Patents by Inventor Karl-Heinz Baringhaus

Karl-Heinz Baringhaus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals
    Patent number: 5658933
    Abstract: The invention relates to compounds of the formula I, ##STR1## to a process for their preparation and to their use as pharmaceuticals. The compounds are employed, in particular, as ester prodrugs of prolyl hydroxylase inhibitors for inhibiting collagen biosynthesis and as fibrosuppressive agents.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: August 19, 1997
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Klaus Weidmann, Karl-Heinz Baringhaus, Georg Tschank, Martin Bickel
  • Substituted heterocyclic carboxyamides, their preparation and their use as pharmaceuticals
    Patent number: 5620995
    Abstract: The invention relates to compounds of the formula I, to a process for their preparation and to their use as pharmaceuticals. ##STR1## In particular, the compounds are used as inhibitors of prolyl-4-hydroxylase and as inhibitors of collagen biosynthesis, as pharmaceuticals against fibrotic diseases of the liver, the lung and the skin.
    Type: Grant
    Filed: December 28, 1994
    Date of Patent: April 15, 1997
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Klaus Weidmann, Karl-Heinz Baringhaus, Georg Tschank, Martin Bickel
  • Acylsulfonamido- and sulfonamidopyridine-2-carboxylic acid esters and their pyridine N-oxides, processes for their preparation and their use as medicaments
    Patent number: 5428046
    Abstract: The invention relates to acylsulfonamido- and sulfonamidopyridine-2-carboxylic acid esters and their pyridine N-oxides of the formula I ##STR1## in which______________________________________ A = R.sup.3 and B = X--NR.sup.5 R.sup.6 or B = R.sup.3 and A = X--NR.sup.5 R.sup.6. ______________________________________The compounds are suitable as medicaments against fibrotic diseases.
    Type: Grant
    Filed: September 22, 1993
    Date of Patent: June 27, 1995
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Klaus Weidmann, Martin Bickel, Volkmar Gunzler-Pukall, Karl-Heinz Baringhaus