Patents by Inventor Karl-Heinz Baringhaus

Karl-Heinz Baringhaus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-oxoisoxazoles as inhibitors of lipases and phospholipases
    Patent number: 9029400
    Abstract: The present invention relates to 5-oxoisoxazole derivatives of the formula I, the pharmaceutically usable salts thereof and the use thereof as medicinal substances.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: May 12, 2015
    Assignee: Sanofi
    Inventors: Stefan Petry, Manfred Seidel, Gerhard Zoller, Gunter Müller, Karl-Heinz Baringhaus, Hubert Heuer
  • Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
    Patent number: 8933024
    Abstract: The present invention relates to azolopyridin-3-one derivatives of the general formula (I) with the meanings specified in the description, to their pharmaceutically usable salts and to their use as drug substances.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: January 13, 2015
    Assignee: Sanofi
    Inventors: Stefan Petry, Norbert Tennagels, Karl-Heinz Baringhaus
  • AZOLOPYRIDIN-3-ONE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES
    Publication number: 20130157941
    Abstract: The present invention relates to azolopyridin-3-one derivatives of the general formula (I) with the meanings specified in the description, to their pharmaceutically usable salts and to their use as drug substances.
    Type: Application
    Filed: June 17, 2011
    Publication date: June 20, 2013
    Applicant: Sanofi
    Inventors: Stefan Petry, Norbert Tennagels, Karl-Heinz Baringhaus
  • Indazole derivatives as inhibitors of hormone sensitive lipase
    Patent number: 7968719
    Abstract: The present invention relates to indazole derivatives of the general formulae I or II having the meanings indicated in the description, to the pharmaceutically useful salts thereof and the use thereof as drugs.
    Type: Grant
    Filed: April 28, 2009
    Date of Patent: June 28, 2011
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Gerhard Zoller, Stefan Petry, Gunter Muller, Hubert Heuer, Karl-Heinz Baringhaus
  • Substituted N-aminomethylene sulfonamides, production and use thereof as medicaments
    Patent number: 7781613
    Abstract: Disclosed are compounds of the general formula (I), with the definitions of the substituents R1 to R5, A and X being detailed in the text, and to their physiologically tolerated salts, to processes for preparing these compounds and to the use thereof as inhibitors of hormone-sensitive lipase (HSL).
    Type: Grant
    Filed: June 25, 2007
    Date of Patent: August 24, 2010
    Assignee: Sanofi-Aventis
    Inventors: Karl Schoenafinger, Stefan Petry, Guenter Mueller, Karl-Heinz Baringhaus
  • TRIAZOLOPYRIDINE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES
    Publication number: 20100190801
    Abstract: The invention relates to triazolopyridine derivatives of general formula (I), which are defined as cited in the description, to their pharmaceutically applicable salts and to their use as medicaments.
    Type: Application
    Filed: March 25, 2010
    Publication date: July 29, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Stefan PETRY, Gerhard ZOLLER, Günter MÜLLER, Karl-Heinz BARINGHAUS, Hubert HEUER
  • Diphenylamine-substituted salicylthiazole derivatives and related compounds as phosphotyrosine phosphatase 1B (PTB1B) inhibitors for using as blood-sugar decreasing active ingredients for treating diabetes
    Patent number: 7741491
    Abstract: The invention therefore relates to compounds of the formula I in which the variables are as defined in the specification, to pharmaceutical compositions containing them and to their use for therapeutically lowering blood glucose levels.
    Type: Grant
    Filed: December 12, 2006
    Date of Patent: June 22, 2010
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Stefan Petry, Karl-Heinz Baringhaus, Norbert Tennangels, Guenter Mueller, Reinhard Kirsch
  • 5-Oxoisoxazoles as inhibitors of lipases and phospholipases
    Publication number: 20100152246
    Abstract: The present invention relates to 5-oxoisoxazole derivatives of the formula I, the pharmaceutically usable salts thereof and the use thereof as medicinal substances.
    Type: Application
    Filed: October 5, 2009
    Publication date: June 17, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Stefan PETRY, Manfred SEIDEL, Gerhard ZOLLER, Gunter MÜLLER, Karl-Heinz BARINGHAUS, Hubert HEUER
  • Pyrimido[5,4-e][1,2,4]triazine-5-7-diones, processes for preparing them and their use
    Patent number: 7737144
    Abstract: The invention relates to pyrimido[5,4-e][1,2,4]triazine-5,7-diones, pharmaceutically acceptable salts thereof and physiologically functional derivatives. The invention therefore relates to compounds of the formula I, in which the radicals have the given meanings, and to their physiologically tolerated salts and processes for preparing them. The compounds are suitable for use as antidiabetics, for example.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: June 15, 2010
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Stefan Petry, Karl-Heinz Baringhaus, Norbert Tennagels, Guenter Mueller
  • Triazolopyridine derivatives as inhibitors of lipases and phospholipases
    Patent number: 7718669
    Abstract: The invention relates to triazolopyridine derivatives of general formula (I), which are defined as cited in the description, to their pharmaceutically applicable salts and to their use as medicaments.
    Type: Grant
    Filed: April 9, 2008
    Date of Patent: May 18, 2010
    Assignee: Sanofi-Aventis
    Inventors: Stefan Petry, Gerhard Zoller, Günter Müller, Karl-Heinz Baringhaus, Hubert Heuer
  • INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE SENSITIVE LIPASE
    Publication number: 20090215824
    Abstract: The present invention relates to indazole derivatives of the general formulae I or II having the meanings indicated in the description, to the pharmaceutically useful salts thereof and the use thereof as drugs.
