Patents by Inventor Karen Robins

Karen Robins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetic engineering process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide by microorganisms
    Patent number: 5427934
    Abstract: A genetic engineering process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide. For this purpose, a new DNA is isolated from a microorganism that codes for a stereospecific hydrolase. This DNA is then ligated in an expression vector, and a hybrid plasmid results, which is transformed into microorganisms. These microorganisms are then able to biotransform the R-(-) isomer in racemic R,S-(.+-.)-2,2-dimethylcyclopropanecarboxamide into R-(-)-2,2-dimethylcyclopropanecarboxylic acid, and optionally active S-(+)-2,2-dimethylcyclopropanecarboxamide is obtained.
    Type: Grant
    Filed: July 24, 1992
    Date of Patent: June 27, 1995
    Assignee: Lonza Ltd.
    Inventors: Thomas Zimmermann, Karen Robins, Olwen M. Birch, Elisabeth Bohlen
  • Biotechnological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide
    Patent number: 5273903
    Abstract: A microbiological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide, starting from R,S-(.+-.)-2,2-dimethylcyclopropanecarboxamide. For this process, new microorganisms are selected and isolated, which are capable of biotransforming R-(-)-2,2-dimethylcyclopropanecarboxamide in racemic 2,2-dimethylcyclopropanecarboxamide to R-(-)-2,2-dimethylcyclopropanecarboxylic acid. The process can then be performed either with the microorganisms or with the cell-free enzymes from the microorganisms.
    Type: Grant
    Filed: March 3, 1992
    Date of Patent: December 28, 1993
    Assignee: Lonza Ltd.
    Inventors: Karen Robins, Thomas Gilligan