a second wafer are formed. The first wafer can include a functional layer over a substrate. Single-crystalline silicon may not be essential to the substrate and the substrate may not include single-crystalline silicon. The first wafer can be flipped to bond onto the second wafer to form the bonded semiconductor device so the substrate is on top of the functional layer. At least a portion of the substrate can be removed to form a top surface of the bonded semiconductor device. Further, bonding pads can be formed over the top surface.

Abstract: A lane changing system includes an inertia-detecting unit for detecting a vehicle speed, an acceleration, and body parameters of a vehicle, a geographic information unit for detecting a real-time position of the vehicle and storing road-borderline information, a visual tracker for detecting a road curvature and a relative distance and capturing a road-borderline image and a vehicle-surrounding image, a memory storing vehicle parameters, a processor, and a rotation device. The processor calculates a lateral acceleration according to the vehicle parameters, the vehicle speed, the acceleration, and the road curvature. The processor generates a steering signal when the processor determines that the relative distance is less than a first threshold, the lateral acceleration is less than a second threshold, and there is no other vehicle around the vehicle. The rotation device receives the steering signal to for making the vehicle change from an original vehicle lane to an adjacent vehicle lane.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for implementing blockchain-based private transactions are provided. One of the methods is performed by a first blockchain node to a private transaction, the method including: determining one or more second blockchain nodes to the private transaction according to a blockchain contract in a public blockchain; transmitting transaction information to the one or more second blockchain nodes, the transaction information comprising one or more senders of the private transaction, one or more recipients of the private transaction, and one or more transaction amounts of the private transaction; obtaining a signature from each of a number of the one or more second blockchain nodes certifying receipt of the transaction information; and in response to obtaining the number of the signatures over a threshold, storing at least a representation of the private transaction and the signatures in the public blockchain.

Abstract: Disclosed herein is a pharmaceutical combination for use in the prevention, delay of progression or treatment of cancer, wherein the pharmaceutical combination exhibits a synergistic efficacy. The pharmaceutical combination comprises a humanized antagonist monoclonal antibody against PD- and a RAF inhibitor. Also disclosed herein is a combination for use in the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject a therapeutically effective amount of a humanized antagonist monoclonal antibody against PD-1 and a therapeutically effective amount of a RAF inhibitor.

Abstract: Disclosed herein is a method for the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject in need thereof a PARP inhibitor, particularly, (R)-2-fluoro-10a-methyl-7,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[def]cyclopenta[a]fluoren-4(5H)-one, a sesqui-hydrate thereof, or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor or a chemotherapeutic agent. Also, disclosed a pharmaceutical combination comprising a PARP inhibitor, particularly, (R)-2-fluoro-10a-methyl-7,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[def]cyclopenta[a]fluoren-4(5H)-one, a sesqui-hydrate thereof, or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor, or a chemotherapeutic agent and the use thereof.

Abstract: Provided are antibodies that specifically bind to Programmed Death-1 (PD1, Pdcd-1, or CD279) ligand (PD-L1) and inhibit PD-L1-mediated cellular signaling and activities in immune cells, antibodies binding to a set of amino acid residues required for its ligand binding, and uses of these antibodies to treat or diagnose cancer, infectious diseases or other pathological disorders modulated by PD-L1-mediated functions.

Abstract: Provided are antibodies that specifically bind to Programmed Death-1 (PD1, Pdcd-1, or CD279) and inhibit PD1-mediated cellular signaling and activities in immune cells, antibodies binding to a set of amino acid residues required for its ligand binding, and uses of these antibodies to treat or diagnose cancer, infectious diseases or other pathological disorders modulated by PD1-mediated functions.