Patents by Inventor Karen J. McGovern

Karen J. McGovern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF
    Publication number: 20230295147
    Abstract: The present invention provides AHR agonists, compositions thereof, and methods of using the same.
    Type: Application
    Filed: February 9, 2023
    Publication date: September 21, 2023
    Inventors: Alfredo C. CASTRO, Karen J. McGovern, Michael Burke
  • Aryl hydrocarbon receptor (AHR) agonists and uses thereof
    Patent number: 11608329
    Abstract: The present invention provides AHR agonists, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: March 21, 2023
    Assignee: IKENA ONCOLOGY, INC.
    Inventors: Alfredo C. Castro, Karen J. McGovern, Michael Burke
  • Methods of use of cyclopamine analogs
    Patent number: 11602527
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: March 14, 2023
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF
    Publication number: 20210300912
    Abstract: The present invention provides AHR agonists, compositions thereof, and methods of using the same.
    Type: Application
    Filed: December 18, 2020
    Publication date: September 30, 2021
    Inventors: Alfredo C. Castro, Karen J. McGovern, Michael Burke
  • METHODS OF USE OF CYCLOPAMINE ANALOGS
    Publication number: 20210275508
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: September 28, 2020
    Publication date: September 9, 2021
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF
    Publication number: 20210230153
    Abstract: The present invention provides AHR agonists, compositions thereof, and methods of using the same.
    Type: Application
    Filed: December 18, 2020
    Publication date: July 29, 2021
    Inventors: Alfredo C. Castro, Karen J. McGovern, Michael Burke
  • Methods of use of cyclopamine analogs
    Patent number: 10821102
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: November 3, 2020
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • METHODS OF USE OF CYCLOPAMINE ANALOGS
    Publication number: 20200022962
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: April 26, 2019
    Publication date: January 23, 2020
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • Methods of use of cyclopamine analogs
    Patent number: 10314827
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: June 11, 2019
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • METHODS OF USE OF CYCLOPAMINE ANALOGS
    Publication number: 20180338962
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: July 27, 2018
    Publication date: November 29, 2018
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • Methods of use of cyclopamine analogs
    Patent number: 10045970
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: August 14, 2018
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • METHODS OF USE OF CYCLOPAMINE ANALOGS
    Publication number: 20170360763
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: May 2, 2017
    Publication date: December 21, 2017
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • Methods of use of cyclopamine analogs
    Patent number: 9669011
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: June 6, 2017
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • METHODS OF USE OF CYCLOPAMINE ANALOGS
    Publication number: 20160158208
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: August 31, 2015
    Publication date: June 9, 2016
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • Methods of use of cyclopamine analogs
    Patent number: 9145422
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: September 29, 2015
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • METHODS AND COMPOSITIONS FOR IDENTIFICATION, ASSESSMENT AND TREATMENT OF CANCERS ASSOCIATED WITH HEDGEHOG SIGNALING
    Publication number: 20150025012
    Abstract: Provided herein are methods, assays and kits for evaluating a sample, e.g., a sample obtained from a cancer patient, to detect one or more hedgehog biomarkers and/or one or more cilium markers. Thus, the invention can be used, inter alia, as a means to identify patients likely to benefit from administration of one or more hedgehog inhibitors, alone or in combination with therapeutic agents; to predict a time course of disease or a probability of a significant event in the disease of a cancer patient; to stratify patient populations; and/or to more effectively treat or prevent a cancer or a tumor associated with hedgehog signaling.
    Type: Application
    Filed: August 8, 2014
    Publication date: January 22, 2015
    Inventors: John R. MacDougall, Juan Guillermo Paez, Karen J. McGovern, Jeffery L. Kutok, Georgios Skliris, Kerry White, Kerrie L. Faia, Marisa Osswalt Peluso, Veronica Travaglione Campbell
  • Methods of use of cyclopamine analogs
    Patent number: 8895576
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: November 25, 2014
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • METHODS OF USE OF CYCLOPAMINE ANALOGS
    Publication number: 20140107142
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: October 15, 2013
    Publication date: April 17, 2014
    Applicant: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay, William Matsui
  • METHODS OF USE FOR CYCLOPAMINE ANALOGS
    Publication number: 20130108583
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: May 18, 2012
    Publication date: May 2, 2013
    Inventors: Alfredo C. Castro, Michael J. Grogan, William Matsui, Karen J. McGovern, Martin R. Tremblay
  • METHODS OF USE OF CYCLOPAMINE ANALOGS
    Publication number: 20130108582
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: May 18, 2012
    Publication date: May 2, 2013
    Inventors: Alfredo C. Castro, Michael J. Grogan, William Matsui, Karen J. McGovern, Martin R. Tremblay