    Type: Application
    Filed: April 28, 2009
    Publication date: August 27, 2009
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Gerhard Zoller, Stefan Petry, Gunter Muller, Hubert Heuer, Karl-Heinz Baringhaus
  • Indazole derivatives as inhibitors of hormone sensitive lipase
    Patent number: 7528155
    Abstract: The present invention relates to indazole derivatives of the general formulae I or II having the meanings indicated in the description, to the pharmaceutically useful salts thereof and the use thereof as drugs.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: May 5, 2009
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Gerhard Zoller, Stefan Petry, Gunter Muller, Hubert Heuer, Karl-Heinz Baringhaus
  • TRIAZOLOPYRIDINE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES
    Publication number: 20090030011
    Abstract: The invention relates to triazolopyridine derivatives of general formula (I), which are defined as cited in the description, to their pharmaceutically applicable salts and to their use as medicaments.
    Type: Application
    Filed: April 9, 2008
    Publication date: January 29, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Stefan Petry, Gerhard Zoller, Gunter Muller, Karl-Heinz Baringhaus, Hubert Heuer
  • Hydroxybiphenyl carboxylic acids and derivatives, method for producing the same and their use
    Patent number: 7453009
    Abstract: Disclosed are novel compound of formula I, As defined herein and their use as pharmaceutically active compounds for reducing blood glucose, and/or treating one or more of type II diabetes, disturbances of lipid and carbohydrate metabolism, arteriosclerotic manifestations, and insulin resistance.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: November 18, 2008
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Stefan Petry, Karl-Heinz Baringhaus, Norbert Tennagels, Gunter Muller
  • Substituted oxazolobenzoisothiazole dioxide derivatives method for production and use thereof
    Patent number: 7453000
    Abstract: The invention relates to compounds of formula (I), where the groups have the meanings set forth herein and the physiologically-acceptable salts thereof. The compounds are suitable as medicaments for lowering blood sugar levels and for prevention and treatment of diabetes.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: November 18, 2008
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Stefan Petry, Norbert Tennagels, Reinhard Kirsch, Karl-Heinz Baringhaus
  • SUBSTITUTED N-AMINOMETHYLENE SULFONAMIDES, PRODUCTION AND USE THEREOF AS MEDICAMENTS
    Publication number: 20080069851
    Abstract: Disclosed are compounds of the general formula (I), with the definitions of the substituents R1 to R5, A and X being detailed in the text, and to their physiologically tolerated salts, to processes for preparing these compounds and to the use thereof as inhibitors of hormone-sensitive lipase (HSL).
    Type: Application
    Filed: June 25, 2007
    Publication date: March 20, 2008
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Karl SCHOENAFINGER, Stefan PETRY, Guenter MUELLER, Karl-Heinz BARINGHAUS
  • Pyrimido[5,4-e][1,2,4]triazine-5,7-diones, processes for preparing them and their use
    Publication number: 20080032984
    Abstract: The invention relates to pyrimido[5,4-e][1,2,4]triazine-5,7-diones, pharmaceutically acceptable salts thereof and physiologically functional derivatives. The invention therefore relates to compounds of the formula I, in which the radicals have the given meanings, and to their physiologically tolerated salts and processes for preparing them. The compounds are suitable for use as antidiabetics, for example.
    Type: Application
    Filed: June 28, 2007
    Publication date: February 7, 2008
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Stefan Petry, Karl-Heinz Baringhaus, Norbert Tennagels, Guenter Mueller
  • HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE
    Publication number: 20080027134
    Abstract: Disclosed are novel compound of formula I, As defined herein and their use as pharmaceutically active compounds for reducing blood glucose, and/or treating one or more of type II diabetes, disturbances of lipid and carbohydrate metabolism, arteriosclerotic manifestations, and insulin resistance.
    Type: Application
    Filed: June 8, 2007
    Publication date: January 31, 2008
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Stefan PETRY, Karl-Heinz BARINGHAUS, Norbert TENNAGELS, Gunter MULLER
  • DIPHENYLAMINE-SUBSTITUTED SALICYLTHIAZOLE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOTYROSINE PHOSPHATASE 1B (PTB1B) INHIBITORS FOR USING AS BLOOD-SUGAR DECREASING ACTIVE INGREDIENTS FOR TREATING DIABETES
    Publication number: 20070191441
    Abstract: The invention therefore relates to compounds of the formula I in which the variables are as defined in the specification, to pharmaceutical compositions containing them and to their use for therapeutically lowering blood glucose levels.
    Type: Application
    Filed: December 12, 2006
    Publication date: August 16, 2007
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Stefan Petry, Karl-Heinz Baringhaus, Norbert Tennagels, Guenter Mueller, Reinhard Kirsch
  • SUBSTITUTED OXAZOLOBENZOISOTHIAZOLE DIOXIDE DERIVATIVES METHOD FOR PRODUCTION AND USE THEREOF
    Publication number: 20070149511
    Abstract: The invention relates to compounds of formula (I), where the groups have the meanings set forth herein and the physiologically-acceptable salts thereof. The compounds are suitable as medicaments for lowering blood sugar levels and for prevention and treatment of diabetes.
    Type: Application
    Filed: November 16, 2006
    Publication date: June 28, 2007
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Stefan Petry, Norbert Tennagels, Reinhard Kirsch, Karl-Heinz Baringhaus